Research Topics
Genomes and GenesSpecies | Unhee LimSummaryAffiliation: National Institutes of Health Country: USA Publications
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Publications
Alcohol, smoking, and body size in relation to incident Hodgkin's and non-Hodgkin's lymphoma riskUnhee Lim
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852, USA
Am J Epidemiol 166:697-708. 2007..19, 95% CI: 1.03, 1.38) were associated moderately with non-Hodgkin's lymphoma. These findings add to the evidence that lifestyle factors and relevant anthropometric characteristics play a role in lymphoma etiology...
Gene-nutrient interactions among determinants of folate and one-carbon metabolism on the risk of non-Hodgkin lymphoma: NCI-SEER case-control studyUnhee Lim
Division of Cancer Epidemiology and Genetics, National Cancer Institute NCI, National Institutes of Health NIH, Department of Health and Human Services DHHS, Rockville, MD 20852, USA
Blood 109:3050-9. 2007..13; 95% CI = 0.04-0.39), and MTRR Ex5+136T>CTT (OR = 0.67; 95% CI = 0.47-0.97) genotypes. Warranting replication, our finding of gene-nutrient interactions in one-carbon metabolism supports their etiologic involvement in lymphomagenesis...
Serum high-density lipoprotein cholesterol and risk of non-hodgkin lymphomaUnhee Lim
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, Maryland 20852, USA
Cancer Res 67:5569-74. 2007..06). Our findings implicate HDL-C as a preclinical indicator of NHL and warrant further prospective investigations for its etiologic contribution...
A prospective study of telomere length measured by monochrome multiplex quantitative PCR and risk of lung cancerMin Shen
Division of Cancer Epidemiology and Genetics, NCI, NIH, DHHS, Bethesda, MD 20892, United States
Lung Cancer 73:133-7. 2011..Telomere length plays an important role in chromosomal stability and tumorigenesis, and its measurement in peripheral white blood cell DNA may be a predictor of the development of lung cancer...
A prospective study of telomere length measured by monochrome multiplex quantitative PCR and risk of non-Hodgkin lymphomaQing Lan
Division of Cancer Epidemiology and Genetics, NCI, NIH, DHHS, Bethesda, Maryland 20892 7240, USA
Clin Cancer Res 15:7429-33. 2009..We hypothesized that telomere length in peripheral WBC DNA obtained from healthy individuals would be a predictor of future risk of developing non-Hodgkin lymphoma...
Etiologic heterogeneity among non-Hodgkin lymphoma subtypesLindsay M Morton
Division of Cancer Epidemiology and Genetics, National Cancer Institute NCI, National Institutes of Health NIH, Rockville, MD, USA
Blood 112:5150-60. 2008....
Mitochondrial DNA copy number and lung cancer risk in a prospective cohort studyH Dean Hosgood
Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, EPS 8118, MCS 7240, Bethesda, MD 20892 7240, USA
Carcinogenesis 31:847-9. 2010....
One-carbon metabolism biomarkers and risk of colon and rectal cancersStephanie J Weinstein
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Nutritional Epidemiology Branch, Suite 320, 6120 Executive Boulevard, Bethesda, MD 20892, USA
Cancer Epidemiol Biomarkers Prev 17:3233-40. 2008..Folate intake has been associated with reduced colorectal cancer risk; however, few studies have prospectively examined circulating folate or other related one-carbon biomarkers...
Prediagnostic total and high-density lipoprotein cholesterol and risk of cancerJiyoung Ahn
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA
Cancer Epidemiol Biomarkers Prev 18:2814-21. 2009..We examined the relationship between serum total and HDL cholesterol and risk of overall and site-specific cancers among 29,093 men in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study cohort...
Dietary factors of one-carbon metabolism in relation to non-Hodgkin lymphoma and multiple myeloma in a cohort of male smokersUnhee Lim
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Rockville, MD 20852, USA
Cancer Epidemiol Biomarkers Prev 15:1109-14. 2006..Our results suggest that high intake of vitamin B12 among heavy smokers may be protective against NHL but warrant further studies, including among nonsmokers...
Consumption of aspartame-containing beverages and incidence of hematopoietic and brain malignanciesUnhee Lim
Division of Cancer Control and Population Sciences, National Cancer Institute, 6130 Executive Boulevard, EPN 4005, Rockville, MD 20852-7344, USA
Cancer Epidemiol Biomarkers Prev 15:1654-9. 2006..73; 95% CI, 0.46-1.15; P for inverse linear trend = 0.05), or their subtypes in men and women. CONCLUSIONS: Our findings do not support the hypothesis that aspartame increases hematopoietic or brain cancer risk...
Circulating 25-hydroxyvitamin D and risk of non-hodgkin lymphoma: Cohort Consortium Vitamin D Pooling Project of Rarer CancersMark P Purdue
National Cancer Institute, Bethesda, Maryland, USA
Am J Epidemiol 172:58-69. 2010..Future research investigating the biologic basis for the sunlight-NHL association should consider alternative mechanisms, such as immunologic effects...
Genomic methylation of leukocyte DNA in relation to colorectal adenoma among asymptomatic womenUnhee Lim
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, Maryland, USA
Gastroenterology 134:47-55. 2008..We examined genomic methylation of leukocyte DNA in relation to colorectal adenoma (CRA) among asymptomatic women (40-79 years of age) participating in a multicenter colonoscopy screening study (CONCeRN Study, 2000-2002)...
A prospective study of mitochondrial DNA copy number and risk of non-Hodgkin lymphomaQing Lan
Division of Cancer Epidemiology and Genetics, National Cancer Institute NCI, National Institutes of Health NIH, Department of Health and Human Services DHHS, Bethesda, MD, USA
Blood 112:4247-9. 2008..0; 3.2 [0.7-15.7]; 14.1 [1.9-103.2]; P(trend) = .009). These results suggest that mtDNA copy number could be associated with the risk of NHL, particularly CLL/SLL...
Dairy products, calcium intake, and risk of prostate cancer in the prostate, lung, colorectal, and ovarian cancer screening trialJiyoung Ahn
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, 6120 Executive Boulevard, Bethesda, MD 20892, USA
Cancer Epidemiol Biomarkers Prev 16:2623-30. 2007..Furthermore, we found no relationship between calcium intake and circulating vitamin D...
Ultraviolet radiation, dietary vitamin D, and risk of non-Hodgkin lymphoma (United States)Patricia Hartge
Division of Cancer Epidemiology and Genetics, National Cancer Institue, Rockville, MD 20852, USA
Cancer Causes Control 17:1045-52. 2006....
Mendelian randomization: how it can--and cannot--help confirm causal relations between nutrition and cancerArthur Schatzkin
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA
Cancer Prev Res (Phila) 2:104-13. 2009..We conclude that Mendelian randomization is not universally applicable, but, under the right conditions, can complement evidence for causal associations from conventional epidemiologic studies...
The role of dietary factors in the epidemiology of non-Hodgkin's lymphomaAmanda J Cross
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852, USA
Leuk Lymphoma 47:2477-87. 2006....
Vegetables- and antioxidant-related nutrients, genetic susceptibility, and non-Hodgkin lymphoma riskLinda E Kelemen
Department of Health Sciences Research, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN, 55905, USA
Cancer Causes Control 19:491-503. 2008..Although most associations have not been examined previously with NHL, our results suggest the examined polymorphisms are not modifiers of the association between vegetable and zinc intakes and NHL risk...
One-carbon metabolism, colorectal carcinogenesis, chemoprevention--with cautionRegina G Ziegler
J Natl Cancer Inst 99:1214-5. 2007
Vegetables, fruit, and antioxidant-related nutrients and risk of non-Hodgkin lymphoma: a National Cancer Institute-Surveillance, Epidemiology, and End Results population-based case-control studyLinda E Kelemen
Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Am J Clin Nutr 83:1401-10. 2006..91; P for trend = 0.02). An effect modification by exercise and NHL subtype was observed with some food groups and nutrients. CONCLUSION: Higher intakes of vegetables, lutein and zeaxanthin, and zinc are associated with a lower NHL risk...
Polymorphisms in cytoplasmic serine hydroxymethyltransferase and methylenetetrahydrofolate reductase affect the risk of cardiovascular disease in menUnhee Lim
Division of Nutritional Sciences, Cornell University, Ithaca, NY, USA
J Nutr 135:1989-94. 2005..A more complete understanding of the molecular mechanism awaits identification of the functional effect of the polymorphism...
Homocysteine and blood pressure in the Third National Health and Nutrition Examination Survey, 1988-1994Unhee Lim
Division of Nutritional Sciences, Cornell University, Ithaca, NY 14853, USA
Am J Epidemiol 156:1105-13. 2002..The results support a mediating role for blood pressure in women and suggest that the full effect of homocysteine on cardiovascular risk may be underestimated when blood pressure is adjusted...
