Shannon M Lynch

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Cigarette smoking and pancreatic cancer: a pooled analysis from the pancreatic cancer cohort consortium
    Shannon M Lynch
    National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland, USA
    Am J Epidemiol 170:403-13. 2009
  2. ncbi request reprint Solution structure of the mature HIV-1 protease monomer: insight into the tertiary fold and stability of a precursor
    Rieko Ishima
    Molecular Structural Biology Unit, NIDCR, National Institutes of Health, Bethesda, Maryland 20892 4307, USA
    J Biol Chem 278:43311-9. 2003
  3. ncbi request reprint Revisiting monomeric HIV-1 protease. Characterization and redesign for improved properties
    John M Louis
    Laboratory of Chemical Physics, National Institute Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Biol Chem 278:6085-92. 2003
  4. pmc Mitochondrial DNA copy number and pancreatic cancer in the alpha-tocopherol beta-carotene cancer prevention study
    Shannon M Lynch
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Rockville, MD 20852, USA
    Cancer Prev Res (Phila) 4:1912-9. 2011
  5. pmc Cancer incidence among pesticide applicators exposed to cyanazine in the agricultural health study
    Shannon M Lynch
    Clinical and Genetic Epidemiology Research Branch, Epidemiology and Genetics Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, Maryland 20892, USA
    Environ Health Perspect 114:1248-52. 2006
  6. pmc Cancer incidence among pesticide applicators exposed to butylate in the Agricultural Health Study (AHS)
    Shannon M Lynch
    Epidemiology and Genetics Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852, USA
    Environ Res 109:860-8. 2009

Detail Information

Publications6

  1. pmc Cigarette smoking and pancreatic cancer: a pooled analysis from the pancreatic cancer cohort consortium
    Shannon M Lynch
    National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland, USA
    Am J Epidemiol 170:403-13. 2009
    ..This finding and the decline in risk after smoking cessation suggest that smoking has a late-stage effect on pancreatic carcinogenesis...
  2. ncbi request reprint Solution structure of the mature HIV-1 protease monomer: insight into the tertiary fold and stability of a precursor
    Rieko Ishima
    Molecular Structural Biology Unit, NIDCR, National Institutes of Health, Bethesda, Maryland 20892 4307, USA
    J Biol Chem 278:43311-9. 2003
    ..Knowledge of the protease monomer structure and critical features of its dimerization may aid in the screening and design of compounds that target the protease prior to its maturation from the Gag-Pol precursor...
  3. ncbi request reprint Revisiting monomeric HIV-1 protease. Characterization and redesign for improved properties
    John M Louis
    Laboratory of Chemical Physics, National Institute Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Biol Chem 278:6085-92. 2003
    ..This extends the target area of current inhibitors, all of which bind across the active site formed by both subunits in the active dimer...
  4. pmc Mitochondrial DNA copy number and pancreatic cancer in the alpha-tocopherol beta-carotene cancer prevention study
    Shannon M Lynch
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Rockville, MD 20852, USA
    Cancer Prev Res (Phila) 4:1912-9. 2011
    ..14, 95% CI = 0.53-2.45, continuous OR = 1.05, 95% CI = 0.93-1.18). Our results support the hypothesis that mtDNA copy number is associated with pancreatic cancer and could possibly serve as a biomarker for pancreatic cancer development...
  5. pmc Cancer incidence among pesticide applicators exposed to cyanazine in the agricultural health study
    Shannon M Lynch
    Clinical and Genetic Epidemiology Research Branch, Epidemiology and Genetics Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, Maryland 20892, USA
    Environ Health Perspect 114:1248-52. 2006
    ..We evaluated cancer incidence in cyanazine-exposed pesticide applicators among the 57,311 licensed pesticide applicators in the Agricultural Health Study (AHS)...
  6. pmc Cancer incidence among pesticide applicators exposed to butylate in the Agricultural Health Study (AHS)
    Shannon M Lynch
    Epidemiology and Genetics Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852, USA
    Environ Res 109:860-8. 2009
    ..27, 95% CI=1.18-4.37; NHL: RR(LD)=3.44, 95% CI=1.29-9.21). Our analysis did not find meaningful associations for other cancers analyzed. Further study is warranted for AL, NHL and prostate cancers...