Research Topics
| J LicinioSummaryAffiliation: National Institutes of Health Country: USA Publications
| Collaborators
|
Detail Information
Publications
Sex differences in circulating human leptin pulse amplitude: clinical implicationsJ Licinio
Clinical Neuroendocrinology Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892 1284, USA
J Clin Endocrinol Metab 83:4140-7. 1998....
The hypothalamic-pituitary-adrenal axis in anorexia nervosaJ Licinio
Clinical Neuroendocrinology Branch, National Institute of Mental Health, Bethesda, MD 20892, USA
Psychiatry Res 62:75-83. 1996..The contribution of circadian rhythm disturbances and malnutrition to observed HPA axis abnormalities in anorexia nervosa is also considered. Directions for future research are discussed...
The role of inflammatory mediators in the biology of major depression: central nervous system cytokines modulate the biological substrate of depressive symptoms, regulate stress-responsive systems, and contribute to neurotoxicity and neuroprotectionJ Licinio
Clinical Neuroendocrinology Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
Mol Psychiatry 4:317-27. 1999..We also discuss the emerging concept of peripheral and central cytokine compartments: their integration and differential regulation is a key element for the optimal functioning of the immune and nervous systems...
Synchronicity of frequently sampled, 24-h concentrations of circulating leptin, luteinizing hormone, and estradiol in healthy womenJ Licinio
Clinical Neuroendocrinology Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892 1284, USA
Proc Natl Acad Sci U S A 95:2541-6. 1998..This may explain the disruption of hypothalamic-pituitary-ovarian function that is characteristic of states of low leptin release, such as anorexia nervosa and cachexia...
Brain iNOS: current understanding and clinical implicationsJ Licinio
Clinical Neuroendocrinology Branch, National Institute of Mental Health, NIH Bldg 10 2D46, 10 Center Dr MSC 1284, Bethesda, MD 20892 1284, USA
Mol Med Today 5:225-32. 1999..Brain iNOS might be required for adequate repair following injury or damage. The effects of brain iNOS on the balance between damage and repair make this enzyme a promising therapeutic target in human disease...
LeptinP Prolo
Unit on Clinical Research, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892 1284, USA
Int J Biochem Cell Biol 30:1285-90. 1998..This suggests potential roles for leptin or its antagonists in the diagnosis, pathophysiology and treatment of several human diseases...
Inducible nitric oxide synthase gene expression in the brain during systemic inflammationM L Wong
Clinical Neuroendocrinology Branch, National Institutes of Mental Health, National Institutes of Health, Bethesda, Maryland 20892 1284, USA
Nat Med 2:581-4. 1996..Brain iNOS may be relevant to the pathophysiology, diagnosis and treatment of systemic inflammation and sepsis...
Focal cerebral ischemia induces CRH mRNA in rat cerebral cortex and amygdalaM L Wong
Clinical Neuroendocrinology Branch, NIMH, NIH, Bethesda, Maryland 20892 1284, USA
Neuroreport 6:1785-8. 1995..This rapid and profound increase in CRH mRNA levels during focal cerebral ischemia is likely to be associated with neurotoxicity, as CRH antagonism has been reported to cause a significant reduction in neuronal loss during ischemia...
Expression of corticotropin releasing hormone receptors type I and type II mRNA in suicide victims and controlsN Hiroi
Pediatric and Reproductive Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA
Mol Psychiatry 6:540-6. 2001..Strong expression of both CRH-R1 and CRH-R2 in human pituitaries suggests that particularly under stress, activation of the HPA axis can be maintained through both receptors...
Thyroid function in bulimia nervosaM Altemus
Laboratory of Clinical Science, DIRP, NIMH, Bethesda, MD 20892 1264, USA
Psychoneuroendocrinology 21:249-61. 1996..01), suggesting that food binging may stimulate thyroid activity. In sum, these results show a substantial reduction in thyroid hormone levels after 7 weeks of abstinence from binging and vomiting behaviors...
