Shmuel Lissek

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Elevated fear conditioning to socially relevant unconditioned stimuli in social anxiety disorder
    Shmuel Lissek
    NIMH, NIH, 15K North Dr, Rm 200, Bethesda, MD 20892 2670, USA
    Am J Psychiatry 165:124-32. 2008
  2. pmc Generalization of conditioned fear-potentiated startle in humans: experimental validation and clinical relevance
    Shmuel Lissek
    Mood and Anxiety Disorders Program, National Institute of Mental Health, Intramural Research Program, NIH, DHHS, 15K North Drive, Rm 200, Bethesda, MD 20892 2670, USA
    Behav Res Ther 46:678-87. 2008
  3. pmc Impaired discriminative fear-conditioning resulting from elevated fear responding to learned safety cues among individuals with panic disorder
    Shmuel Lissek
    Mood and Anxiety Disorders Program, National Institute of Mental Health Intramural Research Program, NIH, DHHS, MD 20892 2670, USA
    Behav Res Ther 47:111-8. 2009
  4. pmc Overgeneralization of conditioned fear as a pathogenic marker of panic disorder
    Shmuel Lissek
    Mood and Anxiety Disorders Program, NIMH Intramural Research Program, Bethesda, MD, USA
    Am J Psychiatry 167:47-55. 2010
  5. pmc Emotion regulation and potentiated startle across affective picture and threat-of-shock paradigms
    Shmuel Lissek
    Mood and Anxiety Disorders Program, National Institute of Mental Health, NIH, DHHS, 15K North Drive, Bethesda, MD 20892 2670, USA
    Biol Psychol 76:124-33. 2007
  6. ncbi request reprint Reduction of trace but not delay eyeblink conditioning in panic disorder
    Christian Grillon
    NIMH Mood and Anxiety Disorders Program, 15K North Dr, MSC 2670, Bethesda, MD 20892, USA
    Am J Psychiatry 164:283-9. 2007
  7. pmc Increased anxiety during anticipation of unpredictable but not predictable aversive stimuli as a psychophysiologic marker of panic disorder
    Christian Grillon
    NIMH MAP, 15K North Dr, Bldg 15k, Rm 113, MSC 2670, Bethesda, MD 20892 2670, USA
    Am J Psychiatry 165:898-904. 2008
  8. pmc Development of anxiety: the role of threat appraisal and fear learning
    Jennifer C Britton
    Mood and Anxiety Disorders Program, National Institute of Mental Health, 9000 Rockville Pike, Bethesda, MD 20892, USA
    Depress Anxiety 28:5-17. 2011
  9. pmc Anxiety overrides the blocking effects of high perceptual load on amygdala reactivity to threat-related distractors
    Brian R Cornwell
    National Institute of Mental Health, Bethesda, MD, USA
    Neuropsychologia 49:1363-8. 2011
  10. pmc Increased anxiety during anticipation of unpredictable aversive stimuli in posttraumatic stress disorder but not in generalized anxiety disorder
    Christian Grillon
    Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892 2670, USA
    Biol Psychiatry 66:47-53. 2009

Detail Information

Publications24

  1. pmc Elevated fear conditioning to socially relevant unconditioned stimuli in social anxiety disorder
    Shmuel Lissek
    NIMH, NIH, 15K North Dr, Rm 200, Bethesda, MD 20892 2670, USA
    Am J Psychiatry 165:124-32. 2008
    ..This study represents the first effort to assess the conditioning correlates of social anxiety disorder within an ecologically enhanced paradigm...
  2. pmc Generalization of conditioned fear-potentiated startle in humans: experimental validation and clinical relevance
    Shmuel Lissek
    Mood and Anxiety Disorders Program, National Institute of Mental Health, Intramural Research Program, NIH, DHHS, 15K North Drive, Rm 200, Bethesda, MD 20892 2670, USA
    Behav Res Ther 46:678-87. 2008
    ..The current paradigm represents an updated and efficacious tool with which to study fear generalization--a central, yet understudied conditioning-correlate of pathologic anxiety...
  3. pmc Impaired discriminative fear-conditioning resulting from elevated fear responding to learned safety cues among individuals with panic disorder
    Shmuel Lissek
    Mood and Anxiety Disorders Program, National Institute of Mental Health Intramural Research Program, NIH, DHHS, MD 20892 2670, USA
    Behav Res Ther 47:111-8. 2009
    ..Such results link PD to impaired discrimination learning, reflecting elevated fear responding to learned safety cues...
  4. pmc Overgeneralization of conditioned fear as a pathogenic marker of panic disorder
    Shmuel Lissek
    Mood and Anxiety Disorders Program, NIMH Intramural Research Program, Bethesda, MD, USA
    Am J Psychiatry 167:47-55. 2010
    ..The authors conducted a laboratory-based assessment of this potential correlate of panic disorder by testing the degree to which panic patients and healthy subjects manifest generalization of conditioned fear...
  5. pmc Emotion regulation and potentiated startle across affective picture and threat-of-shock paradigms
    Shmuel Lissek
    Mood and Anxiety Disorders Program, National Institute of Mental Health, NIH, DHHS, 15K North Drive, Bethesda, MD 20892 2670, USA
    Biol Psychol 76:124-33. 2007
    ....
  6. ncbi request reprint Reduction of trace but not delay eyeblink conditioning in panic disorder
    Christian Grillon
    NIMH Mood and Anxiety Disorders Program, 15K North Dr, MSC 2670, Bethesda, MD 20892, USA
    Am J Psychiatry 164:283-9. 2007
    ..The present study examined trace eyeblink conditioning in order to test the hypothesis that individuals with panic disorder are impaired in associative learning tasks that depend on declarative memory...
  7. pmc Increased anxiety during anticipation of unpredictable but not predictable aversive stimuli as a psychophysiologic marker of panic disorder
    Christian Grillon
    NIMH MAP, 15K North Dr, Bldg 15k, Rm 113, MSC 2670, Bethesda, MD 20892 2670, USA
    Am J Psychiatry 165:898-904. 2008
    ..The authors tested the hypothesis that elevated anxious reactivity, specifically toward unpredictable aversive events, is a psychophysiological correlate of panic disorder...
  8. pmc Development of anxiety: the role of threat appraisal and fear learning
    Jennifer C Britton
    Mood and Anxiety Disorders Program, National Institute of Mental Health, 9000 Rockville Pike, Bethesda, MD 20892, USA
    Depress Anxiety 28:5-17. 2011
    ..This novel paradigm can be used to investigate key questions relevant to prognosis and treatment. Depression and Anxiety, 2011.© 2010 Wiley-Liss, Inc...
  9. pmc Anxiety overrides the blocking effects of high perceptual load on amygdala reactivity to threat-related distractors
    Brian R Cornwell
    National Institute of Mental Health, Bethesda, MD, USA
    Neuropsychologia 49:1363-8. 2011
    ..We conclude that anxiety elicited by looming threat promotes neurocognitive processes that broaden attention and enhance sensitivity to potential danger cues, even when perceptual systems are taxed...
  10. pmc Increased anxiety during anticipation of unpredictable aversive stimuli in posttraumatic stress disorder but not in generalized anxiety disorder
    Christian Grillon
    Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892 2670, USA
    Biol Psychiatry 66:47-53. 2009
    ..This study tested the hypothesis that elevated anxious reactivity, specifically for unpredictable aversive events, is a psychophysiological correlate of PTSD...
  11. ncbi request reprint The benzodiazepine alprazolam dissociates contextual fear from cued fear in humans as assessed by fear-potentiated startle
    Christian Grillon
    Mood and Anxiety Disorder Program, National Institutes of Mental Health, Bethesda, Maryland 20892 2670, USA
    Biol Psychiatry 60:760-6. 2006
    ..The present study tested the hypothesis that alprazolam would reduce the sustained startle potentiation to contextual threats but not the startle potentiation to a threat cue...
  12. pmc Fear conditioning in adolescents with anxiety disorders: results from a novel experimental paradigm
    Jennifer Y F Lau
    Mood and Anxiety Disorders Program, National Institute of Mental Health National Institutes of Health, 15K North Drive, MSC 2670, Bethesda, MD 20892 2670, USA
    J Am Acad Child Adolesc Psychiatry 47:94-102. 2008
    ..Adult data suggest that anxiety disorders involve elevated fear but intact differential conditioning. We used a novel paradigm to assess fear conditioning in pediatric anxiety patients...
  13. ncbi request reprint Sensation seeking and the aversive motivational system
    Shmuel Lissek
    National Institute of Mental Health, Mood and Anxiety Disorders Program, Bethesda, MD 20892 2670, USA
    Emotion 5:396-407. 2005
    ..Findings implicate enhanced apprehensive anticipation among those low on SS as a potential deterrent for their participation in intense and threatening stimulus events...
  14. ncbi request reprint Face-emotion processing in offspring at risk for panic disorder
    Daniel S Pine
    Section on Development and Affective Neuroscience, National Institute of Mental Health Intramural Research Program, Bethesda, MD 20817 2670, USA
    J Am Acad Child Adolesc Psychiatry 44:664-72. 2005
    ..This study tested the hypotheses that offspring of parents with PD and offspring with anxiety disorders display relatively greater sensitivity and attention allocation to fear provocation...
  15. ncbi request reprint Classical fear conditioning in the anxiety disorders: a meta-analysis
    Shmuel Lissek
    Mood and Anxiety Disorders Program, National Institute of Mental Health, 15K North Drive, Bldg 15k, MSC 2670, Bethesda, MD 20892 2670, USA
    Behav Res Ther 43:1391-424. 2005
    ....
  16. pmc Neural responses to auditory stimulus deviance under threat of electric shock revealed by spatially-filtered magnetoencephalography
    Brian R Cornwell
    Mood and Anxiety Disorders Program, National Institute of Mental Health, 15K North Drive, MSC 2670, Bethesda, MD 20892, USA
    Neuroimage 37:282-9. 2007
    ....
  17. ncbi request reprint Airpuff startle probes: an efficacious and less aversive alternative to white-noise
    Shmuel Lissek
    Mood and Anxiety Disorders Program, National Institute of Mental Health NIH, DHHS, 15K North Drive, Bldg 15k, MSC 2670, Bethesda, MD 20892 2670, USA
    Biol Psychol 68:283-97. 2005
    ..Such results support the use of low intensity airpuffs as efficacious and relatively non-aversive startle probes...
  18. ncbi request reprint Fear conditioning in virtual reality contexts: a new tool for the study of anxiety
    Johanna M Baas
    Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Health, U S Department of Health and Human Services, Bethesda, Maryland 20892, USA
    Biol Psychiatry 55:1056-60. 2004
    ..A virtual environment might prove to be the ideal tool for innovative experimental paradigms to study explicitly cued fear and contextual anxiety in humans...
  19. pmc Generalized anxiety disorder is associated with overgeneralization of classically conditioned fear
    Shmuel Lissek
    Intramural Research Program, National Institute of Mental Health, Bethesda, Maryland Department of Psychology, University of Minnesota, Minneapolis, Minnesota Electronic address
    Biol Psychiatry 75:909-15. 2014
    ..The current study fills this gap by behaviorally and psychophysiologically assessing levels of conditioned fear generalization across adults with and without GAD...
  20. ncbi request reprint The strong situation: a potential impediment to studying the psychobiology and pharmacology of anxiety disorders
    Shmuel Lissek
    DHHS, NIH, National Institute of Mental Health, Mood and Anxiety Disorders Program, Bethesda, MD 20892 2670, USA
    Biol Psychol 72:265-70. 2006
    ....
  21. ncbi request reprint Anxious responses to predictable and unpredictable aversive events
    Christian Grillon
    Mood and Anxiety Disorder Program, National Institute of Mental Health, 15K North Drive, Bldg 15k, Room 113, MSC 2670, Bethesda, MD 20892 2670, USA
    Behav Neurosci 118:916-24. 2004
    ..Because predictable and unpredictable danger may induce different types of aversive responses, the proposed design can serve as a useful tool for studying the neurobiology and psychopharmacology of fear and anxiety...
  22. ncbi request reprint Sensation seeking and startle modulation by physically threatening images
    Shmuel Lissek
    National Institute of Mental Health, Mood and Anxiety Disorders Program, 15K North Drive, Bldg 15k, MSC 2670, Bethesda, MD 20892 2670, USA
    Biol Psychol 63:179-97. 2003
    ..No attenuation in startle magnitude was elicited by positive images among low or high sensation seekers suggesting that the positive images employed in the current study were not arousing enough to activate the appetitive arousal system...
  23. ncbi request reprint Face-memory and emotion: associations with major depression in children and adolescents
    Daniel S Pine
    Section on Development and Affective Neuroscience, Mood and Anxiety Disorders Program, National Institute of Mental Health Intramural Research Program, Bethesda, Maryland, USA
    J Child Psychol Psychiatry 45:1199-208. 2004
    ..The study also examines the relationship between parental MDD and memory performance in offspring...
  24. ncbi request reprint Major depression predicts an increase in long-term body weight variability in young adults
    Gregor Hasler
    Psychiatric University Hospital, Zurich, Switzerland
    Obes Res 13:1991-8. 2005
    ..To test the hypothesis that major depression predicts an increase in long-term body weight variability (BWV)...