Research Topics
| Hong Tao MaSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
The cellular and molecular basis of store-operated calcium entryKartik Venkatachalam
Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
Nat Cell Biol 4:E263-72. 2002..Here we review new insights into the exchange of signals between the endoplasmic reticulum (ER) and plasma membrane that result in activation of calcium entry channels mediating crucial long-term calcium signals...
Canonical transient receptor potential 5 channel in conjunction with Orai1 and STIM1 allows Sr2+ entry, optimal influx of Ca2+, and degranulation in a rat mast cell lineHong Tao Ma
Laboratory of Molecular Immunology, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA
J Immunol 180:2233-9. 2008..These and other observations suggest that the Sr(2+)-permeable TRPC5 associates with STIM1 and Orai1 in a stoichiometric manner to enhance entry of Ca(2+) to generate a signal for degranulation...
Synergistic activation of phospholipases Cgamma and Cbeta: a novel mechanism for PI3K-independent enhancement of FcepsilonRI-induced mast cell mediator releaseHye Sun Kuehn
Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 10 Center Drive MSC 1881, Bethesda, MD 20892 1881, USA
Cell Signal 20:625-36. 2008..These responses were critical for the promotion of degranulation. This is the first report of synergistic activation between PLCgamma and PLCbeta that permits reinforcement of signals for degranulation in mast cells...
Protein kinase C beta and delta isoenzymes mediate cholesterol accumulation in PMA-activated macrophagesHong Tao Ma
Section of Experimental Atherosclerosis, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892 1422, USA
Biochem Biophys Res Commun 349:214-20. 2006..Thus, our findings show that beta and some other PKC isoenzyme, most likely delta, mediate cholesterol accumulation when macropinocytosis of LDL is stimulated in PMA-activated human monocyte-derived macrophages...
Regulation of Ca2+ signaling with particular focus on mast cellsHong Tao Ma
Laboratory of Molecular Immunology, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA
Crit Rev Immunol 29:155-86. 2009....
Regulators of Ca(2+) signaling in mast cells: potential targets for treatment of mast cell-related diseases?Hong Tao Ma
Laboratory of Molecular Immunology, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA
Adv Exp Med Biol 716:62-90. 2011....
Modification of store-operated channel coupling and inositol trisphosphate receptor function by 2-aminoethoxydiphenyl borate in DT40 lymphocytesHong-Tao Ma
Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, 108 North Greene Street, Baltimore, MD 21201, USA
J Biol Chem 277:6915-22. 2002....
Modification of phospholipase C-gamma-induced Ca2+ signal generation by 2-aminoethoxydiphenyl borateHong-Tao Ma
Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, 108 North Greene Street, Baltimore, MD 21201, USA
Biochem J 376:667-76. 2003..The results suggest that 2-APB activates Ca(2+) signals in lymphocytes by initiating and enhancing coupling between components of the BCR-PLC-gamma2 complex and both Ca(2+)-entry and Ca(2+)-release channels...
[Screening of a sub-clone of human breast cancer cells with high metastasis potential]Li Hong Ye
College of Life Sciences, Nankai University, Tianjin 300071, China
Zhonghua Yi Xue Za Zhi 86:61-5. 2006..To screen a sub-clone of human breast cancer cell of the MCF-7 line with high metastasis potential...
