Research Topics

Pauline Mendola


Affiliation: National Institutes of Health
Country: USA


  1. Nobles C, Grantz K, Liu D, Williams A, Ouidir M, Seeni I, et al. Ambient air pollution and fetal growth restriction: Physician diagnosis of fetal growth restriction versus population-based small-for-gestational age. Sci Total Environ. 2019;650:2641-2647 pubmed publisher
    ..Associations with SGA were less clear. Chronic exposure to air pollution may be associated with FGR but not SGA in this low-risk population. ..
  2. Seeni I, Ha S, Nobles C, Liu D, Sherman S, Mendola P. Air pollution exposure during pregnancy: maternal asthma and neonatal respiratory outcomes. Ann Epidemiol. 2018;28:612-618.e4 pubmed publisher
    ..No interaction with maternal asthma was observed. Restriction to term births yielded similar results. Several pollutants appear to increase neonatal respiratory outcome risks. ..
  3. Mendola P, Männistö T, Leishear K, Reddy U, Chen Z, Laughon S. Neonatal health of infants born to mothers with asthma. J Allergy Clin Immunol. 2014;133:85-90.e1-4 pubmed publisher
    ..Adverse neonatal outcomes, including respiratory complications, hyperbilirubinemia, and NICU admission, were increased in association with maternal asthma even among term deliveries. ..
  4. Williams A, Wallace M, Nobles C, Mendola P. Racial residential segregation and racial disparities in stillbirth in the United States. Health Place. 2018;51:208-216 pubmed publisher
    ..Decreasing segregation may prevent approximately 900 stillbirths annually among U.S. blacks. Reducing structural racism, segregation in particular, could help reduce black-white stillbirth disparities. ..
  5. Zhu Y, Zhang C, Liu D, Grantz K, Wallace M, Mendola P. Maternal ambient air pollution exposure preconception and during early gestation and offspring congenital orofacial defects. Environ Res. 2015;140:714-20 pubmed publisher
    ..Exposure to several criteria air pollutants preconception and during early gestation was associated with elevated odds for CP, while CL ±CP was only associated with preconception SO2 exposure. ..
  6. Hines E, Mendola P, von Ehrenstein O, Ye X, Calafat A, Fenton S. Concentrations of environmental phenols and parabens in milk, urine and serum of lactating North Carolina women. Reprod Toxicol. 2015;54:120-8 pubmed publisher
    ..These pilot data suggest that nursing mothers are exposed to phenols and parabens; urine is the best measurement matrix; and correlations between chemical and endogenous immune-related biomarkers merit further investigation. ..
  7. Mendola P, Wallace M, Hwang B, Liu D, Robledo C, Männistö T, et al. Preterm birth and air pollution: Critical windows of exposure for women with asthma. J Allergy Clin Immunol. 2016;138:432-440.e5 pubmed publisher
    ..Mothers with asthma may experience a higher risk for PTB after exposure to traffic-related pollutants such as CO and NOx, particularly for exposures 3-months preconception and in the early weeks of pregnancy. ..
  8. Wallace M, Hoyert D, Williams C, Mendola P. Pregnancy-associated homicide and suicide in 37 US states with enhanced pregnancy surveillance. Am J Obstet Gynecol. 2016;215:364.e1-364.e10 pubmed publisher
    ..62, 95% confidence interval, 0.57-0.68). Pregnancy and postpartum appear to be times of increased risk for homicide and decreased risk for suicide among women in the United States. ..
  9. Mendola P, Wallace M, Liu D, Robledo C, MÓ“nnistÓ§ T, Grantz K. Air pollution exposure and preeclampsia among US women with and without asthma. Environ Res. 2016;148:248-255 pubmed publisher
    ..Significant interactions were observed for nearly all VOCs and asthmatics had higher risk during all time windows for benzene, ethylbenzene, m-xylene, o-xylene, p-xylene and toluene while most PAHs did not increase risk. ..

More Information


  1. Wallace M, Mendola P, Chen Z, Hwang B, Grantz K. Preterm Birth in the Context of Increasing Income Inequality. Matern Child Health J. 2016;20:164-71 pubmed publisher
    ..The contextual effect of increasing income inequality on preterm birth risk merits further study. ..
  2. Mendola P, Sundaram R, Louis G, Sun L, Wallace M, Smarr M, et al. Proximity to major roadways and prospectively-measured time-to-pregnancy and infertility. Sci Total Environ. 2017;576:172-177 pubmed publisher
    ..Our findings suggest that proximity to major roadways may be related to reductions in fecundity. Prospective data from larger populations is warranted to corroborate these findings. ..
  3. Nobles C, Schisterman E, Ha S, Kim K, Mumford S, Buck Louis G, et al. Ambient air pollution and semen quality. Environ Res. 2018;163:228-236 pubmed publisher
    ..40, 1.66) greater percent sperm head with acrosome. Air pollution exposure was not associated with semen quality, except for sperm head parameters. Moderate levels of ambient air pollution may not be a major contributor to semen quality. ..
  4. Flores K, Robledo C, Hwang B, Leishear K, Laughon Grantz K, Mendola P. Does maternal asthma contribute to racial/ethnic disparities in obstetrical and neonatal complications?. Ann Epidemiol. 2015;25:392-397.e1 pubmed publisher
    ..Despite their increased risk for both asthma and many complications, our findings for black women were null. Asthma did not contribute to racial/ethnic disparities in complications. ..
  5. Ha S, Männistö T, Liu D, Sherman S, Ying Q, Mendola P. Air pollution and cardiovascular events at labor and delivery: a case-crossover analysis. Ann Epidemiol. 2017;27:377-383 pubmed publisher
    ..Inverse associations were observed for O3 and some PM constituents as well as air toxics. Cardiovascular events at labor/delivery merit more attention in relation to air pollution. ..
  6. Mendola P, Ha S, Pollack A, Zhu Y, Seeni I, Kim S, et al. Chronic and Acute Ozone Exposure in the Week Prior to Delivery Is Associated with the Risk of Stillbirth. Int J Environ Res Public Health. 2017;14: pubmed publisher
    ..Both chronic and acute O₃ exposure consistently increased stillbirth risk, while the role of other pollutants varied. Approximately 8000 stillbirths per year in the US may be attributable to O₃ exposure. ..
  7. Ha S, Nguyen K, Liu D, Männistö T, Nobles C, Sherman S, et al. Ambient temperature and risk of cardiovascular events at labor and delivery: A case-crossover study. Environ Res. 2017;159:622-628 pubmed publisher
    ..Small changes in temperature appear to affect the risk of having cardiovascular events at labor/delivery. Black women had a differentially higher warm season risk. These findings merit further investigation. ..
  8. Mendola P, Brett K, Dibari J, Pollack A, Tandon R, Shenassa E. Menopause and lead body burden among US women aged 45-55, NHANES 1999-2010. Environ Res. 2013;121:110-3 pubmed publisher
    ..Blood lead was associated with natural menopause in US women even after adjustment for bone turnover. This raises concern that lead exposure, even at low levels, may shorten women's reproductive lifespan. ..
  9. Ha S, Zhu Y, Liu D, Sherman S, Mendola P. Ambient temperature and air quality in relation to small for gestational age and term low birthweight. Environ Res. 2017;155:394-400 pubmed publisher
    ..Our findings suggest prenatal exposures to extreme ambient temperature relative to usual environment may increase tLBW risk. Given concerns related to climate change, these findings merit further investigation. ..
  10. Ha S, Sundaram R, Buck Louis G, Nobles C, Seeni I, Sherman S, et al. Ambient air pollution and the risk of pregnancy loss: a prospective cohort study. Fertil Steril. 2018;109:148-153 pubmed publisher