Masayuki Matsumoto

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Two types of dopamine neuron distinctly convey positive and negative motivational signals
    Masayuki Matsumoto
    Laboratory of Sensorimotor Research, National Eye Institute, National Institutes of Health, Bethesda, Maryland 20892 4435, USA
    Nature 459:837-41. 2009
  2. pmc Representation of negative motivational value in the primate lateral habenula
    Masayuki Matsumoto
    Laboratory of Sensorimotor Research, National Eye Institute, US National Institutes of Health, 49 Convent Drive, Bethesda, Maryland 20892 4435, USA
    Nat Neurosci 12:77-84. 2009
  3. pmc Distinct tonic and phasic anticipatory activity in lateral habenula and dopamine neurons
    Ethan S Bromberg-Martin
    Laboratory of Sensorimotor Research, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Neuron 67:144-55. 2010
  4. pmc A pallidus-habenula-dopamine pathway signals inferred stimulus values
    Ethan S Bromberg-Martin
    Laboratory of Sensorimotor Research, National Eye Institute, National Institutes of Health, Bldg 49, Rm 2A50, Bethesda, Maryland 20892 4435, USA
    J Neurophysiol 104:1068-76. 2010
  5. pmc Multiple timescales of memory in lateral habenula and dopamine neurons
    Ethan S Bromberg-Martin
    Laboratory of Sensorimotor Research, National Eye Institute, Bethesda, MD 20892, USA
    Neuron 67:499-510. 2010
  6. pmc Negative motivational control of saccadic eye movement by the lateral habenula
    Masayuki Matsumoto
    Laboratory of Sensorimotor Research, National Eye Institute, National Institutes of Health, Bethesda, MD, USA
    Prog Brain Res 171:399-402. 2008
  7. pmc Dopamine in motivational control: rewarding, aversive, and alerting
    Ethan S Bromberg-Martin
    Laboratory of Sensorimotor Research, National Eye Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    Neuron 68:815-34. 2010
  8. ncbi request reprint Lateral habenula as a source of negative reward signals in dopamine neurons
    Masayuki Matsumoto
    Laboratory of Sensorimotor Research, National Eye Institute, National Institutes of Health, Bethesda, Maryland 20892 4435, USA
    Nature 447:1111-5. 2007
  9. ncbi request reprint [Role of the lateral habenula and dopamine neurons in reward processing]
    Masayuki Matsumoto
    Laboratory of Sensorimotor Research, National Eye Institute, National Institutes of Health, 49 Convent Drive, Bldg 49, Rm 2A50, Bethesda, MD 20892 4435, USA
    Brain Nerve 61:389-96. 2009
  10. pmc New insights on the subcortical representation of reward
    Okihide Hikosaka
    National Eye Institute, National Institutes of Health, Bethesda, MD 20892 4435, USA
    Curr Opin Neurobiol 18:203-8. 2008

Detail Information

Publications12

  1. pmc Two types of dopamine neuron distinctly convey positive and negative motivational signals
    Masayuki Matsumoto
    Laboratory of Sensorimotor Research, National Eye Institute, National Institutes of Health, Bethesda, Maryland 20892 4435, USA
    Nature 459:837-41. 2009
    ..A similar anatomical difference was observed for their responses to actual airpuffs. These findings suggest that different groups of dopamine neurons convey motivational signals in distinct manners...
  2. pmc Representation of negative motivational value in the primate lateral habenula
    Masayuki Matsumoto
    Laboratory of Sensorimotor Research, National Eye Institute, US National Institutes of Health, 49 Convent Drive, Bethesda, Maryland 20892 4435, USA
    Nat Neurosci 12:77-84. 2009
    ..These results suggest that the lateral habenula has the potential to adaptively control both reward-seeking and punishment-avoidance behaviors, presumably through its projections to dopaminergic and serotonergic systems...
  3. pmc Distinct tonic and phasic anticipatory activity in lateral habenula and dopamine neurons
    Ethan S Bromberg-Martin
    Laboratory of Sensorimotor Research, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Neuron 67:144-55. 2010
    ..Our data suggest that the habenula-dopamine pathway motivates anticipation through a combination of tonic reward-related and phasic salience-related signals...
  4. pmc A pallidus-habenula-dopamine pathway signals inferred stimulus values
    Ethan S Bromberg-Martin
    Laboratory of Sensorimotor Research, National Eye Institute, National Institutes of Health, Bldg 49, Rm 2A50, Bethesda, Maryland 20892 4435, USA
    J Neurophysiol 104:1068-76. 2010
    ..Our data indicate that the pallidus-habenula-dopamine pathway signals reward values estimated through both experience and inference...
  5. pmc Multiple timescales of memory in lateral habenula and dopamine neurons
    Ethan S Bromberg-Martin
    Laboratory of Sensorimotor Research, National Eye Institute, Bethesda, MD 20892, USA
    Neuron 67:499-510. 2010
    ..Our data show that the habenula-dopamine pathway contains multiple timescales of memory and provide evidence for their role in motivated behavior...
  6. pmc Negative motivational control of saccadic eye movement by the lateral habenula
    Masayuki Matsumoto
    Laboratory of Sensorimotor Research, National Eye Institute, National Institutes of Health, Bethesda, MD, USA
    Prog Brain Res 171:399-402. 2008
    ..We will then describe our own study. Finally, we will discuss how the lateral habenula, as well as dopamine neurons, contributes to the reward-based control of saccadic eye movements...
  7. pmc Dopamine in motivational control: rewarding, aversive, and alerting
    Ethan S Bromberg-Martin
    Laboratory of Sensorimotor Research, National Eye Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    Neuron 68:815-34. 2010
    ..We hypothesize that these dopaminergic pathways for value, salience, and alerting cooperate to support adaptive behavior...
  8. ncbi request reprint Lateral habenula as a source of negative reward signals in dopamine neurons
    Masayuki Matsumoto
    Laboratory of Sensorimotor Research, National Eye Institute, National Institutes of Health, Bethesda, Maryland 20892 4435, USA
    Nature 447:1111-5. 2007
    ..These results suggest that the inhibitory input from the lateral habenula plays an important role in determining the reward-related activity of dopamine neurons...
  9. ncbi request reprint [Role of the lateral habenula and dopamine neurons in reward processing]
    Masayuki Matsumoto
    Laboratory of Sensorimotor Research, National Eye Institute, National Institutes of Health, 49 Convent Drive, Bldg 49, Rm 2A50, Bethesda, MD 20892 4435, USA
    Brain Nerve 61:389-96. 2009
    ..Thereby, the lateral habenula could contribute to reward-seeking behaviors through its projections to the dopaminergic systems...
  10. pmc New insights on the subcortical representation of reward
    Okihide Hikosaka
    National Eye Institute, National Institutes of Health, Bethesda, MD 20892 4435, USA
    Curr Opin Neurobiol 18:203-8. 2008
    ..Such reward-related neurons are found in the areas which have been associated with stress, pain, mood, emotion, memory, and arousal. These results suggest that reward needs to be understood in a larger framework of animal behavior...
  11. pmc Electrical stimulation of the primate lateral habenula suppresses saccadic eye movement through a learning mechanism
    Masayuki Matsumoto
    Laboratory of Sensorimotor Research, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS ONE 6:e26701. 2011
    ..Together with previous studies showing LHb activation by reward omission and aversive stimuli, the present stimulation experiment suggests that LHb activity contributes to learning to suppress actions which lead to unpleasant events...
  12. pmc Reward-dependent modulation of neuronal activity in the primate dorsal raphe nucleus
    Kae Nakamura
    Laboratory of Sensorimotor Research, National Eye Institute National Institutes of Health, Bethesda, Maryland 20892 4435, USA
    J Neurosci 28:5331-43. 2008
    ..These results suggest that the DRN, probably including serotonin neurons, signals the reward value associated with the current behavior...