Ira W Levin

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Magnesium-induced lipid bilayer microdomain reorganizations: implications for membrane fusion
    Zachary D Schultz
    Laboratory of Chemical Physics, National Institutes of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Phys Chem B 113:9932-41. 2009
  2. pmc Non-invasive monitoring of tissue oxygenation during laparoscopic donor nephrectomy
    Nicole J Crane
    Naval Medical Research Center, Combat Casualty Care, Silver Spring, MD 20910, USA
    BMC Surg 8:8. 2008
  3. pmc Lipid vesicle aggregation induced by cooling
    Frank B Howard
    Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Int J Mol Sci 11:754-61. 2010
  4. ncbi request reprint Fourier transform infrared vibrational spectroscopic imaging: integrating microscopy and molecular recognition
    Ira W Levin
    Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892 0520, USA
    Annu Rev Phys Chem 56:429-74. 2005
  5. pmc Advantages and artifacts of higher order modes in nanoparticle-enhanced backscattering Raman imaging
    Zachary D Schultz
    Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 9000 Rockville Pike, Bethesda, Maryland 20892, USA
    Anal Chem 81:9657-63. 2009
  6. ncbi request reprint Non-invasive detection of superimposed latent fingerprints and inter-ridge trace evidence by infrared spectroscopic imaging
    Rohit Bhargava
    Laboratory of Chemical Physics, NIDDK, National Institutes of Health, Bethesda, MD 20892 0520, USA
    Anal Bioanal Chem 394:2069-75. 2009
  7. pmc Pharmacodynamic assessment of histone deacetylase inhibitors: infrared vibrational spectroscopic imaging of protein acetylation
    Tsoching Chen
    Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Anal Chem 80:6390-6. 2008
  8. pmc Lipid microdomain formation: characterization by infrared spectroscopy and ultrasonic velocimetry
    Zachary D Schultz
    Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Biophys J 94:3104-14. 2008
  9. ncbi request reprint Infrared spectroscopic imaging for histopathologic recognition
    Daniel C Fernandez
    Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892 0520, USA
    Nat Biotechnol 23:469-74. 2005
  10. pmc Tip-enhanced Raman spectroscopy and imaging: an apical illumination geometry
    Zachary D Schultz
    Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Appl Spectrosc 62:1173-9. 2008

Collaborators

Detail Information

Publications18

  1. pmc Magnesium-induced lipid bilayer microdomain reorganizations: implications for membrane fusion
    Zachary D Schultz
    Laboratory of Chemical Physics, National Institutes of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Phys Chem B 113:9932-41. 2009
    ..The structural reorganizations of the lipid microdomains within the DPPS-DPPC bilayer are interpreted in the context of current concepts regarding lipid bilayer fusion...
  2. pmc Non-invasive monitoring of tissue oxygenation during laparoscopic donor nephrectomy
    Nicole J Crane
    Naval Medical Research Center, Combat Casualty Care, Silver Spring, MD 20910, USA
    BMC Surg 8:8. 2008
    ..However, there is no in vivo methodology to monitor renal parenchymal oxygenation during laparoscopic surgery...
  3. pmc Lipid vesicle aggregation induced by cooling
    Frank B Howard
    Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Int J Mol Sci 11:754-61. 2010
    ..Lowering the temperature of 1,2-dipalmitoyl-sn-glycero-3-phosphoserine (DPPS) vesicles from 20 degrees C to 5 degrees C failed to increase aggregation within 24 hours at Mg(++)/DPPS ratios that begin to initiate aggregation and fusion...
  4. ncbi request reprint Fourier transform infrared vibrational spectroscopic imaging: integrating microscopy and molecular recognition
    Ira W Levin
    Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892 0520, USA
    Annu Rev Phys Chem 56:429-74. 2005
    ....
  5. pmc Advantages and artifacts of higher order modes in nanoparticle-enhanced backscattering Raman imaging
    Zachary D Schultz
    Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 9000 Rockville Pike, Bethesda, Maryland 20892, USA
    Anal Chem 81:9657-63. 2009
    ..These effects are demonstrated using both carbon nanotube and fixed biological samples...
  6. ncbi request reprint Non-invasive detection of superimposed latent fingerprints and inter-ridge trace evidence by infrared spectroscopic imaging
    Rohit Bhargava
    Laboratory of Chemical Physics, NIDDK, National Institutes of Health, Bethesda, MD 20892 0520, USA
    Anal Bioanal Chem 394:2069-75. 2009
    ..Thus, trace evidence found at a crime scene that previously could not be directly related to an individual, now has the potential to be directly related by its presence in the individual-identifying fingerprints...
  7. pmc Pharmacodynamic assessment of histone deacetylase inhibitors: infrared vibrational spectroscopic imaging of protein acetylation
    Tsoching Chen
    Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Anal Chem 80:6390-6. 2008
    ..The data demonstrate a new approach to a sensitive assessment of global molecular modifications that is independent of antibodies, requires minimal cell processing, and is easily adapted to high-throughput screening...
  8. pmc Lipid microdomain formation: characterization by infrared spectroscopy and ultrasonic velocimetry
    Zachary D Schultz
    Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Biophys J 94:3104-14. 2008
    ..The combination of these two physical approaches offers new insight into microdomain formation and their properties in model bilayer systems...
  9. ncbi request reprint Infrared spectroscopic imaging for histopathologic recognition
    Daniel C Fernandez
    Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892 0520, USA
    Nat Biotechnol 23:469-74. 2005
    ..Finally, we differentiate benign from malignant prostatic epithelium by spectroscopic analyses...
  10. pmc Tip-enhanced Raman spectroscopy and imaging: an apical illumination geometry
    Zachary D Schultz
    Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Appl Spectrosc 62:1173-9. 2008
    ..Sufficient enhancement is obtained to permit a sub-diffraction-limited resolution Raman imaging of the surface distribution of large bundles of carbon nanotubes of various diameters...
  11. ncbi request reprint Time-resolved Fourier transform infrared spectroscopic imaging
    Rohit Bhargava
    Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892 0510, USA
    Appl Spectrosc 57:357-66. 2003
    ....
  12. ncbi request reprint Gram-Schmidt orthogonalization for rapid reconstructions of Fourier transform infrared spectroscopic imaging data
    Rohit Bhargava
    Laboratory of Chemical Physics, NIDDK, National Institutes of Health, Bethesda, Maryland 20892 0520, USA
    Appl Spectrosc 58:995-1000. 2004
    ..Illustrative data from human skin biopsies and from dynamic molecular reorganizations within liquid crystalline microdomains is employed to discuss the capabilities and limitations of this information-extraction approach...
  13. ncbi request reprint Reorganizational dynamics of multilamellar lipid bilayer assemblies using continuously scanning Fourier transform infrared spectroscopic imaging
    Scott W Huffman
    Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Chem Phys Lipids 130:167-74. 2004
    ..In contrast, the lipid vesicle gel phase displays no intermolecular or intramolecular dependence as a function of distance from the MLV center...
  14. pmc Contrast enhancement for in vivo visible reflectance imaging of tissue oxygenation
    Nicole J Crane
    National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland 20892
    Appl Spectrosc 61:797-803. 2007
    ..Adaptation of this filter approach is demonstrated for laparoscopic donor nephrectomies in which images are analyzed in terms of real-time in vivo monitoring of tissue oxygenation...
  15. ncbi request reprint Structural and molecular hair abnormalities in trichothiodystrophy
    Christine Liang
    DNA Repair Section, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892 4258, USA
    J Invest Dermatol 126:2210-6. 2006
    ..Our data indicate that the brittleness of the TTD hair is dependent upon abnormalities at several levels of organization. These changes make TTD hairs excessively prone to breakage and weathering...
  16. ncbi request reprint Effective time averaging of multiplexed measurements: a critical analysis
    Rohit Bhargava
    Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892 0510, USA
    Anal Chem 74:1429-35. 2002
    ....
  17. pmc Enhanced surgical imaging: laparoscopic vessel identification and assessment of tissue oxygenation
    Nicole J Crane
    Naval Medical Research Center, Combat and Casualty Care, Silver Spring, MD 20910, USA
    J Am Coll Surg 206:1159-66. 2008
    ....
  18. ncbi request reprint High throughput assessment of cells and tissues: Bayesian classification of spectral metrics from infrared vibrational spectroscopic imaging data
    Rohit Bhargava
    Department of Bioengineering and Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana Champaign, Urbana, IL 61801, USA
    Biochim Biophys Acta 1758:830-45. 2006
    ..An index of epithelial cell polarization, derived from a combined spectral and morphological analysis, is determined to be a potentially useful diagnostic marker...