Research Topics
| Shmuel LissekSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Sensation seeking and the aversive motivational systemShmuel Lissek
National Institute of Mental Health, Mood and Anxiety Disorders Program, Bethesda, MD 20892 2670, USA
Emotion 5:396-407. 2005..Findings implicate enhanced apprehensive anticipation among those low on SS as a potential deterrent for their participation in intense and threatening stimulus events...
Sensation seeking and startle modulation by physically threatening imagesShmuel Lissek
National Institute of Mental Health, Mood and Anxiety Disorders Program, 15K North Drive, Bldg 15k, MSC 2670, Bethesda, MD 20892 2670, USA
Biol Psychol 63:179-97. 2003..No attenuation in startle magnitude was elicited by positive images among low or high sensation seekers suggesting that the positive images employed in the current study were not arousing enough to activate the appetitive arousal system...
The strong situation: a potential impediment to studying the psychobiology and pharmacology of anxiety disordersShmuel Lissek
DHHS, NIH, National Institute of Mental Health, Mood and Anxiety Disorders Program, Bethesda, MD 20892 2670, USA
Biol Psychol 72:265-70. 2006....
Emotion regulation and potentiated startle across affective picture and threat-of-shock paradigmsShmuel Lissek
Mood and Anxiety Disorders Program, National Institute of Mental Health, NIH, DHHS, 15K North Drive, Bethesda, MD 20892 2670, USA
Biol Psychol 76:124-33. 2007....
Classical fear conditioning in the anxiety disorders: a meta-analysisShmuel Lissek
Mood and Anxiety Disorders Program, National Institute of Mental Health, 15K North Drive, Bldg 15k, MSC 2670, Bethesda, MD 20892 2670, USA
Behav Res Ther 43:1391-424. 2005....
Airpuff startle probes: an efficacious and less aversive alternative to white-noiseShmuel Lissek
Mood and Anxiety Disorders Program, National Institute of Mental Health NIH, DHHS, 15K North Drive, Bldg 15k, MSC 2670, Bethesda, MD 20892 2670, USA
Biol Psychol 68:283-97. 2005..Such results support the use of low intensity airpuffs as efficacious and relatively non-aversive startle probes...
Overgeneralization of conditioned fear as a pathogenic marker of panic disorderShmuel Lissek
Mood and Anxiety Disorders Program, NIMH Intramural Research Program, Bethesda, MD, USA
Am J Psychiatry 167:47-55. 2010..The authors conducted a laboratory-based assessment of this potential correlate of panic disorder by testing the degree to which panic patients and healthy subjects manifest generalization of conditioned fear...
Elevated fear conditioning to socially relevant unconditioned stimuli in social anxiety disorderShmuel Lissek
NIMH, NIH, 15K North Dr, Rm 200, Bethesda, MD 20892 2670, USA
Am J Psychiatry 165:124-32. 2008..This study represents the first effort to assess the conditioning correlates of social anxiety disorder within an ecologically enhanced paradigm...
Impaired discriminative fear-conditioning resulting from elevated fear responding to learned safety cues among individuals with panic disorderShmuel Lissek
Mood and Anxiety Disorders Program, National Institute of Mental Health Intramural Research Program, NIH, DHHS, MD 20892 2670, USA
Behav Res Ther 47:111-8. 2009..Such results link PD to impaired discrimination learning, reflecting elevated fear responding to learned safety cues...
Increased anxiety during anticipation of unpredictable aversive stimuli in posttraumatic stress disorder but not in generalized anxiety disorderChristian Grillon
Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892 2670, USA
Biol Psychiatry 66:47-53. 2009..This study tested the hypothesis that elevated anxious reactivity, specifically for unpredictable aversive events, is a psychophysiological correlate of PTSD...
Increased anxiety during anticipation of unpredictable but not predictable aversive stimuli as a psychophysiologic marker of panic disorderChristian Grillon
NIMH MAP, 15K North Dr, Bldg 15k, Rm 113, MSC 2670, Bethesda, MD 20892 2670, USA
Am J Psychiatry 165:898-904. 2008..The authors tested the hypothesis that elevated anxious reactivity, specifically toward unpredictable aversive events, is a psychophysiological correlate of panic disorder...
Development of anxiety: the role of threat appraisal and fear learningJennifer C Britton
Mood and Anxiety Disorders Program, National Institute of Mental Health, 9000 Rockville Pike, Bethesda, MD 20892, USA
Depress Anxiety 28:5-17. 2011..This novel paradigm can be used to investigate key questions relevant to prognosis and treatment. Depression and Anxiety, 2011.© 2010 Wiley-Liss, Inc...
Anxiety overrides the blocking effects of high perceptual load on amygdala reactivity to threat-related distractorsBrian R Cornwell
National Institute of Mental Health, Bethesda, MD, USA
Neuropsychologia 49:1363-8. 2011..We conclude that anxiety elicited by looming threat promotes neurocognitive processes that broaden attention and enhance sensitivity to potential danger cues, even when perceptual systems are taxed...
The benzodiazepine alprazolam dissociates contextual fear from cued fear in humans as assessed by fear-potentiated startleChristian Grillon
Mood and Anxiety Disorder Program, National Institutes of Mental Health, Bethesda, Maryland 20892 2670, USA
Biol Psychiatry 60:760-6. 2006..The present study tested the hypothesis that alprazolam would reduce the sustained startle potentiation to contextual threats but not the startle potentiation to a threat cue...
Fear conditioning in virtual reality contexts: a new tool for the study of anxietyJohanna M Baas
Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Health, U.S. Department of Health and Human Services, Bethesda, Maryland 20892, USA
Biol Psychiatry 55:1056-60. 2004..CONCLUSIONS: These results support the future use of virtual reality to design new conditioning experiments to study both fear and anxiety...
Reduction of trace but not delay eyeblink conditioning in panic disorderChristian Grillon
NIMH Mood and Anxiety Disorders Program, 15K North Dr, MSC 2670, Bethesda, MD 20892, USA
Am J Psychiatry 164:283-9. 2007..The present study examined trace eyeblink conditioning in order to test the hypothesis that individuals with panic disorder are impaired in associative learning tasks that depend on declarative memory...
Face-emotion processing in offspring at risk for panic disorderDaniel S Pine
Section on Development and Affective Neuroscience, National Institute of Mental Health Intramural Research Program, Bethesda, MD 20817 2670, USA
J Am Acad Child Adolesc Psychiatry 44:664-72. 2005..This study tested the hypotheses that offspring of parents with PD and offspring with anxiety disorders display relatively greater sensitivity and attention allocation to fear provocation...
Generalization of conditioned fear-potentiated startle in humans: experimental validation and clinical relevanceShmuel Lissek
Mood and Anxiety Disorders Program, National Institute of Mental Health, Intramural Research Program, NIH, DHHS, 15K North Drive, Rm 200, Bethesda, MD 20892 2670, USA
Behav Res Ther 46:678-87. 2008..The current paradigm represents an updated and efficacious tool with which to study fear generalization--a central, yet understudied conditioning-correlate of pathologic anxiety...
Fear conditioning in adolescents with anxiety disorders: results from a novel experimental paradigmJennifer Y F Lau
Mood and Anxiety Disorders Program, National Institute of Mental Health National Institutes of Health, 15K North Drive, MSC 2670, Bethesda, MD 20892 2670, USA
J Am Acad Child Adolesc Psychiatry 47:94-102. 2008..Adult data suggest that anxiety disorders involve elevated fear but intact differential conditioning. We used a novel paradigm to assess fear conditioning in pediatric anxiety patients...
Neural responses to auditory stimulus deviance under threat of electric shock revealed by spatially-filtered magnetoencephalographyBrian R Cornwell
Mood and Anxiety Disorders Program, National Institute of Mental Health, 15K North Drive, MSC 2670, Bethesda, MD 20892, USA
Neuroimage 37:282-9. 2007....
Anxious responses to predictable and unpredictable aversive eventsChristian Grillon
Mood and Anxiety Disorder Program, National Institute of Mental Health, 15K North Drive, Bldg 15k, Room 113, MSC 2670, Bethesda, MD 20892 2670, USA
Behav Neurosci 118:916-24. 2004..Because predictable and unpredictable danger may induce different types of aversive responses, the proposed design can serve as a useful tool for studying the neurobiology and psychopharmacology of fear and anxiety...
Face-memory and emotion: associations with major depression in children and adolescentsDaniel S Pine
Section on Development and Affective Neuroscience, Mood and Anxiety Disorders Program, National Institute of Mental Health Intramural Research Program, Bethesda, Maryland, USA
J Child Psychol Psychiatry 45:1199-208. 2004..The study also examines the relationship between parental MDD and memory performance in offspring...
Major depression predicts an increase in long-term body weight variability in young adultsGregor Hasler
Psychiatric University Hospital, Zurich, Switzerland
Obes Res 13:1991-8. 2005..To test the hypothesis that major depression predicts an increase in long-term body weight variability (BWV)...
