Michael F Leitzmann

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Dietary intake of n-3 and n-6 fatty acids and the risk of prostate cancer
    Michael F Leitzmann
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    Am J Clin Nutr 80:204-16. 2004
  2. ncbi request reprint Physical activity recommendations and decreased risk of mortality
    Michael F Leitzmann
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
    Arch Intern Med 167:2453-60. 2007
  3. pmc Physical activity and head and neck cancer risk
    Michael F Leitzmann
    Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Cancer Causes Control 19:1391-9. 2008
  4. ncbi request reprint Is there a link between macronutrient intake and prostate cancer?
    Michael F Leitzmann
    Nutritional Epidemiology Branch, US National Cancer Institute, Bethesda, MD 20892, USA
    Nat Clin Pract Oncol 2:184-5. 2005
  5. ncbi request reprint Thiazide diuretics and the risk of gallbladder disease requiring surgery in women
    Michael F Leitzmann
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, EPS MSC 7232, 6120 Executive Boulevard, Bethesda, MD 20892, USA
    Arch Intern Med 165:567-73. 2005
  6. ncbi request reprint Ejaculation frequency and subsequent risk of prostate cancer
    Michael F Leitzmann
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    JAMA 291:1578-86. 2004
  7. ncbi request reprint Zinc supplement use and risk of prostate cancer
    Michael F Leitzmann
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    J Natl Cancer Inst 95:1004-7. 2003
  8. ncbi request reprint Alcohol consumption in relation to risk of cholecystectomy in women
    Michael F Leitzmann
    Department of Nutrition, Harvard School of Public Health, Boston, USA
    Am J Clin Nutr 78:339-47. 2003
  9. pmc Fat, protein, and meat consumption and renal cell cancer risk: a pooled analysis of 13 prospective studies
    Jung Eun Lee
    Channing Laboratory, Brigham and Women s Hospital, and Harvard Medical School, Boston, MA 02115, USA
    J Natl Cancer Inst 100:1695-706. 2008
  10. pmc Body mass index and risk of ovarian cancer
    Michael F Leitzmann
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
    Cancer 115:812-22. 2009

Collaborators

Detail Information

Publications97

  1. ncbi request reprint Dietary intake of n-3 and n-6 fatty acids and the risk of prostate cancer
    Michael F Leitzmann
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    Am J Clin Nutr 80:204-16. 2004
    ..Laboratory studies have shown that n-3 fatty acids inhibit and n-6 fatty acids stimulate prostate tumor growth, but whether the dietary intake of these fatty acids affects prostate cancer risk in humans remains unclear...
  2. ncbi request reprint Physical activity recommendations and decreased risk of mortality
    Michael F Leitzmann
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
    Arch Intern Med 167:2453-60. 2007
    ..Whether national physical activity recommendations are related to mortality benefit is incompletely understood...
  3. pmc Physical activity and head and neck cancer risk
    Michael F Leitzmann
    Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Cancer Causes Control 19:1391-9. 2008
    ..To investigate the relation of physical activity to head and neck cancer...
  4. ncbi request reprint Is there a link between macronutrient intake and prostate cancer?
    Michael F Leitzmann
    Nutritional Epidemiology Branch, US National Cancer Institute, Bethesda, MD 20892, USA
    Nat Clin Pract Oncol 2:184-5. 2005
  5. ncbi request reprint Thiazide diuretics and the risk of gallbladder disease requiring surgery in women
    Michael F Leitzmann
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, EPS MSC 7232, 6120 Executive Boulevard, Bethesda, MD 20892, USA
    Arch Intern Med 165:567-73. 2005
    ..Previous studies have suggested that thiazide diuretic use increases the risk of cholecystitis...
  6. ncbi request reprint Ejaculation frequency and subsequent risk of prostate cancer
    Michael F Leitzmann
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    JAMA 291:1578-86. 2004
    ....
  7. ncbi request reprint Zinc supplement use and risk of prostate cancer
    Michael F Leitzmann
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    J Natl Cancer Inst 95:1004-7. 2003
    ....
  8. ncbi request reprint Alcohol consumption in relation to risk of cholecystectomy in women
    Michael F Leitzmann
    Department of Nutrition, Harvard School of Public Health, Boston, USA
    Am J Clin Nutr 78:339-47. 2003
    ..However, the magnitude of the association is uncertain, and little is known about the relation of alcohol consumption patterns and individual types of alcoholic beverages to gallstone disease risk...
  9. pmc Fat, protein, and meat consumption and renal cell cancer risk: a pooled analysis of 13 prospective studies
    Jung Eun Lee
    Channing Laboratory, Brigham and Women s Hospital, and Harvard Medical School, Boston, MA 02115, USA
    J Natl Cancer Inst 100:1695-706. 2008
    ....
  10. pmc Body mass index and risk of ovarian cancer
    Michael F Leitzmann
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
    Cancer 115:812-22. 2009
    ..However, to the authors' knowledge, data addressing whether the relation between BMI and ovarian cancer differs by MHT use are very sparse...
  11. pmc Intakes of vitamins A, C, and E and use of multiple vitamin supplements and risk of colon cancer: a pooled analysis of prospective cohort studies
    Yikyung Park
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Cancer Causes Control 21:1745-57. 2010
    ..To evaluate the associations between intakes of vitamins A, C, and E and risk of colon cancer...
  12. pmc Alcohol and risk of breast cancer by histologic type and hormone receptor status in postmenopausal women: the NIH-AARP Diet and Health Study
    Jasmine Q Lew
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, Rockville, MD 20852, USA
    Am J Epidemiol 170:308-17. 2009
    ..13 (95% CI: 0.73, 1.77) for >20 g versus 0 g/day, and 1.21 (95% CI: 0.79, 1.84) for >20 g versus 0 g/day, respectively. Moderate consumption of alcohol was associated with breast cancer, specifically hormone receptor-positive tumors...
  13. ncbi request reprint Adiposity, adult weight change, and postmenopausal breast cancer risk
    Jiyoung Ahn
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, EPS, 6120 Executive Blvd, Bethesda, MD 20892, USA
    Arch Intern Med 167:2091-102. 2007
    ..Obesity is a risk factor for postmenopausal breast cancer, but the role of the timing and amount of adult weight change in breast cancer risk is unclear...
  14. pmc Body size and renal cell cancer incidence in a large US cohort study
    Kenneth F Adams
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA
    Am J Epidemiol 168:268-77. 2008
    ..Waist-to hip ratio was positively associated with RCC in women and with height at age 18 years in both men and women...
  15. pmc Adipokine genes and prostate cancer risk
    Steven C Moore
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    Int J Cancer 124:869-76. 2009
    ..05). Polymorphisms in the IL6, LEPR, TNF and ADIPOQ genes were not associated with prostate cancer. Allelic variants in the LEP gene are related to prostate cancer risk, supporting a role for leptin in prostate carcinogenesis...
  16. pmc The combined relations of adiposity and smoking on mortality
    Annemarie Koster
    Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, MD 20892, USA
    Am J Clin Nutr 88:1206-12. 2008
    ..Smoking cessation is associated with increased body weight and a substantial increase in waist circumference. How this affects mortality risk is unknown...
  17. pmc Prospective study of physical activity and risk of postmenopausal breast cancer
    Michael F Leitzmann
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    Breast Cancer Res 10:R92. 2008
    ..To prospectively examine the relation of total, vigorous and non-vigorous physical activity to postmenopausal breast cancer risk...
  18. doi request reprint Diabetes mellitus and prostate cancer risk in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial
    Michael F Leitzmann
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD 20892, USA
    Cancer Causes Control 19:1267-76. 2008
    ....
  19. pmc Physical activity, sedentary behavior, and endometrial cancer risk in the NIH-AARP Diet and Health Study
    Gretchen L Gierach
    Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD 20852 7234, USA
    Int J Cancer 124:2139-47. 2009
    ..02). Associations with vigorous activities, which may interact with body mass index, suggest directions for future research to clarify underlying biologic mechanisms, including those relating to hormonal alterations...
  20. ncbi request reprint Fruit and vegetable intake and esophageal cancer in a large prospective cohort study
    Neal D Freedman
    Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Int J Cancer 121:2753-60. 2007
    ..A significant inverse association between EAC and Chenopodiaceae (spinach) intake was observed. Results from our study suggest that the relation of fruit and vegetable intake and esophageal cancer risk may vary by histologic type...
  21. pmc Physical activity during adulthood and adolescence in relation to renal cell cancer
    Steven C Moore
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
    Am J Epidemiol 168:149-57. 2008
    ..82 (95% CI: 0.68, 1.00; p(trend) = 0.05) for activity during adolescence. The authors conclude that increased physical activity, including activity during adolescence, is associated with reduced risk of renal cell cancer...
  22. pmc Dairy food, calcium, and risk of cancer in the NIH-AARP Diet and Health Study
    Yikyung Park
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Bethesda, MD 20852, USA
    Arch Intern Med 169:391-401. 2009
    ..Dairy food and calcium intakes have been hypothesized to play roles that differ among individual cancer sites, but the evidence has been limited and inconsistent. Moreover, their effect on cancer in total is unclear...
  23. ncbi request reprint Endometrial cancer and menopausal hormone therapy in the National Institutes of Health-AARP Diet and Health Study cohort
    James V Lacey
    Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland, USA
    Cancer 109:1303-11. 2007
    ....
  24. ncbi request reprint Prospective study of alcohol drinking and renal cell cancer risk in a cohort of finnish male smokers
    Somdat Mahabir
    Cancer Prevention Studies Branch, Center for Cancer Research, National Cancer Institute, 6116 Executive Boulevard, Suite 705, MSC 8314, Bethesda, MD 20892 7058, USA
    Cancer Epidemiol Biomarkers Prev 14:170-5. 2005
    ..Because most of the risk reductions were seen at the highest quartile of alcohol intake and alcohol is a risk factor for a number of cancers particularly among smokers, these data should be interpreted with caution...
  25. ncbi request reprint Dietary fiber and whole-grain consumption in relation to colorectal cancer in the NIH-AARP Diet and Health Study
    Arthur Schatzkin
    Division of Cancer Epidemiology, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
    Am J Clin Nutr 85:1353-60. 2007
    ..Whether the intake of dietary fiber can protect against colorectal cancer is a long-standing question of considerable public health import, but the epidemiologic evidence has been inconsistent...
  26. pmc Physical activity and postmenopausal breast cancer risk in the NIH-AARP diet and health study
    Tricia M Peters
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, 6120 Executive Boulevard, MSC 7232, Bethesda, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 18:289-96. 2009
    ..Although physical activity has been associated with reduced breast cancer risk, whether this association varies across breast cancer subtypes or is modified by reproductive and lifestyle factors is unclear...
  27. pmc Beyond recreational physical activity: examining occupational and household activity, transportation activity, and sedentary behavior in relation to postmenopausal breast cancer risk
    Stephanie M George
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA
    Am J Public Health 100:2288-95. 2010
    ..We prospectively examined nonrecreational physical activity and sedentary behavior in relation to breast cancer risk among 97 039 postmenopausal women in the National Institutes of Health-AARP Diet and Health Study...
  28. pmc Intensity and timing of physical activity in relation to postmenopausal breast cancer risk: the prospective NIH-AARP diet and health study
    Tricia M Peters
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, 6120 Executive Blvd, Bethesda, MD, USA
    BMC Cancer 9:349. 2009
    ..Despite strong evidence of an inverse association of physical activity with postmenopausal breast cancer risk, whether a certain intensity or time of life of physical activity is most effective for lowering breast cancer risk is not known...
  29. ncbi request reprint Lifetime weight history and endometrial cancer risk by type of menopausal hormone use in the NIH-AARP diet and health study
    Shih Chen Chang
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Suite 320, Executive Plaza South, MSC7232, Bethesda, MD 20892 7232, USA
    Cancer Epidemiol Biomarkers Prev 16:723-30. 2007
    ..We conclude that both current adiposity and adult weight gain are associated with substantial increases in the risk of endometrial cancer, with relations particularly evident among never users of menopausal hormone therapy...
  30. ncbi request reprint Fruit and vegetable intake and head and neck cancer risk in a large United States prospective cohort study
    Neal D Freedman
    Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Int J Cancer 122:2330-6. 2008
    ..Results from this large prospective observational study are consistent with previous case-control studies and support the hypothesis that total fruit and vegetable intake is associated with reduced risk of head and neck cancer...
  31. pmc Nonsteroidal anti-inflammatory drugs and breast cancer risk in the National Institutes of Health-AARP Diet and Health Study
    Gretchen L Gierach
    Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Blvd, Suite 550, Rockville, MD 20852 7234, USA
    Breast Cancer Res 10:R38. 2008
    ..Epidemiologic evidence for a protective role of NSAIDs in breast cancer, however, is equivocal...
  32. pmc Added sugar and sugar-sweetened foods and beverages and the risk of pancreatic cancer in the National Institutes of Health-AARP Diet and Health Study
    Ying Bao
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Am J Clin Nutr 88:431-40. 2008
    ..Although it has been hypothesized that hyperglycemia, hyperinsulinemia, and insulin resistance are involved in the development of pancreatic cancer, results from epidemiologic studies of added sugar intake are inconclusive...
  33. ncbi request reprint Body mass and colorectal cancer risk in the NIH-AARP cohort
    Kenneth F Adams
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA
    Am J Epidemiol 166:36-45. 2007
    ..02). BMI was related to colon cancer risk for younger (aged 50-66 years) but not older (aged 67-71 years) women. The association was not modified by hormone replacement therapy in women or physical activity in men or women...
  34. pmc Physical activity and esophageal and gastric carcinoma in a large prospective study
    Michael F Leitzmann
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
    Am J Prev Med 36:112-9. 2009
    ..Few studies have investigated the relationship of physical activity to esophageal and gastric carcinoma according to histology and anatomic site...
  35. ncbi request reprint Fruits, vegetables, and colon cancer risk in a pooled analysis of 14 cohort studies
    Anita Koushik
    Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
    J Natl Cancer Inst 99:1471-83. 2007
    ..Statistical power to examine associations by colon site has been limited in previous studies...
  36. pmc A prospective study of meat, cooking methods, meat mutagens, heme iron, and lung cancer risks
    Natasa Tasevska
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892 7242, USA
    Am J Clin Nutr 89:1884-94. 2009
    ..Red and processed meat consumption may play a role in lung cancer pathogenesis because of these meats' fat and carcinogen content...
  37. pmc Prospective study of physical activity and lung cancer by histologic type in current, former, and never smokers
    Michael F Leitzmann
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD, USA
    Am J Epidemiol 169:542-53. 2009
    ..The inverse findings among former and current smokers in combination with the null results for physical activity among never smokers may point toward residual confounding by cigarette smoking as an explanation for the relations observed...
  38. pmc Breast cancer epidemiology according to recognized breast cancer risk factors in the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial Cohort
    James V Lacey
    Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, MD, USA
    BMC Cancer 9:84. 2009
    ..We therefore evaluated known risk factors for breast cancer in a cancer screening trial that does not have breast cancer as a study endpoint but is large enough to provide numerous analytic opportunities for breast cancer...
  39. pmc The association of menstrual and reproductive factors with upper gastrointestinal tract cancers in the NIH-AARP cohort
    Neal D Freedman
    Division of Cancer Epidemiology and Genetics, Nutritional Epidemiology Branch, 6120 Executive Blvd, EPS 320, MSC 7232, Rockville, MD 20852, USA
    Cancer 116:1572-81. 2010
    ..Established risk factors do not appear to explain these differences, suggesting a possible role for sex hormones...
  40. pmc Menopausal hormone therapy and breast cancer risk in the NIH-AARP Diet and Health Study Cohort
    Louise A Brinton
    Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, USA
    Cancer Epidemiol Biomarkers Prev 17:3150-60. 2008
    ..Results from the Women's Health Initiative trial raise new questions regarding the effects of estrogen therapy (ET) and estrogen plus progestin therapy (EPT) on breast cancer risk...
  41. ncbi request reprint Physical activity in relation to cardiovascular disease and total mortality among men with type 2 diabetes
    Mihaela Tanasescu
    Department of Nutrition, Harvard School of Public Health, Boston, Mass, USA
    Circulation 107:2435-9. 2003
    ..CVD risk and mortality are increased in type 2 diabetes. Few epidemiological studies have investigated the effect of physical activity on these outcomes among type 2 diabetics...
  42. pmc A prospective study of physical activity and the risk of pancreatic cancer among women (United States)
    Brook A Calton
    Division of Cancer Epidemiology and Genetics, NCI NIH, Rockville, MD, USA
    BMC Cancer 8:63. 2008
    ..Several epidemiologic studies have examined the association between physical activity and pancreatic cancer risk; however, the results of these studies are not consistent...
  43. ncbi request reprint Dairy products, calcium intake, and risk of prostate cancer in the prostate, lung, colorectal, and ovarian cancer screening trial
    Jiyoung Ahn
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, 6120 Executive Boulevard, Bethesda, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 16:2623-30. 2007
    ..Furthermore, we found no relationship between calcium intake and circulating vitamin D...
  44. doi request reprint Fruit and vegetable intake and gastric cancer risk in a large United States prospective cohort study
    Neal D Freedman
    Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Cancer Causes Control 19:459-67. 2008
    ..Fruit and vegetable intake may protect against gastric cancer incidence. Results from case-control studies have indicated an inverse association, but results from cohort studies are inconsistent...
  45. pmc Prospective study of dietary fiber, whole grain foods, and small intestinal cancer
    Arthur Schatzkin
    Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20852, USA
    Gastroenterology 135:1163-7. 2008
    ..We conducted a prospective cohort study to determine the relationship between intake of dietary fiber/whole grains and the incidence of small intestinal cancer...
  46. pmc Age-specific physical activity and prostate cancer risk among white men and black men
    Steven C Moore
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA
    Cancer 115:5060-70. 2009
    ..The authors investigated physical activity, including activity during different age periods and of various intensities, in relation to prostate cancer incidence among white men and black men...
  47. pmc A prospective study of meat and fat intake in relation to small intestinal cancer
    Amanda J Cross
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, Maryland 20852, USA
    Cancer Res 68:9274-9. 2008
    ..72; 95% CI, 1.79-7.74 for each 10-g increase in intake per 1,000 kcal). Our findings suggest that the positive associations for meat intake reported in previous case-control studies may partly be explained by saturated fat intake...
  48. pmc Waist circumference as compared with body-mass index in predicting mortality from specific causes
    Michael F Leitzmann
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, U S Department of Health and Human Services, Bethesda, Maryland, United States of America
    PLoS ONE 6:e18582. 2011
    ..Whether waist circumference provides clinically meaningful information not delivered by body-mass index regarding prediction of cause-specific death is uncertain...
  49. pmc Alcohol use and risk of pancreatic cancer: the NIH-AARP Diet and Health Study
    Li Jiao
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852, USA
    Am J Epidemiol 169:1043-51. 2009
    ..41, 95% CI: 1.01, 2.00). These findings suggest a moderately increased pancreatic cancer risk with heavy alcohol use, particularly liquor; however, residual confounding by cigarette smoking cannot be completely excluded...
  50. pmc Intakes of fruit, vegetables, and carotenoids and renal cell cancer risk: a pooled analysis of 13 prospective studies
    Jung Eun Lee
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 18:1730-9. 2009
    ..13 (0.95-1.34) for lycopene. In conclusion, increasing fruit and vegetable consumption is associated with decreasing risk of renal cell cancer; carotenoids present in fruit and vegetables may partly contribute to this protection...
  51. pmc A prospective study of red and processed meat intake in relation to cancer risk
    Amanda J Cross
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland, United States of America
    PLoS Med 4:e325. 2007
    ..We investigated whether red or processed meat intake increases cancer risk at a variety of sites...
  52. ncbi request reprint Prospective investigation of the cigarette smoking-head and neck cancer association by sex
    Neal D Freedman
    Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, Rockville, Maryland 20852, USA
    Cancer 110:1593-601. 2007
    ..Very few prospective studies have examined the association between cigarette smoking and cancers of the head and neck in women, even though the rates of smoking in women are increasing rapidly worldwide...
  53. ncbi request reprint Calcium, dairy foods, and risk of incident and fatal prostate cancer: the NIH-AARP Diet and Health Study
    Yikyung Park
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20852, USA
    Am J Epidemiol 166:1270-9. 2007
    ..04). Although the authors cannot definitively rule out a weak association for aggressive prostate cancer, their findings do not provide strong support for the hypothesis that calcium and dairy foods increase prostate cancer risk...
  54. ncbi request reprint Fruit and vegetable intakes and risk of colorectal cancer in the NIH-AARP diet and health study
    Yikyung Park
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20852, USA
    Am J Epidemiol 166:170-80. 2007
    ..the lowest = 0.86, 95% confidence interval: 0.74, 0.99). Intake of fruits was not related to risk of colorectal cancer in men or women...
  55. pmc Accelerometer-measured physical activity in Chinese adults
    Tricia M Peters
    National Cancer Institute, Bethesda, Maryland, USA
    Am J Prev Med 38:583-91. 2010
    ..Following adoption of a Western lifestyle, China is experiencing a decline in physical activity levels, which is projected to contribute to future increases in the burden of chronic diseases...
  56. ncbi request reprint Prospective study of adiposity and weight change in relation to prostate cancer incidence and mortality
    Margaret E Wright
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
    Cancer 109:675-84. 2007
    ..Adiposity has been linked inconsistently with prostate cancer, and few studies have evaluated whether such associations vary by disease aggressiveness...
  57. ncbi request reprint Folate intake, alcohol use, and postmenopausal breast cancer risk in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial
    Rachael Z Stolzenberg-Solomon
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Boulevard, Suite 320, Rockville, MD 20852, USA
    Am J Clin Nutr 83:895-904. 2006
    ..Several epidemiologic studies suggest that higher folate intakes are associated with lower breast cancer risk, particularly in women with moderate alcohol consumption...
  58. ncbi request reprint Supplemental and dietary vitamin E intakes and risk of prostate cancer in a large prospective study
    Margaret E Wright
    Divisions of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, Maryland, USA
    Cancer Epidemiol Biomarkers Prev 16:1128-35. 2007
    ..The potential benefit of gamma-tocopherol for prostate cancer prevention deserves further attention...
  59. pmc Cigarette smoking and subsequent risk of lung cancer in men and women: analysis of a prospective cohort study
    Neal D Freedman
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, 6120 ExecutiveBoulevard, MSC 7232, Rockville, MD 20852, USA
    Lancet Oncol 9:649-56. 2008
    ..To address this question, we aimed to compare incidence rates of lung cancer by stratum of smoking use in men and women of the National Institutes of Health (NIH)-AARP cohort...
  60. ncbi request reprint A prospective study of physical activity and incident and fatal prostate cancer
    Edward L Giovannucci
    Department of Nutrition, Harvard School of Public Health, Boston, Mass, USA
    Arch Intern Med 165:1005-10. 2005
    ..Whether physical activity has benefits against prostate cancer incidence or progression is unclear. Therefore, we assessed physical activity in relation to prostate cancer incidence, mortality, and Gleason histologic grade...
  61. ncbi request reprint Frequent nut consumption and decreased risk of cholecystectomy in women
    Chung Jyi Tsai
    Channing Laboratory, Department of Medicine, Harvard Medical School and Brigham and Women s Hospital, Boston, MA, USA
    Am J Clin Nutr 80:76-81. 2004
    ..Gallstone disease is a major source of morbidity in the developed countries. Nuts are rich in several compounds that may protect against gallstone disease...
  62. pmc Body mass index, effect modifiers, and risk of pancreatic cancer: a pooled study of seven prospective cohorts
    Li Jiao
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Cancer Causes Control 21:1305-14. 2010
    ..To investigate whether the positive association of body mass index (BMI, kg/m(2)) with risk of pancreatic cancer is modified by age, sex, smoking status, physical activity, and history of diabetes...
  63. pmc Physical activity in relation to total, advanced, and fatal prostate cancer
    Steven C Moore
    Division of Cancer Epidemiology, National Cancer Institute, Bethesda, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 17:2458-66. 2008
    ..96; 95% CI, 0.67-1.36; P(trend) = 0.99). Neither vigorous exercise at baseline nor exercise during adolescence was related to risk of total, advanced, or fatal prostate cancer in this large prospective cohort...
  64. ncbi request reprint Physical activity and risk of ovarian cancer: a prospective cohort study in the United States
    Lindsay M Hannan
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, 6120 Executive Boulevard, EPS MSC 7232, Bethesda, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 13:765-70. 2004
    ..13). In this prospective cohort study among U.S. women, we found no overall significant association between physical activity and risk of ovarian cancer, although the results are suggestive of an inverse association...
  65. ncbi request reprint A prospective study of tobacco, alcohol, and the risk of esophageal and gastric cancer subtypes
    Neal D Freedman
    Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
    Am J Epidemiol 165:1424-33. 2007
    ..93, 95% CI: 2.69, 9.03) but not risk for esophageal, gastric cardia, or gastric noncardia adenocarcinoma...
  66. pmc Physical activity and breast cancer risk among pre- and postmenopausal women in the U.S. Radiologic Technologists cohort
    Regan A Howard
    Division of Cancer Epidemiology and Genetics, Radiation Epidemiology Branch, National Cancer Institute NIH, Executive Plaza South, Bethesda, MD, 20892, USA
    Cancer Causes Control 20:323-33. 2009
    ..Our study suggests moderate intensity physical activity, such as walking, may protect against breast cancer. Further, the relation between physical activity and breast cancer may be modified by MHT use...
  67. ncbi request reprint Dietary protein and the risk of cholecystectomy in a cohort of US women: the Nurses' Health Study
    Chung Jyi Tsai
    Channing Laboratory, Department of Medicine, Harvard Medical School and Brigham and Women s Hospital, Boston, MA, USA
    Am J Epidemiol 160:11-8. 2004
    ..These results suggest that increased consumption of vegetable protein in the context of an energy-balanced diet can reduce the risk of cholecystectomy in women...
  68. ncbi request reprint Glycemic load, glycemic index, and carbohydrate intake in relation to risk of cholecystectomy in women
    Chung Jyi Tsai
    Channing Laboratory, Department of Medicine, Harvard Medical School and Brigham and Women s Hospital, Boston, Massachusetts, USA
    Gastroenterology 129:105-12. 2005
    ..High-carbohydrate diets with a high glycemic response may exacerbate the metabolic consequences of the insulin-resistance syndrome. The effect on the incidence of gallstone disease is not clear...
  69. ncbi request reprint Physical activity and the risk of colon cancer among women: a prospective cohort study (United States)
    Brook A Calton
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852, USA
    Int J Cancer 119:385-91. 2006
    ..The results of this large prospective cohort study among women do not support the hypothesis that physical activity is related to a lower incidence of colon cancer...
  70. pmc Physical activity, sedentary behavior, and the risk of colon and rectal cancer in the NIH-AARP Diet and Health Study
    Regan A Howard
    Division of Cancer Epidemiology and Genetics, Radiation Epidemiology Branch, National Cancer Institute, NIH, DHHS, Bethesda, MD, 20892, USA
    Cancer Causes Control 19:939-53. 2008
    ..In order to prospectively investigate physical activity at varying intensities and sedentary behavior in relation to colorectal cancer...
  71. doi request reprint Waist circumference and mortality
    Annemarie Koster
    Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, MD 20892, USA
    Am J Epidemiol 167:1465-75. 2008
    ..36). The finding that persons with a normal BMI but a large waist circumference had a higher mortality risk in this study suggests that increased waist circumference should be considered a risk factor for mortality, in addition to BMI...
  72. ncbi request reprint Overweight, obesity, and mortality in a large prospective cohort of persons 50 to 71 years old
    Kenneth F Adams
    Nutritional Epidemiology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    N Engl J Med 355:763-78. 2006
    ..0 or more, is associated with an increased risk of death, but the relation between overweight (a BMI of 25.0 to 29.9) and the risk of death has been questioned...
  73. ncbi request reprint Coffee consumption and risk for type 2 diabetes mellitus
    Eduardo Salazar-Martinez
    Harvard School of Public Health, Channing Laboratory, Harvard Medical School, and Brigham and Women s Hospital, Boston, Massachusetts 02215, USA
    Ann Intern Med 140:1-8. 2004
    ..In small, short-term studies, acute administration of caffeine decreases insulin sensitivity and impairs glucose tolerance...
  74. ncbi request reprint Menopausal hormone therapy and ovarian cancer risk in the National Institutes of Health-AARP Diet and Health Study Cohort
    James V Lacey
    Hormonal and Reproductive Epidemiology Branch, National Cancer Institute, National Institutes of Health, Rockville, MDUSA
    J Natl Cancer Inst 98:1397-405. 2006
    ....
  75. pmc Nonsteroidal anti-inflammatory drug use and endometrial cancer risk in the NIH-AARP Diet and Health Study
    Kim N Danforth
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health DHHS, 6120 Executive Boulevard, Rockville, MD 20852, USA
    Cancer Prev Res (Phila) 2:466-72. 2009
    ..Overall, our data do not support an association between aspirin or NA-NSAID use and endometrial cancer risk...
  76. pmc Joint associations of adiposity and physical activity with mortality: the National Institutes of Health-AARP Diet and Health Study
    Annemarie Koster
    Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, Maryland 20892, USA
    Am J Epidemiol 169:1344-51. 2009
    ..High physical activity attenuated but did not eliminate the increased mortality risk associated with obesity. Preventing weight gain and promoting physical activity in older persons may lower mortality risk...
  77. ncbi request reprint Insulin resistance-related gene polymorphisms and risk of prostate cancer
    Steven C Moore
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland 20892, USA
    Cancer Epidemiol Biomarkers Prev 16:1315-7. 2007
  78. ncbi request reprint A prospective study of dietary alpha-linolenic acid and the risk of prostate cancer (United States)
    Daniel O Koralek
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD, USA
    Cancer Causes Control 17:783-91. 2006
    ..Alpha-linolenic acid (ALA) is the most common omega-3 fatty acid in the Western diet. The relation of dietary intake of ALA to prostate cancer risk remains unresolved...
  79. ncbi request reprint A prospective study of lycopene and tomato product intake and risk of prostate cancer
    Victoria A Kirsh
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Bethesda, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 15:92-8. 2006
    ..Dietary lycopene and tomato products may reduce risk of prostate cancer; however, uncertainty remains about this possible association...
  80. ncbi request reprint A prospective study of serum C-reactive protein and colorectal cancer risk in men
    Marc J Gunter
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, Maryland 20852, USA
    Cancer Res 66:2483-7. 2006
    ..018). These results support the notion that chronic low-grade inflammation is a marker for increased risk of colorectal cancer...
  81. ncbi request reprint Association of energy intake and energy balance with postmenopausal breast cancer in the prostate, lung, colorectal, and ovarian cancer screening trial
    Shih Chen Chang
    Division of Cancer Epidemiology and Genetics, Nutritional Epidemiology Branch, National Cancer Institute, Executive Plaza South, Suite 320, MSC7232, Bethesda, Maryland 20892 7232, USA
    Cancer Epidemiol Biomarkers Prev 15:334-41. 2006
    ..In addition, these three aspects of energy balance may act jointly in determining breast cancer risk...
  82. ncbi request reprint Relationship between calcium, lactose, vitamin D, and dairy products and ovarian cancer
    Daniel O Koralek
    Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Nutr Cancer 56:22-30. 2006
    ..The possibility of a decreased risk of ovarian cancer for dietary calcium merits further evaluation...
  83. ncbi request reprint A prospective cohort study of red wine consumption and risk of prostate cancer
    Siobhan Sutcliffe
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Int J Cancer 120:1529-35. 2007
    ..These findings suggest that red wine does not contribute appreciably to the etiology of prostate cancer...
  84. ncbi request reprint Alcohol intake, drinking patterns, and risk of prostate cancer in a large prospective cohort study
    Elizabeth A Platz
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Am J Epidemiol 159:444-53. 2004
    ..64, 95% CI: 1.13, 2.38). These results suggest that moderate or greater alcohol consumption is not a strong contributor to prostate cancer risk, except possibly in men who consume large amounts infrequently...
  85. ncbi request reprint Interrelation of energy intake, body size, and physical activity with prostate cancer in a large prospective cohort study
    Elizabeth A Platz
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Heath, The Brady Urological Institute, Baltimore, Maryland 21205, USA
    Cancer Res 63:8542-8. 2003
    ....
  86. ncbi request reprint A prospective study of dietary calcium, dairy products and prostate cancer risk (Finland)
    Panagiota N Mitrou
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD 20852, USA
    Int J Cancer 120:2466-73. 2007
    ..The results from this large prospective study suggest that intake of calcium or some related component contained in dairy foods is associated with increased prostate cancer risk...
  87. ncbi request reprint Multivitamin use and risk of prostate cancer in the National Institutes of Health-AARP Diet and Health Study
    Karla A Lawson
    Division of Cancer Prevention, National Cancer Institute, Bethesda, MD, USA
    J Natl Cancer Inst 99:754-64. 2007
    ..Multivitamin supplements are used by millions of Americans because of their potential health benefits, but the relationship between multivitamin use and prostate cancer is unclear...
  88. ncbi request reprint Aspirin use in relation to risk of prostate cancer
    Michael F Leitzmann
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Cancer Epidemiol Biomarkers Prev 11:1108-11. 2002
    ....
  89. ncbi request reprint Statin drugs and risk of advanced prostate cancer
    Elizabeth A Platz
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Rm E6138, 615 N Wolfe St, Baltimore, MD 21205, USA
    J Natl Cancer Inst 98:1819-25. 2006
    ..We investigated the association of statin use with total and advanced prostate cancer, the latter being the most important endpoint to prevent...
  90. pmc Intakes of fruit, vegetables, and specific botanical groups in relation to lung cancer risk in the NIH-AARP Diet and Health Study
    Margaret E Wright
    Department of Pathology MC 847, College of Medicine, University of Illinois at Chicago, 840 South Wood Street, Room 130, Chicago, IL 60612, USA
    Am J Epidemiol 168:1024-34. 2008
    ..06). These results provide support for a protective role of specific botanical subgroups of fruits and vegetables in lung cancer prevention in men, although the findings could also be due to residual confounding by smoking or chance...
  91. ncbi request reprint Sex steroid hormones and the androgen receptor gene CAG repeat and subsequent risk of prostate cancer in the prostate-specific antigen era
    Elizabeth A Platz
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Room E6138, 615 North Wolfe Street, Baltimore, MD 21205, USA
    Cancer Epidemiol Biomarkers Prev 14:1262-9. 2005
    ..We investigated plasma levels of sex steroid hormones and length of the androgen receptor gene CAG repeat in relation to incident prostate cancer diagnosed in the prostate-specific antigen (PSA) era...
  92. ncbi request reprint Long-term intake of trans-fatty acids and risk of gallstone disease in men
    Chung Jyi Tsai
    Division of Digestive Diseases and Nutrition, University of Kentucky Medical Center, Lexington 40536 0298, USA
    Arch Intern Med 165:1011-5. 2005
    ..The consumption of trans-fatty acids adversely affects blood lipid levels. The relationship with the incidence of gallstone disease is unknown...
  93. ncbi request reprint Obesity and colorectal cancer: epidemiology, mechanisms and candidate genes
    Marc J Gunter
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD 20852, USA
    J Nutr Biochem 17:145-56. 2006
    ..These pathways will be discussed with particular reference to genetic polymorphisms that have been associated with obesity and insulin resistance...
  94. ncbi request reprint Weight cycling and risk of gallstone disease in men
    Chung Jyi Tsai
    Division of Digestive Diseases and Nutrition, University of Kentucky Medical Center, Lexington, KY 40536 0298, USA
    Arch Intern Med 166:2369-74. 2006
    ..The long-term effect of repeated intentional weight loss and weight regain on the risk of gallstone disease in men is not clear...
  95. ncbi request reprint Prospective study of abdominal adiposity and gallstone disease in US men
    Chung Jyi Tsai
    Channing Laboratory, Department of Medicine, Harvard Medical School and Brigham and Women s Hospital, Boston, MA, USA
    Am J Clin Nutr 80:38-44. 2004
    ..Obesity is an established risk factor for gallstones, but whether abdominal adiposity contributes independently to the risk, particularly in men, remains unclear...
  96. ncbi request reprint Serum lycopene, other carotenoids, and prostate cancer risk: a nested case-control study in the prostate, lung, colorectal, and ovarian cancer screening trial
    Ulrike Peters
    Cancer Prevention Program, Fred Hutchinson Cancer Research Center, P O Box 19024, 1100 Fairview Avenue North M4 B402, Seattle, WA 98109 1024, USA
    Cancer Epidemiol Biomarkers Prev 16:962-8. 2007
    ..This has stimulated extensive laboratory and clinical research, as well as much commercial and public enthusiasm. However, the epidemiologic evidence remains inconclusive...
  97. ncbi request reprint Physical activity and renal cell cancer risk in a cohort of male smokers
    Somdat Mahabir
    Cancer Prevention Studies Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA
    Int J Cancer 108:600-5. 2004
    ..18-1.13) (p-value for trend = 0.12). Occupational physical activity was unrelated to renal cell cancer risk. These data suggest that recreational physical activity may play a role in the prevention of renal cell cancer in men...