A McCampbell

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint CREB-binding protein sequestration by expanded polyglutamine
    A McCampbell
    Neurogenetics Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, 10 Center Drive, Building 10, Room 3B11, Bethesda, MD 20892 1250, USA
    Hum Mol Genet 9:2197-202. 2000
  2. pmc Histone deacetylase inhibitors reduce polyglutamine toxicity
    A McCampbell
    Neurogenetics Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Building 10, Room 3B14, 10 Center Drive, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 98:15179-84. 2001

Detail Information

Publications2

  1. ncbi request reprint CREB-binding protein sequestration by expanded polyglutamine
    A McCampbell
    Neurogenetics Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, 10 Center Drive, Building 10, Room 3B11, Bethesda, MD 20892 1250, USA
    Hum Mol Genet 9:2197-202. 2000
    ..Finally, we demonstrate that over-expression of CBP rescues cells from polyglutamine-mediated toxicity in neuronal cell culture. These data support a CBP-sequestration model of polyglutamine expansion disease...
  2. pmc Histone deacetylase inhibitors reduce polyglutamine toxicity
    A McCampbell
    Neurogenetics Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Building 10, Room 3B14, 10 Center Drive, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 98:15179-84. 2001
    ..These findings suggest that nuclear accumulation of polyglutamine can lead to altered protein acetylation in neurons and indicate a novel therapeutic strategy for polyglutamine disease...