Stefano Marenco

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Investigation of anatomical thalamo-cortical connectivity and FMRI activation in schizophrenia
    Stefano Marenco
    Clinical Brain Disorders Branch, Genes, Cognition, and Psychosis Program, National Institute of Mental Health Intramural Research Program, Bethesda, MD, USA
    Neuropsychopharmacology 37:499-507. 2012
  2. pmc Genetic association of ErbB4 and human cortical GABA levels in vivo
    Stefano Marenco
    Unit for Multimodal Imaging Genetics, Clinical Brain Disorders Branch, Genes Cognition and Psychosis Program, NIH, Bethesda, Maryland 20892, USA
    J Neurosci 31:11628-32. 2011
  3. pmc Regional distribution of measurement error in diffusion tensor imaging
    Stefano Marenco
    Genes, Cognition and Psychosis Program, Clinical Brain Disorders Branch, IRP, NIMH, Bethesda, MD 20892, USA
    Psychiatry Res 147:69-78. 2006
  4. pmc Effect of metabotropic glutamate receptor 3 genotype on N-acetylaspartate measures in the dorsolateral prefrontal cortex
    Stefano Marenco
    Genes and Cognition Program, Clinical Brain Disorders Branch, Intramural Research Program, Bldg 10, Rm 4S235, 10 Center Dr, NIMH, NIH, Bethesda, MD 20892, USA
    Am J Psychiatry 163:740-2. 2006
  5. ncbi request reprint Therapeutic potential of positive AMPA receptor modulators in the treatment of neuropsychiatric disorders
    Stefano Marenco
    Genes, Cognition and Psychosis Program, Clinical Brain Disorders Branch, National Institute of Mental Health, Bethesda, Maryland 20892, USA
    CNS Drugs 20:173-85. 2006
  6. pmc Genetic contributions to white matter architecture revealed by diffusion tensor imaging in Williams syndrome
    Stefano Marenco
    Clinical Brain Disorders Branch, Genes Cognition and Psychosis Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 104:15117-22. 2007
  7. pmc Imaging genetics of structural brain connectivity and neural integrity markers
    Stefano Marenco
    Unit for Multimodal Imaging Genetics, Clinical Brain Disorders Branch, GCAP, IRP, NIMH, 10 Center Drive, Building 10, Room 3C103, Bethesda, MD 20892, USA
    Neuroimage 53:848-56. 2010
  8. pmc Genetic modulation of GABA levels in the anterior cingulate cortex by GAD1 and COMT
    Stefano Marenco
    Clinical Brain Disorders Branch, GCAP, IRP, NIMH, Bethesda, MD 20892, USA
    Neuropsychopharmacology 35:1708-17. 2010
  9. pmc Impact of the brain-derived neurotrophic factor Val66Met polymorphism on levels of hippocampal N-acetyl-aspartate assessed by magnetic resonance spectroscopic imaging at 3 Tesla
    Alexa J Stern
    Clinical Brain Disorders Branch, Genes, Cognition and Psychosis Program, National Institute of Mental Health Intramural Research Program, National Institutes of Health, Bethesda, Maryland 20892, USA
    Biol Psychiatry 64:856-62. 2008
  10. pmc Effects of the BDNF Val66Met polymorphism on white matter microstructure in healthy adults
    Heike Tost
    Clinical Brain Disorders Branch, Genes, Cognition and Psychosis Program, National Institute of Mental Health, Intramural Research Program, NIH, DHHS, Bethesda, MD 20892, USA
    Neuropsychopharmacology 38:525-32. 2013

Detail Information

Publications27

  1. pmc Investigation of anatomical thalamo-cortical connectivity and FMRI activation in schizophrenia
    Stefano Marenco
    Clinical Brain Disorders Branch, Genes, Cognition, and Psychosis Program, National Institute of Mental Health Intramural Research Program, Bethesda, MD, USA
    Neuropsychopharmacology 37:499-507. 2012
    ..These results suggest that thalamocortical connectivity to the LPFC is altered in schizophrenia with functional consequences on working memory processing in LPFC...
  2. pmc Genetic association of ErbB4 and human cortical GABA levels in vivo
    Stefano Marenco
    Unit for Multimodal Imaging Genetics, Clinical Brain Disorders Branch, Genes Cognition and Psychosis Program, NIH, Bethesda, Maryland 20892, USA
    J Neurosci 31:11628-32. 2011
    ..These data establish an association of ErbB4 and GABA in human brain and have implications for understanding the pathogenesis of schizophrenia and other psychiatric disorders...
  3. pmc Regional distribution of measurement error in diffusion tensor imaging
    Stefano Marenco
    Genes, Cognition and Psychosis Program, Clinical Brain Disorders Branch, IRP, NIMH, Bethesda, MD 20892, USA
    Psychiatry Res 147:69-78. 2006
    ..Each one of these measures reveals complementary information that needs to be taken into consideration when performing statistical operations on groups of DT images...
  4. pmc Effect of metabotropic glutamate receptor 3 genotype on N-acetylaspartate measures in the dorsolateral prefrontal cortex
    Stefano Marenco
    Genes and Cognition Program, Clinical Brain Disorders Branch, Intramural Research Program, Bldg 10, Rm 4S235, 10 Center Dr, NIMH, NIH, Bethesda, MD 20892, USA
    Am J Psychiatry 163:740-2. 2006
    ....
  5. ncbi request reprint Therapeutic potential of positive AMPA receptor modulators in the treatment of neuropsychiatric disorders
    Stefano Marenco
    Genes, Cognition and Psychosis Program, Clinical Brain Disorders Branch, National Institute of Mental Health, Bethesda, Maryland 20892, USA
    CNS Drugs 20:173-85. 2006
    ..Substantial questions remain concerning which compounds to use, in what dose, for what condition and for how long...
  6. pmc Genetic contributions to white matter architecture revealed by diffusion tensor imaging in Williams syndrome
    Stefano Marenco
    Clinical Brain Disorders Branch, Genes Cognition and Psychosis Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 104:15117-22. 2007
    ....
  7. pmc Imaging genetics of structural brain connectivity and neural integrity markers
    Stefano Marenco
    Unit for Multimodal Imaging Genetics, Clinical Brain Disorders Branch, GCAP, IRP, NIMH, 10 Center Drive, Building 10, Room 3C103, Bethesda, MD 20892, USA
    Neuroimage 53:848-56. 2010
    ....
  8. pmc Genetic modulation of GABA levels in the anterior cingulate cortex by GAD1 and COMT
    Stefano Marenco
    Clinical Brain Disorders Branch, GCAP, IRP, NIMH, Bethesda, MD 20892, USA
    Neuropsychopharmacology 35:1708-17. 2010
    ..The directionality of the effects, however, is inconsistent with earlier evidence of decreased GABA activity in schizophrenia...
  9. pmc Impact of the brain-derived neurotrophic factor Val66Met polymorphism on levels of hippocampal N-acetyl-aspartate assessed by magnetic resonance spectroscopic imaging at 3 Tesla
    Alexa J Stern
    Clinical Brain Disorders Branch, Genes, Cognition and Psychosis Program, National Institute of Mental Health Intramural Research Program, National Institutes of Health, Bethesda, Maryland 20892, USA
    Biol Psychiatry 64:856-62. 2008
    ....
  10. pmc Effects of the BDNF Val66Met polymorphism on white matter microstructure in healthy adults
    Heike Tost
    Clinical Brain Disorders Branch, Genes, Cognition and Psychosis Program, National Institute of Mental Health, Intramural Research Program, NIH, DHHS, Bethesda, MD 20892, USA
    Neuropsychopharmacology 38:525-32. 2013
    ....
  11. pmc Effect of schizophrenia risk-associated alleles in SREB2 (GPR85) on functional MRI phenotypes in healthy volunteers
    Eugenia Radulescu
    Clinical Brain Disorders Branch, GCAP, IRP, NIMH, Bethesda, MD 20892, USA
    Neuropsychopharmacology 38:341-9. 2013
    ..The findings in females and during the emotional memory paradigm are consistent with modulation by SREB2 of brain circuitries implicated in mood regulation and may be relevant to neuropsychiatric conditions other than schizophrenia...
  12. doi request reprint Reproducibility of prefrontal γ-aminobutyric acid measurements with J-edited spectroscopy
    Matthew Geramita
    Unit for Multimodal Imaging Genetics, Clinical Brain Disorders Branch, National Institute of Mental Health, Bethesda, MD 20892, USA
    NMR Biomed 24:1089-98. 2011
    ..This study validates a reproducible method for the quantification of brain metabolites, and provides information on gray/white matter differences that may be important in the interpretation of results in clinical populations...
  13. pmc No effect of a common allelic variant in the reelin gene on intermediate phenotype measures of brain structure, brain function, and gene expression
    Heike Tost
    Clinical Brain Disorders Branch, Genes, Cognition and Psychosis Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892 1379, USA
    Biol Psychiatry 68:105-7. 2010
    ..In the largest neuroimaging intermediate phenotype study reported so far, we evaluated the effect of rs7341475 on an extended array of different neuroscientific measures...
  14. ncbi request reprint Comparison of cognitive performances during a placebo period and an atypical antipsychotic treatment period in schizophrenia: critical examination of confounds
    Thomas W Weickert
    Clinical Brain Disorders Branch, National Institute of Mental Health NIH, Building 10 Room 4N202, MSC 1379, Bethesda, MD 20892, USA
    Neuropsychopharmacology 28:1491-500. 2003
    ..These findings suggest that relative to placebo withdrawal, atypicals improve cognitive performance in SC. However, this finding may not be specific to atypicals, since analogous studies of typicals have not been performed...
  15. ncbi request reprint Complexity of prefrontal cortical dysfunction in schizophrenia: more than up or down
    Joseph H Callicott
    Clinical Brain Disorders Branch, NIMH NIH, Bldg 10, Rm 4D 20, MSC 1389, Bethesda, MD 20892 1389, USA
    Am J Psychiatry 160:2209-15. 2003
    ..The authors' goal was to explore this phenomenon...
  16. pmc The Williams syndrome chromosome 7q11.23 hemideletion confers hypersocial, anxious personality coupled with altered insula structure and function
    Mbemba Jabbi
    Section on Integrative Neuroimaging, National Institute of Mental Health, Intramural Research Program, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 109:E860-6. 2012
    ....
  17. pmc Functional, structural, and metabolic abnormalities of the hippocampal formation in Williams syndrome
    Andreas Meyer-Lindenberg
    Genes, Cognition, and Psychosis Program, National Institute of Mental Health, NIH, Department of Health and Human Services, Bethesda, MD 20892 1365, USA
    J Clin Invest 115:1888-95. 2005
    ..These data demonstrate abnormalities in HF in WS in agreement with murine models, implicate LIMK1 and CYLN2 in human hippocampal function, and suggest that hippocampal dysfunction may contribute to neurocognitive abnormalities in WS...
  18. pmc An investigation of amino-acid neurotransmitters as potential predictors of clinical improvement to ketamine in depression
    Giacomo Salvadore
    Experimental Therapeutics and Pathophysiology Branch, Division of Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA
    Int J Neuropsychopharmacol 15:1063-72. 2012
    ....
  19. ncbi request reprint In vivo NMR measures of NAA and the neurobiology of schizophrenia
    Stefano Marenco
    Genes, Cognition and Psychosis Program, Division of Intramural Research, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA
    Adv Exp Med Biol 576:227-40; discussion 361-3. 2006
  20. pmc Effects of image distortions originating from susceptibility variations and concomitant fields on diffusion MRI tractography results
    M Okan Irfanoglu
    Program on Pediatric Imaging and Tissue Sciences, NICHD, National Institutes of Health, Bethesda, MD 20892, USA
    Neuroimage 61:275-88. 2012
    ..On the basis of our findings, we recommend adding an EPI distortion correction step to the diffusion MRI processing pipeline if the output is to be used for fiber tractography...
  21. pmc Quantitative measurement of N-acetyl-aspartyl-glutamate at 3 T using TE-averaged PRESS spectroscopy and regularized lineshape deconvolution
    Yan Zhang
    MR Spectroscopy Core Facility, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892 1527, USA
    Magn Reson Med 66:307-13. 2011
    ..11±0.02 for the gray matter voxels (n=8) and 0.18±0.02 for the white matter voxels (n=12)...
  22. ncbi request reprint Preliminary experience with an ampakine (CX516) as a single agent for the treatment of schizophrenia: a case series
    Stefano Marenco
    Intramural Research Program, Clinical Brain Disorders Branch, National Institute of Mental Health, Building 10, Room 4S235, Bethesda, MD 20892, USA
    Schizophr Res 57:221-6. 2002
    ..No clear improvement in psychosis or in cognition was observed over the course of the study. CX516 at the doses tested did not appear to yield dramatic effects as a sole agent, but inference from this study is limited...
  23. ncbi request reprint Correction of frequency and phase variations induced by eddy currents in localized spectroscopy with multiple echo times
    Yan Zhang
    National Institute of Mental Health, Bethesda, Maryland 20892 1527, USA
    Magn Reson Med 58:174-8. 2007
    ..Also, it is demonstrated that the methyl signals of creatine (Cr) at 3.0 ppm and choline (Cho) at 3.2 ppm can be used as internal references in finding frequency and phase disparities between different TEs...
  24. ncbi request reprint Nicotine-induced dopamine release in primates measured with [11C]raclopride PET
    Stefano Marenco
    Clinical Brain Disorders Branch, IRP, NIMH, USA
    Neuropsychopharmacology 29:259-68. 2004
    ....
  25. ncbi request reprint Single-cue delay and trace classical conditioning in schizophrenia
    Stefano Marenco
    Clinical Brain Disorders Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
    Biol Psychiatry 53:390-402. 2003
    ..Classical conditioning provides a means of addressing mechanisms of learning and can therefore help understand the pathophysiology of memory alteration in schizophrenia...
  26. ncbi request reprint Anti-N-methyl-D-aspartate receptor antibodies, cognitive dysfunction, and depression in systemic lupus erythematosus
    Larissa Lapteva
    Sjögren s Syndrome Clinic, National Institute of Dental and Craniofacial Research, NIH, Bethesda, Maryland 20892, USA
    Arthritis Rheum 54:2505-14. 2006
    ..To assess the association of cognitive dysfunction and depression with serum antibodies to N-methyl-D-aspartate (NMDA) receptor (anti-NR2) and analyze clinical and neuroimaging correlates in patients with systemic lupus erythematosus (SLE)...
  27. pmc The evolutionarily conserved G protein-coupled receptor SREB2/GPR85 influences brain size, behavior, and vulnerability to schizophrenia
    Mitsuyuki Matsumoto
    Drug Discovery Research, Astellas Pharma Inc, Tsukuba, Ibaraki 305 8585, Japan
    Proc Natl Acad Sci U S A 105:6133-8. 2008
    ..Our data implicate SREB2 as a potential risk factor for psychiatric disorders and its pathway as a target for psychiatric therapy...