Dorian B McGavern

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi A little 'help' from IL-21 during persistent viral infection
    Dorian B McGavern
    National Institute of Neurological Disorders and Stroke, The National Institutes of Health, Bethesda, MD 20892, USA
    J Mol Cell Biol 2:8-10. 2010
  2. ncbi Illuminating viral infections in the nervous system
    Dorian B McGavern
    National Institute of Neurological Disorders and Stroke, The National Institutes of Health, Bethesda, Maryland 20892, USA
    Nat Rev Immunol 11:318-29. 2011
  3. ncbi Therapeutic memory T cells require costimulation for effective clearance of a persistent viral infection
    Lucile Garidou
    National Institute of Neurological Disorders and Stroke, The National Institutes of Health, Bethesda, Maryland 20882, USA
    J Virol 83:8905-15. 2009
  4. ncbi Inflammation on the mind: visualizing immunity in the central nervous system
    Silvia S Kang
    National Institutes of Neurological Disorders and Stroke, National Institutes of Health, 10 Center Drive, Bethesda, MD 20892, USA
    Curr Top Microbiol Immunol 334:227-63. 2009
  5. ncbi Therapeutic blockade of transforming growth factor beta fails to promote clearance of a persistent viral infection
    Lucile Garidou
    National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA
    J Virol 86:7060-71. 2012
  6. ncbi Microbial induction of vascular pathology in the CNS
    Silvia S Kang
    National Institute of Neurological Disorders and Stroke, The National Institutes of Health, 10 Center Drive, Bethesda, MD 20892, USA
    J Neuroimmune Pharmacol 5:370-86. 2010
  7. ncbi Migration of cytotoxic lymphocytes in cell cycle permits local MHC I-dependent control of division at sites of viral infection
    Silvia S Kang
    National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
    J Exp Med 208:747-59. 2011
  8. ncbi Two-photon imaging of microbial immunity in living tissues
    Jasmin Herz
    National Institute of Neurological Disorders and Stroke, The National Institutes of Health, Bethesda, MD 20892, USA
    Microsc Microanal 18:730-41. 2012
  9. ncbi Persistent viral infection elevates central nervous system MHC class I through chronic production of interferons
    Phi Truong
    National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
    J Immunol 183:3895-905. 2009

Collaborators

  • David G Brooks
  • Jiyun V Kim
  • Silvia S Kang
  • Lucile Garidou
  • Jasmin Herz
  • Sara Heydari
  • Phi Truong
  • Selamawit Gossa
  • Bernd H Zinselmeyer
  • Phillip Stewart-Hutchinson
  • Michael L Dustin
  • Debasis Nayak

Detail Information

Publications9

  1. ncbi A little 'help' from IL-21 during persistent viral infection
    Dorian B McGavern
    National Institute of Neurological Disorders and Stroke, The National Institutes of Health, Bethesda, MD 20892, USA
    J Mol Cell Biol 2:8-10. 2010
    ..Three recent studies suggest that CD4(+) T cells accomplish this in part through the release of IL-21...
  2. ncbi Illuminating viral infections in the nervous system
    Dorian B McGavern
    National Institute of Neurological Disorders and Stroke, The National Institutes of Health, Bethesda, Maryland 20892, USA
    Nat Rev Immunol 11:318-29. 2011
    ..A special emphasis is placed on immune surveillance of persistent and latent viral infections and on recent insights gained from imaging both protective and pathogenic antiviral immune responses...
  3. ncbi Therapeutic memory T cells require costimulation for effective clearance of a persistent viral infection
    Lucile Garidou
    National Institute of Neurological Disorders and Stroke, The National Institutes of Health, Bethesda, Maryland 20882, USA
    J Virol 83:8905-15. 2009
    ....
  4. ncbi Inflammation on the mind: visualizing immunity in the central nervous system
    Silvia S Kang
    National Institutes of Neurological Disorders and Stroke, National Institutes of Health, 10 Center Drive, Bethesda, MD 20892, USA
    Curr Top Microbiol Immunol 334:227-63. 2009
    ..This review will focus on how imaging techniques have elevated our understanding of CNS inflammation as well as the exciting prospects that lie ahead as we begin to pursue investigation of the inflamed CNS in real time...
  5. ncbi Therapeutic blockade of transforming growth factor beta fails to promote clearance of a persistent viral infection
    Lucile Garidou
    National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA
    J Virol 86:7060-71. 2012
    ..These data suggest that therapeutic neutralization of TGF-β is not an efficacious means to promote clearance of a persistent viral infection...
  6. ncbi Microbial induction of vascular pathology in the CNS
    Silvia S Kang
    National Institute of Neurological Disorders and Stroke, The National Institutes of Health, 10 Center Drive, Bethesda, MD 20892, USA
    J Neuroimmune Pharmacol 5:370-86. 2010
    ..Emphasis is placed on CNS diseases that result from a pathogenic interplay between host immune defenses and the invading microbe...
  7. ncbi Migration of cytotoxic lymphocytes in cell cycle permits local MHC I-dependent control of division at sites of viral infection
    Silvia S Kang
    National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
    J Exp Med 208:747-59. 2011
    ..These results demonstrate that CTLs are poised to divide in transit and that their numbers can be influenced locally at the site of infection through interactions with cells displaying cognate antigen...
  8. ncbi Two-photon imaging of microbial immunity in living tissues
    Jasmin Herz
    National Institute of Neurological Disorders and Stroke, The National Institutes of Health, Bethesda, MD 20892, USA
    Microsc Microanal 18:730-41. 2012
    ..This review focuses on how two-photon microscopy can be used to study tissue-specific immune responses in vivo, and how this approach has advanced our understanding of host-immune interactions following infection...
  9. ncbi Persistent viral infection elevates central nervous system MHC class I through chronic production of interferons
    Phi Truong
    National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
    J Immunol 183:3895-905. 2009
    ....