Research Topics
Genomes and GenesSpecies | Jay H LubinSummaryAffiliation: National Institutes of Health Country: USA Publications
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Publications
Risk of lung cancer and residential radon in China: pooled results of two studiesJay H Lubin
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20892, USA
Int J Cancer 109:132-7. 2004....- Cancer incidence among pesticide applicators exposed to metolachlor in the Agricultural Health StudyJennifer A Rusiecki
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20892, USA
Int J Cancer 118:3118-23. 2006.... - Cancer incidence among male pesticide applicators in the Agricultural Health Study cohort exposed to diazinonLaura E Beane Freeman
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20892, USA
Am J Epidemiol 162:1070-9. 2005..Because these results were based on small numbers, additional analyses are necessary as more cases accrue to clarify whether diazinon is associated with cancer risk in humans... 
Atrazine and cancer incidence among pesticide applicators in the agricultural health study (1994-2007)Laura E Beane Freeman
Division of Cancer, Epidemiology, and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
Environ Health Perspect 119:1253-9. 2011..Atrazine is a triazine herbicide used widely in the United States. Although it is an animal carcinogen, the mechanism in rodents does not appear to operate in humans. Few epidemiologic studies have provided evidence for an association...- Methyl bromide exposure and cancer risk in the Agricultural Health StudyKathryn Hughes Barry
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Blvd, Bethesda, MD 20892 7240, USA
Cancer Causes Control 23:807-18. 2012..Although many countries have reduced methyl bromide use because of its ozone depleting properties, some uses remain in the United States and other countries, warranting further investigation of human health effects... - Genetic variation in nucleotide excision repair pathway genes, pesticide exposure and prostate cancer riskKathryn Hughes Barry
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD 20892 7240, USA
Carcinogenesis 33:331-7. 2012..09). In contrast, we did not observe associations among men with other genotypes at these loci. While requiring replication, our findings suggest a role for NER genetic variation in pesticide-associated prostate cancer risk... - Genetic variation in base excision repair pathway genes, pesticide exposure, and prostate cancer riskKathryn Hughes Barry
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland 20892 7240, USA
Environ Health Perspect 119:1726-32. 2011..Previous research indicates increased prostate cancer risk for pesticide applicators and pesticide manufacturing workers. Although underlying mechanisms are unknown, evidence suggests a role of oxidative DNA damage... - Cancer incidence among pesticide applicators exposed to chlorpyrifos in the Agricultural Health StudyWon Jin Lee
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Rockville, MD 20852, USA
J Natl Cancer Inst 96:1781-9. 2004..18 (95% confidence interval = 1.31 to 3.64) times that of those with no chlorpyrifos exposure. CONCLUSION: Our findings suggest an association between chlorpyrifos use and incidence of lung cancer that deserves further evaluation... - The Diesel Exhaust in Miners study: a nested case-control study of lung cancer and diesel exhaustDebra T Silverman
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20816, USA
J Natl Cancer Inst 104:855-68. 2012..Our purpose was to evaluate the relationship between quantitative estimates of exposure to diesel exhaust and lung cancer mortality after adjustment for smoking and other potential confounders... - An examination of male and female odds ratios by BMI, cigarette smoking, and alcohol consumption for cancers of the oral cavity, pharynx, and larynx in pooled data from 15 case-control studiesJay H Lubin
Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Rockville, MD 20852, USA
Cancer Causes Control 22:1217-31. 2011.... - Pendimethalin exposure and cancer incidence among pesticide applicatorsLifang Hou
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852, USA
Epidemiology 17:302-7. 2006..The trends for lung cancer risk were inconsistent for different exposure metrics. CONCLUSIONS: We did not find a clear association of lifetime pendimethalin exposure either with overall cancer incidence or with specific cancer sites... - The Diesel Exhaust in Miners Study: IV. Estimating historical exposures to diesel exhaust in underground non-metal mining facilitiesRoel Vermeulen
Division of Cancer Epidemiology and Genetics, US National Cancer Institute, Bethesda, MD 20892, USA
Ann Occup Hyg 54:774-88. 2010..These REC exposure estimates were in a plausible range and were used in the investigation of exposure-response relationships in epidemiologic analyses... - Chronic obstructive pulmonary disease and altered risk of lung cancer in a population-based case-control studyJill Koshiol
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America
PLoS ONE 4:e7380. 2009..Chronic obstructive pulmonary disease (COPD) has been consistently associated with increased risk of lung cancer. However, previous studies have had limited ability to determine whether the association is due to smoking... - [Influence of menstrual and reproductive factors on the risk of lung cancer]Alina V Brenner
Radiation Epidemiology Branch, Divison of Cancer Epidemiology and Genetics, National Cancer Institute, USA
Zhonghua Liu Xing Bing Xue Za Zhi 25:590-3. 2004..015) and later ages at menopause (trend, P = 0.074). CONCLUSION: Despite limitations, these findings suggested a possible role related to hormones in the etiology of lung cancer in females... - Cigarette smoking and lung cancer: modeling effect modification of total exposure and intensityJay H Lubin
Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20852, USA
Epidemiology 18:639-48. 2007..Above 20 cigarettes per day, there is an "inverse-exposure-rate" effect, ie, the excess odds ratio per pack-year for higher intensity smokers is smaller than for lower-intensity smokers... - Impact of pesticide exposure misclassification on estimates of relative risks in the Agricultural Health StudyAaron Blair
National Cancer Institute, Executive Plaza South, Room 8008, Bethesda, MD 20892, USA
Occup Environ Med 68:537-41. 2011..We evaluate the impact of occupational pesticide exposure misclassification on relative risks using data from the cohort and the AHS Pesticide Exposure Study (AHS/PES)... - Cigarette smoking and cancer risk: modeling total exposure and intensityJay H Lubin
Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
Am J Epidemiol 166:479-89. 2007..The intensity effects were statistically homogeneous, indicating that after accounting for risk from total pack-years, intensity patterns were comparable across the diverse cancer sites... - An update of cancer incidence in the Agricultural Health StudyStella Koutros
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health DHHS, 6120 Executive Blvd, Rockville, MD 20852, USA
J Occup Environ Med 52:1098-105. 2010..Our objective is to reevaluate cancer incidence among Agricultural Health Study participants... - Cancer incidence among pesticide applicators exposed to atrazine in the Agricultural Health StudyJennifer A Rusiecki
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20892-7240, USA
J Natl Cancer Inst 96:1375-82. 2004..However, further studies are warranted for tumor types in which there was a suggestion of trend (lung, bladder, non-Hodgkin lymphoma, and multiple myeloma)... - Cancer and other causes of mortality among radiologic technologists in the United StatesAparna K Mohan
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7244, USA
Int J Cancer 103:259-67. 2003.... - Mortality from lymphohematopoietic malignancies among workers in formaldehyde industries: the National Cancer Institute CohortLaura E Beane Freeman
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD 20892, USA
J Natl Cancer Inst 101:751-61. 2009.... - An updated algorithm for estimation of pesticide exposure intensity in the agricultural health studyJoseph Coble
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20892, USA
Int J Environ Res Public Health 8:4608-22. 2011.... - Lung cancer and indoor exposure to coal and biomass in rural ChinaRuth A Kleinerman
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, EPS 7044, MSC 7238, Bethesda, MD 20892, USA
J Occup Environ Med 44:338-44. 2002..The risk for lung cancer increased relative to the percentage of time that coal was used over the past 30 years (P = 0.02). Our findings suggest that coal may contribute to the risk of lung cancer in this rural area of China... - Pesticide use modifies the association between genetic variants on chromosome 8q24 and prostate cancerStella Koutros
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, Maryland 20852, USA
Cancer Res 70:9224-33. 2010..This is the first report of effect modification between 8q24 and an environmental exposure on prostate cancer risk... - Pesticide use and breast cancer risk among farmers' wives in the agricultural health studyLawrence S Engel
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
Am J Epidemiol 161:121-35. 2005..Further follow-up of this cohort should help clarify the relation between pesticide exposure and breast cancer risk... - Using multiple imputation to assign pesticide use for non-responders in the follow-up questionnaire in the Agricultural Health StudySonya L Heltshe
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA
J Expo Sci Environ Epidemiol 22:409-16. 2012..When appropriately implemented, multiple imputation can reduce bias and increase precision and can be more valid than other missing data approaches... - Factor analysis of pesticide use patterns among pesticide applicators in the Agricultural Health StudyClaudine Samanic
National Cancer Institute, Division of Cancer Epidemiology and Genetics, Bethesda, Maryland, USA
J Expo Anal Environ Epidemiol 15:225-33. 2005..This heterogeneity in exposure patterns may be used to guide etiologic studies of health effects of farmers and other groups exposed to pesticides... - Endometrial carcinoma risks among menopausal estrogen plus progestin and unopposed estrogen users in a cohort of postmenopausal womenJames V Lacey
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland, USA
Cancer Epidemiol Biomarkers Prev 14:1724-31. 2005..However, endometrial carcinoma risks among estrogen plus progestin users and among former unopposed estrogen users are not firmly established... - Dietary quercetin, quercetin-gene interaction, metabolic gene expression in lung tissue and lung cancer riskTram Kim Lam
Cancer Prevention Fellowship Program, Office of Preventive Oncology, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
Carcinogenesis 31:634-42. 2010..Our findings suggest an interplay between quercetin intake, tobacco smoking, and lung cancer risk. Further research on this relationship is warranted... - Cancer incidence among pesticide applicators exposed to alachlor in the Agricultural Health StudyWon Jin Lee
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852, USA
Am J Epidemiol 159:373-80. 2004..Our findings suggest a possible association between alachlor application and incidence of lymphohematopoietic cancers among applicators in the Agricultural Health Study... - Mortality from solid cancers among workers in formaldehyde industriesMichael Hauptmann
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Bethesda, MD 20892, USA
Am J Epidemiol 159:1117-30. 2004..In this cohort of formaldehyde-industry workers, some evidence was found of an exposure-response relation with mortality from nasopharyngeal cancer (based on small numbers) but not for cancers of the pancreas, brain, lung, or prostate... - Xenobiotic-metabolizing gene variants, pesticide use, and the risk of prostate cancerStella Koutros
Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20852, USA
Pharmacogenet Genomics 21:615-23. 2011..OBECTIVE: We evaluated pesticide-SNP interactions between 45 pesticides and 1913 XME SNPs with respect to prostrate cancer among 776 cases and 1444 controls in the Agricultural Health Study... - Body mass index, cigarette smoking, and alcohol consumption and cancers of the oral cavity, pharynx, and larynx: modeling odds ratios in pooled case-control dataJay H Lubin
Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Rockville, MD 20852, USA
Am J Epidemiol 171:1250-61. 2010.... - Mood disorders and risk of lung cancer in the EAGLE case-control study and in the U.S. Veterans Affairs inpatient cohortDavid E Capo-Ramos
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
PLoS ONE 7:e42945. 2012..Mood disorders may affect lung cancer risk. We evaluated this hypothesis in two large studies... - Weight, height, and body mass index and risk for ovarian cancer in a cohort studyJames V Lacey
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville 20852 7234, MD
Ann Epidemiol 16:869-76. 2006..Reported associations between ovarian cancer and body size are inconsistent. We assessed ovarian cancer and anthropometry in the Breast Cancer Detection Demonstration Project Follow-Up Study... - Methodological issues regarding confounding and exposure misclassification in epidemiological studies of occupational exposuresAaron Blair
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, Maryland 20892, USA
Am J Ind Med 50:199-207. 2007..Although it is important to consider the potential for limitations of epidemiologic investigations, judgment regarding their importance should be based on their actual likelihood of occurrence... - Phase I metabolic genes and risk of lung cancer: multiple polymorphisms and mRNA expressionMelissa Rotunno
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
PLoS ONE 4:e5652. 2009..Our findings emphasize the necessity of post-GWAS fine mapping and SNP functional assessment to further elucidate cancer risk associations... - Menstrual and reproductive factors and risk of lung cancer among Chinese women, Eastern Gansu Province, 1994-1998Alina V Brenner
Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Rockville, EPS, Bethesda, MD 20892, USA
J Epidemiol 13:22-8. 2003..Odds ratios were lower for later ages at menarche (trend, P = 0.015) and later ages at menopause (trend, P = 0.074). Despite limitations, these findings suggest a possible role of hormones in the etiology of lung cancer in females... - Cancer incidence in the agricultural health studyMichael C R Alavanja
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20892, USA
Scand J Work Environ Health 31:39-45; discussion 5-7. 2005..This large, prospective cohort study of private applicators, commercial applicators, and spouses of farmer applicators was undertaken to ascertain the etiology of cancers elevated in agriculture... - The importance of exposure rate on odds ratios by cigarette smoking and alcohol consumption for esophageal adenocarcinoma and squamous cell carcinoma in the Barrett's Esophagus and Esophageal Adenocarcinoma ConsortiumJay H Lubin
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH DHHS, Bethesda, MD 20892, USA
Cancer Epidemiol 36:306-16. 2012..e., the impact on the OR for a fixed total exposure of high exposure rate for short duration compared with low exposure rate for long duration... - Mortality from lymphohematopoietic malignancies among workers in formaldehyde industriesMichael Hauptmann
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
J Natl Cancer Inst 95:1615-23. 2003..We extended follow-up of a cohort of industrial workers to evaluate the association between formaldehyde exposure and lymphohematopoietic cancers... - Lower risk of lung cancer after multiple pneumonia diagnosesJill Koshiol
Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, MSC 7248, Bethesda, MD 20892 7248, USA
Cancer Epidemiol Biomarkers Prev 19:716-21. 2010..Although pneumonia has been suggested as a risk factor for lung cancer, previous studies have not evaluated the influence of number of pneumonia diagnoses in relation to lung cancer risk... - Cigarette smoking and lung cancer: modeling total exposure and intensityJay H Lubin
Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Rockville, MD 20852, USA
Cancer Epidemiol Biomarkers Prev 15:517-23. 2006..e., smoking at a lower intensity for longer duration is more deleterious than smoking at a higher intensity for shorter duration)... - Radon, secondhand smoke, glutathione-S-transferase M1 and lung cancer among womenMatthew R Bonner
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Rockville, MD, USA
Int J Cancer 119:1462-7. 2006..Additionally, these findings support the hypothesis that radon and SHS promote neoplasia through shared elements of a common pathway... - Cigarette smoking and pancreatic cancer: a pooled analysis from the pancreatic cancer cohort consortiumShannon M Lynch
National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland, USA
Am J Epidemiol 170:403-13. 2009..This finding and the decline in risk after smoking cessation suggest that smoking has a late-stage effect on pancreatic carcinogenesis... - The potential for bias in Cohen's ecological analysis of lung cancer and residential radonJay H Lubin
Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20892 7244, USA
J Radiol Prot 22:141-8. 2002..In addition, it is demonstrated that the deleterious association for radon and lung cancer observed in residential and miner studies is consistent with negative trends from ecological studies, of the type described by Cohen... - Respiratory cancer and inhaled inorganic arsenic in copper smelters workers: a linear relationship with cumulative exposure that increases with concentrationJay H Lubin
Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Rockville, MD 20852, USA
Environ Health Perspect 116:1661-5. 2008.... - Mortality rates among augmentation mammoplasty patients: an updateLouise A Brinton
Epidemiology and Biostatistics Program, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA
Epidemiology 17:162-9. 2006..A large follow-up study of cosmetic breast implant patients previously suggested an overall decrease in mortality but increased risks of brain and respiratory cancers and of suicides... - Estimating water supply arsenic levels in the New England Bladder Cancer StudyJohn R Nuckols
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
Environ Health Perspect 119:1279-85. 2011..Accurate retrospective exposure assessment over a long time period is a major challenge in conducting epidemiologic studies of environmental factors and diseases with long latency, such as cancer... - Evidence for an intensity-dependent interaction of NAT2 acetylation genotype and cigarette smoking in the Spanish Bladder Cancer StudyJay H Lubin
Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Rockville, MD 20852, USA
Int J Epidemiol 36:236-41. 2007..9 in never-smokers and 1.6 in ever-smokers, a 1.8-fold enhancement in smokers. Evidence indicates that acetylation is an exposure-dependent process, and thus the magnitude of the interaction may also depend on exposure level... - A reanalysis of thyroid neoplasms in the Israeli tinea capitis study accounting for dose uncertaintiesJay H Lubin
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892, USA
Radiat Res 161:359-68. 2004.... - Epidemiologic evaluation of measurement data in the presence of detection limitsJay H Lubin
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA
Environ Health Perspect 112:1691-6. 2004..We illustrate various approaches using measurements of pesticide residues in carpet dust in control subjects from a case-control study of non-Hodgkin lymphoma... - The Diesel Exhaust in Miners Study: III. Interrelations between respirable elemental carbon and gaseous and particulate components of diesel exhaust derived from area sampling in underground non-metal mining facilitiesRoel Vermeulen
Division of Cancer Epidemiology and Genetics, US National Cancer Institute, Bethesda, MD 20892, USA
Ann Occup Hyg 54:762-73. 2010..The fact that CO correlated with REC, loaded on the same factor, and increased linearly in log-log space supported the use of CO in estimating historical exposure levels to DE... - I-131 dose response for incident thyroid cancers in Ukraine related to the Chornobyl accidentAlina V Brenner
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892 7238, USA
Environ Health Perspect 119:933-9. 2011..Current knowledge about Chornobyl-related thyroid cancer risks comes from ecological studies based on grouped doses, case-control studies, and studies of prevalent cancers... 
Cigarette smoking and cancer: intensity patterns in the alpha-tocopherol, beta-carotene cancer prevention study in Finnish menJay H Lubin
Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852
Am J Epidemiol 167:970-5. 2008..Consistency of intensity patterns suggested a general phenomenon and may provide clues to the molecular basis of smoking-related cancer risk...- The association of a tobacco-specific biomarker and cigarette consumption and its dependence on host characteristicsJay H Lubin
Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Rockville, MD 20852, USA
Cancer Epidemiol Biomarkers Prev 16:1852-7. 2007..Variations in the ratio with host characteristics were generally similar to a recent epidemiologic analysis of effect modification of the association between lung cancer and cigarette smoking... - GSTM1 and GSTT1 copy numbers and mRNA expression in lung cancerMelissa Rotunno
Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892 7248, USA
Mol Carcinog 51:E142-50. 2012..A protective effect of the same mutations may be operative in never-smokers and women, possibly because of reduced activity of other genotoxic chemicals... - Nonsteroidal anti-inflammatory drugs and other analgesic use and bladder cancer in northern New EnglandDalsu Baris
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH DHHS, North Bethesda, MD 20852, USA
Int J Cancer 132:162-73. 2013..We observed a previously unrecognized risk associated with use of COX-2 inhibitors, which merits further evaluation... - Arsenic, internal cancers, and issues in inference from studies of low-level exposures in human populationsKenneth P Cantor
Division of Cancer Epidemiology and Genetics, 8106 EPS, National Cancer Institute, Bethesda, MD 20892 7240, USA
Toxicol Appl Pharmacol 222:252-7. 2007..Efforts are underway to improve exposure assessment in a large case-control study of bladder cancer in a region of the United States with moderately elevated levels of arsenic in drinking water... - Menstrual and reproductive factors and gastric cancer risk in a large prospective study of womenNeal D Freedman
Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
Gut 56:1671-7. 2007..Gastric cancer incidence rates are consistently lower in women than men in both high and low-risk regions worldwide. Sex hormones, such as progesterone and estrogen, may protect women against gastric cancer... - Total exposure and exposure rate effects for alcohol and smoking and risk of head and neck cancer: a pooled analysis of case-control studiesJay H Lubin
Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, MD 20852, USA
Am J Epidemiol 170:937-47. 2009.... - Uterine cancer after use of clomiphene citrate to induce ovulationMichelle D Althuis
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7234, USA
Am J Epidemiol 161:607-15. 2005..52, 95% CI: 1.5, 108.0). Clomiphene may increase uterine cancer risk, with higher doses leading to higher risk. Long-term follow-up of infertility cohorts is necessary to clarify the association between clomiphene use and uterine cancer... - Environment And Genetics in Lung cancer Etiology (EAGLE) study: an integrative population-based case-control study of lung cancerMaria Teresa Landi
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD, USA
BMC Public Health 8:203. 2008..A new framework of research is needed to address the challenges offered by this complex disease... - The exposure-time-response relationship between occupational asbestos exposure and lung cancer in two German case-control studiesMichael Hauptmann
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7244, USA
Am J Ind Med 41:89-97. 2002..Numerous studies have been carried out to evaluate the association between lung cancer and occupational asbestos exposure. However, the effects of timing of exposure have not been analyzed thoroughly... - Breast cancer mortality among female radiologic technologists in the United StatesAparna K Mohan
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7244, USA
J Natl Cancer Inst 94:943-8. 2002..The high risks of breast cancer mortality for women exposed to occupational radiation prior to 1950 and the subsequent decline in risk are consistent with the dramatic reduction in recommended radiation exposure limits over time... - Cooking oil fumes and risk of lung cancer in women in rural Gansu, ChinaCatherine Metayer
Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Rockville EPS/7044, Bethesda, MD 20892, USA
Lung Cancer 35:111-7. 2002..09). Women exposed to cooking fumes from rapeseed oil appeared to be at increased risk of lung cancer, and there was some evidence that fumes from linseed oil may have also contributed to the risk... - Instrumental measurements of skin color and skin ultraviolet light sensitivity and risk of cutaneous malignant melanoma: a case-control study in an Italian populationAlina V Brenner
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892-7362, USA
Am J Epidemiol 156:353-62. 2002..Epidemiologic studies of CMM may benefit from the inclusion of colorimetric and MED measurements along with traditional risk factors to obtain more accurate, quantitative, and objective information... - A quantitative approach for estimating exposure to pesticides in the Agricultural Health StudyMustafa Dosemeci
National Cancer Institute, NIH, Bethesda, MD, USA
Ann Occup Hyg 46:245-60. 2002.... - Menopausal hormone replacement therapy and risk of ovarian cancerJames V Lacey
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Blvd, MSC 7234, Rockville, MD 20852, USA
JAMA 288:334-41. 2002..The association between menopausal hormone replacement therapy and ovarian cancer is unclear... - Prevalence of hepatitis C virus infection and risk for hepatocellular carcinoma and non-Hodgkin lymphoma in AIDSEric A Engels
Viral Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute NIH, 6120 Executive Boulevard, EPS 8010, Rockville, MD 20892, USA
J Acquir Immune Defic Syndr 31:536-41. 2002..These data suggest an effect of HCV infection on HCC risk among adults with AIDS. On the other hand, NHL risk was not higher for groups in whom HCV infection was prevalent... - Risk of connective tissue disorders among breast implant patientsLouise A Brinton
Epidemiology and Biostatistics Program, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA
Am J Epidemiol 160:619-27. 2004..Given the diagnostic complexities of these diseases, excess risks, if they exist, may be beyond detection even in a study of this size... - Residential radon and risk of lung cancer: a combined analysis of 7 North American case-control studiesDaniel Krewski
McLaughlin Centre for Population Health Risk Assessment, University of Ottawa, Ottawa, Ontario, Canada
Epidemiology 16:137-45. 2005..Residential exposure to radon is at much lower levels, and the risk of lung cancer with residential exposure is less clear. We conducted a systematic analysis of pooled data from all North American residential radon studies... - Residential radon and lung cancer risk in a high-exposure area of Gansu Province, ChinaZuoyuan Wang
Laboratory of Industrial Hygiene, Ministry of Public Health, Beijing, China
Am J Epidemiol 155:554-64. 2002..Adjusting for exposure uncertainties increased estimates by 50%. Results support increased lung cancer risks with indoor radon exposures that may equal or exceed extrapolations based on miner data... - Inorganic arsenic in drinking water: an evolving public health concernJay H Lubin
J Natl Cancer Inst 99:906-7. 2007 - Proliferative activity of human thyroid cells in various age groups and its correlation with the risk of thyroid cancer after radiation exposureAli G Saad
Department of Pathology, University of Cincinnati, 231 Albert Sabin Way, P.O. Box 670529, Cincinnati, Ohio 45267-0529, USA
J Clin Endocrinol Metab 91:2672-7. 2006..However, the variation in the rate of cell proliferation is unlikely to be responsible entirely for this phenomenon and other factors may also be involved... - An overview of the North American residential radon and lung cancer case-control studiesR William Field
Department of Occupational and Environmental Health, Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, Iowa 52242, USA
J Toxicol Environ Health A 69:599-631. 2006..Eleven WLM(5-19) is approximately equivalent to an average residential radon exposure of 4 pCi/L for 15 yr, assuming a 70% home occupancy... - A combined analysis of North American case-control studies of residential radon and lung cancerDaniel Krewski
Department of Epidemiology and Community Medicine, Faculty of Medicine, McLaughlin Centre for Population Health Risk Assessment, Institute of Population Health, University of Ottawa, Ottawa, Ontario, Canada
J Toxicol Environ Health A 69:533-97. 2006..Collectively, these results provide direct evidence of an association between residential radon and lung cancer risk, a finding predicted by extrapolation of results from occupational studies of radon-exposed underground miners... - Cancer risks attributable to low doses of ionizing radiation: assessing what we really knowDavid J Brenner
Center for Radiological Research, Columbia University, 630 West 168th Street, New York, NY 10032, USA
Proc Natl Acad Sci U S A 100:13761-6. 2003..This linearity assumption is not necessarily the most conservative approach, and it is likely that it will result in an underestimate of some radiation-induced cancer risks and an overestimate of others... - Bladder cancer mortality and private well use in New England: an ecological studyJoseph D Ayotte
US Geological Survey, New Hampshire-Vermont Water Science Center, Pembroke, USA
J Epidemiol Community Health 60:168-72. 2006..Analytical studies are underway to clarify the relation between suspected water contaminants, particularly arsenic, and raised bladder cancer rates in northern New England... - Modeling the probability of arsenic in groundwater in New England as a tool for exposure assessmentJoseph D Ayotte
U S Geological Survey NH VT Water Science Center, 361 Commerce Way, Pembroke, New Hampshire 03275, USA
Environ Sci Technol 40:3578-85. 2006..Due to the complexity of the fractured bedrock aquifers in the region, well depth and related variables also are not significant predictors... - Persistent organochlorine chemicals in plasma and risk of non-Hodgkin's lymphomaAnneclaire J De Roos
Fred Hutchinson Cancer Research Center and University of Washington Department of Epidemiology, Seattle, Washington 98109 1024, USA
Cancer Res 65:11214-26. 2005..02-1.79). Our results add to existing literature, which suggests that exposure to organochlorines contributes to non-Hodgkin's lymphoma risk; these risks were most apparent for certain PCBs and furans...