Research Topics
Genomes and GenesSpecies | H C LookerSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Gestational glucose tolerance and risk of type 2 diabetes in young Pima Indian offspringPaul W Franks
Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Arizona, USA
Diabetes 55:460-5. 2006..Thus, prevention of offspring type 2 diabetes may require strategies that focus on improving gestational glucose tolerance even within the normal range...
Childhood obesity, other cardiovascular risk factors, and premature deathPaul W Franks
Diabetes Epidemiology and Clinical Research Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, AZ, USA
N Engl J Med 362:485-93. 2010..The effect of childhood risk factors for cardiovascular disease on adult mortality is poorly understood...- Longitudinal studies of incidence and progression of diabetic retinopathy assessed by retinal photography in pima indiansHelen C Looker
Diabetes and Arthritis Epidemiology Section, National Institute of Diabetes and Digestive and Kidney Diseases, Phoenix, Arizona, USA
Diabetes Care 26:320-6. 2003..To examine incidence and progression of retinopathy using retinal photographs in Pima Indians and to compare the results with those obtained when retinopathy is assessed by direct ophthalmoscopy... - Changes in BMI and weight before and after the development of type 2 diabetesH C Looker
Diabetes and Arthritis Epidemiology Section, National Institute of Diabetes and Digestive and Kidney Diseases, Phoenix, Arizona 85014, USA
Diabetes Care 24:1917-22. 2001..To examine weight changes occurring before and after the diagnosis of diabetes and the association of these changes with treatment and microvascular complications... - Homocysteine as a risk factor for nephropathy and retinopathy in Type 2 diabetesH C Looker
1550 E Indian School Road, Phoenix, Arizona 85014, USA
Diabetologia 46:766-72. 2003..The aim of this study was to examine the relation between serum total homocysteine concentrations and microvascular complications in Pima Indians with Type 2 diabetes... - Homocysteine and vitamin B(12) concentrations and mortality rates in type 2 diabetesHelen C Looker
National Institute of Diabetes and Digestive and Kidney Diseases, Phoenix, AZ, USA
Diabetes Metab Res Rev 23:193-201. 2007..To assess the role of homocysteine as a risk factor for mortality in diabetic subjects... - Adiponectin concentrations are influenced by renal function and diabetes duration in Pima Indians with type 2 diabetesHelen C Looker
National Institute of Diabetes and Digestive and Kidney Diseases, Phoenix, Arizona 85014, USA
J Clin Endocrinol Metab 89:4010-7. 2004..0001). Serum adiponectin is lowest in the presence of impaired glucose regulation and early diabetes. In the presence of diabetes, serum adiponectin is positively associated with abnormal renal function and diabetes duration... - Increasing incidence of proteinuria and declining incidence of end-stage renal disease in diabetic Pima IndiansM E Pavkov
Diabetes Epidemiology and Clinical Research Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona, USA
Kidney Int 70:1840-6. 2006..On the other hand, the incidence of ESRD declined after 1990, coinciding with improved control of blood pressure, hyperglycemia, and perhaps other risk factors... - Do measures of body fat distribution provide information on the risk of type 2 diabetes in addition to measures of general obesity? Comparison of anthropometric predictors of type 2 diabetes in Pima IndiansMarshall K Tulloch-Reid
Diabetes and Arthritis Epidemiology Section, Phoenix Epidemiology and Clinical Research Branch, NIDDK National Institutes of Health, Phoenix, Arizona, USA
Diabetes Care 26:2556-61. 2003.... - Childhood predictors of young-onset type 2 diabetesPaul W Franks
Diabetes Epidemiology and Clinical Research Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 1550 E Indian School Rd, Phoenix, AZ 85014, USA
Diabetes 56:2964-72. 2007..Optimal prevention of young-onset type 2 diabetes requires identification of the early-life modifiable risk factors. We aimed to do this using longitudinal data in 1,604 5- to 19-year-old initially nondiabetic American Indians... - Incidence of retinopathy and nephropathy in youth-onset compared with adult-onset type 2 diabetesJonathan Krakoff
National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona 85014, USA
Diabetes Care 26:76-81. 2003..To examine the risk of retinopathy and nephropathy in participants in whom type 2 diabetes was diagnosed in youth (before 20 years of age) compared with those in whom type 2 diabetes was diagnosed at older ages... - Plasma glucose regulation and mortality in pima IndiansNan Hee Kim
Diabetes Epidemiology and Clinical Research Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona 85014 4972, USA
Diabetes Care 31:488-92. 2008.... - Effect of periodontitis on overt nephropathy and end-stage renal disease in type 2 diabetesWendy A Shultis
Diabetes Epidemiology and Clinical Research Section, Phoenix Epidemiology and Clinical Research Branch, National Institutes of Health, 1550 E Indian School Rd, Phoenix, AZ 85014 4972, USA
Diabetes Care 30:306-11. 2007..The purpose of this study was to investigate the effect of periodontitis on development of overt nephropathy, defined as macroalbuminuria, and end-stage renal disease (ESRD) in type 2 diabetes... - Exploration of non-hierarchical classification methods combined with linkage analysis to identify loci influencing clusters of co-regulated transcriptsAlka Malhotra
Genetic Basis of Human Disease Division, Translational Genomics Research Institute, 445 North Fifth Street, Phoenix, Arizona 85004, USA
BMC Proc 1:S48. 2007.... - Early growth in offspring of diabetic mothersLeslie Touger
Diabetes Epidemiology and Clinical Research Section, National Institute of Diabetes and Digestive and Kidney Diseases, 1550 E Indian School Rd, Phoenix, AZ 85014, USA
Diabetes Care 28:585-9. 2005..By age 5 years, offspring of diabetic mothers (ODMs) are heavier and have altered glucose metabolism compared with offspring of mothers without diabetes (non-DMs). This study evaluates the growth pattern of ODMs before the age of 5 years... - Interaction between an 11betaHSD1 gene variant and birth era modifies the risk of hypertension in Pima IndiansPaul W Franks
Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 1550 E Indian School Rd, Phoenix, AZ 85014, USA
Hypertension 44:681-8. 2004..These data demonstrate association between genetic variability at 11betaHSD1 with hypertension, but these effects are modified by environmental factors... - Genome-wide linkage analyses to identify Loci for diabetic retinopathyHelen C Looker
PECRB, NIDDK, 1550 E Indian School Rd, Phoenix, AZ 85014, USA
Diabetes 56:1160-6. 2007..2 cM), whereas with multipoint analysis the peak LOD was 2.58 at 35 cM. No other areas of suggestive linkage were found. We propose that an area on chromosome 1 may harbor a gene or genes conferring susceptibility to diabetic retinopathy... - Hematocrit and the incidence of type 2 diabetes in the pima indiansMarshall K Tulloch-Reid
Diabetes and Arthritis Epidemiology Section, Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 1550 East Indian School Rd, Phoenix, AZ 85014, USA
Diabetes Care 27:2245-6. 2004 - Depression, diabetes, and glycemic control in an American Indian communityPuneet K C Sahota
National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona 85014, USA
J Clin Psychiatry 69:800-9. 2008.... - Design and analysis of genetic association studies to finely map a locus identified by linkage analysis: sample size and power calculationsR L Hanson
Diabetes Epidemiology and Clinical Research Section, National Institute of Diabetes and Digestive and Kidney Diseases, 1550 East Indian School Road, Phoenix, Arizona, 85014, USA
Ann Hum Genet 70:332-49. 2006..These methods may be useful in the analysis and interpretation of fine-mapping studies... - Prediction of diabetic nephropathy using urine proteomic profiling 10 years prior to development of nephropathyHasan H Otu
Genomics Center and DF HCC Cancer Proteomics Core, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
Diabetes Care 30:638-43. 2007..We examined whether proteomic technologies identify novel urine proteins associated with subsequent development of diabetic nephropathy in subjects with type 2 diabetes before evidence of microalbuminuria... - Depression, diabetes, and glycemic control in Pima IndiansPuneet K Singh
Diabetes Care 27:618-9. 2004 - Stability of body weight in type 2 diabetes: Response to Chaudhry et alHelen C Looker
Diabetes Care 29:1991. 2006