Barbara K Lipska

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Effects of reversible inactivation of the neonatal ventral hippocampus on behavior in the adult rat
    Barbara K Lipska
    Clinical Brain Disorders Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892 1385, USA
    J Neurosci 22:2835-42. 2002
  2. ncbi request reprint RGS4 mRNA expression in postmortem human cortex is associated with COMT Val158Met genotype and COMT enzyme activity
    Barbara K Lipska
    Clinical Brain Disorders Branch, Genes, Cognition and Psychosis Program, National Institute for Mental Health, NIH, DHHS, Bethesda, MD 20892 1385, USA
    Hum Mol Genet 15:2804-12. 2006
  3. ncbi request reprint Critical factors in gene expression in postmortem human brain: Focus on studies in schizophrenia
    Barbara K Lipska
    Clinical Brain Disorders Branch, Division of Intramural Research Programs, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892 1385, USA
    Biol Psychiatry 60:650-8. 2006
  4. pmc Functional genomics in postmortem human brain: abnormalities in a DISC1 molecular pathway in schizophrenia
    Barbara K Lipska
    Clinical Brain Disorders Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA
    Dialogues Clin Neurosci 8:353-7. 2006
  5. pmc Using animal models to test a neurodevelopmental hypothesis of schizophrenia
    Barbara K Lipska
    Clinical Brain Disorders Branch, Intramural Research Program, National Institute of Mental Health, Bethesda, MD 20892 1385, USA
    J Psychiatry Neurosci 29:282-6. 2004
  6. ncbi request reprint The neonatal ventral hippocampal lesion model of schizophrenia: effects on dopamine and GABA mRNA markers in the rat midbrain
    Barbara K Lipska
    Clinical Brain Disorders Branch, National Institute of Mental Health, Bldg 10, Rm 4 N306, Bethesda, MD 20892 1385, USA
    Eur J Neurosci 18:3097-104. 2003
  7. ncbi request reprint Gene expression in dopamine and GABA systems in an animal model of schizophrenia: effects of antipsychotic drugs
    Barbara K Lipska
    Clinical Brain Disorders Branch, Intramural Research Program, National Institute of Mental Health, NIH, Bldg 10, Rm 4N306, Bethesda, MD 20892 1385, USA
    Eur J Neurosci 18:391-402. 2003
  8. ncbi request reprint Behavioral effects of neonatal and adult excitotoxic lesions of the mediodorsal thalamus in the adult rat
    Barbara K Lipska
    Intramural Research Program, Clinical Brain Disorders Branch, National Institute of Mental Health, National Institutes of Health, 10 Center Drive, Bldg 10, Rm 4N306, Bethesda, MD 20892 1385, USA
    Behav Brain Res 141:105-11. 2003
  9. ncbi request reprint Neonatal damage of the ventral hippocampus impairs working memory in the rat
    Barbara K Lipska
    Clinical Brain Disorders Branch, NIMH IRP, Building 10, Room 4N306, Bethesda, MD 20892 1385, USA
    Neuropsychopharmacology 27:47-54. 2002
  10. ncbi request reprint Expression of DISC1 binding partners is reduced in schizophrenia and associated with DISC1 SNPs
    Barbara K Lipska
    Clinical Brain Disorders Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, 10 Center Drive, Bethesda, MD 20892, USA
    Hum Mol Genet 15:1245-58. 2006

Collaborators

Detail Information

Publications50

  1. ncbi request reprint Effects of reversible inactivation of the neonatal ventral hippocampus on behavior in the adult rat
    Barbara K Lipska
    Clinical Brain Disorders Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892 1385, USA
    J Neurosci 22:2835-42. 2002
    ..These results represent a potential new model of aspects of schizophrenia without involving a gross anatomic lesion...
  2. ncbi request reprint RGS4 mRNA expression in postmortem human cortex is associated with COMT Val158Met genotype and COMT enzyme activity
    Barbara K Lipska
    Clinical Brain Disorders Branch, Genes, Cognition and Psychosis Program, National Institute for Mental Health, NIH, DHHS, Bethesda, MD 20892 1385, USA
    Hum Mol Genet 15:2804-12. 2006
    ..These data suggest that RGS4 mRNA expression is associated with cortical dopamine signaling and illustrate the importance of genetic and/or environmental background in gene expression studies in schizophrenia...
  3. ncbi request reprint Critical factors in gene expression in postmortem human brain: Focus on studies in schizophrenia
    Barbara K Lipska
    Clinical Brain Disorders Branch, Division of Intramural Research Programs, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892 1385, USA
    Biol Psychiatry 60:650-8. 2006
    ..They are, however, confounded by pre- and postmortem factors. The purpose of this study was to identify sources of variation that will enable a better design of gene expression studies and higher reliability of gene expression data...
  4. pmc Functional genomics in postmortem human brain: abnormalities in a DISC1 molecular pathway in schizophrenia
    Barbara K Lipska
    Clinical Brain Disorders Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA
    Dialogues Clin Neurosci 8:353-7. 2006
    ..These data suggest involvement of genetically linked abnormalities in the DISC1 molecular pathway in the pathophysiology of schizophrenia...
  5. pmc Using animal models to test a neurodevelopmental hypothesis of schizophrenia
    Barbara K Lipska
    Clinical Brain Disorders Branch, Intramural Research Program, National Institute of Mental Health, Bethesda, MD 20892 1385, USA
    J Psychiatry Neurosci 29:282-6. 2004
    ..The neonatal hippocampal disconnection model represents a potential new model of schizophrenia without a gross anatomical lesion...
  6. ncbi request reprint The neonatal ventral hippocampal lesion model of schizophrenia: effects on dopamine and GABA mRNA markers in the rat midbrain
    Barbara K Lipska
    Clinical Brain Disorders Branch, National Institute of Mental Health, Bldg 10, Rm 4 N306, Bethesda, MD 20892 1385, USA
    Eur J Neurosci 18:3097-104. 2003
    ....
  7. ncbi request reprint Gene expression in dopamine and GABA systems in an animal model of schizophrenia: effects of antipsychotic drugs
    Barbara K Lipska
    Clinical Brain Disorders Branch, Intramural Research Program, National Institute of Mental Health, NIH, Bldg 10, Rm 4N306, Bethesda, MD 20892 1385, USA
    Eur J Neurosci 18:391-402. 2003
    ....
  8. ncbi request reprint Behavioral effects of neonatal and adult excitotoxic lesions of the mediodorsal thalamus in the adult rat
    Barbara K Lipska
    Intramural Research Program, Clinical Brain Disorders Branch, National Institute of Mental Health, National Institutes of Health, 10 Center Drive, Bldg 10, Rm 4N306, Bethesda, MD 20892 1385, USA
    Behav Brain Res 141:105-11. 2003
    ..These results indicate that neonatal or adult excitotoxic lesions of MDT do not produce behavioral changes analogous to those seen after neonatal VH lesions and do not appear to reproduce animal model-like features of schizophrenia...
  9. ncbi request reprint Neonatal damage of the ventral hippocampus impairs working memory in the rat
    Barbara K Lipska
    Clinical Brain Disorders Branch, NIMH IRP, Building 10, Room 4N306, Bethesda, MD 20892 1385, USA
    Neuropsychopharmacology 27:47-54. 2002
    ....
  10. ncbi request reprint Expression of DISC1 binding partners is reduced in schizophrenia and associated with DISC1 SNPs
    Barbara K Lipska
    Clinical Brain Disorders Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, 10 Center Drive, Bethesda, MD 20892, USA
    Hum Mol Genet 15:1245-58. 2006
    ..Although, many other DISC1 binding partners still need to be investigated, these data implicate genetically linked abnormalities in the DISC1 molecular pathway in the pathophysiology of schizophrenia...
  11. pmc No effect of a common allelic variant in the reelin gene on intermediate phenotype measures of brain structure, brain function, and gene expression
    Heike Tost
    Clinical Brain Disorders Branch, Genes, Cognition and Psychosis Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892 1379, USA
    Biol Psychiatry 68:105-7. 2010
    ..In the largest neuroimaging intermediate phenotype study reported so far, we evaluated the effect of rs7341475 on an extended array of different neuroscientific measures...
  12. pmc Transcript-specific associations of SLC12A5 (KCC2) in human prefrontal cortex with development, schizophrenia, and affective disorders
    Ran Tao
    Clinical Brain Disorders Branch, Genes, Cognition and Psychosis Program, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892 1385, USA
    J Neurosci 32:5216-22. 2012
    ..Alternate transcripts from KCC2 may participate in the abnormal GABA signaling in the DLPFC associated with schizophrenia...
  13. ncbi request reprint Age-related changes in the expression of schizophrenia susceptibility genes in the human prefrontal cortex
    Carlo Colantuoni
    Clinical Brain Disorders Branch, Genes Cognition and Psychosis Program, IRP, NIMH, NIH, Bethesda, MD 20892, USA
    Brain Struct Funct 213:255-71. 2008
    ..All microarray data are available at NCBI's Gene Expression Omnibus: GEO Series accession number GSE11546 (http://www.ncbi.nlm.nih.gov/geo) [corrected]..
  14. ncbi request reprint Alpha7 nicotinic acetylcholine receptor mRNA expression and binding in postmortem human brain are associated with genetic variation in neuregulin 1
    Shiny V Mathew
    Intramural Research Program, National Institute of Mental Health, NIH, Bethesda, MD 20892 1385, USA
    Hum Mol Genet 16:2921-32. 2007
    ..Together, these results suggest that the molecular mechanism of the association between NRG1 risk alleles and schizophrenia may include down-regulation of nAChR alpha7 expression...
  15. pmc Expression of GABA signaling molecules KCC2, NKCC1, and GAD1 in cortical development and schizophrenia
    Thomas M Hyde
    Section on Neuropathology, Clinical Brain Disorders Branch, Genes, Cognition and Psychosis Program, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Neurosci 31:11088-95. 2011
    ..These findings suggest that abnormalities in GABA signaling critical to brain development contribute to genetic risk for schizophrenia...
  16. doi request reprint Evidence of sex-modulated association of ZNF804A with schizophrenia
    Fengyu Zhang
    Genes, Cognition and Psychosis Program and Clinical, Brain Disorders Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
    Biol Psychiatry 69:914-7. 2011
    ..A recent candidate gene study, which replicated the positive association with rs1344706, identified another positive SNP (rs7597593) in ZNF804A associated with schizophrenia...
  17. pmc Genetic variation in CACNA1C affects brain circuitries related to mental illness
    Kristin L Bigos
    Genes, Cognition, and Psychosis Program, Division of Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Arch Gen Psychiatry 67:939-45. 2010
    ..The CACNA1C gene (alpha-1C subunit of the L-type voltage-gated calcium channel) has been identified as a risk gene for bipolar disorder and schizophrenia, but the mechanism of association has not been explored...
  18. pmc Characteristics of the cation cotransporter NKCC1 in human brain: alternate transcripts, expression in development, and potential relationships to brain function and schizophrenia
    Yukitaka Morita
    Clinical Brain Disorders Branch, Genes, Cognition, and Psychosis Program, Division of Intramural Research Programs, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, Department of Psychiatry, Hiroshima City Hospital, Hiroshima City, Hiroshima Prefecture, 730 8518, Japan, Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, Maryland 21205, Neurodevelopmental and Neuropsychiatric Genetics Laboratory, Departments of Psychiatry and Cell and Developmental Biology, University of Colorado School of Medicine, Aurora, Colorado 80045, and Departments of Psychiatry, Neurology, Neuroscience and the McKusick Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205
    J Neurosci 34:4929-40. 2014
    ....
  19. pmc DISC1 splice variants are upregulated in schizophrenia and associated with risk polymorphisms
    Kenji Nakata
    Clinical Brain Disorders Branch, Division of Intramural Research Programs, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892 1385, USA
    Proc Natl Acad Sci U S A 106:15873-8. 2009
    ..Our results implicate a molecular mechanism of genetic risk associated with DISC1 involving specific alterations in gene processing...
  20. ncbi request reprint A conserved mRNA expression profile of SREB2 (GPR85) in adult human, monkey, and rat forebrain
    Mitsuyuki Matsumoto
    Clinical Brain Disorders Branch, NIMH, NIH, Bethesda, MD 20892, USA
    Brain Res Mol Brain Res 138:58-69. 2005
    ..Together, these data suggest a possible link between SREB family and neural plasticity, which may explain its extremely high conservation throughout vertebrate evolution...
  21. pmc Genetic variation in FGF20 modulates hippocampal biology
    Herve Lemaitre
    Clinical Brain Disorder Branch, Genes, Cognition, and Psychosis Program, National Institutes of Health National Institute of Mental Health, Bethesda, Maryland 20892, USA
    J Neurosci 30:5992-7. 2010
    ..These associations, from mRNA expression to brain morphology to cognition and an interaction with aging, confirm a role of FGF20 in human brain structure and function during development and aging...
  22. pmc Increased lactate levels and reduced pH in postmortem brains of schizophrenics: medication confounds
    Nader D Halim
    Graduate Program in Molecular and Cell Biology, Bethesda, MD 20814, USA
    J Neurosci Methods 169:208-13. 2008
    ....
  23. pmc Expression of oligodendrocyte-associated genes in dorsolateral prefrontal cortex of patients with schizophrenia
    Shruti N Mitkus
    Clinical Brain Disorders Branch, Section on Neuropathology, DIRP NIMH NIH, Bethesda, MD, 20892 1385, USA
    Schizophr Res 98:129-38. 2008
    ..These data illustrate the importance of genetic background in gene expression studies in schizophrenia...
  24. pmc DNA methylation signatures in development and aging of the human prefrontal cortex
    Shusuke Numata
    Clinical Brain Disorders Branch, Genes, Cognition and Psychosis Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Am J Hum Genet 90:260-72. 2012
    ..Additional discovery is made possible with a stand-alone application, BrainCloudMethyl...
  25. pmc Common genetic variation in Neuregulin 3 (NRG3) influences risk for schizophrenia and impacts NRG3 expression in human brain
    Wee Tin Kao
    Clinical Brain Disorders Branch, Genes, Cognition and Psychosis Program, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892 1385, USA
    Proc Natl Acad Sci U S A 107:15619-24. 2010
    ..Our observations strengthen the evidence that NRG3 is a schizophrenia susceptibility gene, provide quantitative insight into NRG3 transcription traits in the human brain, and reveal a probable mechanistic basis for disease association...
  26. ncbi request reprint Effects of chronic haloperidol and clozapine treatment on neurogenesis in the adult rat hippocampus
    Nader D Halim
    Clinical Brain Disorders Branch, Intramural Research Program, National Institute of Mental Health, NIH, Bethesda, MD 20892 1385, USA
    Neuropsychopharmacology 29:1063-9. 2004
    ..These preliminary findings suggest that clozapine may influence the number of cells which divide, but antipsychotics do not promote the survival of the newly generated neurons at 3 weeks after a BrdU injection...
  27. pmc Functional analysis of genetic variation in catechol-O-methyltransferase (COMT): effects on mRNA, protein, and enzyme activity in postmortem human brain
    Jingshan Chen
    Clinical Brain Disorders Branch, Genes, Cognition, and Psychosis Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Am J Hum Genet 75:807-21. 2004
    ....
  28. pmc Neuregulin 1-ErbB4-PI3K signaling in schizophrenia and phosphoinositide 3-kinase-p110δ inhibition as a potential therapeutic strategy
    Amanda J Law
    Clinical Brain Disorders Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 109:12165-70. 2012
    ....
  29. pmc Temporal dynamics and genetic control of transcription in the human prefrontal cortex
    Carlo Colantuoni
    Section on Neuropathology, Clinical Brain Disorders Branch, Genes, Cognition and Psychosis Program, IRP, NIMH, NIH, Bethesda, Maryland 20892, USA
    Nature 478:519-23. 2011
    ..v1.p1) and can also be interrogated via a biologist-friendly stand-alone application (http://www.libd.org/braincloud)...
  30. pmc Genetic dissection of the role of catechol-O-methyltransferase in cognition and stress reactivity in mice
    Francesco Papaleo
    Clinical Brain Disorders Branch, Genes, Cognition and Psychosis Program, National Institute of Mental Health, Bethesda, Maryland 20892, USA
    J Neurosci 28:8709-23. 2008
    ..Our data indicate a critical role for the COMT gene in an apparent evolutionary trade-off between cognitive and affective functions...
  31. doi request reprint Genetic neuropathology of schizophrenia: new approaches to an old question and new uses for postmortem human brains
    Joel E Kleinman
    Section on Neuropathology, Clinical Brain Disorders Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Biol Psychiatry 69:140-5. 2011
    ..Moreover, the data, interpreted judiciously, can strengthen the plausibility of the association itself...
  32. doi request reprint Evidence of statistical epistasis between DISC1, CIT and NDEL1 impacting risk for schizophrenia: biological validation with functional neuroimaging
    Kristin K Nicodemus
    Genes, Cognition and Psychosis Program, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Hum Genet 127:441-52. 2010
    ....
  33. pmc A primate-specific, brain isoform of KCNH2 affects cortical physiology, cognition, neuronal repolarization and risk of schizophrenia
    Stephen J Huffaker
    Clinical Brain Disorders Branch, National Institute of Mental Health, Bethesda, Maryland, USA
    Nat Med 15:509-18. 2009
    ..These results identify a previously undescribed KCNH2 channel isoform involved in cortical physiology, cognition and psychosis, providing a potential new therapeutic drug target...
  34. doi request reprint Expression of a GRM3 splice variant is increased in the dorsolateral prefrontal cortex of individuals carrying a schizophrenia risk SNP
    Leah J Sartorius
    Genes Cognition and Psychosis Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Neuropsychopharmacology 33:2626-34. 2008
    ..Our results suggest that rs2228595, or a neighboring SNP in linkage disequilibrium with it, may contribute to risk for schizophrenia by modulating GRM3 splicing...
  35. ncbi request reprint Reduced N-acetylaspartate in prefrontal cortex of adult rats with neonatal hippocampal damage
    Alessandro Bertolino
    Clinical Brain Disorders Branch, Intramural Research Programs, National Institute of Mental Health, NIH, 10 Center Drive Room 4S235 MSC 1379, Bethesda, MD 20892, USA
    Cereb Cortex 12:983-90. 2002
    ....
  36. ncbi request reprint Genetic mouse models of schizophrenia: from hypothesis-based to susceptibility gene-based models
    Jingshan Chen
    Clinical Brain Disorders Branch, Genes, Cognition and Psychosis Program, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
    Biol Psychiatry 59:1180-8. 2006
    ..This new generation of genetic mouse models could shed light on the etiology of schizophrenia and lead us to new hypotheses, novel diagnostic tools, and more effective therapy...
  37. pmc Genetic evidence implicating DARPP-32 in human frontostriatal structure, function, and cognition
    Andreas Meyer-Lindenberg
    Unit for Systems Neuroscience in Psychiatry, Neuroimaging Core Facility, and Clinical Brain Disorders Branch, Genes, Cognition, and Psychosis Program, National Institute for Mental Health NIMH, NIH, Bethesda, MD 20892, USA
    J Clin Invest 117:672-82. 2007
    ..Our convergent results identify a prefrontal-neostriatal system affected by variation in PPP1R1B and suggest that DARPP-32 plays a pivotal role in cognitive function and possibly in the pathogenesis of schizophrenia...
  38. pmc A comparison of human brain dissection by drill versus saw on nucleic acid quality
    Ross C Buerlein
    National Institutes of Mental Health, Clinical Brain Disorders Branch, Bethesda, MD 20892, USA
    J Neurosci Methods 179:68-70. 2009
    ..Therefore, these results support the use of a high-speed hand-held electric dental drill as an efficient and anatomically precise means of human brain dissection without compromising tissue quality...
  39. ncbi request reprint Mouse models of genetic effects on cognition: relevance to schizophrenia
    Francesco Papaleo
    Department of Neuroscience and Brain Technologies, The Italian Institute of Technology, Via Morego 30, 16163 Genova, Italy
    Neuropharmacology 62:1204-20. 2012
    ..We highlight the missing information and limitations of cognitive assays in genetically modified mice models relevant to schizophrenia pathology...
  40. ncbi request reprint A novel ELISA using PVDF microplates
    Nader D Halim
    Clinical Brain Disorders Branch, Intramural Research Program, National Institute of Mental Health, NIH, Bethesda, MD 20892 1385, USA
    J Neurosci Methods 143:163-8. 2005
    ..The intra- and inter-assay coefficients of variation for the measurement of actin in crude rat brain homogenate were 2.36 and 5.15%, respectively...
  41. ncbi request reprint Neonatal ventral hippocampal damage modifies serum corticosterone and dopamine release responses to acute footshock in adult Sprague-Dawley rats
    Stanislaw J Chrapusta
    Laboratory of Experimental Pharmacology, Polish Academy of Sciences Medical Research Center, Warsaw, Poland
    Synapse 47:270-7. 2003
    ..These data indicate that neonatal ventral hippocampal damage enhances and prolongs certain neural and neuroendocrine responses to acute physical stressor(s), and thus may affect adaptation and enhance detrimental effects of stress...
  42. pmc Post-pubertal disruption of medial prefrontal cortical dopamine-glutamate interactions in a developmental animal model of schizophrenia
    Kuei Yuan Tseng
    Center for Neuropharmacology and Neuroscience, Albany Medical College, Albany, New York, USA
    Biol Psychiatry 62:730-8. 2007
    ....
  43. ncbi request reprint Glycogen synthase kinase (GSK)-3beta levels and activity in a neurodevelopmental rat model of schizophrenia
    Carmit Nadri
    Stanley Research Center, Faculty of Health Sciences, Ben Gurion University of the Negev, Beersheva, Israel
    Brain Res Dev Brain Res 141:33-7. 2003
    ....
  44. ncbi request reprint Cortical gene expression in the neonatal ventral-hippocampal lesion rat model
    Albert H C Wong
    Department of Psychiatry, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
    Schizophr Res 77:261-70. 2005
    ..None of these genes has been extensively studied in schizophrenia, and further work with post-mortem tissue and genetic studies are ongoing...
  45. ncbi request reprint Neonatal ventral hippocampal lesions produce an elevation of DeltaFosB-like protein(s) in the rodent neocortex
    Kelly J Powell
    Department of Psychiatry and Pharmacology, Faculty of Medicine, Dalhousie University, Halifax, NS, Canada
    Neuropsychopharmacology 31:700-11. 2006
    ....
  46. pmc Neuregulin 1 transcripts are differentially expressed in schizophrenia and regulated by 5' SNPs associated with the disease
    Amanda J Law
    Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford OX3 7JX, United Kingdom
    Proc Natl Acad Sci U S A 103:6747-52. 2006
    ..These data implicate variation in isoform expression as a molecular mechanism for the genetic association of NRG1 with schizophrenia...
  47. ncbi request reprint Neonatal hippocampal damage alters electrophysiological properties of prefrontal cortical neurons in adult rats
    PATRICIO O'DONNELL
    Center for Neuropharmacology and Neuroscience, Albany Medical College, Albany, NY 12208, USA
    Cereb Cortex 12:975-82. 2002
    ....
  48. ncbi request reprint The anxiogenic beta-carboline FG-7142 inhibits locomotor exploration similarly in postweanling and adult rats
    George E Jaskiw
    Louis Stokes Cleveland Veterans Administration Medical Center, Cleveland, OH 44141, USA
    Neurosci Lett 346:5-8. 2003
    ..We conclude that FG-7142 exerts stress-like effects in postweanling rats and may be considered for use as a model of childhood stress...
  49. ncbi request reprint Alternative splicing of human metabotropic glutamate receptor 3
    Leah J Sartorius
    Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, UK
    J Neurochem 96:1139-48. 2006
    ....