Yuan Lu

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc A kinase anchor protein 150 (AKAP150)-associated protein kinase A limits dendritic spine density
    Yuan Lu
    Department of Pharmacology, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, Iowa 52242, USA
    J Biol Chem 286:26496-506. 2011
  2. pmc AKAP150-anchored PKA activity is important for LTD during its induction phase
    Yuan Lu
    Department of Pharmacology, Roy J and Lucille A Carver College of Medicine, University of Iowa, 51 Newton Road, Iowa City, IA 52242 1109, USA
    J Physiol 586:4155-64. 2008
  3. pmc Age-dependent requirement of AKAP150-anchored PKA and GluR2-lacking AMPA receptors in LTP
    Yuan Lu
    Department of Pharmacology, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA 52242 1109, USA
    EMBO J 26:4879-90. 2007
  4. pmc Forebrain glutamatergic neurons mediate leptin action on depression-like behaviors and synaptic depression
    Ming Guo
    Department of Pharmacology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA
    Transl Psychiatry 2:e83. 2012

Detail Information

Publications4

  1. pmc A kinase anchor protein 150 (AKAP150)-associated protein kinase A limits dendritic spine density
    Yuan Lu
    Department of Pharmacology, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, Iowa 52242, USA
    J Biol Chem 286:26496-506. 2011
    ..However, synaptic transmission and spine density was normal at 8 weeks in KO and D36 mice. Thus AKAP150-independent mechanisms correct the aberrantly high number of active spines in juvenile AKAP150 KO and D36 mice during development...
  2. pmc AKAP150-anchored PKA activity is important for LTD during its induction phase
    Yuan Lu
    Department of Pharmacology, Roy J and Lucille A Carver College of Medicine, University of Iowa, 51 Newton Road, Iowa City, IA 52242 1109, USA
    J Physiol 586:4155-64. 2008
    ..Collectively our data indicate that AKAP150-anchored PKA activity is required to induce LTD and not merely to maintain a tonically heightened activity level of AMPA receptors as proposed earlier...
  3. pmc Age-dependent requirement of AKAP150-anchored PKA and GluR2-lacking AMPA receptors in LTP
    Yuan Lu
    Department of Pharmacology, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA 52242 1109, USA
    EMBO J 26:4879-90. 2007
    ..AKAP150-anchored PKA might thus critically contribute to LTP in adult hippocampus in part by phosphorylating GluR1 to foster postsynaptic accumulation of homomeric GluR1 AMPA receptors during initial LTP in 8-week-old mice...
  4. pmc Forebrain glutamatergic neurons mediate leptin action on depression-like behaviors and synaptic depression
    Ming Guo
    Department of Pharmacology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA
    Transl Psychiatry 2:e83. 2012
    ....