Jay H Lubin

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Risk of lung cancer and residential radon in China: pooled results of two studies
    Jay H Lubin
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20892, USA
    Int J Cancer 109:132-7. 2004
  2. ncbi request reprint Cancer incidence among pesticide applicators exposed to metolachlor in the Agricultural Health Study
    Jennifer A Rusiecki
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20892, USA
    Int J Cancer 118:3118-23. 2006
  3. ncbi request reprint Cancer incidence among male pesticide applicators in the Agricultural Health Study cohort exposed to diazinon
    Laura E Beane Freeman
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20892, USA
    Am J Epidemiol 162:1070-9. 2005
  4. pmc Atrazine and cancer incidence among pesticide applicators in the agricultural health study (1994-2007)
    Laura E Beane Freeman
    Division of Cancer, Epidemiology, and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
    Environ Health Perspect 119:1253-9. 2011
  5. pmc Methyl bromide exposure and cancer risk in the Agricultural Health Study
    Kathryn Hughes Barry
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Blvd, Bethesda, MD 20892 7240, USA
    Cancer Causes Control 23:807-18. 2012
  6. pmc Genetic variation in nucleotide excision repair pathway genes, pesticide exposure and prostate cancer risk
    Kathryn Hughes Barry
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD 20892 7240, USA
    Carcinogenesis 33:331-7. 2012
  7. pmc Genetic variation in base excision repair pathway genes, pesticide exposure, and prostate cancer risk
    Kathryn Hughes Barry
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland 20892 7240, USA
    Environ Health Perspect 119:1726-32. 2011
  8. ncbi request reprint Cancer incidence among pesticide applicators exposed to chlorpyrifos in the Agricultural Health Study
    Won Jin Lee
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Rockville, MD 20852, USA
    J Natl Cancer Inst 96:1781-9. 2004
  9. ncbi request reprint [Influence of menstrual and reproductive factors on the risk of lung cancer]
    Alina V Brenner
    Radiation Epidemiology Branch, Divison of Cancer Epidemiology and Genetics, National Cancer Institute, USA
    Zhonghua Liu Xing Bing Xue Za Zhi 25:590-3. 2004
  10. pmc The Diesel Exhaust in Miners study: a nested case-control study of lung cancer and diesel exhaust
    Debra T Silverman
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20816, USA
    J Natl Cancer Inst 104:855-68. 2012

Detail Information

Publications85

  1. ncbi request reprint Risk of lung cancer and residential radon in China: pooled results of two studies
    Jay H Lubin
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20892, USA
    Int J Cancer 109:132-7. 2004
    ....
  2. ncbi request reprint Cancer incidence among pesticide applicators exposed to metolachlor in the Agricultural Health Study
    Jennifer A Rusiecki
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20892, USA
    Int J Cancer 118:3118-23. 2006
    ....
  3. ncbi request reprint Cancer incidence among male pesticide applicators in the Agricultural Health Study cohort exposed to diazinon
    Laura E Beane Freeman
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20892, USA
    Am J Epidemiol 162:1070-9. 2005
    ..Because these results were based on small numbers, additional analyses are necessary as more cases accrue to clarify whether diazinon is associated with cancer risk in humans...
  4. pmc Atrazine and cancer incidence among pesticide applicators in the agricultural health study (1994-2007)
    Laura E Beane Freeman
    Division of Cancer, Epidemiology, and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
    Environ Health Perspect 119:1253-9. 2011
    ..Atrazine is a triazine herbicide used widely in the United States. Although it is an animal carcinogen, the mechanism in rodents does not appear to operate in humans. Few epidemiologic studies have provided evidence for an association...
  5. pmc Methyl bromide exposure and cancer risk in the Agricultural Health Study
    Kathryn Hughes Barry
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Blvd, Bethesda, MD 20892 7240, USA
    Cancer Causes Control 23:807-18. 2012
    ..Although many countries have reduced methyl bromide use because of its ozone depleting properties, some uses remain in the United States and other countries, warranting further investigation of human health effects...
  6. pmc Genetic variation in nucleotide excision repair pathway genes, pesticide exposure and prostate cancer risk
    Kathryn Hughes Barry
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD 20892 7240, USA
    Carcinogenesis 33:331-7. 2012
    ..09). In contrast, we did not observe associations among men with other genotypes at these loci. While requiring replication, our findings suggest a role for NER genetic variation in pesticide-associated prostate cancer risk...
  7. pmc Genetic variation in base excision repair pathway genes, pesticide exposure, and prostate cancer risk
    Kathryn Hughes Barry
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland 20892 7240, USA
    Environ Health Perspect 119:1726-32. 2011
    ..Previous research indicates increased prostate cancer risk for pesticide applicators and pesticide manufacturing workers. Although underlying mechanisms are unknown, evidence suggests a role of oxidative DNA damage...
  8. ncbi request reprint Cancer incidence among pesticide applicators exposed to chlorpyrifos in the Agricultural Health Study
    Won Jin Lee
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Rockville, MD 20852, USA
    J Natl Cancer Inst 96:1781-9. 2004
    ..We evaluated the incidence of cancer among pesticide applicators exposed to chlorpyrifos in the Agricultural Health Study, a prospective cohort study of licensed pesticide applicators in Iowa and North Carolina...
  9. ncbi request reprint [Influence of menstrual and reproductive factors on the risk of lung cancer]
    Alina V Brenner
    Radiation Epidemiology Branch, Divison of Cancer Epidemiology and Genetics, National Cancer Institute, USA
    Zhonghua Liu Xing Bing Xue Za Zhi 25:590-3. 2004
    ..The study is to identify the influence of female hormones on risk of lung cancer...
  10. pmc The Diesel Exhaust in Miners study: a nested case-control study of lung cancer and diesel exhaust
    Debra T Silverman
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20816, USA
    J Natl Cancer Inst 104:855-68. 2012
    ..Our purpose was to evaluate the relationship between quantitative estimates of exposure to diesel exhaust and lung cancer mortality after adjustment for smoking and other potential confounders...
  11. ncbi request reprint Cigarette smoking and cancer risk: modeling total exposure and intensity
    Jay H Lubin
    Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
    Am J Epidemiol 166:479-89. 2007
    ..The intensity effects were statistically homogeneous, indicating that after accounting for risk from total pack-years, intensity patterns were comparable across the diverse cancer sites...
  12. pmc An examination of male and female odds ratios by BMI, cigarette smoking, and alcohol consumption for cancers of the oral cavity, pharynx, and larynx in pooled data from 15 case-control studies
    Jay H Lubin
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Rockville, MD 20852, USA
    Cancer Causes Control 22:1217-31. 2011
    ....
  13. pmc The Diesel Exhaust in Miners Study: IV. Estimating historical exposures to diesel exhaust in underground non-metal mining facilities
    Roel Vermeulen
    Division of Cancer Epidemiology and Genetics, US National Cancer Institute, Bethesda, MD 20892, USA
    Ann Occup Hyg 54:774-88. 2010
    ..These REC exposure estimates were in a plausible range and were used in the investigation of exposure-response relationships in epidemiologic analyses...
  14. pmc Chronic obstructive pulmonary disease and altered risk of lung cancer in a population-based case-control study
    Jill Koshiol
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America
    PLoS ONE 4:e7380. 2009
    ..Chronic obstructive pulmonary disease (COPD) has been consistently associated with increased risk of lung cancer. However, previous studies have had limited ability to determine whether the association is due to smoking...
  15. pmc Pendimethalin exposure and cancer incidence among pesticide applicators
    Lifang Hou
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852, USA
    Epidemiology 17:302-7. 2006
    ..We evaluated the incidence of cancer in relation to reported pendimethelin use among pesticide applicators in the Agricultural Health Study, a prospective cohort of licensed pesticide applicators in Iowa and North Carolina...
  16. pmc Risk of total and aggressive prostate cancer and pesticide use in the Agricultural Health Study
    Stella Koutros
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, EPS 8115, MSC 7240, Rockville, MD 20852, USA
    Am J Epidemiol 177:59-74. 2013
    ..Furthermore, this is the first time specific pesticides are implicated as risk factors for aggressive prostate cancer...
  17. pmc Are women who smoke at higher risk for lung cancer than men who smoke?
    Sara De Matteis
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
    Am J Epidemiol 177:601-12. 2013
    ..g., tobacco type, inhalation depth, Fagerström-assessed nicotine dependence). These findings do not support a higher female susceptibility to tobacco-related lung cancer...
  18. ncbi request reprint Cigarette smoking and lung cancer: modeling effect modification of total exposure and intensity
    Jay H Lubin
    Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20852, USA
    Epidemiology 18:639-48. 2007
    ..Above 20 cigarettes per day, there is an "inverse-exposure-rate" effect, ie, the excess odds ratio per pack-year for higher intensity smokers is smaller than for lower-intensity smokers...
  19. pmc Impact of pesticide exposure misclassification on estimates of relative risks in the Agricultural Health Study
    Aaron Blair
    National Cancer Institute, Executive Plaza South, Room 8008, Bethesda, MD 20892, USA
    Occup Environ Med 68:537-41. 2011
    ..We evaluate the impact of occupational pesticide exposure misclassification on relative risks using data from the cohort and the AHS Pesticide Exposure Study (AHS/PES)...
  20. ncbi request reprint Cancer incidence among pesticide applicators exposed to atrazine in the Agricultural Health Study
    Jennifer A Rusiecki
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20892 7240, USA
    J Natl Cancer Inst 96:1375-82. 2004
    ..We evaluated cancer incidence in atrazine-exposed pesticide applicators among 53,943 participants in the Agricultural Health Study, a prospective cohort study of licensed pesticide applicators in Iowa and North Carolina...
  21. pmc An update of cancer incidence in the Agricultural Health Study
    Stella Koutros
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health DHHS, 6120 Executive Blvd, Rockville, MD 20852, USA
    J Occup Environ Med 52:1098-105. 2010
    ..Our objective is to reevaluate cancer incidence among Agricultural Health Study participants...
  22. pmc Pesticide exposure and inherited variants in vitamin d pathway genes in relation to prostate cancer
    Sara Karami
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, MD 20852, USA
    Cancer Epidemiol Biomarkers Prev 22:1557-66. 2013
    ..Certain pesticides have been shown to deregulate vitamin D's anticarcinogenic properties. We hypothesize that certain pesticides may be linked to prostate cancer via an interaction with vitamin D genetic variants...
  23. ncbi request reprint Cancer and other causes of mortality among radiologic technologists in the United States
    Aparna K Mohan
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7244, USA
    Int J Cancer 103:259-67. 2003
    ....
  24. pmc Mortality from lymphohematopoietic malignancies among workers in formaldehyde industries: the National Cancer Institute Cohort
    Laura E Beane Freeman
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD 20892, USA
    J Natl Cancer Inst 101:751-61. 2009
    ....
  25. doi request reprint Mortality from solid tumors among workers in formaldehyde industries: an update of the NCI cohort
    Laura E Beane Freeman
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
    Am J Ind Med 56:1015-26. 2013
    ..Formaldehyde, a widely used chemical, is considered a human carcinogen...
  26. pmc An updated algorithm for estimation of pesticide exposure intensity in the agricultural health study
    Joseph Coble
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20892, USA
    Int J Environ Res Public Health 8:4608-22. 2011
    ....
  27. pmc Pesticide use modifies the association between genetic variants on chromosome 8q24 and prostate cancer
    Stella Koutros
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, Maryland 20852, USA
    Cancer Res 70:9224-33. 2010
    ..This is the first report of effect modification between 8q24 and an environmental exposure on prostate cancer risk...
  28. ncbi request reprint Lung cancer and indoor exposure to coal and biomass in rural China
    Ruth A Kleinerman
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, EPS 7044, MSC 7238, Bethesda, MD 20892, USA
    J Occup Environ Med 44:338-44. 2002
    ..The risk for lung cancer increased relative to the percentage of time that coal was used over the past 30 years (P = 0.02). Our findings suggest that coal may contribute to the risk of lung cancer in this rural area of China...
  29. ncbi request reprint Pesticide use and breast cancer risk among farmers' wives in the agricultural health study
    Lawrence S Engel
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Am J Epidemiol 161:121-35. 2005
    ..Further follow-up of this cohort should help clarify the relation between pesticide exposure and breast cancer risk...
  30. pmc Using multiple imputation to assign pesticide use for non-responders in the follow-up questionnaire in the Agricultural Health Study
    Sonya L Heltshe
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA
    J Expo Sci Environ Epidemiol 22:409-16. 2012
    ..When appropriately implemented, multiple imputation can reduce bias and increase precision and can be more valid than other missing data approaches...
  31. pmc Dietary quercetin, quercetin-gene interaction, metabolic gene expression in lung tissue and lung cancer risk
    Tram Kim Lam
    Cancer Prevention Fellowship Program, Office of Preventive Oncology, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    Carcinogenesis 31:634-42. 2010
    ..Our findings suggest an interplay between quercetin intake, tobacco smoking, and lung cancer risk. Further research on this relationship is warranted...
  32. ncbi request reprint Factor analysis of pesticide use patterns among pesticide applicators in the Agricultural Health Study
    Claudine Samanic
    National Cancer Institute, Division of Cancer Epidemiology and Genetics, Bethesda, Maryland, USA
    J Expo Anal Environ Epidemiol 15:225-33. 2005
    ..This heterogeneity in exposure patterns may be used to guide etiologic studies of health effects of farmers and other groups exposed to pesticides...
  33. ncbi request reprint Endometrial carcinoma risks among menopausal estrogen plus progestin and unopposed estrogen users in a cohort of postmenopausal women
    James V Lacey
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland, USA
    Cancer Epidemiol Biomarkers Prev 14:1724-31. 2005
    ..However, endometrial carcinoma risks among estrogen plus progestin users and among former unopposed estrogen users are not firmly established...
  34. ncbi request reprint Cancer incidence among pesticide applicators exposed to alachlor in the Agricultural Health Study
    Won Jin Lee
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852, USA
    Am J Epidemiol 159:373-80. 2004
    ..Our findings suggest a possible association between alachlor application and incidence of lymphohematopoietic cancers among applicators in the Agricultural Health Study...
  35. ncbi request reprint Mortality from solid cancers among workers in formaldehyde industries
    Michael Hauptmann
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Bethesda, MD 20892, USA
    Am J Epidemiol 159:1117-30. 2004
    ..In this cohort of formaldehyde-industry workers, some evidence was found of an exposure-response relation with mortality from nasopharyngeal cancer (based on small numbers) but not for cancers of the pancreas, brain, lung, or prostate...
  36. pmc GSTM1 and GSTT1 copy numbers and mRNA expression in lung cancer
    Melissa Rotunno
    Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892 7248, USA
    Mol Carcinog 51:E142-50. 2012
    ..A protective effect of the same mutations may be operative in never-smokers and women, possibly because of reduced activity of other genotoxic chemicals...
  37. pmc Body mass index, cigarette smoking, and alcohol consumption and cancers of the oral cavity, pharynx, and larynx: modeling odds ratios in pooled case-control data
    Jay H Lubin
    Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Rockville, MD 20852, USA
    Am J Epidemiol 171:1250-61. 2010
    ....
  38. pmc Xenobiotic-metabolizing gene variants, pesticide use, and the risk of prostate cancer
    Stella Koutros
    Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20852, USA
    Pharmacogenet Genomics 21:615-23. 2011
    ..To explore associations with prostate cancer and farming, it is important to investigate the relationship between pesticide use and single nucleotide polymorphisms (SNPs) in xenobiotic metabolic enzyme (XME) genes...
  39. pmc Mood disorders and risk of lung cancer in the EAGLE case-control study and in the U.S. Veterans Affairs inpatient cohort
    David E Capo-Ramos
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS ONE 7:e42945. 2012
    ..Mood disorders may affect lung cancer risk. We evaluated this hypothesis in two large studies...
  40. pmc Phase I metabolic genes and risk of lung cancer: multiple polymorphisms and mRNA expression
    Melissa Rotunno
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS ONE 4:e5652. 2009
    ..Our findings emphasize the necessity of post-GWAS fine mapping and SNP functional assessment to further elucidate cancer risk associations...
  41. ncbi request reprint Methodological issues regarding confounding and exposure misclassification in epidemiological studies of occupational exposures
    Aaron Blair
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, Maryland 20892, USA
    Am J Ind Med 50:199-207. 2007
    ..Although it is important to consider the potential for limitations of epidemiologic investigations, judgment regarding their importance should be based on their actual likelihood of occurrence...
  42. ncbi request reprint Weight, height, and body mass index and risk for ovarian cancer in a cohort study
    James V Lacey
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville 20852 7234, MD
    Ann Epidemiol 16:869-76. 2006
    ..Reported associations between ovarian cancer and body size are inconsistent. We assessed ovarian cancer and anthropometry in the Breast Cancer Detection Demonstration Project Follow-Up Study...
  43. ncbi request reprint Menstrual and reproductive factors and risk of lung cancer among Chinese women, Eastern Gansu Province, 1994-1998
    Alina V Brenner
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Rockville, EPS, Bethesda, MD 20892, USA
    J Epidemiol 13:22-8. 2003
    ..Odds ratios were lower for later ages at menarche (trend, P = 0.015) and later ages at menopause (trend, P = 0.074). Despite limitations, these findings suggest a possible role of hormones in the etiology of lung cancer in females...
  44. ncbi request reprint Cancer incidence in the agricultural health study
    Michael C R Alavanja
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20892, USA
    Scand J Work Environ Health 31:39-45; discussion 5-7. 2005
    ..This large, prospective cohort study of private applicators, commercial applicators, and spouses of farmer applicators was undertaken to ascertain the etiology of cancers elevated in agriculture...
  45. pmc The importance of exposure rate on odds ratios by cigarette smoking and alcohol consumption for esophageal adenocarcinoma and squamous cell carcinoma in the Barrett's Esophagus and Esophageal Adenocarcinoma Consortium
    Jay H Lubin
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH DHHS, Bethesda, MD 20892, USA
    Cancer Epidemiol 36:306-16. 2012
    ..e., the impact on the OR for a fixed total exposure of high exposure rate for short duration compared with low exposure rate for long duration...
  46. ncbi request reprint Radon, secondhand smoke, glutathione-S-transferase M1 and lung cancer among women
    Matthew R Bonner
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Rockville, MD, USA
    Int J Cancer 119:1462-7. 2006
    ..Additionally, these findings support the hypothesis that radon and SHS promote neoplasia through shared elements of a common pathway...
  47. ncbi request reprint Cigarette smoking and lung cancer: modeling total exposure and intensity
    Jay H Lubin
    Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Rockville, MD 20852, USA
    Cancer Epidemiol Biomarkers Prev 15:517-23. 2006
    ..e., smoking at a lower intensity for longer duration is more deleterious than smoking at a higher intensity for shorter duration)...
  48. ncbi request reprint Mortality from lymphohematopoietic malignancies among workers in formaldehyde industries
    Michael Hauptmann
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    J Natl Cancer Inst 95:1615-23. 2003
    ..We extended follow-up of a cohort of industrial workers to evaluate the association between formaldehyde exposure and lymphohematopoietic cancers...
  49. pmc Lower risk of lung cancer after multiple pneumonia diagnoses
    Jill Koshiol
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, MSC 7248, Bethesda, MD 20892 7248, USA
    Cancer Epidemiol Biomarkers Prev 19:716-21. 2010
    ..Although pneumonia has been suggested as a risk factor for lung cancer, previous studies have not evaluated the influence of number of pneumonia diagnoses in relation to lung cancer risk...
  50. pmc Menstrual and reproductive factors and gastric cancer risk in a large prospective study of women
    Neal D Freedman
    Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
    Gut 56:1671-7. 2007
    ..Gastric cancer incidence rates are consistently lower in women than men in both high and low-risk regions worldwide. Sex hormones, such as progesterone and estrogen, may protect women against gastric cancer...
  51. ncbi request reprint Mortality rates among augmentation mammoplasty patients: an update
    Louise A Brinton
    Epidemiology and Biostatistics Program, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA
    Epidemiology 17:162-9. 2006
    ..A large follow-up study of cosmetic breast implant patients previously suggested an overall decrease in mortality but increased risks of brain and respiratory cancers and of suicides...
  52. pmc Estimating water supply arsenic levels in the New England Bladder Cancer Study
    John R Nuckols
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
    Environ Health Perspect 119:1279-85. 2011
    ..Accurate retrospective exposure assessment over a long time period is a major challenge in conducting epidemiologic studies of environmental factors and diseases with long latency, such as cancer...
  53. ncbi request reprint The potential for bias in Cohen's ecological analysis of lung cancer and residential radon
    Jay H Lubin
    Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20892 7244, USA
    J Radiol Prot 22:141-8. 2002
    ..In addition, it is demonstrated that the deleterious association for radon and lung cancer observed in residential and miner studies is consistent with negative trends from ecological studies, of the type described by Cohen...
  54. pmc Cigarette smoking and pancreatic cancer: a pooled analysis from the pancreatic cancer cohort consortium
    Shannon M Lynch
    National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland, USA
    Am J Epidemiol 170:403-13. 2009
    ..This finding and the decline in risk after smoking cessation suggest that smoking has a late-stage effect on pancreatic carcinogenesis...
  55. ncbi request reprint Evidence for an intensity-dependent interaction of NAT2 acetylation genotype and cigarette smoking in the Spanish Bladder Cancer Study
    Jay H Lubin
    Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Rockville, MD 20852, USA
    Int J Epidemiol 36:236-41. 2007
    ..9 in never-smokers and 1.6 in ever-smokers, a 1.8-fold enhancement in smokers. Evidence indicates that acetylation is an exposure-dependent process, and thus the magnitude of the interaction may also depend on exposure level...
  56. pmc Respiratory cancer and inhaled inorganic arsenic in copper smelters workers: a linear relationship with cumulative exposure that increases with concentration
    Jay H Lubin
    Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Rockville, MD 20852, USA
    Environ Health Perspect 116:1661-5. 2008
    ....
  57. doi request reprint Nonsteroidal anti-inflammatory drugs and other analgesic use and bladder cancer in northern New England
    Dalsu Baris
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH DHHS, North Bethesda, MD 20852, USA
    Int J Cancer 132:162-73. 2013
    ..We observed a previously unrecognized risk associated with use of COX-2 inhibitors, which merits further evaluation...
  58. ncbi request reprint A reanalysis of thyroid neoplasms in the Israeli tinea capitis study accounting for dose uncertainties
    Jay H Lubin
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892, USA
    Radiat Res 161:359-68. 2004
    ....
  59. pmc Epidemiologic evaluation of measurement data in the presence of detection limits
    Jay H Lubin
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA
    Environ Health Perspect 112:1691-6. 2004
    ..We illustrate various approaches using measurements of pesticide residues in carpet dust in control subjects from a case-control study of non-Hodgkin lymphoma...
  60. pmc I-131 dose response for incident thyroid cancers in Ukraine related to the Chornobyl accident
    Alina V Brenner
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892 7238, USA
    Environ Health Perspect 119:933-9. 2011
    ..Current knowledge about Chornobyl-related thyroid cancer risks comes from ecological studies based on grouped doses, case-control studies, and studies of prevalent cancers...
  61. ncbi request reprint The association of a tobacco-specific biomarker and cigarette consumption and its dependence on host characteristics
    Jay H Lubin
    Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Rockville, MD 20852, USA
    Cancer Epidemiol Biomarkers Prev 16:1852-7. 2007
    ..Variations in the ratio with host characteristics were generally similar to a recent epidemiologic analysis of effect modification of the association between lung cancer and cigarette smoking...
  62. pmc The Diesel Exhaust in Miners Study: III. Interrelations between respirable elemental carbon and gaseous and particulate components of diesel exhaust derived from area sampling in underground non-metal mining facilities
    Roel Vermeulen
    Division of Cancer Epidemiology and Genetics, US National Cancer Institute, Bethesda, MD 20892, USA
    Ann Occup Hyg 54:762-73. 2010
    ..The fact that CO correlated with REC, loaded on the same factor, and increased linearly in log-log space supported the use of CO in estimating historical exposure levels to DE...
  63. doi request reprint Cigarette smoking and cancer: intensity patterns in the alpha-tocopherol, beta-carotene cancer prevention study in Finnish men
    Jay H Lubin
    Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852
    Am J Epidemiol 167:970-5. 2008
    ..Consistency of intensity patterns suggested a general phenomenon and may provide clues to the molecular basis of smoking-related cancer risk...
  64. pmc Environment And Genetics in Lung cancer Etiology (EAGLE) study: an integrative population-based case-control study of lung cancer
    Maria Teresa Landi
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD, USA
    BMC Public Health 8:203. 2008
    ..A new framework of research is needed to address the challenges offered by this complex disease...
  65. ncbi request reprint Uterine cancer after use of clomiphene citrate to induce ovulation
    Michelle D Althuis
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7234, USA
    Am J Epidemiol 161:607-15. 2005
    ..52, 95% CI: 1.5, 108.0). Clomiphene may increase uterine cancer risk, with higher doses leading to higher risk. Long-term follow-up of infertility cohorts is necessary to clarify the association between clomiphene use and uterine cancer...
  66. pmc Arsenic, internal cancers, and issues in inference from studies of low-level exposures in human populations
    Kenneth P Cantor
    Division of Cancer Epidemiology and Genetics, 8106 EPS, National Cancer Institute, Bethesda, MD 20892 7240, USA
    Toxicol Appl Pharmacol 222:252-7. 2007
    ..Efforts are underway to improve exposure assessment in a large case-control study of bladder cancer in a region of the United States with moderately elevated levels of arsenic in drinking water...
  67. pmc Total exposure and exposure rate effects for alcohol and smoking and risk of head and neck cancer: a pooled analysis of case-control studies
    Jay H Lubin
    Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, MD 20852, USA
    Am J Epidemiol 170:937-47. 2009
    ....
  68. ncbi request reprint Breast cancer mortality among female radiologic technologists in the United States
    Aparna K Mohan
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7244, USA
    J Natl Cancer Inst 94:943-8. 2002
    ..The high risks of breast cancer mortality for women exposed to occupational radiation prior to 1950 and the subsequent decline in risk are consistent with the dramatic reduction in recommended radiation exposure limits over time...
  69. ncbi request reprint Cooking oil fumes and risk of lung cancer in women in rural Gansu, China
    Catherine Metayer
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Rockville EPS 7044, Bethesda, MD 20892, USA
    Lung Cancer 35:111-7. 2002
    ..09). Women exposed to cooking fumes from rapeseed oil appeared to be at increased risk of lung cancer, and there was some evidence that fumes from linseed oil may have also contributed to the risk...
  70. ncbi request reprint The exposure-time-response relationship between occupational asbestos exposure and lung cancer in two German case-control studies
    Michael Hauptmann
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7244, USA
    Am J Ind Med 41:89-97. 2002
    ..Numerous studies have been carried out to evaluate the association between lung cancer and occupational asbestos exposure. However, the effects of timing of exposure have not been analyzed thoroughly...
  71. ncbi request reprint Instrumental measurements of skin color and skin ultraviolet light sensitivity and risk of cutaneous malignant melanoma: a case-control study in an Italian population
    Alina V Brenner
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7362, USA
    Am J Epidemiol 156:353-62. 2002
    ..Epidemiologic studies of CMM may benefit from the inclusion of colorimetric and MED measurements along with traditional risk factors to obtain more accurate, quantitative, and objective information...
  72. ncbi request reprint A quantitative approach for estimating exposure to pesticides in the Agricultural Health Study
    Mustafa Dosemeci
    National Cancer Institute, NIH, Bethesda, MD, USA
    Ann Occup Hyg 46:245-60. 2002
    ....
  73. ncbi request reprint Menopausal hormone replacement therapy and risk of ovarian cancer
    James V Lacey
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Blvd, MSC 7234, Rockville, MD 20852, USA
    JAMA 288:334-41. 2002
    ..The association between menopausal hormone replacement therapy and ovarian cancer is unclear...
  74. ncbi request reprint Prevalence of hepatitis C virus infection and risk for hepatocellular carcinoma and non-Hodgkin lymphoma in AIDS
    Eric A Engels
    Viral Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute NIH, 6120 Executive Boulevard, EPS 8010, Rockville, MD 20892, USA
    J Acquir Immune Defic Syndr 31:536-41. 2002
    ..These data suggest an effect of HCV infection on HCC risk among adults with AIDS. On the other hand, NHL risk was not higher for groups in whom HCV infection was prevalent...
  75. ncbi request reprint Risk of connective tissue disorders among breast implant patients
    Louise A Brinton
    Epidemiology and Biostatistics Program, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA
    Am J Epidemiol 160:619-27. 2004
    ..Given the diagnostic complexities of these diseases, excess risks, if they exist, may be beyond detection even in a study of this size...
  76. ncbi request reprint Inorganic arsenic in drinking water: an evolving public health concern
    Jay H Lubin
    J Natl Cancer Inst 99:906-7. 2007
  77. ncbi request reprint Residential radon and lung cancer risk in a high-exposure area of Gansu Province, China
    Zuoyuan Wang
    Laboratory of Industrial Hygiene, Ministry of Public Health, Beijing, China
    Am J Epidemiol 155:554-64. 2002
    ..Adjusting for exposure uncertainties increased estimates by 50%. Results support increased lung cancer risks with indoor radon exposures that may equal or exceed extrapolations based on miner data...
  78. ncbi request reprint An overview of the North American residential radon and lung cancer case-control studies
    R William Field
    Department of Occupational and Environmental Health, Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, Iowa 52242, USA
    J Toxicol Environ Health A 69:599-631. 2006
    ..Eleven WLM(5-19) is approximately equivalent to an average residential radon exposure of 4 pCi/L for 15 yr, assuming a 70% home occupancy...
  79. ncbi request reprint Modeling the probability of arsenic in groundwater in New England as a tool for exposure assessment
    Joseph D Ayotte
    U S Geological Survey NH VT Water Science Center, 361 Commerce Way, Pembroke, New Hampshire 03275, USA
    Environ Sci Technol 40:3578-85. 2006
    ..Due to the complexity of the fractured bedrock aquifers in the region, well depth and related variables also are not significant predictors...
  80. pmc Bladder cancer mortality and private well use in New England: an ecological study
    Joseph D Ayotte
    US Geological Survey, New Hampshire Vermont Water Science Center, Pembroke, USA
    J Epidemiol Community Health 60:168-72. 2006
    ..To investigate the possible relation between bladder cancer mortality among white men and women and private water use in New England, USA, where rates have been persistently raised and use of private water supplies (wells) common...
  81. ncbi request reprint Persistent organochlorine chemicals in plasma and risk of non-Hodgkin's lymphoma
    Anneclaire J De Roos
    Fred Hutchinson Cancer Research Center and University of Washington Department of Epidemiology, Seattle, Washington 98109 1024, USA
    Cancer Res 65:11214-26. 2005
    ..02-1.79). Our results add to existing literature, which suggests that exposure to organochlorines contributes to non-Hodgkin's lymphoma risk; these risks were most apparent for certain PCBs and furans...
  82. ncbi request reprint Residential radon and risk of lung cancer: a combined analysis of 7 North American case-control studies
    Daniel Krewski
    McLaughlin Centre for Population Health Risk Assessment, University of Ottawa, Ottawa, Ontario, Canada
    Epidemiology 16:137-45. 2005
    ..Residential exposure to radon is at much lower levels, and the risk of lung cancer with residential exposure is less clear. We conducted a systematic analysis of pooled data from all North American residential radon studies...
  83. pmc Cancer risks attributable to low doses of ionizing radiation: assessing what we really know
    David J Brenner
    Center for Radiological Research, Columbia University, 630 West 168th Street, New York, NY 10032, USA
    Proc Natl Acad Sci U S A 100:13761-6. 2003
    ..This linearity assumption is not necessarily the most conservative approach, and it is likely that it will result in an underestimate of some radiation-induced cancer risks and an overestimate of others...
  84. ncbi request reprint Proliferative activity of human thyroid cells in various age groups and its correlation with the risk of thyroid cancer after radiation exposure
    Ali G Saad
    Department of Pathology, University of Cincinnati, 231 Albert Sabin Way, P O Box 670529, Cincinnati, Ohio 45267 0529, USA
    J Clin Endocrinol Metab 91:2672-7. 2006
    ..One of the factors responsible for this phenomenon may be more rapid cell proliferation in children...
  85. ncbi request reprint A combined analysis of North American case-control studies of residential radon and lung cancer
    Daniel Krewski
    Department of Epidemiology and Community Medicine, Faculty of Medicine, McLaughlin Centre for Population Health Risk Assessment, Institute of Population Health, University of Ottawa, Ottawa, Ontario, Canada
    J Toxicol Environ Health A 69:533-97. 2006
    ..Collectively, these results provide direct evidence of an association between residential radon and lung cancer risk, a finding predicted by extrapolation of results from occupational studies of radon-exposed underground miners...