Dragan Maric

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc SUMOylation participates in induction of ischemic tolerance
    Yang ja Lee
    Stroke Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA
    J Neurochem 109:257-67. 2009
  2. pmc Alpha-synuclein overexpression increases dopamine toxicity in BE2-M17 cells
    Marco Bisaglia
    Department of Biology, University of Padova, 35121 Padova, Italy
    BMC Neurosci 11:41. 2010
  3. ncbi request reprint Self-renewing and differentiating properties of cortical neural stem cells are selectively regulated by basic fibroblast growth factor (FGF) signaling via specific FGF receptors
    Dragan Maric
    Laboratory of Neurophysiology, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Neurosci 27:1836-52. 2007
  4. ncbi request reprint GABA expression dominates neuronal lineage progression in the embryonic rat neocortex and facilitates neurite outgrowth via GABA(A) autoreceptor/Cl- channels
    D Maric
    Laboratory of Neurophysiology, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Neurosci 21:2343-60. 2001
  5. ncbi request reprint Neural stem cells redefined: a FACS perspective
    Dragan Maric
    Laboratory of Neurophysiology, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
    Mol Neurobiol 30:49-76. 2004
  6. ncbi request reprint Prospective cell sorting of embryonic rat neural stem cells and neuronal and glial progenitors reveals selective effects of basic fibroblast growth factor and epidermal growth factor on self-renewal and differentiation
    Dragan Maric
    Laboratory of Neurophysiology, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Neurosci 23:240-51. 2003
  7. pmc Integrating microRNA and mRNA expression profiles of neuronal progenitors to identify regulatory networks underlying the onset of cortical neurogenesis
    Joseph A Nielsen
    Section of Developmental Genetics, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA
    BMC Neurosci 10:98. 2009
  8. pmc Glycogen synthase kinase-3 inhibition induces glioma cell death through c-MYC, nuclear factor-kappaB, and glucose regulation
    Svetlana Kotliarova
    Neuro Oncology Branch, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA
    Cancer Res 68:6643-51. 2008
  9. pmc MicroRNA126 contributes to granulocyte colony-stimulating factor-induced hematopoietic progenitor cell mobilization by reducing the expression of vascular cell adhesion molecule 1
    Ombretta Salvucci
    Laboratory of Cellular Oncology, CCR, NCI, NIH, Bethesda, MD 20892, USA
    Haematologica 97:818-26. 2012
  10. pmc Effect of brain- and tumor-derived connective tissue growth factor on glioma invasion
    Lincoln A Edwards
    Neuro Oncology Branch, National Cancer Institute National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892 1002, USA
    J Natl Cancer Inst 103:1162-78. 2011

Collaborators

Detail Information

Publications53

  1. pmc SUMOylation participates in induction of ischemic tolerance
    Yang ja Lee
    Stroke Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA
    J Neurochem 109:257-67. 2009
    ..These findings suggest that maintenance of a globally elevated SUMO-1 (and maybe SUMO-2/3) conjugation level as revealed by immunoblot assays is a component of ischemic tolerance...
  2. pmc Alpha-synuclein overexpression increases dopamine toxicity in BE2-M17 cells
    Marco Bisaglia
    Department of Biology, University of Padova, 35121 Padova, Italy
    BMC Neurosci 11:41. 2010
    ....
  3. ncbi request reprint Self-renewing and differentiating properties of cortical neural stem cells are selectively regulated by basic fibroblast growth factor (FGF) signaling via specific FGF receptors
    Dragan Maric
    Laboratory of Neurophysiology, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Neurosci 27:1836-52. 2007
    ..These results provide new insights regarding the roles of FGFRs in diversification of NSC properties and initiation of neural lineage-restricted differentiation...
  4. ncbi request reprint GABA expression dominates neuronal lineage progression in the embryonic rat neocortex and facilitates neurite outgrowth via GABA(A) autoreceptor/Cl- channels
    D Maric
    Laboratory of Neurophysiology, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Neurosci 21:2343-60. 2001
    ..These results reveal a morphogenic role for GABA during embryonic neocortical neuron development that involves GABA(A) autoreceptors and L-type Ca(2+) channels...
  5. ncbi request reprint Neural stem cells redefined: a FACS perspective
    Dragan Maric
    Laboratory of Neurophysiology, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
    Mol Neurobiol 30:49-76. 2004
    ..Thus, the strategies presented here provide a framework for more precise studies of NSC and LRP cell biology in the future...
  6. ncbi request reprint Prospective cell sorting of embryonic rat neural stem cells and neuronal and glial progenitors reveals selective effects of basic fibroblast growth factor and epidermal growth factor on self-renewal and differentiation
    Dragan Maric
    Laboratory of Neurophysiology, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Neurosci 23:240-51. 2003
    ....
  7. pmc Integrating microRNA and mRNA expression profiles of neuronal progenitors to identify regulatory networks underlying the onset of cortical neurogenesis
    Joseph A Nielsen
    Section of Developmental Genetics, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA
    BMC Neurosci 10:98. 2009
    ....
  8. pmc Glycogen synthase kinase-3 inhibition induces glioma cell death through c-MYC, nuclear factor-kappaB, and glucose regulation
    Svetlana Kotliarova
    Neuro Oncology Branch, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA
    Cancer Res 68:6643-51. 2008
    ..GSK3 may therefore be an important therapeutic target for gliomas. Future studies will further define the optimal combinations of GSK3 inhibitors and cytotoxic agents for use in gliomas and other cancers...
  9. pmc MicroRNA126 contributes to granulocyte colony-stimulating factor-induced hematopoietic progenitor cell mobilization by reducing the expression of vascular cell adhesion molecule 1
    Ombretta Salvucci
    Laboratory of Cellular Oncology, CCR, NCI, NIH, Bethesda, MD 20892, USA
    Haematologica 97:818-26. 2012
    ..Since hematopoietic stem/progenitor cells represent a minority of all blood cells mobilized by granulocyte colony-stimulating factor, the underlying mechanisms need to be understood in order to develop selective drugs...
  10. pmc Effect of brain- and tumor-derived connective tissue growth factor on glioma invasion
    Lincoln A Edwards
    Neuro Oncology Branch, National Cancer Institute National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892 1002, USA
    J Natl Cancer Inst 103:1162-78. 2011
    ..Connective tissue growth factor (CTGF) has been previously implicated in cancer metastasis and invasion in various tumors. We explored the mechanism of CTGF-mediated glioma cell infiltration and examined potential therapeutic targets...
  11. pmc The transcription factor Gfi1 regulates G-CSF signaling and neutrophil development through the Ras activator RasGRP1
    Maria De La Luz Sierra
    Laboratory of Cellular Oncology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda MD, USA
    Blood 115:3970-9. 2010
    ..These results uncover a previously unknown function of Gfi1 as a regulator of RasGRP1 and link Gfi1 transcriptional control to G-CSF signaling and regulation of granulopoiesis...
  12. pmc Prediction of Associations between microRNAs and Gene Expression in Glioma Biology
    Stefan Wuchty
    Neuro Oncology Branch, National Cancer Institute, National Institutes of Neurological Disorder and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS ONE 6:e14681. 2011
    ....
  13. pmc Circulating CD133+CD34+ progenitor cells inversely correlate with soluble ICAM-1 in early ischemic stroke patients
    Tanya Bogoslovsky
    Stroke Diagnostics and Therapeutics Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892 1401, USA
    J Transl Med 9:145. 2011
    ....
  14. doi request reprint Gliomagenesis arising from Pten- and Ink4a/Arf-deficient neural progenitor cells is mediated by the p53-Fbxw7/Cdc4 pathway, which controls c-Myc
    Hong Sug Kim
    Neuro Oncology Branch, National Cancer Institute, National Institutes of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA
    Cancer Res 72:6065-75. 2012
    ..We propose that p53 mutations contribute to gliomagenesis by both allowing the overexpression of c-Myc through downregulation of Fbxw7 and by protecting against c-Myc-induced apoptosis...
  15. pmc Disruption of downstream MyD88 or TRIF Toll-like receptor signaling does not protect against cerebral ischemia
    Bolanle M Famakin
    Stroke Branch, National Institutes of Neurological Disorders and Stroke, National Institutes of Health, 10 Center Drive, Building 10, Rm 5B06, MSC 1401, Bethesda, MD 20892 1401, USA
    Brain Res 1388:148-56. 2011
    ..4mm(3). These findings show that disruption of MyD88 or TRIF signaling does not confer protection in brain ischemia and suggests the possibility of additional or alternate downstream adaptors during TLR signaling in cerebral ischemia...
  16. pmc Identification of a novel oligodendrocyte cell adhesion protein using gene expression profiling
    Joseph A Nielsen
    Section of Developmental Genetics, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Neurosci 26:9881-91. 2006
    ..Together, our results highlight the usefulness of this discovery-driven experimental strategy to identify genes relevant to oligodendrocyte differentiation and myelination...
  17. pmc GM-CSF/IL-3/IL-5 receptor common beta chain (CD131) expression as a biomarker of antigen-stimulated CD8+ T cells
    Silvia Selleri
    Infectious Disease and Immunogenetics Section IDIS, Department of Transfusion Medicine, Clinical Center, National Institutes of Health, Bethesda, MD, USA
    J Transl Med 6:17. 2008
    ..Whether this secretion affects in an autocrine loop the CTLs themselves is unknown...
  18. doi request reprint Fluorescence-based sorting of neural stem cells and progenitors
    Dragan Maric
    National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA
    Curr Protoc Neurosci . 2005
    ..Thus, the strategy presented here provides a framework for more precise studies of NSC and LRP cell biology in the future, which can be applied to all vertebrates, including humans...
  19. ncbi request reprint Canonical transient receptor potential 1 plays a role in basic fibroblast growth factor (bFGF)/FGF receptor-1-induced Ca2+ entry and embryonic rat neural stem cell proliferation
    Alessandra Fiorio Pla
    Laboratory of Neurophysiology, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Neurosci 25:2687-701. 2005
    ..Together, these results show that TRPC1 contributes to bFGF/FGFR-1-induced Ca2+ influx, which is involved in self-renewal of embryonic rat NSCs...
  20. pmc Unexpected role for granzyme K in CD56bright NK cell-mediated immunoregulation of multiple sclerosis
    Wenzheng Jiang
    Neuroimmunology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
    J Immunol 187:781-90. 2011
    ..Our study describes the important physiological role that GrK plays in immunoregulation of adaptive immunity in humans and indicates that therapeutic exploitation of this pathway is beneficial in controlling autoimmunity...
  21. pmc EphrinB reverse signaling contributes to endothelial and mural cell assembly into vascular structures
    Ombretta Salvucci
    Laboratory of Cellular Oncology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA
    Blood 114:1707-16. 2009
    ..These results reveal a role for EphrinB signaling in orchestrating pericyte/endothelial cell assembly, and suggest that therapeutic targeting of EphrinB may prove useful for disrupting angiogenesis when it contributes to disease...
  22. pmc Epigenetic-mediated dysfunction of the bone morphogenetic protein pathway inhibits differentiation of glioblastoma-initiating cells
    Jeongwu Lee
    Neuro Oncology Branch, National Cancer Institute, National Institute of Neurological Diseases and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
    Cancer Cell 13:69-80. 2008
    ....
  23. pmc Members of the NuRD chromatin remodeling complex interact with AUF1 in developing cortical neurons
    Cheol Lee
    Neuroscience Program, School of Medicine, USUHS, Bethesda, MD 20814, USA
    Cereb Cortex 18:2909-19. 2008
    ..These results suggest that AUF1 is involved in integrating genetic and epigenetic signals during cortical development through recruiting HDAC1 and MTA2 to AT-rich DNA elements...
  24. pmc Kaposi sarcoma herpesvirus promotes endothelial-to-mesenchymal transition through Notch-dependent signaling
    Paola Gasperini
    Laboratory of Cellular Oncology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA
    Cancer Res 72:1157-69. 2012
    ..One important implication of our findings is that therapeutic approaches to disrupt the Notch pathway may offer novel approaches for KS treatment...
  25. pmc Mucosal tolerance to E-selectin promotes the survival of newly generated neuroblasts via regulatory T-cell induction after stroke in spontaneously hypertensive rats
    Satoru Ishibashi
    Stroke Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health NIH, Bethesda, Maryland 20892 4476, USA
    J Cereb Blood Flow Metab 29:606-20. 2009
    ..These studies suggest that E-selectin-specific Tregs can modulate the efficacy of neurogenesis after ischemia and promote repair after brain injury...
  26. doi request reprint Induction of cell death after localization to the host cell mitochondria by the Mycobacterium tuberculosis PE_PGRS33 protein
    Nathalie Cadieux
    Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD, USA
    Microbiology 157:793-804. 2011
    ..Considering the importance of primary necrosis in Mycobacterium tuberculosis dissemination during natural infection, the PE_PGRS33 protein may play a crucial role in the pathogenesis of tuberculosis...
  27. pmc Phosphorylation of p27Kip1 at Thr187 by cyclin-dependent kinase 5 modulates neural stem cell differentiation
    Ya Li Zheng
    Laboratory of Neurochemistry, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892 4130, USA
    Mol Biol Cell 21:3601-14. 2010
    ..Cdk5 phosphorylation of p27(Kip1), a modular molecule, may regulate the progress of neuronal differentiation from cell cycle arrest through differentiation, neurite outgrowth, and migration...
  28. pmc A role for interleukin-2 trans-presentation in dendritic cell-mediated T cell activation in humans, as revealed by daclizumab therapy
    Simone C Wuest
    Neuroimmunology Branch, National Institute of Neurological Disorders and Stroke NINDS, National Institutes of Health NIH, Bethesda, Maryland, USA
    Nat Med 17:604-9. 2011
    ..Our data reveal a previously unknown mechanism for the IL-2 receptor system in DC-mediated activation of T cells...
  29. pmc Induction of IL-17 and nonclassical T-cell activation by HIV-Tat protein
    Tory P Johnson
    Section of Infections of the Nervous System, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 110:13588-93. 2013
    ..This supports the necessity of an anti-Tat therapy in conjunction with ART and identifies multiple targetable pathways to prevent Tat-mediated T-cell activation. ..
  30. pmc In vivo role of alternative splicing and serine phosphorylation of the microphthalmia-associated transcription factor
    Julien Debbache
    Mammalian Development Section, National Institute of Neurological Disorders and Stroke NINDS, National Institutes of Health, Bethesda, MD 20892, USA
    Genetics 191:133-44. 2012
    ..These results underscore, in vivo, the importance of the link between alternative splicing and post-translational modifications and may bear on the recent observation that exon 2B skipping can be found in metastatic melanoma...
  31. doi request reprint The G2385R variant of leucine-rich repeat kinase 2 associated with Parkinson's disease is a partial loss-of-function mutation
    Iakov N Rudenko
    Cell Biology and Gene Expression Section, National Institute on Aging, National Institutes of Health, Bethesda, MD 20892, USA
    Biochem J 446:99-111. 2012
    ..These results may be important in understanding the differing mechanism(s) by which mutations in LRRK2 act and may also have implications for therapeutic strategies for PD...
  32. ncbi request reprint A role for semaphorins and neuropilins in oligodendrocyte guidance
    Rick I Cohen
    Laboratory of Developmental Neurogenetics, The National Institute of Neurological Disorders and Stroke, The National Institutes of Health, Bethesda, Maryland, USA
    J Neurochem 85:1262-78. 2003
    ..Our data support a role for neuropilins and semaphorins in orchestrating the migration patterns of developing oligodendrocytes in the CNS...
  33. pmc MITF and cell proliferation: the role of alternative splice forms
    Keren Bismuth
    Mammalian Development Section, National Institute of Neurological Disorder and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
    Pigment Cell Res 18:349-59. 2005
    ..The results suggest that one or several aminoterminal domains cooperate with the alternatively spliced hexapeptide to render MITF anti-proliferative in a way that does not depend on direct E box binding...
  34. doi request reprint Stromal-derived factor-1[alpha] correlates with circulating endothelial progenitor cells and with acute lesion volume in stroke patients
    Tanya Bogoslovsky
    Center for Neuroscience and Regenerative Medicine, Uniformed Services University of the Health Sciences, National Institute of Nursing Research, National Institutes of Health, 12725 Twinbrook Parkway, Rockville, MD 20852, USA
    Stroke 42:618-25. 2011
    ..We aimed to determine the association between EPC and these GF, and to elucidate a relationship between these GF and stroke severity in acute stroke patients...
  35. pmc Involvement of Akt in preconditioning-induced tolerance to ischemia in PC12 cells
    Joelle A Hillion
    1Stroke Branch, Department of Health and Human Services, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892 4476, USA
    J Cereb Blood Flow Metab 26:1323-31. 2006
    ..This work suggests that in the context of tolerance downregulation of Akt is beneficial...
  36. pmc Long-term, stable differentiation of human embryonic stem cell-derived neural precursors grafted into the adult mammalian neostriatum
    Igor Nasonkin
    Department of Pathology, Division of Neuropathology, Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Stem Cells 27:2414-26. 2009
    ....
  37. pmc Dll4 activation of Notch signaling reduces tumor vascularity and inhibits tumor growth
    Marta Segarra
    Laboratory of Cellular Oncology, Center for Cancer Research, National Cancer Institute NCI, National Institutes of Health NIH, Bethesda, MD 20892, USA
    Blood 112:1904-11. 2008
    ....
  38. pmc Clonal analysis of NRAS activating mutations in KIT-D816V systemic mastocytosis
    Todd M Wilson
    Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, 20892 1881, USA
    Haematologica 96:459-63. 2011
    ..Unlike other mature lineages, mast cell survival is dependent on KIT and the presence of these two activating mutations may have a greater impact on the expansion of this cell compartment and in resultant disease severity...
  39. ncbi request reprint Expression of Notch-1 and its ligands, Delta-like-1 and Jagged-1, is critical for glioma cell survival and proliferation
    Benjamin W Purow
    Neuro Oncology Branch, National Cancer Institute, NIH, Bethesda, MD 20892, USA
    Cancer Res 65:2353-63. 2005
    ..Notch-1 and its ligands may present novel therapeutic targets in the treatment of glioma...
  40. ncbi request reprint Functional properties of ryanodine receptors in hippocampal neurons change during early differentiation in culture
    Manana Sukhareva
    Laboratory of Neurophysiology, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Neurophysiol 88:1077-87. 2002
    ..The mode of activation of L-type voltage-gated Ca(2+) channels with either membrane depolarization or specific pharmacological agents affects the coupled activity of RyRs differently as neurons differentiate processes and networks...
  41. pmc Human herpesvirus-6 entry into the central nervous system through the olfactory pathway
    Erin Harberts
    Viral Immunology Section, National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 108:13734-9. 2011
    ..Collectively, these results support HHV-6 utilization of the olfactory pathway as a route of entry into the CNS...
  42. pmc Regulatory T cells are reduced during anti-CD25 antibody treatment of multiple sclerosis
    Unsong Oh
    Neuroimmunology Branch, National Institute of Neurological Diseases and Stroke NINDS, National Institutes of Health, Bethesda, Maryland, USA
    Arch Neurol 66:471-9. 2009
    ..We examined changes to CD4+CD25+ Treg in patients with MS receiving maintenance anti-CD25 monoclonal antibody treatment to determine the effect of treatment on Treg and, consequently, on immunological tolerance...
  43. pmc Development of an ischemic tolerance model in a PC12 cell line
    Joelle A Hillion
    Stroke Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892 4128, USA
    J Cereb Blood Flow Metab 25:154-62. 2005
    ..This model may be useful to investigate the cellular mechanisms involved in neuronal transient tolerance following ischemia...
  44. pmc Human immunodeficiency virus type 1 infection of human brain-derived progenitor cells
    Diane M P Lawrence
    Laboratory of Molecular Medicine and Neuroscience, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
    J Virol 78:7319-28. 2004
    ..Using this cell culture system of multipotential human brain-derived progenitor cells, we provide evidence that progenitor cells may be a reservoir for HIV-1 in the brains of AIDS patients...
  45. ncbi request reprint The 1p-encoded protein stathmin and resistance of malignant gliomas to nitrosoureas
    Teri T B Ngo
    Surgical and Molecular Neuro oncology Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA
    J Natl Cancer Inst 99:639-52. 2007
    ....
  46. pmc Positive allosteric modulation of TRPV1 as a novel analgesic mechanism
    Evan E Lebovitz
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, NIDCR, NIH, Bldg 49 Rm 1C2049 Convent Dr, Bethesda, MD 20892, USA
    Mol Pain 8:70. 2012
    ..qRT-PCR and immunohistochemistry were performed on dorsal root ganglia to examine changes in gene expression and the cellular specificity of such changes following treatment...
  47. pmc Monocytes form a vascular barrier and participate in vessel repair after brain injury
    John Glod
    Neuro Oncology Branch, National Cancer Institute, and Laboratory of Neurophysiology, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
    Blood 107:940-6. 2006
    ..We also demonstrate that these cells associate with repairing vasculature in areas of brain and skin injury. Our data suggest that CD14+ peripheral blood monocytes participate in the repair of the vascular barrier after brain injury...
  48. ncbi request reprint Helper B cells promote cytotoxic T cell survival and proliferation independently of antigen presentation through CD27/CD70 interactions
    Sara Deola
    Infectious Disease and Immunogenetics Section, Department of Transfusion Medicine, Clinical Center, National Institute of Neurological Disorders and Stroke, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD 20892, USA
    J Immunol 180:1362-72. 2008
    ..This observation provides a mechanistic explanation to previously reported experimental observations suggesting that B cells are required for T cell priming in vivo...
  49. pmc Layer-specific variation of iron content in cerebral cortex as a source of MRI contrast
    Masaki Fukunaga
    Laboratory of Functional and Molecular Imaging, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 107:3834-9. 2010
    ..The results show that iron is distributed over laminae in a pattern that is suggestive of each region's myeloarchitecture and forms the dominant source of the observed MRI contrast...
  50. pmc DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy
    Kelly Jean Thomas
    Laboratory of Neurogenetics, National Institute on Aging, Flow Cytometry Core Facility, National Institutes of Neurological Diseases and Stroke, National Institutes of Health, Bethesda, MD 20982 3707, USA
    Hum Mol Genet 20:40-50. 2011
    ..None of the three proteins complex together using size exclusion chromatography. These data suggest that DJ-1 works in parallel to the PINK1/parkin pathway to maintain mitochondrial function in the presence of an oxidative environment...
  51. pmc In vivo labeling of adult neural progenitors for MRI with micron sized particles of iron oxide: quantification of labeled cell phenotype
    James P Sumner
    Laboratory of Functional and Molecular Imaging, NINDS, NIH, Bethesda, MD 20892, USA
    Neuroimage 44:671-8. 2009
    ..Using MRI to visualize neural progenitor cell behavior in individual animals during plasticity or disease models should be a useful tool, especially in combination with other information that MRI can supply...
  52. ncbi request reprint Detection of virus-specific T cells and CD8+ T-cell epitopes by acquisition of peptide-HLA-GFP complexes: analysis of T-cell phenotype and function in chronic viral infections
    Utano Tomaru
    Neuroimmunology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA
    Nat Med 9:469-76. 2003
    ..This approach will be a powerful tool in understanding the role of antigen-specific T-cell responses in health and disease...
  53. ncbi request reprint Toluene inhibits muscarinic receptor-mediated cytosolic Ca2+ responses in neural precursor cells
    M Wu
    Naval Research Laboratory, Center for Bio Molecular Science and Engineering, Washington, DC 20375, USA
    Neurotoxicology 23:61-8. 2002
    ....