H C Looker

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Longitudinal studies of incidence and progression of diabetic retinopathy assessed by retinal photography in pima indians
    Helen C Looker
    Diabetes and Arthritis Epidemiology Section, National Institute of Diabetes and Digestive and Kidney Diseases, Phoenix, Arizona, USA
    Diabetes Care 26:320-6. 2003
  2. ncbi request reprint Gestational glucose tolerance and risk of type 2 diabetes in young Pima Indian offspring
    Paul W Franks
    Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Arizona, USA
    Diabetes 55:460-5. 2006
  3. pmc Childhood obesity, other cardiovascular risk factors, and premature death
    Paul W Franks
    Diabetes Epidemiology and Clinical Research Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, AZ, USA
    N Engl J Med 362:485-93. 2010
  4. ncbi request reprint Changes in BMI and weight before and after the development of type 2 diabetes
    H C Looker
    Diabetes and Arthritis Epidemiology Section, National Institute of Diabetes and Digestive and Kidney Diseases, Phoenix, Arizona 85014, USA
    Diabetes Care 24:1917-22. 2001
  5. ncbi request reprint Homocysteine as a risk factor for nephropathy and retinopathy in Type 2 diabetes
    H C Looker
    1550 E Indian School Road, Phoenix, Arizona 85014, USA
    Diabetologia 46:766-72. 2003
  6. ncbi request reprint Homocysteine and vitamin B(12) concentrations and mortality rates in type 2 diabetes
    Helen C Looker
    National Institute of Diabetes and Digestive and Kidney Diseases, Phoenix, AZ, USA
    Diabetes Metab Res Rev 23:193-201. 2007
  7. ncbi request reprint Adiponectin concentrations are influenced by renal function and diabetes duration in Pima Indians with type 2 diabetes
    Helen C Looker
    National Institute of Diabetes and Digestive and Kidney Diseases, Phoenix, Arizona 85014, USA
    J Clin Endocrinol Metab 89:4010-7. 2004
  8. ncbi request reprint Increasing incidence of proteinuria and declining incidence of end-stage renal disease in diabetic Pima Indians
    M E Pavkov
    Diabetes Epidemiology and Clinical Research Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona, USA
    Kidney Int 70:1840-6. 2006
  9. ncbi request reprint Do measures of body fat distribution provide information on the risk of type 2 diabetes in addition to measures of general obesity? Comparison of anthropometric predictors of type 2 diabetes in Pima Indians
    Marshall K Tulloch-Reid
    Diabetes and Arthritis Epidemiology Section, Phoenix Epidemiology and Clinical Research Branch, NIDDK National Institutes of Health, Phoenix, Arizona, USA
    Diabetes Care 26:2556-61. 2003
  10. ncbi request reprint Childhood predictors of young-onset type 2 diabetes
    Paul W Franks
    Diabetes Epidemiology and Clinical Research Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 1550 E Indian School Rd, Phoenix, AZ 85014, USA
    Diabetes 56:2964-72. 2007

Detail Information

Publications23

  1. ncbi request reprint Longitudinal studies of incidence and progression of diabetic retinopathy assessed by retinal photography in pima indians
    Helen C Looker
    Diabetes and Arthritis Epidemiology Section, National Institute of Diabetes and Digestive and Kidney Diseases, Phoenix, Arizona, USA
    Diabetes Care 26:320-6. 2003
    ..To examine incidence and progression of retinopathy using retinal photographs in Pima Indians and to compare the results with those obtained when retinopathy is assessed by direct ophthalmoscopy...
  2. ncbi request reprint Gestational glucose tolerance and risk of type 2 diabetes in young Pima Indian offspring
    Paul W Franks
    Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Arizona, USA
    Diabetes 55:460-5. 2006
    ..Thus, prevention of offspring type 2 diabetes may require strategies that focus on improving gestational glucose tolerance even within the normal range...
  3. pmc Childhood obesity, other cardiovascular risk factors, and premature death
    Paul W Franks
    Diabetes Epidemiology and Clinical Research Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, AZ, USA
    N Engl J Med 362:485-93. 2010
    ..The effect of childhood risk factors for cardiovascular disease on adult mortality is poorly understood...
  4. ncbi request reprint Changes in BMI and weight before and after the development of type 2 diabetes
    H C Looker
    Diabetes and Arthritis Epidemiology Section, National Institute of Diabetes and Digestive and Kidney Diseases, Phoenix, Arizona 85014, USA
    Diabetes Care 24:1917-22. 2001
    ..To examine weight changes occurring before and after the diagnosis of diabetes and the association of these changes with treatment and microvascular complications...
  5. ncbi request reprint Homocysteine as a risk factor for nephropathy and retinopathy in Type 2 diabetes
    H C Looker
    1550 E Indian School Road, Phoenix, Arizona 85014, USA
    Diabetologia 46:766-72. 2003
    ..The aim of this study was to examine the relation between serum total homocysteine concentrations and microvascular complications in Pima Indians with Type 2 diabetes...
  6. ncbi request reprint Homocysteine and vitamin B(12) concentrations and mortality rates in type 2 diabetes
    Helen C Looker
    National Institute of Diabetes and Digestive and Kidney Diseases, Phoenix, AZ, USA
    Diabetes Metab Res Rev 23:193-201. 2007
    ..To assess the role of homocysteine as a risk factor for mortality in diabetic subjects...
  7. ncbi request reprint Adiponectin concentrations are influenced by renal function and diabetes duration in Pima Indians with type 2 diabetes
    Helen C Looker
    National Institute of Diabetes and Digestive and Kidney Diseases, Phoenix, Arizona 85014, USA
    J Clin Endocrinol Metab 89:4010-7. 2004
    ..0001). Serum adiponectin is lowest in the presence of impaired glucose regulation and early diabetes. In the presence of diabetes, serum adiponectin is positively associated with abnormal renal function and diabetes duration...
  8. ncbi request reprint Increasing incidence of proteinuria and declining incidence of end-stage renal disease in diabetic Pima Indians
    M E Pavkov
    Diabetes Epidemiology and Clinical Research Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona, USA
    Kidney Int 70:1840-6. 2006
    ..On the other hand, the incidence of ESRD declined after 1990, coinciding with improved control of blood pressure, hyperglycemia, and perhaps other risk factors...
  9. ncbi request reprint Do measures of body fat distribution provide information on the risk of type 2 diabetes in addition to measures of general obesity? Comparison of anthropometric predictors of type 2 diabetes in Pima Indians
    Marshall K Tulloch-Reid
    Diabetes and Arthritis Epidemiology Section, Phoenix Epidemiology and Clinical Research Branch, NIDDK National Institutes of Health, Phoenix, Arizona, USA
    Diabetes Care 26:2556-61. 2003
    ....
  10. ncbi request reprint Childhood predictors of young-onset type 2 diabetes
    Paul W Franks
    Diabetes Epidemiology and Clinical Research Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 1550 E Indian School Rd, Phoenix, AZ 85014, USA
    Diabetes 56:2964-72. 2007
    ..Optimal prevention of young-onset type 2 diabetes requires identification of the early-life modifiable risk factors. We aimed to do this using longitudinal data in 1,604 5- to 19-year-old initially nondiabetic American Indians...
  11. ncbi request reprint Incidence of retinopathy and nephropathy in youth-onset compared with adult-onset type 2 diabetes
    Jonathan Krakoff
    National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona 85014, USA
    Diabetes Care 26:76-81. 2003
    ..To examine the risk of retinopathy and nephropathy in participants in whom type 2 diabetes was diagnosed in youth (before 20 years of age) compared with those in whom type 2 diabetes was diagnosed at older ages...
  12. ncbi request reprint Plasma glucose regulation and mortality in pima Indians
    Nan Hee Kim
    Diabetes Epidemiology and Clinical Research Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona 85014 4972, USA
    Diabetes Care 31:488-92. 2008
    ....
  13. ncbi request reprint Effect of periodontitis on overt nephropathy and end-stage renal disease in type 2 diabetes
    Wendy A Shultis
    Diabetes Epidemiology and Clinical Research Section, Phoenix Epidemiology and Clinical Research Branch, National Institutes of Health, 1550 E Indian School Rd, Phoenix, AZ 85014 4972, USA
    Diabetes Care 30:306-11. 2007
    ..The purpose of this study was to investigate the effect of periodontitis on development of overt nephropathy, defined as macroalbuminuria, and end-stage renal disease (ESRD) in type 2 diabetes...
  14. pmc Exploration of non-hierarchical classification methods combined with linkage analysis to identify loci influencing clusters of co-regulated transcripts
    Alka Malhotra
    Genetic Basis of Human Disease Division, Translational Genomics Research Institute, 445 North Fifth Street, Phoenix, Arizona 85004, USA
    BMC Proc 1:S48. 2007
    ....
  15. ncbi request reprint Early growth in offspring of diabetic mothers
    Leslie Touger
    Diabetes Epidemiology and Clinical Research Section, National Institute of Diabetes and Digestive and Kidney Diseases, 1550 E Indian School Rd, Phoenix, AZ 85014, USA
    Diabetes Care 28:585-9. 2005
    ..By age 5 years, offspring of diabetic mothers (ODMs) are heavier and have altered glucose metabolism compared with offspring of mothers without diabetes (non-DMs). This study evaluates the growth pattern of ODMs before the age of 5 years...
  16. ncbi request reprint Interaction between an 11betaHSD1 gene variant and birth era modifies the risk of hypertension in Pima Indians
    Paul W Franks
    Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 1550 E Indian School Rd, Phoenix, AZ 85014, USA
    Hypertension 44:681-8. 2004
    ..These data demonstrate association between genetic variability at 11betaHSD1 with hypertension, but these effects are modified by environmental factors...
  17. ncbi request reprint Genome-wide linkage analyses to identify Loci for diabetic retinopathy
    Helen C Looker
    PECRB, NIDDK, 1550 E Indian School Rd, Phoenix, AZ 85014, USA
    Diabetes 56:1160-6. 2007
    ..2 cM), whereas with multipoint analysis the peak LOD was 2.58 at 35 cM. No other areas of suggestive linkage were found. We propose that an area on chromosome 1 may harbor a gene or genes conferring susceptibility to diabetic retinopathy...
  18. ncbi request reprint Hematocrit and the incidence of type 2 diabetes in the pima indians
    Marshall K Tulloch-Reid
    Diabetes and Arthritis Epidemiology Section, Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 1550 East Indian School Rd, Phoenix, AZ 85014, USA
    Diabetes Care 27:2245-6. 2004
  19. pmc Depression, diabetes, and glycemic control in an American Indian community
    Puneet K C Sahota
    National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona 85014, USA
    J Clin Psychiatry 69:800-9. 2008
    ....
  20. ncbi request reprint Design and analysis of genetic association studies to finely map a locus identified by linkage analysis: sample size and power calculations
    R L Hanson
    Diabetes Epidemiology and Clinical Research Section, National Institute of Diabetes and Digestive and Kidney Diseases, 1550 East Indian School Road, Phoenix, Arizona, 85014, USA
    Ann Hum Genet 70:332-49. 2006
    ..These methods may be useful in the analysis and interpretation of fine-mapping studies...
  21. ncbi request reprint Prediction of diabetic nephropathy using urine proteomic profiling 10 years prior to development of nephropathy
    Hasan H Otu
    Genomics Center and DF HCC Cancer Proteomics Core, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
    Diabetes Care 30:638-43. 2007
    ..We examined whether proteomic technologies identify novel urine proteins associated with subsequent development of diabetic nephropathy in subjects with type 2 diabetes before evidence of microalbuminuria...
  22. ncbi request reprint Depression, diabetes, and glycemic control in Pima Indians
    Puneet K Singh
    Diabetes Care 27:618-9. 2004
  23. ncbi request reprint Stability of body weight in type 2 diabetes: Response to Chaudhry et al
    Helen C Looker
    Diabetes Care 29:1991. 2006