Research Topics
| Qingdi Q LiSummaryAffiliation: National Institutes of Health Country: USA Publications
| Collaborators
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Detail Information
Publications
β-Elemene Promotes Cisplatin-induced Cell Death in Human Bladder Cancer and Other CarcinomasQ Quentin Li
National Institutes of Health, Bethesda, Maryland 20892, U S A E mail and Dr Yuhua Zhong, Beihai Institute of Endocrine and Metabolic Diseases, Beihai, Guangxi 536000, P R C
Anticancer Res 33:1421-8. 2013..Cisplatin combined with β-elemene as a chemosensitizer warrants further pre-clinical therapeutic studies and may be useful for the treatment of cisplatin-resistant bladder cancer and other types of carcinomas...
β-Elemene and taxanes synergistically induce cytotoxicity and inhibit proliferation in ovarian cancer and other tumor cellsBaobo Zou
National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
Anticancer Res 33:929-40. 2013..This promising new therapeutic combination warrants further pre-clinical exploration for the treatment of chemoresistant ovarian cancer and other types of tumors...
Sensitization of lung cancer cells to cisplatin by β-elemene is mediated through blockade of cell cycle progression: antitumor efficacies of β-elemene and its synthetic analogsQ Quentin Li
West Virginia University School of Medicine, Morgantown, WV 26506, USA
Med Oncol 30:488. 2013....
Anticancer activity of β-Elemene and its synthetic analogs in human malignant brain tumor cellsQingdi Quentin Li
National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
Anticancer Res 33:65-76. 2013..Overall, this study provides, to our knowledge, the first evidence showing that synthetic analogs of β-elemene hold promise for patients with brain tumors...
β-elemene effectively suppresses the growth and survival of both platinum-sensitive and -resistant ovarian tumor cellsRebecca X Lee
Department of Microbiology, Immunology and Cell Biology, Mary Babb Randolph Cancer Center, West Virginia University School of Medicine, Morgantown, WV, USA
Anticancer Res 32:3103-13. 2012....
beta-Elemene, a novel plant-derived antineoplastic agent, increases cisplatin chemosensitivity of lung tumor cells by triggering apoptosisQingdi Q Li
The Mary Babb Randolph Cancer Center and Department of Microbiology, Immunology and Cell Biology, Robert C Byrd Health Sciences Center, West Virginia University of Medicine, Morgantown, WV 26506, USA
Oncol Rep 22:161-70. 2009..Our data provide a rationale for developing a combination of beta-elemene and cisplatin as a regimen for the treatment of lung carcinoma and other cisplatin-resistant tumors...
In vitro combination characterization of the new anticancer plant drug beta-elemene with taxanes against human lung carcinomaJinshun Zhao
Mary Babb Randolph Cancer Center, Department of Microbiology, Immunology and Cell Biology, West Virginia University, Morgantown, WV 26506, USA
Int J Oncol 31:241-52. 2007..Finally, the beta-elemene-induced alteration of cell membrane permeability, which has potential to result in enhanced cellular uptake of taxanes, may also contribute to the synergistic interactions of the combination treatments...
Mechanisms underlying the synergistic effect of SU5416 and cisplatin on cytotoxicity in human ovarian tumor cellsXiaosong Zhong
Mary Babb Randolph Cancer Center, and Department of Microbiology, Immunology and Cell Biology, West Virginia University School of Medicine and Robert C. Byrd Health Sciences Center, Morgantown, WV 26506, USA
Int J Oncol 25:445-51. 2004..Together, these results suggest that the chemosensitizing effect of SU5416 on ovarian tumor cells may be mediated, at least in part, through inhibiting G1 checkpoint control and up-regulating the apoptotic response to cisplatin...
Molecular mechanism of antitumor activity of taxanes in lung cancer (Review)Jinshun Zhao
The Mary Babb Randolph Cancer Center, and Department of Microbiology, Immunology and Cell Biology, West Virginia University Health Sciences Center, Morgantown, 26506, USA
Int J Oncol 27:247-56. 2005....
Molecular basis of cellular response to cisplatin chemotherapy in non-small cell lung cancer (Review)Gangduo Wang
Mary Babb Randolph Cancer Center and Department of Microbiology, Immunology and Cell Biology, West Virginia University Health Sciences Center, Morgantown, WV 26506, USA
Oncol Rep 12:955-65. 2004....
Apoptosis in prostate cancer: progressive and therapeutic implications (Review)Gangduo Wang
Mary Babb Randolph Cancer Center, West Virginia University Health Sciences Center, Morgantown, WV 26506, USA
Int J Mol Med 14:23-34. 2004....
Transcription factor E2F-1 is upregulated in human gastric cancer tissues and its overexpression suppresses gastric tumor cell proliferationQiang Xiao
Department of Surgery, First Hospital of Guangxi Medical University, Nanning, Guangxi 530021, P R China
Cell Oncol 29:335-49. 2007....
Clinical value of combined detection of serum matrix metalloproteinase-9, heparanase, and cathepsin for determining ovarian cancer invasion and metastasisWei Zhang
Department of Gynecologic Oncology, Cancer Hospital, Guangxi Medical University, Nanning, Guangxi 530021, P R China
Anticancer Res 31:3423-8. 2011..This study evaluated the clinical value of the combined detection of serum cathepsin L (CL), heparanase (Hpa), and matrix metalloproteinase-9 (MMP-9) for determining the degree of ovarian cancer invasion and metastasis before surgery...
Demonstration of differential gene expression between sensitive and resistant ovarian tumor cells by fluorescence differential display-PCR analysisLi Li
Department of Gynecologic Oncology, Cancer Institute and Hospital, Guangxi Medical University Medical Center, Nanning, Guangxi 530021, P R China
Oncol Rep 13:793-9. 2005....
