Research Topics
Species | Andrew H LiuSummaryAffiliation: National Jewish Medical and Research Center Country: USA Publications
Research Grants
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Detail Information
Publications
Innate microbial sensors and their relevance to allergyAndrew H Liu
Pediatric Allergy and Immunology, National Jewish Health, Denver, CO 80206, USA
J Allergy Clin Immunol 122:846-58; quiz 858-60. 2008....
Something old, something new: indoor endotoxin, allergens and asthmaAndrew H Liu
Division of Pediatric Allergy and Immunology, National Jewish Medical and Research Center, Denver, CO 80206, USA
Paediatr Respir Rev 5:S65-71. 2004..These observations, consistent with the "Hygiene Hypothesis" of allergy and asthma, are an encouraging glimpse of the potential for early immune modulatory approaches to asthma therapy and prevention...- Treatment of asthma with anti-immunoglobulin E monoclonal antibodyAndrew H Liu
Division of Pediatric Allergy and Clinical Immunology, National Jewish Medical and Research Center, University of Colorado School of Medicine, Denver, Colorado 80206, USA
Allergy Asthma Proc 27:S24-8. 2006..There is good reason to have increasing comfort with omalizumab therapeutic trials, especially in those with severe asthma... - Development and cross-sectional validation of the Childhood Asthma Control TestAndrew H Liu
National Jewish Medical and Research Center and the University of Colorado School of Medicine, Denver, CO 80206, USA
J Allergy Clin Immunol 119:817-25. 2007..For children younger than 12 years old with asthma, there are several quality-of-life instruments, clinical diaries, and questionnaires assessing symptoms; however, a validated tool for assessing asthma control is currently lacking... - Hygiene theory and allergy and asthma preventionAndrew H Liu
Division of Allergy and Clinical Immunology, Department of Pediatrics, National Jewish Medical and Research Center, University of Colorado School of Medicine, Denver, CO 80206, USA
Paediatr Perinat Epidemiol 21:2-7. 2007.... - Short-term impact of a randomized multifaceted intervention for wheezing infants in low-income familiesMary D Klinnert
National Jewish Medical and Research Center, University of Colorado Health Sciences Center, Denver 80206, USA
Arch Pediatr Adolesc Med 159:75-82. 2005..To present an interim analysis of the effect of a home-based intervention with low-income caregivers of wheezing infants at risk for childhood asthma on mediating variables... - The natural history of milk allergy in an observational cohortRobert A Wood
Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA
J Allergy Clin Immunol 131:805-12. 2013..There are few studies on the natural history of milk allergy. Most are single-site and not longitudinal, and these have not identified a means for early prediction of outcomes... 
Sublingual immunotherapy for peanut allergy: a randomized, double-blind, placebo-controlled multicenter trialDavid M Fleischer
Department of Pediatrics, National Jewish Health, Denver, CO 80206, USA
J Allergy Clin Immunol 131:119-27.e1-7. 2013..There are presently no available therapeutic options for patients with peanut allergy...- Characterization of endotoxin and mouse allergen exposures in mouse facilities and research laboratoriesKarin A Pacheco
Department of Medicine, National Jewish Medical and Research Center, Denver, CO, USA
Ann Occup Hyg 50:563-72. 2006..Endotoxin and mouse allergen are derived from the same animal source, but have different physicochemical attributes. It is not known if airborne exposures to these agents are correlated in the laboratory animal workplace... - Effect of animal contact and microbial exposures on the prevalence of atopy and asthma in urban vs rural children in IndiaPudupakkam K Vedanthan
University of Colorado Health Sciences Center, Denver, USA
Ann Allergy Asthma Immunol 96:571-8. 2006..Environmental factors, including microbial exposures and close animal contact, are implicated in the lower prevalence of asthma and allergy in rural vs urban children... - Morbidity patterns among low-income wheezing infantsMary D Klinnert
Department of Pediatrics, National Jewish Medical and Research Center, Denver, Colorado 80206, USA
Pediatrics 112:49-57. 2003..This study describes morbidity attributable to wheezing illness in a multi-ethnic sample of low-income infants younger than age 2, and examines biological, environmental, and psychosocial correlates of morbidity indexes... - Outcome of a randomized multifaceted intervention with low-income families of wheezing infantsMary D Klinnert
Department of Pediatrics, National Jewish Medical and Research Center, 1400 Jackson St, G320, Denver, CO 80206, USA
Arch Pediatr Adolesc Med 161:783-90. 2007..To evaluate the outcome of a secondary intervention conducted with infants at risk for asthma... - Bacterial DNA in house and farm barn dustSitesh R Roy
Division of Pediatric Allergy and Immunology, National Jewish Medical and Research Center, and the Department of Pediatrics, University of Colorado Health Sciences Center, 1400 Jackson Street, Denver, CO 80206, USA
J Allergy Clin Immunol 112:571-8. 2003..DNA from farm barn dust augments the immune modulatory effects of endotoxin and may combine with exposure to other such naturally occurring microbial components to mitigate allergy and asthma development... - Oral immunotherapy for treatment of egg allergy in childrenA Wesley Burks
Department of Pediatrics, Duke University Medical Center, Durham, NC 27599 7220, USA
N Engl J Med 367:233-43. 2012..For egg allergy, dietary avoidance is the only currently approved treatment. We evaluated oral immunotherapy using egg-white powder for the treatment of children with egg allergy... - National prevalence and risk factors for food allergy and relationship to asthma: results from the National Health and Nutrition Examination Survey 2005-2006Andrew H Liu
National Jewish Health and University of Colorado Denver School of Medicine, Denver, CO, USA
J Allergy Clin Immunol 126:798-806.e13. 2010..The national prevalence and patterns of food allergy (FA) in the United States are not well understood... - Asthma outcomes: biomarkersStanley J Szefler
National Jewish Health, Denver, Colorado, USA
J Allergy Clin Immunol 129:S9-23. 2012..Measurement of biomarkers has been incorporated within clinical research studies of asthma to characterize the population and associate the disease with environmental and therapeutic effects... - Importance of the personal endotoxin cloud in school-age children with asthmaNathan Rabinovitch
Department of Pediatrics, National Jewish Medical and Research Center, 1400 Jackson St, Denver, CO 80206, USA
J Allergy Clin Immunol 116:1053-7. 2005.... - Optimizing childhood asthma management: the role of national institutes of health-sponsored study groupsAndrew H Liu
Department of Pediatric, Division of Allergy and Immunology, National Jewish Medical and Research Center, University of Colorado Health Sciences Center, Denver, Colorado 80206, USA
Allergy Asthma Proc 25:365-9. 2004.... - Neutrophilic airway inflammation and association with bacterial lipopolysaccharide in children with asthma and wheezingPia J Hauk
Department of Pediatrics, National Jewish Medical and Research Center, Denver, Colorado 80206, USA
Pediatr Pulmonol 43:916-23. 2008.... - Unraveling the ecology of risks for early childhood asthma among ethnically diverse families in the southwestMary D Klinnert
National Jewish Medical and Research Center, Denver, Colo 80206, USA
Am J Public Health 92:792-8. 2002..We describe the prevalence of asthma risk factors within racial/ethnic and language groups of infants participating in an intervention study for reducing chronic asthma... - Immunologic features of infants with milk or egg allergy enrolled in an observational study (Consortium of Food Allergy Research) of food allergyScott H Sicherer
Elliot and Roslyn Jaffe Food Allergy Institute, Division of Allergy and Immunology, Department of Pediatrics, Mount Sinai School of Medicine, New York, NY 10029 6574, USA
J Allergy Clin Immunol 125:1077-1083.e8. 2010..Immune features of infants with food allergy have not been delineated... - The Childhood Asthma Control Test: retrospective determination and clinical validation of a cut point to identify children with very poorly controlled asthmaAndrew H Liu
National Jewish Health and University of Colorado School of Medicine, Pediatrics Allergy and Immunology, Denver, CO 80206 2762, USA
J Allergy Clin Immunol 126:267-73, 273.e1. 2010..However, new asthma management guidelines distinguish 3 levels of asthma control... - Impulse oscillometry provides an effective measure of lung dysfunction in 4-year-old children at risk for persistent asthmaAlex Marotta
Division of Pediatric Allergy and Immunology, National Jewish Medical and Research Center, and the Department of Pediatrics, University of Colorado Health Sciences Center, Denver, 80206, USA
J Allergy Clin Immunol 112:317-22. 2003..IOS is a useful diagnostic tool in early asthma development and might be a helpful objective outcome measure of early interventions... - Predictors of remitting, periodic, and persistent childhood asthmaRonina A Covar
National Jewish Health, Denver, CO 80206, USA
J Allergy Clin Immunol 125:359-366.e3. 2010..The course of mild to moderate persistent asthma in children is not clearly established... - Management of asthma based on exhaled nitric oxide in addition to guideline-based treatment for inner-city adolescents and young adults: a randomised controlled trialStanley J Szefler
National Jewish Health, Denver, CO, USA
Lancet 372:1065-72. 2008.... - Mediator release assay for assessment of biological potency of German cockroach allergen extractsAnna H Nowak-Wegrzyn
Division of Pediatric Allergy and Immunology, Mount Sinai School of Medicine, New York, NY 10029, USA
J Allergy Clin Immunol 123:949-955.e1. 2009..Cockroach is an important allergen in inner-city asthma. The diagnosis and treatment of cockroach allergy has been impeded by the lack of standardized cockroach extracts... - Successful school-based intervention for inner-city children with persistent asthmaMark E Anderson
Department of Community Health Services, Denver Health, Denver, Colorado 80204, USA
J Asthma 41:445-53. 2004..This study sought to determine the impact of the Kunsberg program on asthma utilization... - Metropolitan endotoxin exposure, allergy and asthmaBenjamin J Song
Division of Pediatric Allergy and Immunology, National Jewish Medical Center, Denver, Colorado 80206, USA
Curr Opin Allergy Clin Immunol 3:331-5. 2003.... - Consider the child: how early should we treat?Andrew H Liu
Department of Pediatrics, National Jewish Medical and Research Center, and University of Colorado Health Sciences Center, Denver, Colorado 80206, USA
J Allergy Clin Immunol 113:S19-24. 2004..This review will discuss recent clinical studies that exemplify early intervention and prevention strategies... - Status of asthma control in pediatric primary care: results from the pediatric Asthma Control Characteristics and Prevalence Survey Study (ACCESS)Andrew H Liu
Department of Pediatrics, National Jewish Health and University of Colorado Denver School of Medicine, Denver, CO, USA
J Pediatr 157:276-281.e3. 2010..To estimate the prevalence of uncontrolled asthma in pediatric patients with asthma visiting their primary care provider for any medical reason... - Airborne endotoxin predicts symptoms in non-mouse-sensitized technicians and research scientists exposed to laboratory miceKarin A Pacheco
Department of Medicine, Division of Environmental and Occupational Health Sciences, National Jewish Medical and Research Center, 1400 Jackson Street, Denver, CO 80206, USA
Am J Respir Crit Care Med 167:983-90. 2003..8, p = 0.003). We conclude that airborne endotoxin is associated with respiratory symptoms to mice in non-mouse-sensitized scientists and technicians... - Overcoming childhood asthma disparities of the inner-city poorMonica J Federico
Division of Pediatric Pulmonary, The Children s Hospital, 1056 East 19th Avenue, Denver, CO 80262 USA
Pediatr Clin North Am 50:655-75, vii. 2003..It is hoped that these efforts will limit the severe consequences of asthma, narrow disparities in outcomes, and substantially reduce medical expenditures for asthma... - Hygiene hypothesis: fact or fiction?Andrew H Liu
Division of Pediatric Allergy and Immunology, National Jewish Medical and Research Center, and the Department of Pediatrics, University of Colorado Health Sciences Center, Denver 80206, USA
J Allergy Clin Immunol 111:471-8. 2003.... - Endotoxin, atopy and asthmaAmrutha D Holla
Division of Pediatric Allergy and Immunology, National Jewish Medical and Research Center, Denver, Colorado 80206, USA
Curr Opin Allergy Clin Immunol 2:141-5. 2002..Indeed, infections have been associated with less atopy and asthma. Recent investigations have suggested that naturally-occurring non-infectious exposure to microbial components such as endotoxin might mitigate atopy and asthma as well... - Endotoxin exposure in allergy and asthma: reconciling a paradoxAndrew H Liu
Division of Pediatric Allergy and Immunology, National Jewish Medical and Research Center, and the Department of Pediatrics, University of Colorado Health Sciences Center, Denver 80206, USA
J Allergy Clin Immunol 109:379-92. 2002.... - Biomarkers and childhood asthma: improving control today and tomorrowAndrew H Liu
Department of Pediatric Allergy and Immunology, University of Colorado Health Sciences Center, Denver, CO, USA
Allergy Asthma Proc 26:249-54. 2005..This article reconsiders the use of current and emerging measures of lung dysfunction, inflammation, and atopy in assessing tight control and long-term risk. Concluding emphasis will be placed on what can be implemented today... - Advances in childhood asthma: hygiene hypothesis, natural history, and managementAndrew H Liu
National Jewish Medical and Research Center, and the University of Colorado Health Sciences Center, Denver, CO, USA
J Allergy Clin Immunol 111:S785-92. 2003.... - Early intervention for asthma prevention in childrenAndrew H Liu
Division of Pediatric Allergy and Immunology, National Jewish Medical and Research Center, University of Colorado Health Sciences Center, 1400 Jackson St, Denver, CO 80206, USA
Allergy Asthma Proc 23:289-93. 2002.... - Corticosteroid-resistant asthma is associated with classical antimicrobial activation of airway macrophagesElena Goleva
Department of Pediatrics, National Jewish Health, Denver, CO 80206, USA
J Allergy Clin Immunol 122:550-9.e3. 2008..The cause of corticosteroid-resistant (CR) asthma is unknown... - Leukotriene-E4 in human urine: Comparison of on-line purification and liquid chromatography-tandem mass spectrometry to affinity purification followed by enzyme immunoassayMichael Armstrong
National Jewish Health, Department of Immunology, 1400 Jackson Street K924, Denver, CO 80206, USA
J Chromatogr B Analyt Technol Biomed Life Sci 877:3169-74. 2009..Results from sample integrity experiments and preliminary values of urinary LTE(4) from healthy adults and children are reported... - The inner-city asthma epidemic reaches far and wideJoseph D Spahn
Ann Allergy Asthma Immunol 96:759-61. 2006 - Asthma end points and outcomes: what have we learned?Don Bukstein
Allergy and Asthma Research, Dean Medical Center, Department of Pediatrics and Family Practice, University of Wisconsin Medical School, Madison, Wisconsin, USA
J Allergy Clin Immunol 118:S1-15. 2006..The fraction of exhaled nitric oxide as a measure of inflammation is suggested as offering the best combination of disease evaluation and practical implementation for improved asthma outcomes... - Long-term inhaled corticosteroids in preschool children at high risk for asthmaTheresa W Guilbert
Division of Pediatric Pulmonary Medicine, Arizona Respiratory Center, University of Arizona, Tucson, AZ 85724, USA
N Engl J Med 354:1985-97. 2006..It is unknown whether inhaled corticosteroids can modify the subsequent development of asthma in preschool children at high risk for asthma... - Renaissance of the hygiene hypothesisAndrew H Liu
J Allergy Clin Immunol 117:1063-6. 2006
Research Grants
- ENDOTOXIN AND ASTHMA PREVENTION IN YOUNG CHILDRENAndrew Liu; Fiscal Year: 2005..A specific Research Career Development Plan has been designed by the Candidate that includes the research described above in order to accomplish the goals of this Award. ..