Affiliation: National Institutes of Health
- A gastrointestinal stromal tumor in a patient with multiple endocrine neoplasia type 2A and metastatic medullary thyroid cancer to the ovariesRana Malek
Clinical Endocrinology Branch, National Institute of Diabetes and Digestive and Kidney Disease, NIH, Bethesda, MD 20892, USA
Endocr Pract 14:898-901. 2008..To describe the first reported case of a patient with multiple endocrine neoplasia type 2A and a gastrointestinal stromal tumor, as well as the second reported case of metastatic medullary thyroid cancer to the ovary...
- Treatment of type B insulin resistance: a novel approach to reduce insulin receptor autoantibodiesR Malek
Clinical Endocrine Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Building 10 CRC, Room 5 5940, 10 Center Drive, MSC 1453, Bethesda, Maryland 20892, USA
J Clin Endocrinol Metab 95:3641-7. 2010..Blockade of insulin action results in hyperglycemia, hypercatabolism, severe acanthosis nigricans, and hyperandrogenism in women. This rare autoimmune disorder has been treated with various forms of immunosuppression with mixed success...
- The Clinical Center's blood glucose management service: a story in quality integrated careKathryn Feigenbaum
Endocrinology, Nursing, and Patient Care Services, Clinical Center, National Institutes of Health, 10 Center Drive, Bethesda, MD 20892 1530, USA
Diabetes Educ 38:194-206. 2012..This plan of care has been applied across various nursing units that serve patient populations on clinical research trials investigating common and rare diseases and treating patients from the United States and around the world...
- Thyroid hormone induced brown adipose tissue and amelioration of diabetes in a patient with extreme insulin resistanceMonica C Skarulis
Clinical Endocrine Branch, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland 20892 1613, USA
J Clin Endocrinol Metab 95:256-62. 2010..Factors leading to increased BAT are of great interest for its potential role in the treatment of diabetes and obesity...
- Protection from obesity and diabetes by blockade of TGF-β/Smad3 signalingHariom Yadav
Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Clinical Research Center, South Drive and Old Georgetown Road, Bethesda, MD 20892, USA
Cell Metab 14:67-79. 2011..Together, these results demonstrate that TGF-β signaling regulates glucose tolerance and energy homeostasis and suggest that modulation of TGF-β activity might be an effective treatment strategy for obesity and diabetes...