Xunxian Liu

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Dehydroepiandrosterone administration or G{alpha}q overexpression induces {beta}-catenin/T-Cell factor signaling and growth via increasing association of estrogen receptor-{beta}/Dishevelled2 in androgen-independent prostate cancer cells
    Xunxian Liu
    Endocrine Section, Laboratory of Clinical Investigation, National Center for Complementary and Alternative Medicine, National Institutes of Health, Bethesda, Maryland 20892, USA
    Endocrinology 151:1428-40. 2010
  2. pmc Natural Functions of PLIN2 Mediating Wnt/LiCl Signaling and Glycogen Synthase Kinase 3 (GSK3)/GSK3 Substrate-Related Effects Are Modulated by Lipid
    Xunxian Liu
    Intramural Research Programs, National Center for Complementary and Integrative Health, National Institutes of Health, Bethesda, Maryland, USA
    Mol Cell Biol 36:421-37. 2015
  3. pmc Androgen-induced PSA expression requires not only activation of AR but also endogenous IGF-I or IGF-I/PI3K/Akt signaling in human prostate cancer epithelial cells
    Xunxian Liu
    Endocrine Section, Laboratory of Clinical Investigation, Division of Intramural Research, National Center for Complementary and Alternative Medicine, National Institutes of Health, Bethesda, Maryland 20892 1547, USA
    Prostate 71:766-77. 2011
  4. pmc Transforming growth factor β1 increase of hydroxysteroid dehydrogenase proteins is partly suppressed by red clover isoflavones in human primary prostate cancer-derived stromal cells
    Xunxian Liu
    Endocrine Section, Intramural Research Program, National Center for Complementary and Alternative Medicine, National Institutes of Health, U S Department of Health and Human Services, Bethesda, MD 20892, USA
    Carcinogenesis 32:1648-54. 2011
  5. ncbi request reprint Androgen receptor or estrogen receptor-beta blockade alters DHEA-, DHT-, and E(2)-induced proliferation and PSA production in human prostate cancer cells
    Julia T Arnold
    Endocrine Section, Laboratory of Clinical Investigation, Division of Intramural Research, National Center for Complementary and Alternative Medicine, National Institutes of Health, Bethesda, Maryland 20892 0933, USA
    Prostate 67:1152-62. 2007
  6. pmc Endocrine-immune-paracrine interactions in prostate cells as targeted by phytomedicines
    Nora E Gray
    Endocrine Section, Laboratory of Clinical Investigation, Division of Intramural Research, National Center for Complementary and Alternative Medicine, NIH, Bethesda, Maryland, USA
    Cancer Prev Res (Phila) 2:134-42. 2009
  7. doi request reprint Lycopene inhibits IGF-I signal transduction and growth in normal prostate epithelial cells by decreasing DHT-modulated IGF-I production in co-cultured reactive stromal cells
    Xunxian Liu
    Endocrine Section, Laboratory of Clinical Investigation, Division of Intramural Research, National Center for Complementary and Alternative Medicine, National Institutes of Health, Bethesda, MD 20892, USA
    Carcinogenesis 29:816-23. 2008
  8. ncbi request reprint Rapid, Wnt-induced changes in GSK3beta associations that regulate beta-catenin stabilization are mediated by Galpha proteins
    Xunxian Liu
    Laboratory of Cellular and Developmental Biology, NIDDK, National Institutes of Health, Bethesda, Maryland 20892, USA
    Curr Biol 15:1989-97. 2005

Detail Information

Publications8

  1. pmc Dehydroepiandrosterone administration or G{alpha}q overexpression induces {beta}-catenin/T-Cell factor signaling and growth via increasing association of estrogen receptor-{beta}/Dishevelled2 in androgen-independent prostate cancer cells
    Xunxian Liu
    Endocrine Section, Laboratory of Clinical Investigation, National Center for Complementary and Alternative Medicine, National Institutes of Health, Bethesda, Maryland 20892, USA
    Endocrinology 151:1428-40. 2010
    ..Although DHEA may enhance PrCa cell growth via androgenic or estrogenic pathways, the effects of DHEA administration on clinical prostate function remain to be determined...
  2. pmc Natural Functions of PLIN2 Mediating Wnt/LiCl Signaling and Glycogen Synthase Kinase 3 (GSK3)/GSK3 Substrate-Related Effects Are Modulated by Lipid
    Xunxian Liu
    Intramural Research Programs, National Center for Complementary and Integrative Health, National Institutes of Health, Bethesda, Maryland, USA
    Mol Cell Biol 36:421-37. 2015
    ....
  3. pmc Androgen-induced PSA expression requires not only activation of AR but also endogenous IGF-I or IGF-I/PI3K/Akt signaling in human prostate cancer epithelial cells
    Xunxian Liu
    Endocrine Section, Laboratory of Clinical Investigation, Division of Intramural Research, National Center for Complementary and Alternative Medicine, National Institutes of Health, Bethesda, Maryland 20892 1547, USA
    Prostate 71:766-77. 2011
    ..Although activated AR is required for androgen-induction of expression of both genes, effects of the IGF-I signaling pathways on the androgen-induction of PSA have not been studied...
  4. pmc Transforming growth factor β1 increase of hydroxysteroid dehydrogenase proteins is partly suppressed by red clover isoflavones in human primary prostate cancer-derived stromal cells
    Xunxian Liu
    Endocrine Section, Intramural Research Program, National Center for Complementary and Alternative Medicine, National Institutes of Health, U S Department of Health and Human Services, Bethesda, MD 20892, USA
    Carcinogenesis 32:1648-54. 2011
    ..These data suggest a pathway connecting overproduction of TGFβ with increased PSA in prostate cancer...
  5. ncbi request reprint Androgen receptor or estrogen receptor-beta blockade alters DHEA-, DHT-, and E(2)-induced proliferation and PSA production in human prostate cancer cells
    Julia T Arnold
    Endocrine Section, Laboratory of Clinical Investigation, Division of Intramural Research, National Center for Complementary and Alternative Medicine, National Institutes of Health, Bethesda, Maryland 20892 0933, USA
    Prostate 67:1152-62. 2007
    ..LNCaP and LAPC-4 prostate cancer cells were used to determine whether DHEA-modulated proliferation and prostate specific antigen (PSA) production were mediated via the androgen receptor (AR) and/or ERbeta...
  6. pmc Endocrine-immune-paracrine interactions in prostate cells as targeted by phytomedicines
    Nora E Gray
    Endocrine Section, Laboratory of Clinical Investigation, Division of Intramural Research, National Center for Complementary and Alternative Medicine, NIH, Bethesda, Maryland, USA
    Cancer Prev Res (Phila) 2:134-42. 2009
    ....
  7. doi request reprint Lycopene inhibits IGF-I signal transduction and growth in normal prostate epithelial cells by decreasing DHT-modulated IGF-I production in co-cultured reactive stromal cells
    Xunxian Liu
    Endocrine Section, Laboratory of Clinical Investigation, Division of Intramural Research, National Center for Complementary and Alternative Medicine, National Institutes of Health, Bethesda, MD 20892, USA
    Carcinogenesis 29:816-23. 2008
    ..This study expands the understanding of the preventive mechanisms of lycopene in prostate cancer...
  8. ncbi request reprint Rapid, Wnt-induced changes in GSK3beta associations that regulate beta-catenin stabilization are mediated by Galpha proteins
    Xunxian Liu
    Laboratory of Cellular and Developmental Biology, NIDDK, National Institutes of Health, Bethesda, Maryland 20892, USA
    Curr Biol 15:1989-97. 2005
    ..Yet, the mechanisms that underlie Wnt regulation of GSK3 and stabilization of beta-catenin are still not fully appreciated...