Michail S Lionakis

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Drosophila and Galleria insect model hosts: new tools for the study of fungal virulence, pharmacology and immunology
    Michail S Lionakis
    Clinical Mycology Unit, Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA
    Virulence 2:521-7. 2011
  2. pmc Chemokine receptor Ccr1 drives neutrophil-mediated kidney immunopathology and mortality in invasive candidiasis
    Michail S Lionakis
    Clinical Mycology Unit, Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS Pathog 8:e1002865. 2012
  3. pmc Genetic deletion of chemokine receptor Ccr7 exacerbates atherogenesis in ApoE-deficient mice
    Wuzhou Wan
    Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 9000 Rockville Pike, Bldg 10, Rm11N113, Bethesda, MD 20892, USA
    Cardiovasc Res 97:580-8. 2013
  4. pmc Organ-specific innate immune responses in a mouse model of invasive candidiasis
    Michail S Lionakis
    Molecular Signaling Section, Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA
    J Innate Immun 3:180-99. 2011
  5. pmc Genetic deletion of chemokine receptor Ccr6 decreases atherogenesis in ApoE-deficient mice
    Wuzhou Wan
    Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Circ Res 109:374-81. 2011
  6. doi request reprint Drosophila melanogaster as a model organism for invasive aspergillosis
    Michail S Lionakis
    Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA
    Methods Mol Biol 845:455-68. 2012

Detail Information

Publications6

  1. pmc Drosophila and Galleria insect model hosts: new tools for the study of fungal virulence, pharmacology and immunology
    Michail S Lionakis
    Clinical Mycology Unit, Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA
    Virulence 2:521-7. 2011
    ..In this review, we discuss how the insects Drosophila melanogaster and Galleria mellonella can be employed for the study of various facets of host-fungal interactions as complementary hosts to conventional vertebrate animal models...
  2. pmc Chemokine receptor Ccr1 drives neutrophil-mediated kidney immunopathology and mortality in invasive candidiasis
    Michail S Lionakis
    Clinical Mycology Unit, Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS Pathog 8:e1002865. 2012
    ..Thus, neutrophil Ccr1 amplifies late renal immunopathology and increases mortality in invasive candidiasis by mediating excessive recruitment of neutrophils from the blood to the target organ...
  3. pmc Genetic deletion of chemokine receptor Ccr7 exacerbates atherogenesis in ApoE-deficient mice
    Wuzhou Wan
    Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 9000 Rockville Pike, Bldg 10, Rm11N113, Bethesda, MD 20892, USA
    Cardiovasc Res 97:580-8. 2013
    ..Here, we addressed this question by using the classic apolipoprotein E-deficient (ApoE(-/-)) mouse model of atherosclerosis...
  4. pmc Organ-specific innate immune responses in a mouse model of invasive candidiasis
    Michail S Lionakis
    Molecular Signaling Section, Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA
    J Innate Immun 3:180-99. 2011
    ..The results delineate immune responses to the same pathogen that are highly idiosyncratic for each organ tested. The work provides novel insights into the balance between effective host defense and immunopathology in IC...
  5. pmc Genetic deletion of chemokine receptor Ccr6 decreases atherogenesis in ApoE-deficient mice
    Wuzhou Wan
    Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Circ Res 109:374-81. 2011
    ..Recent evidence suggests that both CCR6 and its ligand CCL20 are also present in human atheroma; however, their functional roles in atherogenesis remain undefined...
  6. doi request reprint Drosophila melanogaster as a model organism for invasive aspergillosis
    Michail S Lionakis
    Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA
    Methods Mol Biol 845:455-68. 2012
    ..These methods can also be adapted to study pathogenesis and antifungal drug activity against other medically important human fungal pathogens...