John H Malone

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi Gene expression analysis of the ovary of hybrid females of Xenopus laevis and X. muelleri
    John H Malone
    Department of Biology, The University of Texas Arlington, Box 19498, Arlington, Texas, 76010, USA
    BMC Evol Biol 8:82. 2008
  2. ncbi The genomic 'inner fish' and a regulatory enigma in the vertebrates
    John Malone
    Laboratory of Cellular and Developmental Biology, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD 20892, USA
    J Biol 8:32. 2009
  3. ncbi Patterns of reproductive isolation in toads
    John H Malone
    Department of Biology, The University of Texas at Arlington, Arlington, Texas, United States of America
    PLoS ONE 3:e3900. 2008
  4. ncbi Microarrays, deep sequencing and the true measure of the transcriptome
    John H Malone
    Laboratory of Cellular and Developmental Biology, National Institute of Digestive, Diabetes, and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    BMC Biol 9:34. 2011
  5. ncbi Germline-dependent gene expression in distant non-gonadal somatic tissues of Drosophila
    Michael J Parisi
    Department of Biology, University of Pennsylvania, Philadelphia, PA, USA
    BMC Genomics 11:346. 2010
  6. ncbi Physiological sex predicts hybrid sterility regardless of genotype
    John H Malone
    Department of Biology, University of Texas at Arlington, Box 19498, Arlington, TX 76019, USA
    Science 319:59. 2008
  7. ncbi Sterility and gene expression in hybrid males of Xenopus laevis and X. muelleri
    John H Malone
    Department of Biology, The University of Texas at Arlington, Arlington, Texas, United States of America
    PLoS ONE 2:e781. 2007
  8. ncbi Gene expression polymorphism in Drosophila populations
    Pawel Michalak
    Department of Biology, University of Texas at Arlington, Arlington, TX 76019 0498, USA
    Mol Ecol 16:1179-89. 2007
  9. ncbi Expression in aneuploid Drosophila S2 cells
    Yu Zhang
    Laboratory of Cellular and Developmental Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS Biol 8:e1000320. 2010
  10. ncbi Testis-derived microRNA profiles of African clawed frogs (Xenopus) and their sterile hybrids
    Pawel Michalak
    Department of Biology, University of Texas Arlington, Box 19498, Arlington, TX 76019, USA
    Genomics 91:158-64. 2008

Detail Information

Publications13

  1. ncbi Gene expression analysis of the ovary of hybrid females of Xenopus laevis and X. muelleri
    John H Malone
    Department of Biology, The University of Texas Arlington, Box 19498, Arlington, Texas, 76010, USA
    BMC Evol Biol 8:82. 2008
    ..muelleri). In this work, we examine the gene expression pattern in hybrid females of X. laevis x X. muelleri to determine if this asymmetrical pattern of expression also occurs in hybrid females...
  2. ncbi The genomic 'inner fish' and a regulatory enigma in the vertebrates
    John Malone
    Laboratory of Cellular and Developmental Biology, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD 20892, USA
    J Biol 8:32. 2009
    ..It reveals a core set of genes with similar tissue-expression patterns yet no common regulatory signatures--a gene-expression paradox...
  3. ncbi Patterns of reproductive isolation in toads
    John H Malone
    Department of Biology, The University of Texas at Arlington, Arlington, Texas, United States of America
    PLoS ONE 3:e3900. 2008
    ..We discuss explanations for these patterns, including the role of Haldane's rule in toads and anurans in general, and suggest mechanisms generating patterns of reproductive isolation in anurans...
  4. ncbi Microarrays, deep sequencing and the true measure of the transcriptome
    John H Malone
    Laboratory of Cellular and Developmental Biology, National Institute of Digestive, Diabetes, and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    BMC Biol 9:34. 2011
    ..We conclude that microarrays remain useful and accurate tools for measuring expression levels, and RNA-Seq complements and extends microarray measurements...
  5. ncbi Germline-dependent gene expression in distant non-gonadal somatic tissues of Drosophila
    Michael J Parisi
    Department of Biology, University of Pennsylvania, Philadelphia, PA, USA
    BMC Genomics 11:346. 2010
    ..We know little about the coordinated regulation of gene expression patterns in distant somatic tissues that support the developmental cost of gamete production...
  6. ncbi Physiological sex predicts hybrid sterility regardless of genotype
    John H Malone
    Department of Biology, University of Texas at Arlington, Box 19498, Arlington, TX 76019, USA
    Science 319:59. 2008
    ..Gene expression profiles match these adult phenotypes, and our results demonstrate that faster-male evolution is the most likely mechanism producing hybrid male sterility...
  7. ncbi Sterility and gene expression in hybrid males of Xenopus laevis and X. muelleri
    John H Malone
    Department of Biology, The University of Texas at Arlington, Arlington, Texas, United States of America
    PLoS ONE 2:e781. 2007
    ..muelleri)...
  8. ncbi Gene expression polymorphism in Drosophila populations
    Pawel Michalak
    Department of Biology, University of Texas at Arlington, Arlington, TX 76019 0498, USA
    Mol Ecol 16:1179-89. 2007
    ..melanogaster/races/strains and predicted to be translational-inactive in Cosmopolitan due to a major deletion, was found to be up-regulated in Zimbabwe and down-regulated, but still expressed, in Cosmopolitan...
  9. ncbi Expression in aneuploid Drosophila S2 cells
    Yu Zhang
    Laboratory of Cellular and Developmental Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS Biol 8:e1000320. 2010
    ..Our data indicate that expression dosage compensation dampens the effect of altered DNA copy number genome-wide. For the X chromosome, compensation includes fixed and dose-dependent components...
  10. ncbi Testis-derived microRNA profiles of African clawed frogs (Xenopus) and their sterile hybrids
    Pawel Michalak
    Department of Biology, University of Texas Arlington, Box 19498, Arlington, TX 76019, USA
    Genomics 91:158-64. 2008
    ..A number of candidate differential microRNAs from this study have previously been described as testis-specific in the mouse, suggesting that microRNA structural conservation may be associated with functional retention...
  11. ncbi The sex chromosome that refused to die
    John H Malone
    Laboratory of Cellular and Developmental Biology, National Institute of Diabetes, Digestive, and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    Bioessays 30:409-11. 2008
    ..melanogaster genome.1 These results show that variation on Y has an important influence on the deployment of the genome...
  12. ncbi Mediation of Drosophila autosomal dosage effects and compensation by network interactions
    John H Malone
    Laboratory of Cellular and Developmental Biology, National Institute of Diabetes and Digestive and Kidney Diseases, 50 South Drive, Bethesda, MD 20892, USA
    Genome Biol 13:r28. 2012
    ..While it is often assumed that reducing gene dose by half leads to two-fold less expression, there is partial autosomal dosage compensation in Drosophila, which may be mediated by feedback or buffering in expression networks...
  13. ncbi Sex-biased gene expression in a ZW sex determination system
    John H Malone
    Department of Biology, The University of Texas--Arlington, Box 19498, Arlington, TX 76019, USA
    J Mol Evol 63:427-36. 2006
    ....