Ying Liu

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Oligodendrocyte and astrocyte development in rodents: an in situ and immunohistological analysis during embryonic development
    Ying Liu
    Laboratory of Neurosciences, National Institute on Aging, Baltimore, Maryland 21224, USA
    Glia 40:25-43. 2002
  2. ncbi request reprint Glial progenitors in the CNS and possible lineage relationships among them
    Ying Liu
    Laboratory of Neurosciences, National Institute on Aging, Baltimore, MD 21224, USA
    Biol Cell 96:279-90. 2004
  3. ncbi request reprint CD44 expression identifies astrocyte-restricted precursor cells
    Ying Liu
    Laboratory of Neurosciences, Gerontology Research Center, National Institute on Aging, Baltimore, MD 21224, USA
    Dev Biol 276:31-46. 2004
  4. pmc Assessing self-renewal and differentiation in human embryonic stem cell lines
    Jingli Cai
    Laboratory of Neurosciences, National Institute on Aging, Department of Health and Human Services, Baltimore, Maryland, USA
    Stem Cells 24:516-30. 2006
  5. ncbi request reprint Massively parallel signature sequencing profiling of fetal human neural precursor cells
    Jingli Cai
    Stem Cell Biology Unit Laboratory of Neurosciences, National Institute on Aging Intramural Research Program, National Institutes of Health, Baltimore, MD 21224, USA
    Stem Cells Dev 15:232-44. 2006
  6. pmc Human Schwann cells retain essential phenotype characteristics after immortalization
    Helmar C Lehmann
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Stem Cells Dev 21:423-31. 2012
  7. pmc Cross-species transcriptional profiles establish a functional portrait of embryonic stem cells
    Yu Sun
    Bioinformatics Unit, Research Resources Branch, National Institute on Aging, National Institutes of Health, 333 Cassall Drive, Baltimore, MD 21224, USA
    Genomics 89:22-35. 2007
  8. pmc Genome wide profiling of human embryonic stem cells (hESCs), their derivatives and embryonal carcinoma cells to develop base profiles of U.S. Federal government approved hESC lines
    Ying Liu
    Laboratory of Neurosciences, National Institute on Aging Intramural Research Program, National Institutes of Health, Baltimore, Maryland 21224, USA
    BMC Dev Biol 6:20. 2006
  9. pmc Evolutionarily conserved transcriptional co-expression guiding embryonic stem cell differentiation
    Yu Sun
    Bioinformatics Unit, Research Resources Branch, National Institute on Aging, NIH, Baltimore, MD, USA
    PLoS ONE 3:e3406. 2008
  10. ncbi request reprint Microarray analysis of selected genes in neural stem and progenitor cells
    Yongquan Luo
    Laboratory of Neurosciences, Gerontology Research Center, National Institute on Aging, Room 4E02, 5600 Nathan Shock Drive, Baltimore, Maryland 21224, USA
    J Neurochem 83:1481-97. 2002

Collaborators

Detail Information

Publications73

  1. ncbi request reprint Oligodendrocyte and astrocyte development in rodents: an in situ and immunohistological analysis during embryonic development
    Ying Liu
    Laboratory of Neurosciences, National Institute on Aging, Baltimore, Maryland 21224, USA
    Glia 40:25-43. 2002
    ..A novel dorsal domain of CD44 immunoreactivity that can be distinguished from the more ventral glial precursor domains can be detected as early as E13.5...
  2. ncbi request reprint Glial progenitors in the CNS and possible lineage relationships among them
    Ying Liu
    Laboratory of Neurosciences, National Institute on Aging, Baltimore, MD 21224, USA
    Biol Cell 96:279-90. 2004
    ..We believe that the development of consensus sets of markers and an improvement in our ability to define stages of glial maturation will lead to a clearer appreciation of the importance of glia in the etiopathology of disease...
  3. ncbi request reprint CD44 expression identifies astrocyte-restricted precursor cells
    Ying Liu
    Laboratory of Neurosciences, Gerontology Research Center, National Institute on Aging, Baltimore, MD 21224, USA
    Dev Biol 276:31-46. 2004
    ..Misexpression of CD44 in culture inhibits oligodendrocytes and arrests cells at the precursor state. In summary, our data provide strong evidence for the existence of a CD44+ ARP in the developing nervous system...
  4. pmc Assessing self-renewal and differentiation in human embryonic stem cell lines
    Jingli Cai
    Laboratory of Neurosciences, National Institute on Aging, Department of Health and Human Services, Baltimore, Maryland, USA
    Stem Cells 24:516-30. 2006
    ..We show that qPCR, with as few as 12 selected genes, can reliably distinguish differentiated cells from undifferentiated hESC populations...
  5. ncbi request reprint Massively parallel signature sequencing profiling of fetal human neural precursor cells
    Jingli Cai
    Stem Cell Biology Unit Laboratory of Neurosciences, National Institute on Aging Intramural Research Program, National Institutes of Health, Baltimore, MD 21224, USA
    Stem Cells Dev 15:232-44. 2006
    ..In addition, our results allow us to identify novel genes expressed in fNPCs and provide a detailed profile of fNPCs...
  6. pmc Human Schwann cells retain essential phenotype characteristics after immortalization
    Helmar C Lehmann
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Stem Cells Dev 21:423-31. 2012
    ..These cells are particularly useful for drug screening and studies aimed at disease mechanisms involving SCs...
  7. pmc Cross-species transcriptional profiles establish a functional portrait of embryonic stem cells
    Yu Sun
    Bioinformatics Unit, Research Resources Branch, National Institute on Aging, National Institutes of Health, 333 Cassall Drive, Baltimore, MD 21224, USA
    Genomics 89:22-35. 2007
    ..The data and analyses resulting from this study provide a framework for new hypotheses and research directions and a public resource for functional genomics of ESCs...
  8. pmc Genome wide profiling of human embryonic stem cells (hESCs), their derivatives and embryonal carcinoma cells to develop base profiles of U.S. Federal government approved hESC lines
    Ying Liu
    Laboratory of Neurosciences, National Institute on Aging Intramural Research Program, National Institutes of Health, Baltimore, Maryland 21224, USA
    BMC Dev Biol 6:20. 2006
    ....
  9. pmc Evolutionarily conserved transcriptional co-expression guiding embryonic stem cell differentiation
    Yu Sun
    Bioinformatics Unit, Research Resources Branch, National Institute on Aging, NIH, Baltimore, MD, USA
    PLoS ONE 3:e3406. 2008
    ..Cross-species examination of transcriptional co-expression allows elucidation of fundamental and species-specific mechanisms regulating ESC self-renewal or differentiation...
  10. ncbi request reprint Microarray analysis of selected genes in neural stem and progenitor cells
    Yongquan Luo
    Laboratory of Neurosciences, Gerontology Research Center, National Institute on Aging, Room 4E02, 5600 Nathan Shock Drive, Baltimore, Maryland 21224, USA
    J Neurochem 83:1481-97. 2002
    ....
  11. ncbi request reprint Olig genes are expressed in a heterogeneous population of precursor cells in the developing spinal cord
    Ying Liu
    Laboratory of Neurosciences, National Institute on Aging, Baltimore, Maryland 21224, USA
    Glia 45:67-74. 2004
    ....
  12. pmc Negative regulation of TSHalpha target gene by thyroid hormone involves histone acetylation and corepressor complex dissociation
    Dongqing Wang
    Endocrinology Division, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA
    Mol Endocrinol 23:600-9. 2009
    ....
  13. ncbi request reprint BG01V: a variant human embryonic stem cell line which exhibits rapid growth after passaging and reliable dopaminergic differentiation
    Xianmin Zeng
    Cellular Neurobiology Branch, National Institute on Drug Abuse and NIH, DHHS, Baltimore, MD 21224, USA
    Restor Neurol Neurosci 22:421-8. 2004
    ..To explore a karyotypically abnormal variant human embryonic stem cell (hESC) line, BG01V, as a potential model for studies of dopaminergic neuronal differentiation...
  14. pmc Transcriptome coexpression map of human embryonic stem cells
    Huai Li
    Bioinformatics Unit, Branch of Research Resources, National Institute on Aging, NIH, Baltimore, MD 21224, USA
    BMC Genomics 7:103. 2006
    ..However, no systematic analysis has yet addressed whether gene expression in human ES cells may be regulated in chromosomal domains, and no chromosomal domains of coexpression have been identified...
  15. pmc An in vitro model of human dopaminergic neurons derived from embryonic stem cells: MPP+ toxicity and GDNF neuroprotection
    Xianmin Zeng
    Intramural Research Program IRP, Cellular Neurobiology Research Branch, Department of Health and Human Services DHHS, National Institute on Drug Abuse NIDA, National Institutes of Health NIH, Baltimore, MD, USA
    Neuropsychopharmacology 31:2708-15. 2006
    ....
  16. pmc Human embryonic stem cells have enhanced repair of multiple forms of DNA damage
    Scott Maynard
    Laboratory of Molecular Gerontology, National Institute on Aging, NIH, Box 1, 5600 Nathan Shock Drive, Baltimore, Maryland 21224 6825, USA
    Stem Cells 26:2266-74. 2008
    ..These data suggest that genomic maintenance pathways are enhanced in human embryonic stem cells, relative to differentiated human cells...
  17. pmc Passive (amyloid-β) immunotherapy attenuates monoaminergic axonal degeneration in the AβPPswe/PS1dE9 mice
    Ying Liu
    Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    J Alzheimers Dis 23:271-9. 2011
    ..Our results demonstrate that lowering of Aβ levels via passive Aβ immunotherapy ameliorates ongoing degenerative processes, supporting a causal link between Aβ and neurodegeneration...
  18. ncbi request reprint Transdifferentiation--fact or artifact
    Ying Liu
    Laboratory of Neurosciences, National Institute on Aging, 5600 Nathan Shock Drive, Baltimore, Maryland 21224, USA
    J Cell Biochem 88:29-40. 2003
    ..We predict, however, that transdifferentiation will not be reliable or reproducible and will probably require complex manipulations...
  19. ncbi request reprint Negative regulation of corticotropin releasing factor expression and limitation of stress response
    Greti Aguilera
    Section on Endocrine Physiology, Developmental Endocrinology Branch, National Institute of Child Health and Human Development, NIH, Bethesda, MD 20892 1103, USA
    Stress 10:153-61. 2007
    ..Rapid repression of CRF transcription following stress-induced activation is likely to contribute to limiting the stress response and to preventing disorders associated with excessive CRF production...
  20. ncbi request reprint Thyroid hormone action at the cellular, genomic and target gene levels
    Paul M Yen
    Department of Medicine, Johns Hopkins Bayview Medical Center, 4940 Eastern Avenue Rm B114, Baltimore, MD, USA
    Mol Cell Endocrinol 246:121-7. 2006
    ....
  21. ncbi request reprint Genomic alterations in cultured human embryonic stem cells
    Anirban Maitra
    McKusick Nathans Institute of Genetic Medicine, Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Nat Genet 37:1099-103. 2005
    ....
  22. pmc Endoplasmic reticulum stress is important for the manifestations of α-synucleinopathy in vivo
    Emanuela Colla
    Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    J Neurosci 32:3306-20. 2012
    ..Attenuating chronic ERS could be an effective therapy for PD and other α-synucleinopathies...
  23. pmc Stem cell myths
    Tim Magnus
    Stem Cell Section, Laboratory of Neurosciences, National Institute on Aging, NIH, 333 Cassell Drive, Room 406A, Baltimore, MD 21224, USA
    Philos Trans R Soc Lond B Biol Sci 363:9-22. 2008
    ..Data need to be collected and reported for failed as well as successful experiments and a rigorous scientific approach taken to evaluate the undeniable promise of stem cell biology...
  24. ncbi request reprint Thyroid hormone-regulated target genes have distinct patterns of coactivator recruitment and histone acetylation
    Ying Liu
    Endocrinology Division, Department of Medicine, Johns Hopkins Bayview Medical Center, 4940 Eastern Avenue, Room B114, Baltimore, Maryland 21224, USA
    Mol Endocrinol 20:483-90. 2006
    ..Our findings suggest that thyroid hormone-regulated target genes may have distinct patterns of coactivator recruitment and histone acetylation that may enable highly specific regulation...
  25. ncbi request reprint Growth arrest specific gene 1 acts as a region-specific mediator of the Fgf10/Fgf8 regulatory loop in the limb
    Ying Liu
    Department of Embryology, Carnegie Institution of Washington, Baltimore, Maryland 21210, USA
    Development 129:5289-300. 2002
    ..Our data provide evidence that Gas1 acts to maintain high levels of FGF10 at the tip mesenchyme and support the proposal that Fgf10 expression in this region is crucial for maintaining Fgf8 expression in the AER...
  26. ncbi request reprint Amyloid pathology is associated with progressive monoaminergic neurodegeneration in a transgenic mouse model of Alzheimer's disease
    Ying Liu
    Department of Pathology, Johns Hopkins University, Baltimore, Maryland 21205, USA
    J Neurosci 28:13805-14. 2008
    ..Our results show that a transgenic mouse model of Abeta pathology develops progressive MAergic neurodegeneration occurring in AD cases...
  27. pmc Suppression of Fas-FasL coexpression by erythropoietin mediates erythroblast expansion during the erythropoietic stress response in vivo
    Ying Liu
    Department of Pediatrics, University of Massachusetts Medical School, Worcester, MA 01605, USA
    Blood 108:123-33. 2006
    ..Therefore, Fas and FasL are negative regulators of erythropoiesis. Epo-mediated suppression of erythroblast Fas and FasL is a novel stress response pathway that facilitates erythroblast expansion in vivo...
  28. ncbi request reprint Expression of qBrn-1, a new member of the POU gene family, in the early developing nervous system and embryonic kidney
    Lei Lan
    The State Key Laboratory of Brain and Cognitive Sciences, Institute of Biophysics, The Chinese Academy of Sciences, Beijing 100101, People s Republic of China
    Dev Dyn 235:1107-14. 2006
    ..The distinct dynamic expression patterns of qBrn-1 and qBrn-2 indicate multiple roles of the class III POU genes in quail neurogenesis and organogenesis...
  29. pmc Human embryonic stem cells have a unique epigenetic signature
    Marina Bibikova
    Illumina, Inc, San Diego, California 92121, USA
    Genome Res 16:1075-83. 2006
    ..Our results indicate that hES cells have a unique epigenetic signature that may contribute to their developmental potential...
  30. ncbi request reprint Agmatine increases proliferation of cultured hippocampal progenitor cells and hippocampal neurogenesis in chronically stressed mice
    Yun Feng Li
    Beijing Institute of Pharmacology and Toxicology, Beijing 100850, China
    Acta Pharmacol Sin 27:1395-400. 2006
    ..To explore the mechanism of agmatine's antidepressant action...
  31. doi request reprint Isolation of neural stem and precursor cells from rodent tissue
    Yuanyuan Wu
    Department of Human Genetics, University of Utah, Salt Lake City, UT, USA
    Methods Mol Biol 438:39-53. 2008
    ....
  32. pmc Tlx1 and Tlx3 coordinate specification of dorsal horn pain-modulatory peptidergic neurons
    Yi Xu
    Dana Farber Cancer Institute and Department of Neurobiology, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Neurosci 28:4037-46. 2008
    ..These studies suggest that Tlx1 and Tlx3 operate high in the regulatory hierarchy that coordinates specification of dorsal horn pain-modulatory peptidergic neurons...
  33. pmc Cyclic adenosine 3',5'-monophosphate responsive element binding protein phosphorylation is required but not sufficient for activation of corticotropin-releasing hormone transcription
    Ying Liu
    Section on Endocrine Physiology, Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, 10 Center Drive, Bethesda, MD 20892, USA
    Endocrinology 149:3512-20. 2008
    ..In addition, the data indicate that phosphorylated CREB is essential but not sufficient for activation of CRH transcription, suggesting that full promoter stimulation requires the interaction of phosphorylated CREB with a coactivator...
  34. pmc Neuropathologies in transgenic mice expressing human immunodeficiency virus type 1 Tat protein under the regulation of the astrocyte-specific glial fibrillary acidic protein promoter and doxycycline
    Byung oh Kim
    Department of Microbiology and Immunology, The Walther Oncology Center, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Am J Pathol 162:1693-707. 2003
    ....
  35. pmc Protection against human immunodeficiency virus type 1 Tat neurotoxicity by Ginkgo biloba extract EGb 761 involving glial fibrillary acidic protein
    Wei Zou
    Department of Microbiology and Immunology, Indiana University School of Medicine, R2 302, 950 W Walnut St, Indianapolis, IN 46202, USA
    Am J Pathol 171:1923-35. 2007
    ....
  36. ncbi request reprint Qualification of embryonal carcinoma 2102Ep as a reference for human embryonic stem cell research
    Richard Josephson
    GlobalStem, Inc, 6 Taft Court, Rockville, Maryland 20850, USA
    Stem Cells 25:437-46. 2007
    ..On the basis of global gene and microRNA expression, 2102Ep is somewhat less similar to hESC than the alternatives; however, 2102Ep expresses more hESC-associated microRNAs than NTERA-2 does, and fewer markers of differentiated fates...
  37. ncbi request reprint Whole genome analysis of human neural stem cells derived from embryonic stem cells and stem and progenitor cells isolated from fetal tissue
    Soojung Shin
    Stem Cells and Regenerative Medicine, Invitrogen, Carlsbad, California, USA
    Stem Cells 25:1298-306. 2007
    ..Disclosure of potential conflicts of interest is found at the end of this article...
  38. ncbi request reprint Genome-wide atlas of gene expression in the adult mouse brain
    Ed S Lein
    Allen Institute for Brain Science, Seattle, Washington 98103, USA
    Nature 445:168-76. 2007
    ..This highly standardized atlas provides an open, primary data resource for a wide variety of further studies concerning brain organization and function...
  39. ncbi request reprint Brn3a-expressing retinal ganglion cells project specifically to thalamocortical and collicular visual pathways
    Lely A Quina
    Department of Psychiatry, University of California, San Diego, Veterans Affairs San Diego Healthcare System, La Jolla, California 92093 0603, USA
    J Neurosci 25:11595-604. 2005
    ..Brn3a is coexpressed extensively with the closely related factor Brn3b in the embryonic retina, and the effects of the loss of Brn3a in retinal development are not severe, suggesting partial redundancy of function in this gene class...
  40. ncbi request reprint Brg1 is required for murine neural stem cell maintenance and gliogenesis
    Steven Matsumoto
    Integrative Biosciences Department, School of Dentistry, Oregon Health and Science University, Portland, 97239, USA
    Dev Biol 289:372-83. 2006
    ....
  41. ncbi request reprint Neurogenin3 participates in gliogenesis in the developing vertebrate spinal cord
    Jeffrey Lee
    IGBMC, Universite Louis Pasteur, 1 rue Laurent Fries, BP10142, 67404 Illkirch Cedex, CU de Strasbourg, France
    Dev Biol 253:84-98. 2003
    ..Overall, the data suggest that Ngn3 may regulate glial differentiation at a developmental stage prior to the segregation of the oligodendrocyte and astrocyte lineage...
  42. pmc Endogenous Nkx2.2+/Olig2+ oligodendrocyte precursor cells fail to remyelinate the demyelinated adult rat spinal cord in the absence of astrocytes
    Jason F Talbott
    The MD PhD Program, University of Louisville, Louisville, KY 40292, USA
    Exp Neurol 192:11-24. 2005
    ..In vivo electrophysiology demonstrated a limited and unsustained functional recovery concurrent with endogenous remyelination following EB-induced lesions...
  43. ncbi request reprint Karyotypic stability, genotyping, differentiation, feeder-free maintenance, and gene expression sampling in three human embryonic stem cell lines derived prior to August 9, 2001
    Sandii N Brimble
    BresaGen, Inc, Athens, GA 30605, USA
    Stem Cells Dev 13:585-97. 2004
    ..BG01, BG02, and BG03 hESCs are therefore independent, undifferentiated, and pluripotent lines that can be maintained without accumulation of karyotypic abnormalities...
  44. ncbi request reprint Protein kinase A regulates cell cycle progression of mouse fertilized eggs by means of MPF
    Bingzhi Yu
    Department of Biochemical and Molecular Biology, China Medical University, Shenyang, Liaoning, People s Republic of China
    Dev Dyn 232:98-105. 2005
    ..Our results show that PKA, by inhibiting MPF, regulates cell cycle progression of fertilized eggs...
  45. ncbi request reprint Transplantation of glial-restricted precursor cells into the adult spinal cord: survival, glial-specific differentiation, and preferential migration in white matter
    Steve S W Han
    Department of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, Pennsylvania 19129, USA
    Glia 45:1-16. 2004
    ..GRP cell transplants may therefore provide a cellular transplant that can respond to appropriate endogenous cues to produce therapeutic molecules and new glial cells after injury...
  46. ncbi request reprint Astrocyte activation and dysfunction and neuron death by HIV-1 Tat expression in astrocytes
    Betty Y Zhou
    Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Mol Cell Neurosci 27:296-305. 2004
    ..In addition, these data suggest that astrocyte dysfunction contributes, at least in part, to Tat neurotoxicity and subsequently HIV-associated neuropathogenesis...
  47. ncbi request reprint Text mining functional keywords associated with genes
    Ying Liu
    College of Computing, Georgia Institute of Technology, Atlanta, GA 30332, USA
    Stud Health Technol Inform 107:292-6. 2004
    ..We feel that this approach is general enough to apply to medical and biological literature to find other relationships: drugs vs. genes, risk-factors vs. genes, etc...
  48. ncbi request reprint CD44 overexpression by oligodendrocytes: a novel mouse model of inflammation-independent demyelination and dysmyelination
    Therese M F Tuohy
    Division of Neuroscience, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton 97006, USA
    Glia 47:335-45. 2004
    ..These findings suggest that CNPase-CD44 mice are a novel model for noninflammatory progressive demyelinating disease and support a potential role for CD44 proteins expressed by glial cells in promoting demyelination...
  49. ncbi request reprint Induction of C chemokine XCL1 (lymphotactin/single C motif-1 alpha/activation-induced, T cell-derived and chemokine-related cytokine) expression by HIV-1 Tat protein
    Byung oh Kim
    Department of Microbiology and Immunology, Walther Oncology Center, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    J Immunol 172:1888-95. 2004
    ....
  50. ncbi request reprint Tip110, the human immunodeficiency virus type 1 (HIV-1) Tat-interacting protein of 110 kDa as a negative regulator of androgen receptor (AR) transcriptional activation
    Ying Liu
    Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    J Biol Chem 279:21766-73. 2004
    ..Taken together, these results indicate that Tip110 is a negative regulator of AR transcriptional activation, and may be directly involved in AR-related developmental, physiological, and pathological processes...
  51. ncbi request reprint Role of glucocorticoids and cAMP-mediated repression in limiting corticotropin-releasing hormone transcription during stress
    Jack D Shepard
    Section on Endocrine Physiology, Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20891, USA
    J Neurosci 25:4073-81. 2005
    ....
  52. ncbi request reprint The effects of a growth-inhibiting tripeptide, acetylGlu-Ser-GlyNH2 (Ac-ESG), on gene expression and cell cycle progression of two lymphoma cell lines
    Ying Liu
    Institute of Pediatric Research, National Hospital, University of Oslo, N 0027 Oslo, Norway
    Anticancer Res 23:3159-65. 2003
    ..In this paper we describe the effects of Ac-ESG on growth-related gene expression and cell cycle progression in two lymphoma cell lines, Ramos and Molt, representing B and T lymphocytes, respectively...
  53. ncbi request reprint Oligodendrocytes, GRPs and MNOPs
    Ying Liu
    Trends Neurosci 26:410-2. 2003
  54. ncbi request reprint Establishment of a new embryonic stem cell line derived from C57BL/6 mouse expressing EGFP ubiquitously
    Rie Shimizukawa
    Laboratory Animal Resource Center, University of Tsukuba, Tsukuba, Ibaraki, Japan
    Genesis 42:47-52. 2005
    ..The B6G-2 cell line is freely available from the BioResource Center, RIKEN Tsukuba Institute (http://www.brc.riken.jp/lab/cell/english/)...
  55. ncbi request reprint Zic1 represses Math1 expression via interactions with the Math1 enhancer and modulation of Math1 autoregulation
    Philip J Ebert
    Center for Basic Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX 75390 9111, USA
    Development 130:1949-59. 2003
    ..Zic1-mediated repression of Cath1 transcription may modulate the temporal switch between the progenitor state and differentiating dorsal cell types during neural tube development...
  56. ncbi request reprint Early ocular chemokine gene expression and leukocyte infiltration after high-risk corneal transplantation
    Satoru Yamagami
    Schepens Eye Research Institute, Harvard Medical School, Boston, MA, USA
    Mol Vis 11:632-40. 2005
    ..To determine the differential gene expression of chemokine species and leukocyte infiltration of grafts in the early pre-rejection postoperative period after high-risk (HR) compared to normal-risk (NR) corneal transplantation...
  57. ncbi request reprint [Screen selection of target genes regulated by HSF1 in heat shock response from myocardium of gene knockout mice]
    Ying Liu
    Department of Pathophysiology, Xiangya School of Medicine, Central South University, Changsha 410078, China
    Zhong Nan Da Xue Xue Bao Yi Xue Ban 29:1-5. 2004
    ..To screen select target genes regulated by heat shock transcription factor 1 (HSF1 ) in heat shock response from myocardium of HSF1 gene knockout mice using cDNA chip...
  58. ncbi request reprint Hyaluronan accumulates in demyelinated lesions and inhibits oligodendrocyte progenitor maturation
    Stephen A Back
    Department of Pediatrics, School of Medicine, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, Oregon 97239, USA
    Nat Med 11:966-72. 2005
    ..HMW hyaluronan may therefore contribute substantially to remyelination failure by preventing the maturation of OPCs that are recruited to demyelinating lesions...
  59. ncbi request reprint Hes1 but not Hes5 regulates an astrocyte versus oligodendrocyte fate choice in glial restricted precursors
    Yuanyuan Wu
    Department of Neurobiology and Anatomy, University of Utah School of Medicine, Salt Lake City, Utah, USA
    Dev Dyn 226:675-89. 2003
    ..Overexpression of Notch1 has an effect on gliogenesis similar to that of Hes1 and the mRNA levels of Hes1 are up-regulated in cells overexpressing Notch1, suggesting that Notch1 could be an upstream activator of Hes1...
  60. ncbi request reprint Transgenic analysis of the stem cell leukemia +19 stem cell enhancer in adult and embryonic hematopoietic and endothelial cells
    Lev Silberstein
    Department of Hematology, Cambridge Institute for Medical Research, Cambridge University, Hills Road, Cambridge CB2 2XY, UK
    Stem Cells 23:1378-88. 2005
    ..Moreover, activity in a proportion of thymocytes and other SCL-negative cell types suggests the existence of a silencer elsewhere in the SCL locus...
  61. ncbi request reprint Rac-GAP-dependent inhibition of breast cancer cell proliferation by {beta}2-chimerin
    Chengfeng Yang
    Department of Pharmacology, University of Pennsylvania, Philadelphia, Pennsylvania 19104 6160, USA
    J Biol Chem 280:24363-70. 2005
    ....
  62. ncbi request reprint Distinct activities of Msx1 and Msx3 in dorsal neural tube development
    Ying Liu
    Center for Basic Neuroscience, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
    Development 131:1017-28. 2004
    ..Taken together, these results suggest that these two different Msx family members can mediate distinct aspects of Bmp signaling during neural tube development...
  63. ncbi request reprint Nutritional genomics in yeast models
    Ying Liu
    Institute of Human Nutrition, Department of Pediatrics, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    Nutrition 20:166-72. 2004
  64. ncbi request reprint Cortical spreading depression affects Fos expression in the hypothalamic paraventricular nucleus and the cerebral cortex of both hemispheres
    Golam Mohammad Iqbal Chowdhury
    Department of Neuroscience, Yamaguchi University School of Medicine, Ube, Yamaguchi 755 8505, Japan
    Neurosci Res 45:149-55. 2003
    ..These results suggest that in addition to the ipsilateral cortex, CoSD affects Fos expression exclusively in the PVN and the contralateral cortex...
  65. ncbi request reprint KLF4 regulates the expression of interleukin-10 in RAW264.7 macrophages
    Junwen Liu
    Laboratory of Shock, Department of Pathophysiology, Xiangya School of Medicine, Central South University, 110 Xiangya Road, Changsha, Hunan 410008, People s Republic of China
    Biochem Biophys Res Commun 362:575-81. 2007
    ..The overexpression of KLF4 promoted the transcription and DNA binding activities of KLF4 to the IL-10 promoter. These results indicate that KLF4 plays an important role in regulating the expression of IL-10...
  66. ncbi request reprint Physical and transcript map of the region between D6S264 and D6S149 on chromosome 6q27, the minimal region of allele loss in sporadic epithelial ovarian cancer
    Ying Liu
    ICRF Molecular Oncology Laboratories, John Radcliffe Hospital, Headington, Oxford, OX3 9DS, UK
    Oncogene 21:387-99. 2002
    ..Clonogenic assays were performed by transfecting the full-length gene in to ovarian cancer cell lines and no suppression of growth was observed...
  67. ncbi request reprint Modeling nonlinearity in dilution design microarray data
    Xiuwen Zheng
    Department of Mathematical Sciences, University of Texas at Dallas, Richardson, TX 75083 0688, USA
    Bioinformatics 23:1339-47. 2007
    ..Furthermore, a new adjusted fold change (adj-FC) was proposed to predict the true FC without nonlinearity, in particular for large FC...
  68. pmc The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements
    Leming Shi
    National Center for Toxicological Research, US Food and Drug Administration, Jefferson, Arkansas 72079, USA
    Nat Biotechnol 24:1151-61. 2006
    ..This study provides a resource that represents an important first step toward establishing a framework for the use of microarrays in clinical and regulatory settings...
  69. pmc A molecular scheme for improved characterization of human embryonic stem cell lines
    Richard Josephson
    Stem Cell Center, American Type Culture Collection ATCC, Manassas, VA, USA
    BMC Biol 4:28. 2006
    ..However, hESC must be routinely analyzed at the genomic level to guard against deleterious changes during extensive propagation, expansion, and manipulation in vitro...
  70. ncbi request reprint Global genomic approaches to the iron-regulated proteome
    Ying Liu
    Department of Laboratory Medicine and Pathobiology, Medical Sciences Building Rm 6302, University of Toronto, 1 King s College Circle, Toronto M5S 1A8, Canada
    Ann Clin Lab Sci 35:230-9. 2005
    ..We conclude that definitive understanding of the complex iron-regulated proteome requires global gene approaches and rigorous interlaboratory standardization...
  71. ncbi request reprint Localization of putative stem cells and four cell populations with different differentiation degree in mouse mammary anlagen
    Jianyong Han
    State Key Laboratory of Agrobiotecnology, China Agricultural University, Beijing, China
    Histochem Cell Biol 126:35-43. 2006
    ..The results indicate that the putative stem cells are localized near the edge of the mammary anlagen; the cell populations with different differentiation degree were localized in the central part and around the edge within the anlagen...
  72. pmc Analysis of P53 mutations and their expression in 56 colorectal cancer cell lines
    Ying Liu
    Cancer Research UK Cancer and Immunogenetics Laboratory, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Oxford OX3 9DS, UK
    Proc Natl Acad Sci U S A 103:976-81. 2006
    ....
  73. ncbi request reprint Characterization of a new NIH-registered variant human embryonic stem cell line, BG01V: a tool for human embryonic stem cell research
    Todd W Plaia
    Stem Cell Center, American Type Culture Collection, 10801 University Boulevard, Manassas, Virginia 20110, USA
    Stem Cells 24:531-46. 2006
    ....