Xuefei Ma


Affiliation: National Institutes of Health
Country: USA


  1. Ma X, Bao J, Adelstein R. Loss of cell adhesion causes hydrocephalus in nonmuscle myosin II-B-ablated and mutated mice. Mol Biol Cell. 2007;18:2305-12 pubmed
    ..These studies show that the scaffolding properties of NM II-B play an important role in cell adhesion, thereby preventing hydrocephalus during mouse brain development. ..
  2. Pecci A, Ma X, Savoia A, Adelstein R. MYH9: Structure, functions and role of non-muscle myosin IIA in human disease. Gene. 2018;664:152-167 pubmed publisher
    ..Moreover, the review focuses on current knowledge about the role of MYH9 variants in human disease. ..
  3. Ma X, Adelstein R. A point mutation in Myh10 causes major defects in heart development and body wall closure. Circ Cardiovasc Genet. 2014;7:257-65 pubmed publisher
    ..Furthermore, impaired NMII-B motor activity inhibits outflow tract myocardialization, leading to mislocalization of the aorta. ..
  4. Ma X, Sung D, Yang Y, Wakabayashi Y, Adelstein R. Nonmuscle myosin IIB regulates epicardial integrity and epicardium-derived mesenchymal cell maturation. J Cell Sci. 2017;130:2696-2706 pubmed publisher
    ..Our findings provide a novel mechanism linking epicardial formation and epicardial function to the activity of the cytoplasmic motor protein NMIIB. ..
  5. Ma X, Jana S, Conti M, Kawamoto S, Claycomb W, Adelstein R. Ablation of nonmuscle myosin II-B and II-C reveals a role for nonmuscle myosin II in cardiac myocyte karyokinesis. Mol Biol Cell. 2010;21:3952-62 pubmed publisher
    ..Our study shows that NM II is involved in regulating cardiac myocyte karyokinesis by affecting microtubule dynamics. ..