Research Topics
Genomes and GenesSpecies | Michael F LeitzmannSummaryAffiliation: National Institutes of Health Country: USA Publications
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Publications
Dietary intake of n-3 and n-6 fatty acids and the risk of prostate cancerMichael F Leitzmann
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
Am J Clin Nutr 80:204-16. 2004..Laboratory studies have shown that n-3 fatty acids inhibit and n-6 fatty acids stimulate prostate tumor growth, but whether the dietary intake of these fatty acids affects prostate cancer risk in humans remains unclear...
Ejaculation frequency and subsequent risk of prostate cancerMichael F Leitzmann
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
JAMA 291:1578-86. 2004....
Physical activity and head and neck cancer riskMichael F Leitzmann
Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
Cancer Causes Control 19:1391-9. 2008..To investigate the relation of physical activity to head and neck cancer...
Physical activity recommendations and decreased risk of mortalityMichael F Leitzmann
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
Arch Intern Med 167:2453-60. 2007..Whether national physical activity recommendations are related to mortality benefit is incompletely understood...
Thiazide diuretics and the risk of gallbladder disease requiring surgery in womenMichael F Leitzmann
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, EPS MSC 7232, 6120 Executive Boulevard, Bethesda, MD 20892, USA
Arch Intern Med 165:567-73. 2005..Previous studies have suggested that thiazide diuretic use increases the risk of cholecystitis...
Alcohol consumption in relation to risk of cholecystectomy in womenMichael F Leitzmann
Department of Nutrition, Harvard School of Public Health, Boston, USA
Am J Clin Nutr 78:339-47. 2003..However, the magnitude of the association is uncertain, and little is known about the relation of alcohol consumption patterns and individual types of alcoholic beverages to gallstone disease risk...
Zinc supplement use and risk of prostate cancerMichael F Leitzmann
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
J Natl Cancer Inst 95:1004-7. 2003....
Is there a link between macronutrient intake and prostate cancer?Michael F Leitzmann
Nutritional Epidemiology Branch, US National Cancer Institute, Bethesda, MD 20892, USA
Nat Clin Pract Oncol 2:184-5. 2005
Fat, protein, and meat consumption and renal cell cancer risk: a pooled analysis of 13 prospective studiesJung Eun Lee
Channing Laboratory, Brigham and Women s Hospital, and Harvard Medical School, Boston, MA 02115, USA
J Natl Cancer Inst 100:1695-706. 2008....
Body mass index and risk of ovarian cancerMichael F Leitzmann
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
Cancer 115:812-22. 2009..However, to the authors' knowledge, data addressing whether the relation between BMI and ovarian cancer differs by MHT use are very sparse...
Body size and renal cell cancer incidence in a large US cohort studyKenneth F Adams
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA
Am J Epidemiol 168:268-77. 2008..Waist-to hip ratio was positively associated with RCC in women and with height at age 18 years in both men and women...
Alcohol and risk of breast cancer by histologic type and hormone receptor status in postmenopausal women: the NIH-AARP Diet and Health StudyJasmine Q Lew
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, Rockville, MD 20852, USA
Am J Epidemiol 170:308-17. 2009..13 (95% CI: 0.73, 1.77) for >20 g versus 0 g/day, and 1.21 (95% CI: 0.79, 1.84) for >20 g versus 0 g/day, respectively. Moderate consumption of alcohol was associated with breast cancer, specifically hormone receptor-positive tumors...
Adiposity, adult weight change, and postmenopausal breast cancer riskJiyoung Ahn
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, EPS, 6120 Executive Blvd, Bethesda, MD 20892, USA
Arch Intern Med 167:2091-102. 2007..Obesity is a risk factor for postmenopausal breast cancer, but the role of the timing and amount of adult weight change in breast cancer risk is unclear...
Diabetes mellitus and prostate cancer risk in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening TrialMichael F Leitzmann
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD 20892, USA
Cancer Causes Control 19:1267-76. 2008....
Prospective study of physical activity and risk of postmenopausal breast cancerMichael F Leitzmann
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
Breast Cancer Res 10:R92. 2008..To prospectively examine the relation of total, vigorous and non-vigorous physical activity to postmenopausal breast cancer risk...
The combined relations of adiposity and smoking on mortalityAnnemarie Koster
Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, MD 20892, USA
Am J Clin Nutr 88:1206-12. 2008..Smoking cessation is associated with increased body weight and a substantial increase in waist circumference. How this affects mortality risk is unknown...
Fruit and vegetable intake and esophageal cancer in a large prospective cohort studyNeal D Freedman
Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
Int J Cancer 121:2753-60. 2007..A significant inverse association between EAC and Chenopodiaceae (spinach) intake was observed. Results from our study suggest that the relation of fruit and vegetable intake and esophageal cancer risk may vary by histologic type...
Endometrial cancer and menopausal hormone therapy in the National Institutes of Health-AARP Diet and Health Study cohortJames V Lacey
Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland, USA
Cancer 109:1303-11. 2007....
Adipokine genes and prostate cancer riskSteven C Moore
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
Int J Cancer 124:869-76. 2009..05). Polymorphisms in the IL6, LEPR, TNF and ADIPOQ genes were not associated with prostate cancer. Allelic variants in the LEP gene are related to prostate cancer risk, supporting a role for leptin in prostate carcinogenesis...
Physical activity, sedentary behavior, and endometrial cancer risk in the NIH-AARP Diet and Health StudyGretchen L Gierach
Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD 20852 7234, USA
Int J Cancer 124:2139-47. 2009..02). Associations with vigorous activities, which may interact with body mass index, suggest directions for future research to clarify underlying biologic mechanisms, including those relating to hormonal alterations...
Intakes of vitamins A, C, and E and use of multiple vitamin supplements and risk of colon cancer: a pooled analysis of prospective cohort studiesYikyung Park
Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
Cancer Causes Control 21:1745-57. 2010..To evaluate the associations between intakes of vitamins A, C, and E and risk of colon cancer...
Dairy food, calcium, and risk of cancer in the NIH-AARP Diet and Health StudyYikyung Park
Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Bethesda, MD 20852, USA
Arch Intern Med 169:391-401. 2009..Dairy food and calcium intakes have been hypothesized to play roles that differ among individual cancer sites, but the evidence has been limited and inconsistent. Moreover, their effect on cancer in total is unclear...
Physical activity during adulthood and adolescence in relation to renal cell cancerSteven C Moore
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
Am J Epidemiol 168:149-57. 2008..82 (95% CI: 0.68, 1.00; p(trend) = 0.05) for activity during adolescence. The authors conclude that increased physical activity, including activity during adolescence, is associated with reduced risk of renal cell cancer...
Physical activity and postmenopausal breast cancer risk in the NIH-AARP diet and health studyTricia M Peters
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, 6120 Executive Boulevard, MSC 7232, Bethesda, MD 20892, USA
Cancer Epidemiol Biomarkers Prev 18:289-96. 2009..Although physical activity has been associated with reduced breast cancer risk, whether this association varies across breast cancer subtypes or is modified by reproductive and lifestyle factors is unclear...
Prospective study of alcohol drinking and renal cell cancer risk in a cohort of finnish male smokersSomdat Mahabir
Cancer Prevention Studies Branch, Center for Cancer Research, National Cancer Institute, 6116 Executive Boulevard, Suite 705, MSC 8314, Bethesda, MD 20892 7058, USA
Cancer Epidemiol Biomarkers Prev 14:170-5. 2005..Because most of the risk reductions were seen at the highest quartile of alcohol intake and alcohol is a risk factor for a number of cancers particularly among smokers, these data should be interpreted with caution...
Dietary fiber and whole-grain consumption in relation to colorectal cancer in the NIH-AARP Diet and Health StudyArthur Schatzkin
Division of Cancer Epidemiology, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
Am J Clin Nutr 85:1353-60. 2007..Whether the intake of dietary fiber can protect against colorectal cancer is a long-standing question of considerable public health import, but the epidemiologic evidence has been inconsistent...
Physical activity and esophageal and gastric carcinoma in a large prospective studyMichael F Leitzmann
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
Am J Prev Med 36:112-9. 2009..Few studies have investigated the relationship of physical activity to esophageal and gastric carcinoma according to histology and anatomic site...
Beyond recreational physical activity: examining occupational and household activity, transportation activity, and sedentary behavior in relation to postmenopausal breast cancer riskStephanie M George
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA
Am J Public Health 100:2288-95. 2010..We prospectively examined nonrecreational physical activity and sedentary behavior in relation to breast cancer risk among 97 039 postmenopausal women in the National Institutes of Health-AARP Diet and Health Study...
Lifetime weight history and endometrial cancer risk by type of menopausal hormone use in the NIH-AARP diet and health studyShih Chen Chang
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Suite 320, Executive Plaza South, MSC7232, Bethesda, MD 20892 7232, USA
Cancer Epidemiol Biomarkers Prev 16:723-30. 2007..We conclude that both current adiposity and adult weight gain are associated with substantial increases in the risk of endometrial cancer, with relations particularly evident among never users of menopausal hormone therapy...
Intensity and timing of physical activity in relation to postmenopausal breast cancer risk: the prospective NIH-AARP diet and health studyTricia M Peters
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, 6120 Executive Blvd, Bethesda, MD, USA
BMC Cancer 9:349. 2009..Despite strong evidence of an inverse association of physical activity with postmenopausal breast cancer risk, whether a certain intensity or time of life of physical activity is most effective for lowering breast cancer risk is not known...
Fruit and vegetable intake and head and neck cancer risk in a large United States prospective cohort studyNeal D Freedman
Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
Int J Cancer 122:2330-6. 2008..Results from this large prospective observational study are consistent with previous case-control studies and support the hypothesis that total fruit and vegetable intake is associated with reduced risk of head and neck cancer...
Nonsteroidal anti-inflammatory drugs and breast cancer risk in the National Institutes of Health-AARP Diet and Health StudyGretchen L Gierach
Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Blvd, Suite 550, Rockville, MD 20852 7234, USA
Breast Cancer Res 10:R38. 2008..Epidemiologic evidence for a protective role of NSAIDs in breast cancer, however, is equivocal...
Added sugar and sugar-sweetened foods and beverages and the risk of pancreatic cancer in the National Institutes of Health-AARP Diet and Health StudyYing Bao
Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
Am J Clin Nutr 88:431-40. 2008..Although it has been hypothesized that hyperglycemia, hyperinsulinemia, and insulin resistance are involved in the development of pancreatic cancer, results from epidemiologic studies of added sugar intake are inconclusive...
Body mass and colorectal cancer risk in the NIH-AARP cohortKenneth F Adams
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA
Am J Epidemiol 166:36-45. 2007..02). BMI was related to colon cancer risk for younger (aged 50-66 years) but not older (aged 67-71 years) women. The association was not modified by hormone replacement therapy in women or physical activity in men or women...
The association of menstrual and reproductive factors with upper gastrointestinal tract cancers in the NIH-AARP cohortNeal D Freedman
Division of Cancer Epidemiology and Genetics, Nutritional Epidemiology Branch, 6120 Executive Blvd, EPS 320, MSC 7232, Rockville, MD 20852, USA
Cancer 116:1572-81. 2010..Established risk factors do not appear to explain these differences, suggesting a possible role for sex hormones...
A prospective study of meat, cooking methods, meat mutagens, heme iron, and lung cancer risksNatasa Tasevska
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892 7242, USA
Am J Clin Nutr 89:1884-94. 2009..Red and processed meat consumption may play a role in lung cancer pathogenesis because of these meats' fat and carcinogen content...
Breast cancer epidemiology according to recognized breast cancer risk factors in the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial CohortJames V Lacey
Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, MD, USA
BMC Cancer 9:84. 2009..We therefore evaluated known risk factors for breast cancer in a cancer screening trial that does not have breast cancer as a study endpoint but is large enough to provide numerous analytic opportunities for breast cancer...
Prospective study of physical activity and lung cancer by histologic type in current, former, and never smokersMichael F Leitzmann
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD, USA
Am J Epidemiol 169:542-53. 2009..The inverse findings among former and current smokers in combination with the null results for physical activity among never smokers may point toward residual confounding by cigarette smoking as an explanation for the relations observed...
Menopausal hormone therapy and breast cancer risk in the NIH-AARP Diet and Health Study CohortLouise A Brinton
Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, USA
Cancer Epidemiol Biomarkers Prev 17:3150-60. 2008..Results from the Women's Health Initiative trial raise new questions regarding the effects of estrogen therapy (ET) and estrogen plus progestin therapy (EPT) on breast cancer risk...
Physical activity in relation to cardiovascular disease and total mortality among men with type 2 diabetesMihaela Tanasescu
Department of Nutrition, Harvard School of Public Health, Boston, Mass, USA
Circulation 107:2435-9. 2003..CVD risk and mortality are increased in type 2 diabetes. Few epidemiological studies have investigated the effect of physical activity on these outcomes among type 2 diabetics...
A prospective study of red and processed meat intake in relation to cancer riskAmanda J Cross
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland, United States of America
PLoS Med 4:e325. 2007..We investigated whether red or processed meat intake increases cancer risk at a variety of sites...
Fruit and vegetable intake and gastric cancer risk in a large United States prospective cohort studyNeal D Freedman
Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
Cancer Causes Control 19:459-67. 2008..Fruit and vegetable intake may protect against gastric cancer incidence. Results from case-control studies have indicated an inverse association, but results from cohort studies are inconsistent...
Fruits, vegetables, and colon cancer risk in a pooled analysis of 14 cohort studiesAnita Koushik
Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
J Natl Cancer Inst 99:1471-83. 2007..Statistical power to examine associations by colon site has been limited in previous studies...
Prospective study of dietary fiber, whole grain foods, and small intestinal cancerArthur Schatzkin
Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20852, USA
Gastroenterology 135:1163-7. 2008..We conducted a prospective cohort study to determine the relationship between intake of dietary fiber/whole grains and the incidence of small intestinal cancer...
Age-specific physical activity and prostate cancer risk among white men and black menSteven C Moore
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA
Cancer 115:5060-70. 2009..The authors investigated physical activity, including activity during different age periods and of various intensities, in relation to prostate cancer incidence among white men and black men...
A prospective study of meat and fat intake in relation to small intestinal cancerAmanda J Cross
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, Maryland 20852, USA
Cancer Res 68:9274-9. 2008..72; 95% CI, 1.79-7.74 for each 10-g increase in intake per 1,000 kcal). Our findings suggest that the positive associations for meat intake reported in previous case-control studies may partly be explained by saturated fat intake...
Waist circumference as compared with body-mass index in predicting mortality from specific causesMichael F Leitzmann
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, U S Department of Health and Human Services, Bethesda, Maryland, United States of America
PLoS ONE 6:e18582. 2011..Whether waist circumference provides clinically meaningful information not delivered by body-mass index regarding prediction of cause-specific death is uncertain...
Alcohol use and risk of pancreatic cancer: the NIH-AARP Diet and Health StudyLi Jiao
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852, USA
Am J Epidemiol 169:1043-51. 2009..41, 95% CI: 1.01, 2.00). These findings suggest a moderately increased pancreatic cancer risk with heavy alcohol use, particularly liquor; however, residual confounding by cigarette smoking cannot be completely excluded...
Intakes of fruit, vegetables, and carotenoids and renal cell cancer risk: a pooled analysis of 13 prospective studiesJung Eun Lee
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
Cancer Epidemiol Biomarkers Prev 18:1730-9. 2009..13 (0.95-1.34) for lycopene. In conclusion, increasing fruit and vegetable consumption is associated with decreasing risk of renal cell cancer; carotenoids present in fruit and vegetables may partly contribute to this protection...
Calcium, dairy foods, and risk of incident and fatal prostate cancer: the NIH-AARP Diet and Health StudyYikyung Park
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20852, USA
Am J Epidemiol 166:1270-9. 2007..04). Although the authors cannot definitively rule out a weak association for aggressive prostate cancer, their findings do not provide strong support for the hypothesis that calcium and dairy foods increase prostate cancer risk...
Prospective study of adiposity and weight change in relation to prostate cancer incidence and mortalityMargaret E Wright
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
Cancer 109:675-84. 2007..Adiposity has been linked inconsistently with prostate cancer, and few studies have evaluated whether such associations vary by disease aggressiveness...
Dairy products, calcium intake, and risk of prostate cancer in the prostate, lung, colorectal, and ovarian cancer screening trialJiyoung Ahn
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, 6120 Executive Boulevard, Bethesda, MD 20892, USA
Cancer Epidemiol Biomarkers Prev 16:2623-30. 2007..Furthermore, we found no relationship between calcium intake and circulating vitamin D...
Fruit and vegetable intakes and risk of colorectal cancer in the NIH-AARP diet and health studyYikyung Park
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20852, USA
Am J Epidemiol 166:170-80. 2007..the lowest = 0.86, 95% confidence interval: 0.74, 0.99). Intake of fruits was not related to risk of colorectal cancer in men or women...
Prospective investigation of the cigarette smoking-head and neck cancer association by sexNeal D Freedman
Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, Rockville, Maryland 20852, USA
Cancer 110:1593-601. 2007..Very few prospective studies have examined the association between cigarette smoking and cancers of the head and neck in women, even though the rates of smoking in women are increasing rapidly worldwide...
A prospective study of physical activity and the risk of pancreatic cancer among women (United States)Brook A Calton
Division of Cancer Epidemiology and Genetics, NCI NIH, Rockville, MD, USA
BMC Cancer 8:63. 2008..Several epidemiologic studies have examined the association between physical activity and pancreatic cancer risk; however, the results of these studies are not consistent...
Frequent nut consumption and decreased risk of cholecystectomy in womenChung Jyi Tsai
Channing Laboratory, Department of Medicine, Harvard Medical School and Brigham and Women s Hospital, Boston, MA, USA
Am J Clin Nutr 80:76-81. 2004..Gallstone disease is a major source of morbidity in the developed countries. Nuts are rich in several compounds that may protect against gallstone disease...
Body mass index, effect modifiers, and risk of pancreatic cancer: a pooled study of seven prospective cohortsLi Jiao
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
Cancer Causes Control 21:1305-14. 2010..To investigate whether the positive association of body mass index (BMI, kg/m(2)) with risk of pancreatic cancer is modified by age, sex, smoking status, physical activity, and history of diabetes...
A prospective study of physical activity and incident and fatal prostate cancerEdward L Giovannucci
Department of Nutrition, Harvard School of Public Health, Boston, Mass, USA
Arch Intern Med 165:1005-10. 2005..Whether physical activity has benefits against prostate cancer incidence or progression is unclear. Therefore, we assessed physical activity in relation to prostate cancer incidence, mortality, and Gleason histologic grade...
Supplemental and dietary vitamin E intakes and risk of prostate cancer in a large prospective studyMargaret E Wright
Divisions of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, Maryland, USA
Cancer Epidemiol Biomarkers Prev 16:1128-35. 2007..The potential benefit of gamma-tocopherol for prostate cancer prevention deserves further attention...
Physical activity in relation to total, advanced, and fatal prostate cancerSteven C Moore
Division of Cancer Epidemiology, National Cancer Institute, Bethesda, MD 20892, USA
Cancer Epidemiol Biomarkers Prev 17:2458-66. 2008..96; 95% CI, 0.67-1.36; P(trend) = 0.99). Neither vigorous exercise at baseline nor exercise during adolescence was related to risk of total, advanced, or fatal prostate cancer in this large prospective cohort...
Folate intake, alcohol use, and postmenopausal breast cancer risk in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening TrialRachael Z Stolzenberg-Solomon
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Boulevard, Suite 320, Rockville, MD 20852, USA
Am J Clin Nutr 83:895-904. 2006..Several epidemiologic studies suggest that higher folate intakes are associated with lower breast cancer risk, particularly in women with moderate alcohol consumption...
Cigarette smoking and subsequent risk of lung cancer in men and women: analysis of a prospective cohort studyNeal D Freedman
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, 6120 ExecutiveBoulevard, MSC 7232, Rockville, MD 20852, USA
Lancet Oncol 9:649-56. 2008..To address this question, we aimed to compare incidence rates of lung cancer by stratum of smoking use in men and women of the National Institutes of Health (NIH)-AARP cohort...
A prospective study of tobacco, alcohol, and the risk of esophageal and gastric cancer subtypesNeal D Freedman
Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
Am J Epidemiol 165:1424-33. 2007..93, 95% CI: 2.69, 9.03) but not risk for esophageal, gastric cardia, or gastric noncardia adenocarcinoma...
Physical activity and risk of ovarian cancer: a prospective cohort study in the United StatesLindsay M Hannan
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, 6120 Executive Boulevard, EPS-MSC 7232, Bethesda, MD 20892, USA
Cancer Epidemiol Biomarkers Prev 13:765-70. 2004..13). In this prospective cohort study among U.S. women, we found no overall significant association between physical activity and risk of ovarian cancer, although the results are suggestive of an inverse association...
Accelerometer-measured physical activity in Chinese adultsTricia M Peters
National Cancer Institute, Bethesda, Maryland, USA
Am J Prev Med 38:583-91. 2010..Following adoption of a Western lifestyle, China is experiencing a decline in physical activity levels, which is projected to contribute to future increases in the burden of chronic diseases...
Physical activity and breast cancer risk among pre- and postmenopausal women in the U.S. Radiologic Technologists cohortRegan A Howard
Division of Cancer Epidemiology and Genetics, Radiation Epidemiology Branch, National Cancer Institute NIH, Executive Plaza South, Bethesda, MD, 20892, USA
Cancer Causes Control 20:323-33. 2009..Our study suggests moderate intensity physical activity, such as walking, may protect against breast cancer. Further, the relation between physical activity and breast cancer may be modified by MHT use...
Glycemic load, glycemic index, and carbohydrate intake in relation to risk of cholecystectomy in womenChung Jyi Tsai
Channing Laboratory, Department of Medicine, Harvard Medical School and Brigham and Women s Hospital, Boston, Massachusetts, USA
Gastroenterology 129:105-12. 2005..High-carbohydrate diets with a high glycemic response may exacerbate the metabolic consequences of the insulin-resistance syndrome. The effect on the incidence of gallstone disease is not clear...
Dietary protein and the risk of cholecystectomy in a cohort of US women: the Nurses' Health StudyChung Jyi Tsai
Channing Laboratory, Department of Medicine, Harvard Medical School and Brigham and Women s Hospital, Boston, MA, USA
Am J Epidemiol 160:11-8. 2004..These results suggest that increased consumption of vegetable protein in the context of an energy-balanced diet can reduce the risk of cholecystectomy in women...
Physical activity, sedentary behavior, and the risk of colon and rectal cancer in the NIH-AARP Diet and Health StudyRegan A Howard
Division of Cancer Epidemiology and Genetics, Radiation Epidemiology Branch, National Cancer Institute, NIH, DHHS, Bethesda, MD, 20892, USA
Cancer Causes Control 19:939-53. 2008..In order to prospectively investigate physical activity at varying intensities and sedentary behavior in relation to colorectal cancer...
Physical activity and the risk of colon cancer among women: a prospective cohort study (United States)Brook A Calton
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852, USA
Int J Cancer 119:385-91. 2006..The results of this large prospective cohort study among women do not support the hypothesis that physical activity is related to a lower incidence of colon cancer...
Association of energy intake and energy balance with postmenopausal breast cancer in the prostate, lung, colorectal, and ovarian cancer screening trialShih Chen Chang
Division of Cancer Epidemiology and Genetics, Nutritional Epidemiology Branch, National Cancer Institute, Executive Plaza South, Suite 320, MSC7232, Bethesda, Maryland 20892 7232, USA
Cancer Epidemiol Biomarkers Prev 15:334-41. 2006..In addition, these three aspects of energy balance may act jointly in determining breast cancer risk...
Overweight, obesity, and mortality in a large prospective cohort of persons 50 to 71 years oldKenneth F Adams
Nutritional Epidemiology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
N Engl J Med 355:763-78. 2006..0 or more, is associated with an increased risk of death, but the relation between overweight (a BMI of 25.0 to 29.9) and the risk of death has been questioned...
Menopausal hormone therapy and ovarian cancer risk in the National Institutes of Health-AARP Diet and Health Study CohortJames V Lacey
Hormonal and Reproductive Epidemiology Branch, National Cancer Institute, National Institutes of Health, Rockville, MDUSA
J Natl Cancer Inst 98:1397-405. 2006....
Coffee consumption and risk for type 2 diabetes mellitusEduardo Salazar-Martinez
Harvard School of Public Health, Channing Laboratory, Harvard Medical School, and Brigham and Women's Hospital, Boston, Massachusetts 02215, USA
Ann Intern Med 140:1-8. 2004..CONCLUSIONS: These data suggest that long-term coffee consumption is associated with a statistically significantly lower risk for type 2 diabetes...
Nonsteroidal anti-inflammatory drug use and endometrial cancer risk in the NIH-AARP Diet and Health StudyKim N Danforth
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health DHHS, 6120 Executive Boulevard, Rockville, MD 20852, USA
Cancer Prev Res (Phila) 2:466-72. 2009..Overall, our data do not support an association between aspirin or NA-NSAID use and endometrial cancer risk...
A prospective study of dietary alpha-linolenic acid and the risk of prostate cancer (United States)Daniel O Koralek
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD, USA
Cancer Causes Control 17:783-91. 2006..Alpha-linolenic acid (ALA) is the most common omega-3 fatty acid in the Western diet. The relation of dietary intake of ALA to prostate cancer risk remains unresolved...
Joint associations of adiposity and physical activity with mortality: the National Institutes of Health-AARP Diet and Health StudyAnnemarie Koster
Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, Maryland 20892, USA
Am J Epidemiol 169:1344-51. 2009..High physical activity attenuated but did not eliminate the increased mortality risk associated with obesity. Preventing weight gain and promoting physical activity in older persons may lower mortality risk...
Insulin resistance-related gene polymorphisms and risk of prostate cancerSteven C Moore
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland 20892, USA
Cancer Epidemiol Biomarkers Prev 16:1315-7. 2007
Waist circumference and mortalityAnnemarie Koster
Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, MD 20892, USA
Am J Epidemiol 167:1465-75. 2008..36). The finding that persons with a normal BMI but a large waist circumference had a higher mortality risk in this study suggests that increased waist circumference should be considered a risk factor for mortality, in addition to BMI...
A prospective study of lycopene and tomato product intake and risk of prostate cancerVictoria A Kirsh
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Bethesda, MD 20892, USA
Cancer Epidemiol Biomarkers Prev 15:92-8. 2006..Evidence for protective associations in subjects with a family history of prostate cancer requires further corroboration...
A prospective study of serum C-reactive protein and colorectal cancer risk in menMarc J Gunter
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, Maryland 20852, USA
Cancer Res 66:2483-7. 2006..018). These results support the notion that chronic low-grade inflammation is a marker for increased risk of colorectal cancer...
Relationship between calcium, lactose, vitamin D, and dairy products and ovarian cancerDaniel O Koralek
Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
Nutr Cancer 56:22-30. 2006..The possibility of a decreased risk of ovarian cancer for dietary calcium merits further evaluation...
Statin drugs and risk of advanced prostate cancerElizabeth A Platz
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Rm E6138, 615 N Wolfe St, Baltimore, MD 21205, USA
J Natl Cancer Inst 98:1819-25. 2006..We investigated the association of statin use with total and advanced prostate cancer, the latter being the most important endpoint to prevent...
Alcohol intake, drinking patterns, and risk of prostate cancer in a large prospective cohort studyElizabeth A Platz
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
Am J Epidemiol 159:444-53. 2004..64, 95% CI: 1.13, 2.38). These results suggest that moderate or greater alcohol consumption is not a strong contributor to prostate cancer risk, except possibly in men who consume large amounts infrequently...
Interrelation of energy intake, body size, and physical activity with prostate cancer in a large prospective cohort studyElizabeth A Platz
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Heath, The Brady Urological Institute, Baltimore, Maryland 21205, USA
Cancer Res 63:8542-8. 2003....
A prospective cohort study of red wine consumption and risk of prostate cancerSiobhan Sutcliffe
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
Int J Cancer 120:1529-35. 2007..These findings suggest that red wine does not contribute appreciably to the etiology of prostate cancer...
A prospective study of dietary calcium, dairy products and prostate cancer risk (Finland)Panagiota N Mitrou
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD 20852, USA
Int J Cancer 120:2466-73. 2007..The results from this large prospective study suggest that intake of calcium or some related component contained in dairy foods is associated with increased prostate cancer risk...
Aspirin use in relation to risk of prostate cancerMichael F Leitzmann
Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
Cancer Epidemiol Biomarkers Prev 11:1108-11. 2002....
Obesity and colorectal cancer: epidemiology, mechanisms and candidate genesMarc J Gunter
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD 20852, USA
J Nutr Biochem 17:145-56. 2006..These pathways will be discussed with particular reference to genetic polymorphisms that have been associated with obesity and insulin resistance...
Intakes of fruit, vegetables, and specific botanical groups in relation to lung cancer risk in the NIH-AARP Diet and Health StudyMargaret E Wright
Department of Pathology MC 847, College of Medicine, University of Illinois at Chicago, 840 South Wood Street, Room 130, Chicago, IL 60612, USA
Am J Epidemiol 168:1024-34. 2008..06). These results provide support for a protective role of specific botanical subgroups of fruits and vegetables in lung cancer prevention in men, although the findings could also be due to residual confounding by smoking or chance...
Sex steroid hormones and the androgen receptor gene CAG repeat and subsequent risk of prostate cancer in the prostate-specific antigen eraElizabeth A Platz
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Room E6138, 615 North Wolfe Street, Baltimore, MD 21205, USA
Cancer Epidemiol Biomarkers Prev 14:1262-9. 2005..We investigated plasma levels of sex steroid hormones and length of the androgen receptor gene CAG repeat in relation to incident prostate cancer diagnosed in the prostate-specific antigen (PSA) era...
Long-term intake of trans-fatty acids and risk of gallstone disease in menChung Jyi Tsai
Division of Digestive Diseases and Nutrition, University of Kentucky Medical Center, Lexington 40536 0298, USA
Arch Intern Med 165:1011-5. 2005..The consumption of trans-fatty acids adversely affects blood lipid levels. The relationship with the incidence of gallstone disease is unknown...
Serum lycopene, other carotenoids, and prostate cancer risk: a nested case-control study in the prostate, lung, colorectal, and ovarian cancer screening trialUlrike Peters
Cancer Prevention Program, Fred Hutchinson Cancer Research Center, P O Box 19024, 1100 Fairview Avenue North M4 B402, Seattle, WA 98109 1024, USA
Cancer Epidemiol Biomarkers Prev 16:962-8. 2007..This has stimulated extensive laboratory and clinical research, as well as much commercial and public enthusiasm. However, the epidemiologic evidence remains inconclusive...
Weight cycling and risk of gallstone disease in menChung Jyi Tsai
Division of Digestive Diseases and Nutrition, University of Kentucky Medical Center, Lexington, KY 40536 0298, USA
Arch Intern Med 166:2369-74. 2006..The long-term effect of repeated intentional weight loss and weight regain on the risk of gallstone disease in men is not clear...
Prospective study of abdominal adiposity and gallstone disease in US menChung Jyi Tsai
Channing Laboratory, Department of Medicine, Harvard Medical School and Brigham and Women s Hospital, Boston, MA, USA
Am J Clin Nutr 80:38-44. 2004..Obesity is an established risk factor for gallstones, but whether abdominal adiposity contributes independently to the risk, particularly in men, remains unclear...
Multivitamin use and risk of prostate cancer in the National Institutes of Health-AARP Diet and Health StudyKarla A Lawson
Division of Cancer Prevention, National Cancer Institute, Bethesda, MD, USA
J Natl Cancer Inst 99:754-64. 2007..Multivitamin supplements are used by millions of Americans because of their potential health benefits, but the relationship between multivitamin use and prostate cancer is unclear...
Physical activity and renal cell cancer risk in a cohort of male smokersSomdat Mahabir
Cancer Prevention Studies Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA
Int J Cancer 108:600-5. 2004..18-1.13) (p-value for trend = 0.12). Occupational physical activity was unrelated to renal cell cancer risk. These data suggest that recreational physical activity may play a role in the prevention of renal cell cancer in men...
