Enrico Lugli

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Superior T memory stem cell persistence supports long-lived T cell memory
    Enrico Lugli
    Immunotechnology Section, Vaccine Research Center, NIAID, NIH, 40, Convent Dr, Bethesda, Maryland 20892, USA
    J Clin Invest 123:594-9. 2013
  2. doi request reprint Identification, isolation and in vitro expansion of human and nonhuman primate T stem cell memory cells
    Enrico Lugli
    Immunotechnology Section, Vaccine Research Center VRC, National Institute of Allergy and Infectious Diseases, US National Institutes of Health NIH, Bethesda, MD, USA
    Nat Protoc 8:33-42. 2013
  3. pmc Data analysis in flow cytometry: the future just started
    Enrico Lugli
    Immuno Technology Section, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland 20892, USA
    Cytometry A 77:705-13. 2010
  4. pmc Safety (toxicity), pharmacokinetics, immunogenicity, and impact on elements of the normal immune system of recombinant human IL-15 in rhesus macaques
    Thomas A Waldmann
    Center for Cancer Research, National Cancer Institute, Frederick, MD, USA
    Blood 117:4787-95. 2011
  5. pmc Transient and persistent effects of IL-15 on lymphocyte homeostasis in nonhuman primates
    Enrico Lugli
    Immunotechnology Section, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health NIH, Bethesda, MD, USA
    Blood 116:3238-48. 2010
  6. pmc A human memory T cell subset with stem cell-like properties
    Luca Gattinoni
    Center for Cancer Research, National Cancer Institute, US National Institutes of Health NIH, Bethesda, Maryland, USA
    Nat Med 17:1290-7. 2011
  7. pmc IL-15 delays suppression and fails to promote immune reconstitution in virally suppressed chronically SIV-infected macaques
    Enrico Lugli
    Immunotechnology Section, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA
    Blood 118:2520-9. 2011

Detail Information

Publications7

  1. pmc Superior T memory stem cell persistence supports long-lived T cell memory
    Enrico Lugli
    Immunotechnology Section, Vaccine Research Center, NIAID, NIH, 40, Convent Dr, Bethesda, Maryland 20892, USA
    J Clin Invest 123:594-9. 2013
    ..Thus, one mechanism for maintenance of long-term T cell memory derives from the unique homeostatic properties of TSCM cells. Vaccination strategies designed to elicit durable cellular immunity should target the generation of TSCM cells...
  2. doi request reprint Identification, isolation and in vitro expansion of human and nonhuman primate T stem cell memory cells
    Enrico Lugli
    Immunotechnology Section, Vaccine Research Center VRC, National Institute of Allergy and Infectious Diseases, US National Institutes of Health NIH, Bethesda, MD, USA
    Nat Protoc 8:33-42. 2013
    ..We also indicate multiple strategies for their efficient expansion in vitro at consistent numbers for functional characterization or adoptive transfer experiments...
  3. pmc Data analysis in flow cytometry: the future just started
    Enrico Lugli
    Immuno Technology Section, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland 20892, USA
    Cytometry A 77:705-13. 2010
    ..In this article, we will review the new developments concerning the use of bioinformatics for polychromatic flow cytometry and propose what should be done to unravel the enormous heterogeneity of the cells we interrogate each day...
  4. pmc Safety (toxicity), pharmacokinetics, immunogenicity, and impact on elements of the normal immune system of recombinant human IL-15 in rhesus macaques
    Thomas A Waldmann
    Center for Cancer Research, National Cancer Institute, Frederick, MD, USA
    Blood 117:4787-95. 2011
    ....
  5. pmc Transient and persistent effects of IL-15 on lymphocyte homeostasis in nonhuman primates
    Enrico Lugli
    Immunotechnology Section, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health NIH, Bethesda, MD, USA
    Blood 116:3238-48. 2010
    ..Thus, IL-15 generates a dramatic expansion of short-lived memory CD8 T cells and NK cells in immunocompetent macaques and has long-term effects on the balance of CD4(+) and CD8(+) T cells...
  6. pmc A human memory T cell subset with stem cell-like properties
    Luca Gattinoni
    Center for Cancer Research, National Cancer Institute, US National Institutes of Health NIH, Bethesda, Maryland, USA
    Nat Med 17:1290-7. 2011
    ..The identification of a human stem cell-like memory T cell population is of direct relevance to the design of vaccines and T cell therapies...
  7. pmc IL-15 delays suppression and fails to promote immune reconstitution in virally suppressed chronically SIV-infected macaques
    Enrico Lugli
    Immunotechnology Section, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA
    Blood 118:2520-9. 2011
    ....