Research Topics
| Job E LopezSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Relapsing fever spirochetes retain infectivity after prolonged in vitro cultivationJob E Lopez
Laboratory of Zoonotic Pathogens, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana 59840, USA
Vector Borne Zoonotic Dis 8:813-20. 2008..Therefore, these results suggest that relapsing fever spirochetes are genetically stable during in vitro cultivation, and the fhbA-containing segment of DNA that is lost during cultivation is not required for infection...
Identification of conserved antigens for early serodiagnosis of relapsing fever BorreliaJob E Lopez
Laboratory of Zoonotic Pathogens, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840, USA
Microbiology 155:2641-51. 2009..hermsii and Borrelia recurrentis. These results identify a much larger set of immunoreactive proteins, and could help in the early serodiagnosis of this tick-borne infection...
A novel surface antigen of relapsing fever spirochetes can discriminate between relapsing fever and Lyme borreliosisJob E Lopez
Laboratory of Zoonotic Pathogens, Rocky Mountain Laboratories, 903 South 4th St, Hamilton, MT 59840, USA
Clin Vaccine Immunol 17:564-71. 2010..Lastly, in silico and experimental analysis indicated that BipA is a surface-exposed lipoprotein in B. hermsii. These findings enhance the capabilities of diagnosing infection with relapsing fever spirochetes...
Acquisition and subsequent transmission of Borrelia hermsii by the soft tick Ornithodoros hermsiJob E Lopez
Laboratory of Zoonotic Pathogens, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana 59840, USA
J Med Entomol 48:891-5. 2011....
Endemic foci of the tick-borne relapsing fever spirochete Borrelia crocidurae in Mali, West Africa, and the potential for human infectionTom G Schwan
Laboratory of Zoonotic Pathogens, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, Montana, United States of America
PLoS Negl Trop Dis 6:e1924. 2012....
Bloodmeal size and spirochete acquisition of Ornithodoros hermsi (Acari: Argasidae) during feedingBrandi N McCoy
Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840, USA
J Med Entomol 47:1164-72. 2010..These observations establish a basis for future studies to determine the minimum number of spirochetes required in the host's blood to allow O. hermsi to become persistently infected and transmit during subsequent bloodmeals...
Detection of Lassa virus, MaliDavid Safronetz
National Institutes of Health, Hamilton, Montana 59840, USA
Emerg Infect Dis 16:1123-6. 2010..We report the isolation and genetic characterization of Lassa virus from an area previously unknown for Lassa fever...
