Research Topics
| Mary Jane MassonSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Lymphocyte loss and immunosuppression following acetaminophen-induced hepatotoxicity in mice as a potential mechanism of toleranceMary Jane Masson
Molecular and Cellular Toxicology Section, Laboratory of Molecular Immunology, National Heart, Lung, and Blood Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
Chem Res Toxicol 20:20-6. 2007..Similar regulatory pathways may inhibit other hepatotoxic drugs from causing allergic reactions...
Pathologic role of stressed-induced glucocorticoids in drug-induced liver injury in miceMary Jane Masson
Molecular and Cellular Toxicology Section, Laboratory of Molecular Immunology, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA
Biochem Biophys Res Commun 397:453-8. 2010....
Pathogenic role of natural killer T and natural killer cells in acetaminophen-induced liver injury in mice is dependent on the presence of dimethyl sulfoxideMary Jane Masson
Molecular and Cellular Toxicology Section, Laboratory of Molecular Immunology, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA
Hepatology 48:889-97. 2008..CONCLUSION: These data demonstrate a previously unappreciated effect of DMSO on hepatic NKT and NK cells, suggesting that DMSO should be used cautiously in experiments involving these cells...
Hepatoprotective role of endogenous interleukin-13 in a murine model of acetaminophen-induced liver diseaseSteven B Yee
Molecular and Cellular Toxicology Section, Laboratory of Molecular Immunology, National Heart, Lung, and Blood Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
Chem Res Toxicol 20:734-44. 2007....
Evidence of an immune-mediated mechanism for an idiosyncratic nevirapine-induced reaction in the female Brown Norway ratJacintha M Shenton
Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada
Chem Res Toxicol 18:1799-813. 2005..In particular, the finding that CD4+ T cells may play a central role in this model fits with the observation that the incidence of idiosyncratic reactions to nevirapine in humans appears to be lower in patients with low CD4+ counts...
