S M Ling

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Knee osteoarthritis compromises early mobility function: The Women's Health and Aging Study II
    Shari M Ling
    Gerontology Research Center, National Institute on Aging, Baltimore, Maryland 21224, USA
    J Rheumatol 30:114-20. 2003
  2. pmc Electromyographic patterns suggest changes in motor unit physiology associated with early osteoarthritis of the knee
    S M Ling
    Clinical Research Branch, National Institute on Aging Intramural Research Program NIA IRP, National Institutes of Health, MD 21225, USA
    Osteoarthritis Cartilage 15:1134-40. 2007
  3. ncbi request reprint Transitions to mobility difficulty associated with lower extremity osteoarthritis in high functioning older women: longitudinal data from the Women's Health and Aging Study II
    Shari M Ling
    Clinical Research Branch, National Institute on Aging Intramural Research Program, and Center on Aging and Health, The Johns Hopkins Medical Institutions, 3001 South Hanover Street, Baltimore, MD 21225, USA
    Arthritis Rheum 55:256-63. 2006
  4. pmc Serum protein signatures detect early radiographic osteoarthritis
    S M Ling
    National Institute on Aging Intramural Research Program, National Institutes of Health NIH, Baltimore, MD 21225, United States
    Osteoarthritis Cartilage 17:43-8. 2009
  5. pmc Early detection of radiographic knee osteoarthritis using computer-aided analysis
    L Shamir
    Image Informatics and Computational Biology Unit, Laboratory of Genetics, NIA, NIH, 251 Bayview Boulevard, Baltimore, MD 21224, USA
    Osteoarthritis Cartilage 17:1307-12. 2009
  6. pmc Glucose and insulin measurements from the oral glucose tolerance test and mortality prediction
    E Jeffrey Metter
    Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, Intramural Research Program, National Institutes of Health, Baltimore, Maryland 21225, USA
    Diabetes Care 31:1026-30. 2008
  7. pmc Knee x-ray image analysis method for automated detection of osteoarthritis
    Lior Shamir
    Image Informatics and Computational Biology Unit, Laboratory of Genetics, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA
    IEEE Trans Biomed Eng 56:407-15. 2009
  8. doi request reprint Age-associated changes in motor unit physiology: observations from the Baltimore Longitudinal Study of Aging
    Shari M Ling
    Clinical Research Branch, National Institute on Aging Intramural Research Program, National Institutes of Health, Baltimore, MD, USA
    Arch Phys Med Rehabil 90:1237-40. 2009
  9. pmc Role of depressive symptoms in explaining socioeconomic status disparities in dietary quality and central adiposity among US adults: a structural equation modeling approach
    May A Beydoun
    Laboratory of Personality and Cognition, National Institute on Aging, National Institutes of Health, Intramural Research Program, Baltimore, MD 21224, USA
    Am J Clin Nutr 90:1084-95. 2009
  10. pmc Gait patterns during different walking conditions in older adults with and without knee osteoarthritis--results from the Baltimore Longitudinal Study of Aging
    Seung uk Ko
    National Institute on Aging, Clinical Research Branch, Baltimore, MD 21225, USA
    Gait Posture 33:205-10. 2011

Detail Information

Publications20

  1. ncbi request reprint Knee osteoarthritis compromises early mobility function: The Women's Health and Aging Study II
    Shari M Ling
    Gerontology Research Center, National Institute on Aging, Baltimore, Maryland 21224, USA
    J Rheumatol 30:114-20. 2003
    ..Functional limitation was assessed using validated performance measures and self-report measures of task modification and task difficulty...
  2. pmc Electromyographic patterns suggest changes in motor unit physiology associated with early osteoarthritis of the knee
    S M Ling
    Clinical Research Branch, National Institute on Aging Intramural Research Program NIA IRP, National Institutes of Health, MD 21225, USA
    Osteoarthritis Cartilage 15:1134-40. 2007
    ....
  3. ncbi request reprint Transitions to mobility difficulty associated with lower extremity osteoarthritis in high functioning older women: longitudinal data from the Women's Health and Aging Study II
    Shari M Ling
    Clinical Research Branch, National Institute on Aging Intramural Research Program, and Center on Aging and Health, The Johns Hopkins Medical Institutions, 3001 South Hanover Street, Baltimore, MD 21225, USA
    Arthritis Rheum 55:256-63. 2006
    ..To assess the impact of lower extremity osteoarthritis (OA) on transitions to mobility difficulty, and to assess the influence of pain, excess weight, and quadriceps strength on these transitions...
  4. pmc Serum protein signatures detect early radiographic osteoarthritis
    S M Ling
    National Institute on Aging Intramural Research Program, National Institutes of Health NIH, Baltimore, MD 21225, United States
    Osteoarthritis Cartilage 17:43-8. 2009
    ....
  5. pmc Early detection of radiographic knee osteoarthritis using computer-aided analysis
    L Shamir
    Image Informatics and Computational Biology Unit, Laboratory of Genetics, NIA, NIH, 251 Bayview Boulevard, Baltimore, MD 21224, USA
    Osteoarthritis Cartilage 17:1307-12. 2009
    ..To determine whether computer-based analysis can detect features predictive of osteoarthritis (OA) development in radiographically normal knees...
  6. pmc Glucose and insulin measurements from the oral glucose tolerance test and mortality prediction
    E Jeffrey Metter
    Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, Intramural Research Program, National Institutes of Health, Baltimore, Maryland 21225, USA
    Diabetes Care 31:1026-30. 2008
    ..To verify what information from oral glucose tolerance tests (OGTTs) independently predicts mortality...
  7. pmc Knee x-ray image analysis method for automated detection of osteoarthritis
    Lior Shamir
    Image Informatics and Computational Biology Unit, Laboratory of Genetics, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA
    IEEE Trans Biomed Eng 56:407-15. 2009
    ..5% and 80.4%, respectively. Doubtful OA (KL grade 1) was detected automatically with a much lower accuracy of 57%. The source code developed and used in this study is available for free download at www.openmicroscopy.org...
  8. doi request reprint Age-associated changes in motor unit physiology: observations from the Baltimore Longitudinal Study of Aging
    Shari M Ling
    Clinical Research Branch, National Institute on Aging Intramural Research Program, National Institutes of Health, Baltimore, MD, USA
    Arch Phys Med Rehabil 90:1237-40. 2009
    ..To examine motor unit characteristics (size and firing rate) associated with aging...
  9. pmc Role of depressive symptoms in explaining socioeconomic status disparities in dietary quality and central adiposity among US adults: a structural equation modeling approach
    May A Beydoun
    Laboratory of Personality and Cognition, National Institute on Aging, National Institutes of Health, Intramural Research Program, Baltimore, MD 21224, USA
    Am J Clin Nutr 90:1084-95. 2009
    ..The link between socioeconomic status (SES), depression, dietary quality, and central adiposity remains unclear...
  10. pmc Gait patterns during different walking conditions in older adults with and without knee osteoarthritis--results from the Baltimore Longitudinal Study of Aging
    Seung uk Ko
    National Institute on Aging, Clinical Research Branch, Baltimore, MD 21225, USA
    Gait Posture 33:205-10. 2011
    ..Whether these conditions represent subsequent steps in the causal pathway from knee-OA to changes in gait is still not clear...
  11. ncbi request reprint A home-based protocol of electrical muscle stimulation for quadriceps muscle strength in older adults with osteoarthritis of the knee
    Laura A Talbot
    The Johns Hopkins University, School of Nursing, Baltimore, Maryland 21205 2110, USA
    J Rheumatol 30:1571-8. 2003
    ..To determine whether home-based neuromuscular electrical stimulation (NMES) applied to the quadriceps femoris (QF) muscle increases strength, physical activity, and physical performance in older adults with knee osteoarthritis (OA)...
  12. ncbi request reprint Physical and cognitive performance and burden of anticholinergics, sedatives, and ACE inhibitors in older women
    Y J Cao
    National Institute on Aging Intramural Research Program, Baltimore, Maryland, USA
    Clin Pharmacol Ther 83:422-9. 2008
    ....
  13. ncbi request reprint Effects of knee injection on skeletal muscle metabolism and contractile force in rats
    C J Galban
    Drug Delivery and Kinetics Resource, Division of Bioengineering and Physical Science, Office of Research Services, National Institutes of Health, Bethesda, MD 20892 5766, USA
    Osteoarthritis Cartilage 15:550-8. 2007
    ..We tested the hypothesis that intrusion of the knee joint capsule alters quadriceps muscle metabolism and function independently from the damage induced to knee cartilage...
  14. pmc Arterial stiffness and hand osteoarthritis: a novel relationship?
    A S Saleh
    Division of Rheumatology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Osteoarthritis Cartilage 15:357-61. 2007
    ..We tested the hypothesis that these two aging-associated conditions are related to each other...
  15. ncbi request reprint The relationship between testosterone and molecular markers of inflammation in older men
    M Maggio
    Longitudinal Studies Section, Clinical Research Branch, CRB, National Institute on Aging, NIA, USA
    J Endocrinol Invest 28:116-9. 2005
    ..However, longitudinal and interventional studies are needed to confirm that T can be used therapeutically, based on its anti-inflammatory properties...
  16. doi request reprint Bone mineral content and prostate cancer risk: data from the Baltimore Longitudinal Study of Aging
    Stacy Loeb
    James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, and the National Institute on Ageing, National Institutes of Health Clinical Research Branch, Baltimore, MD, USA
    BJU Int 106:28-31. 2010
    ..Aetiology (inception cohort) Level of Evidence 2b...
  17. pmc Drug burden index score and functional decline in older people
    Sarah N Hilmer
    Intramural Research Program, National Institute on Aging, Baltimore and Bethesda, MD, USA
    Am J Med 122:1142-1149.e1-2. 2009
    ..Here we evaluate the association between DBI and functional outcomes in Health, Aging and Body Composition study participants over 5 years...
  18. ncbi request reprint Correlation between testosterone and the inflammatory marker soluble interleukin-6 receptor in older men
    Marcello Maggio
    Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, Intramural Research Program, National Institutes of Health, Baltimore, Maryland 21225, USA
    J Clin Endocrinol Metab 91:345-7. 2006
    ..An age-associated decline in testosterone (T) levels and an increase in proinflammatory cytokines contribute to chronic diseases in older men. Whether and how these changes are related is unclear...
  19. pmc The interplay between uric acid and antioxidants in relation to physical function in older persons
    Carmelinda Ruggiero
    Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland 21225, USA
    J Am Geriatr Soc 55:1206-15. 2007
    ..To investigate the relationship between circulating uric acid (UA) levels and plasma antioxidants and whether antioxidant levels modulate the association between UA and physical function...
  20. pmc Relationship between low levels of anabolic hormones and 6-year mortality in older men: the aging in the Chianti Area (InCHIANTI) study
    Marcello Maggio
    National Institute on Aging, National Institutes of Health, NIA Clinical Research Branch at Harbor Hospital, 3001 S Hanover Street, Baltimore, MD 21225, USA
    Arch Intern Med 167:2249-54. 2007
    ..We hypothesized that in older men a parallel age-associated decline in bioavailable testosterone, IGF-1, and DHEA-S secretion is associated with higher mortality independent of potential confounders...