Maya Lodish

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc The differential diagnosis of familial lentiginosis syndromes
    Maya B Lodish
    Section on Endocrinology and Genetics, Program on Developmental Endocrinology Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, and Pediatric Endocrinology Inter Institute Training Program, National Institutes of Health, Building 10, CRC Room 1 3330, 10 Center Drive, MSC 1103, Bethesda, MD, 20892, USA
    Fam Cancer 10:481-90. 2011
  2. doi request reprint Germline PRKACA amplification causes variable phenotypes that may depend on the extent of the genomic defect: molecular mechanisms and clinical presentations
    Maya B Lodish
    Section on Endocrinology and GeneticsProgram on Developmental Endocrinology and Genetics, National Institute of Child Health and Human Development, National Institutes of Health, Building 10 CRC, Room 9D42, 10 Center Drive, MSc, 1103, Bethesda, Maryland 20892, USADepartment of Molecular and Human GeneticsBaylor College of Medicine, Houston, Texas, USADepartment of MedicineCedars Sinai Medical Center, Los Angeles, California, USADepartment of Clinical GeneticsGuy s Hospital, London, UKDepartment of EndocrinologyGreat Ormond Street Hospital for Children, London, UKDepartment of PediatricsOur Lady of the Lake Children s Hospital, Baton Rouge, Louisiana, USADepartment of PathologyNational Cancer Institute, Bethesda, Maryland, USAEmeritus MemberDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USADepartment of PediatricsBaylor College of Medicine, Houston, Texas, USATexas Children s HospitalHouston, Texas, USA
    Eur J Endocrinol 172:803-11. 2015
  3. pmc Skeletal maturation in children with Cushing syndrome is not consistently delayed: the role of corticotropin, obesity, and steroid hormones, and the effect of surgical cure
    Maya B Lodish
    Section on Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Md Electronic address
    J Pediatr 164:801-6. 2014
  4. pmc Clinical review: kinase inhibitors: adverse effects related to the endocrine system
    Maya B Lodish
    Section on Endocrinology and Genetics, Program on Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, and the Pediatric Endocrinology Inter Institute Training Program, National Institutes of Health, Bethesda, MD 20892, USA
    J Clin Endocrinol Metab 98:1333-42. 2013
  5. pmc Bone mineral density in children and young adults with neurofibromatosis type 1
    Maya B Lodish
    Section on Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA
    Endocr Relat Cancer 19:817-25. 2012
  6. pmc Known VDR polymorphisms are not associated with bone mineral density measures in pediatric Cushing disease
    Maya B Lodish
    Section on Endocrinology and Genetics, Program on Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA
    J Pediatr Endocrinol Metab 25:221-3. 2012
  7. pmc Recovery of the hypothalamic-pituitary-adrenal axis in children and adolescents after surgical cure of Cushing's disease
    Maya Lodish
    Section on Endocrinology and Genetics Program on Developmental Endocrinology and Genetics, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Clin Endocrinol Metab 97:1483-91. 2012
  8. pmc (111)In-octreotide scintigraphy for identification of metastatic medullary thyroid carcinoma in children and adolescents
    Maya Lodish
    Section on Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Clin Endocrinol Metab 97:E207-12. 2012
  9. pmc RET oncogene in MEN2, MEN2B, MTC and other forms of thyroid cancer
    Maya B Lodish
    Pediatric Endocrinology and Section on Endocrinology and Genetics, Program on Developmental Endocrinology and Genetics, Building 10, CRC, Room 1 3330, 10 Center Dr, MSC1103, Bethesda, MD 20892, USA
    Expert Rev Anticancer Ther 8:625-32. 2008
  10. pmc Rare and unusual endocrine cancer syndromes with mutated genes
    Maya B Lodish
    Section on Endocrinology Genetics, Program on Developmental Endocrinology Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, and Pediatric Endocrinology Inter Institute Training Program, National Institutes of Health, Bethesda, MD, USA
    Semin Oncol 37:680-90. 2010

Collaborators

Detail Information

Publications25

  1. pmc The differential diagnosis of familial lentiginosis syndromes
    Maya B Lodish
    Section on Endocrinology and Genetics, Program on Developmental Endocrinology Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, and Pediatric Endocrinology Inter Institute Training Program, National Institutes of Health, Building 10, CRC Room 1 3330, 10 Center Drive, MSC 1103, Bethesda, MD, 20892, USA
    Fam Cancer 10:481-90. 2011
    ..Recognition of cutaneous markers associated with these rare familial cancer syndromes provides the opportunity to pursue early surveillance for malignancies, as well as genetic counseling...
  2. doi request reprint Germline PRKACA amplification causes variable phenotypes that may depend on the extent of the genomic defect: molecular mechanisms and clinical presentations
    Maya B Lodish
    Section on Endocrinology and GeneticsProgram on Developmental Endocrinology and Genetics, National Institute of Child Health and Human Development, National Institutes of Health, Building 10 CRC, Room 9D42, 10 Center Drive, MSc, 1103, Bethesda, Maryland 20892, USADepartment of Molecular and Human GeneticsBaylor College of Medicine, Houston, Texas, USADepartment of MedicineCedars Sinai Medical Center, Los Angeles, California, USADepartment of Clinical GeneticsGuy s Hospital, London, UKDepartment of EndocrinologyGreat Ormond Street Hospital for Children, London, UKDepartment of PediatricsOur Lady of the Lake Children s Hospital, Baton Rouge, Louisiana, USADepartment of PathologyNational Cancer Institute, Bethesda, Maryland, USAEmeritus MemberDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USADepartment of PediatricsBaylor College of Medicine, Houston, Texas, USATexas Children s HospitalHouston, Texas, USA
    Eur J Endocrinol 172:803-11. 2015
    ..By doing new in-depth analysis of their cytogenetic abnormality, we attempted a better genotype-phenotype correlation of their PRKACA amplification...
  3. pmc Skeletal maturation in children with Cushing syndrome is not consistently delayed: the role of corticotropin, obesity, and steroid hormones, and the effect of surgical cure
    Maya B Lodish
    Section on Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Md Electronic address
    J Pediatr 164:801-6. 2014
    ..To assess skeletal maturity by measuring bone age (BA) in children with Cushing syndrome (CS) before and 1-year after transsphenoidal surgery or adrenalectomy, and to correlate BA with hormone levels and other measurements...
  4. pmc Clinical review: kinase inhibitors: adverse effects related to the endocrine system
    Maya B Lodish
    Section on Endocrinology and Genetics, Program on Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, and the Pediatric Endocrinology Inter Institute Training Program, National Institutes of Health, Bethesda, MD 20892, USA
    J Clin Endocrinol Metab 98:1333-42. 2013
    ..This review provides an update to the clinician regarding the management of potential endocrinological effects of KIs...
  5. pmc Bone mineral density in children and young adults with neurofibromatosis type 1
    Maya B Lodish
    Section on Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA
    Endocr Relat Cancer 19:817-25. 2012
    ..90; P=0.036). Plexiform neurofibroma burden was negatively correlated with LS BMAD (r(s)=-0.36, P=0.01). In pediatric and young adult patients with NF-1, LS BMAD was more severely affected than the FN BMAD or whole-body BMC/height...
  6. pmc Known VDR polymorphisms are not associated with bone mineral density measures in pediatric Cushing disease
    Maya B Lodish
    Section on Endocrinology and Genetics, Program on Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA
    J Pediatr Endocrinol Metab 25:221-3. 2012
    ..The data showed lack of association between BMD and these widely studied VDR polymorphisms, suggesting that the effect of endogenous hypercortisolism on bone in the context of CD does not depend on VDR genotypes...
  7. pmc Recovery of the hypothalamic-pituitary-adrenal axis in children and adolescents after surgical cure of Cushing's disease
    Maya Lodish
    Section on Endocrinology and Genetics Program on Developmental Endocrinology and Genetics, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Clin Endocrinol Metab 97:1483-91. 2012
    ..Recovery of the hypothalamic-pituitary-adrenal axis (HPAA) after transsphenoidal surgery (TSS) for Cushing's disease (CD) in children has not been adequately studied...
  8. pmc (111)In-octreotide scintigraphy for identification of metastatic medullary thyroid carcinoma in children and adolescents
    Maya Lodish
    Section on Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Clin Endocrinol Metab 97:E207-12. 2012
    ..Most medullary thyroid cancers (MTC) express somatostatin receptors; therefore, (111)In-octreotide somatostatin receptor scintigraphy (SRS) may be useful in detecting sites of metastases in children with MTC...
  9. pmc RET oncogene in MEN2, MEN2B, MTC and other forms of thyroid cancer
    Maya B Lodish
    Pediatric Endocrinology and Section on Endocrinology and Genetics, Program on Developmental Endocrinology and Genetics, Building 10, CRC, Room 1 3330, 10 Center Dr, MSC1103, Bethesda, MD 20892, USA
    Expert Rev Anticancer Ther 8:625-32. 2008
    ..This review will provide a brief overview of MTC and the associated RET oncogenic mutations, and will summarize the therapies designed to strategically interfere with the pathologic activation of the RET oncogene...
  10. pmc Rare and unusual endocrine cancer syndromes with mutated genes
    Maya B Lodish
    Section on Endocrinology Genetics, Program on Developmental Endocrinology Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, and Pediatric Endocrinology Inter Institute Training Program, National Institutes of Health, Bethesda, MD, USA
    Semin Oncol 37:680-90. 2010
    ..Recognition of the familial syndrome associated with a particular patient's endocrine tumor has important implications in terms of prognosis, screening of family members, and screening for associated conditions...
  11. pmc Blood pressure in pediatric patients with Cushing syndrome
    Maya B Lodish
    Section on Endocrinology Genetics, Program on Developmental Endocrinology Genetics, National Institute of Child Health and Human Development, NIH, Building 10, CRC, 10 Center Drive, MSC1103, Bethesda, Maryland 20892, USA
    J Clin Endocrinol Metab 94:2002-8. 2009
    ..Hypertension (HTN) has been reported in up to 60% of children with Cushing syndrome (CS), but its course, side effects, and potential differences among various causes of CS have not been adequately studied...
  12. pmc Reversible posterior encephalopathy syndrome associated with micronodular adrenocortical disease and Cushing syndrome
    Maya Lodish
    Section on Endocrinology and Genetics SEGEN and Pediatric Endocrinology Program, Program on Developmental Endocrinology and Genetics PDEGEN, National Institute of Child Health and Human Development NICHD, Building 10 CRC East, Room 1 3330, 10 Center Dr MSC 1103, Bethesda, MD 20892, USA
    Eur J Pediatr 169:125-6. 2010
    ....
  13. pmc Effects of Cushing disease on bone mineral density in a pediatric population
    Maya B Lodish
    Section on Endocrinology Genetics, Program on Developmental Endocrinology Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA
    J Pediatr 156:1001-5. 2010
    ..To evaluate bone mineral density (BMD) in children with Cushing disease before and after transphenoidal surgery (TSS)...
  14. pmc Intrauterine growth retardation associated with precocious puberty and sertoli cell hyperplasia
    M B Lodish
    Section on Endocrinology Genetics, Program on Developmental Endocrinology Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, and Pediatric Endocrinology Inter Institute Training Program, National Institutes of Health, Bethesda, MD, USA
    Horm Metab Res 42:682-8. 2010
    ..We conclude that in a patient with a Russell-Silver syndrome-like phenotype, Sertoli cell hyperplasia was associated with somatic trisomy 8, increased aromatization, and gonadotropin-independent precocious puberty...
  15. pmc Endocrine side effects of broad-acting kinase inhibitors
    Maya B Lodish
    Section on Endocrinology Genetics, Program on Developmental Endocrinology Genetics, Eunice Kennedy Shriver NICHD Pediatric Endocrinology Inter Institute Training Program, National Institutes of Health, 10 Center Drive, Bethesda, MD 20892, USA
    Endocr Relat Cancer 17:R233-44. 2010
    ..This review summarizes the most recent data on the endocrine side effects of TKIs...
  16. pmc Endocrine tumours in neurofibromatosis type 1, tuberous sclerosis and related syndromes
    Maya B Lodish
    Section on Endocrinology Genetics, Program on Developmental Endocrinology Genetics, Eunice Kennedy Shriver National Institute of Child Health and Paediatric Endocrinology Inter Institute Training Program, National Institutes of Health, Bethesda, MD 20892, USA
    Best Pract Res Clin Endocrinol Metab 24:439-49. 2010
    ..The discovery of mTOR inhibitors has led to a possible new therapeutic modality for patients with endocrine tumours as part of these familial syndromes...
  17. pmc Differences in adiposity in Cushing syndrome caused by PRKAR1A mutations: clues for the role of cyclic AMP signaling in obesity and diagnostic implications
    Edra London
    Section on Endocrinology and Genetics E L, A R, M L, E G, M K, C L, M d l L S, M N, C A S, Program on Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Inter Institute Pediatric Endocrinology Training Program E G, and Department of Diagnostic Radiology N P, C A S, Clinical Research Center, National Institutes of Health, Bethesda, Maryland 20892 and Service d Endocrinologie P├ędiatrique A R, Universite Paris Sud 11, Hopital Bicetre, 94270 Le Kremlin Bicetre, France
    J Clin Endocrinol Metab 99:E303-10. 2014
    ..Although CS is invariably associated with obesity, its different forms, including those associated with PKA defects, have not been compared...
  18. doi request reprint Multiple endocrine neoplasia type 2
    Maya Lodish
    Section on Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA lodishma mail nih gov
    Front Horm Res 41:16-29. 2013
    ..Recent guidelines released by the American Thyroid Association regarding the management of MTC will be summarized in this chapter...
  19. pmc Puberty and plexiform neurofibroma tumor growth in patients with neurofibromatosis type I
    Urania Dagalakis
    Section on Endocrinology and Genetics, Program on Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD
    J Pediatr 164:620-4. 2014
    ..To assess the relationship between pubertal progression and change in plexiform neurofibroma (PN) burden over time in pediatric and young adult patients with neurofibromatosis type 1 and PNs...
  20. pmc Is IGSF1 involved in human pituitary tumor formation?
    Fabio R Faucz
    Section on Endocrinology and GeneticsProgram on Developmental Endocrinology and Genetics PDEGEN Eunice Kennedy Shriver National Institute of Child Health and Human Development NICHD, National Institutes of Health, NIH Clinical Research Center, 10 Center Drive, Building 10, Room 1 3330, MSC1103, Bethesda, Maryland 20892, USAGroup for Advanced Molecular InvestigationGraduate Program in Health Science, Medical School, Pontificia Universidade Catolica do Parana, Curitiba 80215, BrazilDepartment of Pharmacology and TherapeuticsMcGill University, Montreal, Quebec, Canada H3G 1Y6Pediatric Endocrinology Inter institute Training ProgramEunice Kennedy Shriver National Institute of Child Health and Human Development NICHD, National Institutes of Health NIH, Bethesda, Maryland 20892, USAThe Liggins InstituteUniversity of Auckland, Auckland 1023, New ZealandTaranaki Base HospitalNew Plymouth 4310, New ZealandAuckland City Hospital and Greenlane Clinical CentreAuckland 1142, New ZealandDepartment of NeurosurgeryUniversity of Virginia Health Sciences Center, University of Virginia, Charlottesville, Virginia 22904, USASurgical Neurology BranchNational Institute for Neurological Diseases and Stroke NINDS, National Institutes of Health, Bethesda, Maryland 20892, USA Departments ofEndocrinology and Metabolic DisordersPediatricsLeiden University Medical Center, Leiden 2333, The Netherlands Section on Endocrinology and GeneticsProgram on Developmental Endocrinology and Genetics PDEGEN Eunice Kennedy Shriver National Institute of Child Health and Human Development NICHD, National Institutes of Health, NIH Clinical Research Center, 10 Center Drive, Building 10, Room 1 3330, MSC1103, Bethesda
    Endocr Relat Cancer 22:47-54. 2015
    ..Variations in IGSF1 expression in pituitary tissue in patients with or without IGSF1 germline mutations point to the need for further studies of IGSF1 action in pituitary adenoma formation. ..
  21. pmc Vandetanib in children and adolescents with multiple endocrine neoplasia type 2B associated medullary thyroid carcinoma
    Elizabeth Fox
    Division of Oncology, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
    Clin Cancer Res 19:4239-48. 2013
    ..Vandetanib, a VEGF and EGF receptor inhibitor, blocks RET tyrosine kinase activity and is active in adults with hereditary MTC...
  22. pmc Use of aromatase inhibitors in large cell calcifying sertoli cell tumors: effects on gynecomastia, growth velocity, and bone age
    Melissa K Crocker
    Section on Endocrinology and Genetics M K C, E G, M L, C A S, Program on Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institutes of Child Health and Human Development, National Institute of Health, Bethesda, Maryland 20892 Division of Endocrinology M K C, Boston Children s Hospital, Boston, Massachusetts 02115 and Division of Pediatric Endocrinology E G, Georgetown University, Washington, D C 20007
    J Clin Endocrinol Metab 99:E2673-80. 2014
    ..Prepubertal boys may present with growth acceleration, advanced bone age, and gynecomastia...
  23. ncbi request reprint Lack of mutations in the gene coding for the hGR (NR3C1) in a pediatric patient with ACTH-secreting pituitary adenoma, absence of stigmata of Cushing's syndrome and unusual histologic features
    George Briassoulis
    Section on Endocrinology and Genetics, Program on Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health NIH, Bethesda, MD 20892, USA
    J Pediatr Endocrinol Metab 25:213-9. 2012
    ..Rare cases of human glucocorticoid receptor (hGRalpha) (NR3C1) gene mutations have been described in the gemline or somatic state in Cushing's disease (CD)...
  24. doi request reprint Endocrine disorders in Fanconi anemia: recommendations for screening and treatment
    Anna Petryk
    Division of Pediatric Endocrinology A P, B N, University of Minnesota Masonic Children s Hospital, Minneapolis, Minnesota 55454 Department of Pediatrics R K S, Children s Hospital of Richmond at Virginia Commonwealth University, Richmond, Virginia 23229 Clinical Genetics Branch N G, B P A, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20850 Division of Endocrinology, Diabetes and Metabolism A N H, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215 Division of Endocrinology M M R, S R R, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio 45229 Pediatric Endocrinology Inter Institute Training Program M L, National Institutes of Health, Bethesda, Maryland 20892 and Section on Endocrinology and Genetics M L, C A S, Program on Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland 20892
    J Clin Endocrinol Metab 100:803-11. 2015
    ..The goal of this report is to provide an overview of endocrine abnormalities and guidelines for routine screening and treatment to allow early diagnosis and timely intervention...
  25. pmc Identification of novel genetic variants in phosphodiesterase 8B (PDE8B), a cAMP-specific phosphodiesterase highly expressed in the adrenal cortex, in a cohort of patients with adrenal tumours
    Anya Rothenbuhler
    Section on Endocrinology and Genetics and Pediatric Endocrinology Training Program, both at Program on Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892 1103, USA
    Clin Endocrinol (Oxf) 77:195-9. 2012
    ..Genetic aberrations in various components of cAMP signalling pathway predispose to endocrine tumours. Mutations in the phosphodiesterases (PDEs) are involved in the predisposition to adrenocortical neoplastic conditions...