Yuan Lu

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc A kinase anchor protein 150 (AKAP150)-associated protein kinase A limits dendritic spine density
    Yuan Lu
    Department of Pharmacology, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, Iowa 52242, USA
    J Biol Chem 286:26496-506. 2011
  2. pmc AKAP150-anchored PKA activity is important for LTD during its induction phase
    Yuan Lu
    Department of Pharmacology, Roy J and Lucille A Carver College of Medicine, University of Iowa, 51 Newton Road, Iowa City, IA 52242 1109, USA
    J Physiol 586:4155-64. 2008
  3. pmc The bed nucleus of the stria terminalis is critical for anxiety-related behavior evoked by CO2 and acidosis
    Rebecca J Taugher
    Interdisciplinary Graduate Program in Neuroscience, University of Iowa, Iowa City, Iowa 52242, Department of Psychiatry, University of Iowa, Iowa City, Iowa 52242
    J Neurosci 34:10247-55. 2014
  4. pmc Age-dependent requirement of AKAP150-anchored PKA and GluR2-lacking AMPA receptors in LTP
    Yuan Lu
    Department of Pharmacology, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA 52242 1109, USA
    EMBO J 26:4879-90. 2007
  5. pmc Acid-sensing ion channels contribute to synaptic transmission and inhibit cocaine-evoked plasticity
    Collin J Kreple
    1 Medical Scientist Training Program, University of Iowa, Iowa City, Iowa, USA 2 Department of Molecular Physiology and Biophysics, University of Iowa, Iowa City, Iowa, USA 3
    Nat Neurosci 17:1083-91. 2014
  6. pmc Drug abuse and the simplest neurotransmitter
    Collin J Kreple
    Medical Scientist Training Program, Department of Molecular Physiology and Biophysics, Department of Psychiatry, Interdisciplinary Graduate Program in Neuroscience, Department of Psychology, and Department of Neurosurgery, University of Iowa, Iowa City, Iowa 52242, United States
    ACS Chem Neurosci 5:746-8. 2014
  7. pmc Protons are a neurotransmitter that regulates synaptic plasticity in the lateral amygdala
    Jianyang Du
    Howard Hughes Medical Institute andDepartment of Internal Medicine, Roy J and Lucille A Carver College of Medicine, Iowa City, IA 52242
    Proc Natl Acad Sci U S A 111:8961-6. 2014
  8. pmc Forebrain glutamatergic neurons mediate leptin action on depression-like behaviors and synaptic depression
    Ming Guo
    Department of Pharmacology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA
    Transl Psychiatry 2:e83. 2012

Collaborators

Detail Information

Publications8

  1. pmc A kinase anchor protein 150 (AKAP150)-associated protein kinase A limits dendritic spine density
    Yuan Lu
    Department of Pharmacology, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, Iowa 52242, USA
    J Biol Chem 286:26496-506. 2011
    ..However, synaptic transmission and spine density was normal at 8 weeks in KO and D36 mice. Thus AKAP150-independent mechanisms correct the aberrantly high number of active spines in juvenile AKAP150 KO and D36 mice during development...
  2. pmc AKAP150-anchored PKA activity is important for LTD during its induction phase
    Yuan Lu
    Department of Pharmacology, Roy J and Lucille A Carver College of Medicine, University of Iowa, 51 Newton Road, Iowa City, IA 52242 1109, USA
    J Physiol 586:4155-64. 2008
    ..Collectively our data indicate that AKAP150-anchored PKA activity is required to induce LTD and not merely to maintain a tonically heightened activity level of AMPA receptors as proposed earlier...
  3. pmc The bed nucleus of the stria terminalis is critical for anxiety-related behavior evoked by CO2 and acidosis
    Rebecca J Taugher
    Interdisciplinary Graduate Program in Neuroscience, University of Iowa, Iowa City, Iowa 52242, Department of Psychiatry, University of Iowa, Iowa City, Iowa 52242
    J Neurosci 34:10247-55. 2014
    ..Together, these findings identify the BNST as an extra-amygdalar fear circuit structure important in CO2-evoked fear-related behavior. ..
  4. pmc Age-dependent requirement of AKAP150-anchored PKA and GluR2-lacking AMPA receptors in LTP
    Yuan Lu
    Department of Pharmacology, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA 52242 1109, USA
    EMBO J 26:4879-90. 2007
    ..AKAP150-anchored PKA might thus critically contribute to LTP in adult hippocampus in part by phosphorylating GluR1 to foster postsynaptic accumulation of homomeric GluR1 AMPA receptors during initial LTP in 8-week-old mice...
  5. pmc Acid-sensing ion channels contribute to synaptic transmission and inhibit cocaine-evoked plasticity
    Collin J Kreple
    1 Medical Scientist Training Program, University of Iowa, Iowa City, Iowa, USA 2 Department of Molecular Physiology and Biophysics, University of Iowa, Iowa City, Iowa, USA 3
    Nat Neurosci 17:1083-91. 2014
    ..Together, these data suggest that ASIC1A inhibits the plasticity underlying addiction-related behavior and raise the possibility of developing therapies for drug addiction by targeting ASIC-dependent neurotransmission. ..
  6. pmc Drug abuse and the simplest neurotransmitter
    Collin J Kreple
    Medical Scientist Training Program, Department of Molecular Physiology and Biophysics, Department of Psychiatry, Interdisciplinary Graduate Program in Neuroscience, Department of Psychology, and Department of Neurosurgery, University of Iowa, Iowa City, Iowa 52242, United States
    ACS Chem Neurosci 5:746-8. 2014
    ....
  7. pmc Protons are a neurotransmitter that regulates synaptic plasticity in the lateral amygdala
    Jianyang Du
    Howard Hughes Medical Institute andDepartment of Internal Medicine, Roy J and Lucille A Carver College of Medicine, Iowa City, IA 52242
    Proc Natl Acad Sci U S A 111:8961-6. 2014
    ..They also indicate that protons and ASICs are a neurotransmitter/receptor pair critical for amygdala-dependent learning and memory. ..
  8. pmc Forebrain glutamatergic neurons mediate leptin action on depression-like behaviors and synaptic depression
    Ming Guo
    Department of Pharmacology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA
    Transl Psychiatry 2:e83. 2012
    ....