Kathi A Lefebvre

Summary

Affiliation: National Oceanic and Atmospheric Administration
Country: USA

Publications

  1. pmc Characterization of intracellular and extracellular saxitoxin levels in both field and cultured Alexandrium spp. samples from Sequim Bay, Washington
    Kathi A Lefebvre
    NOAA Fisheries, Northwest Fisheries Science Center, Marine Biotoxins Program, 2725 Montlake Blvd East, Seattle, WA, 98112, USA
    Mar Drugs 6:103-16. 2008
  2. pmc A novel antibody-based biomarker for chronic algal toxin exposure and sub-acute neurotoxicity
    Kathi A Lefebvre
    Exposure Assessment and Biomedical Models, Northwest Fisheries Science Center, National Marine Fisheries Service, NOAA, Seattle, Washington, United States of America
    PLoS ONE 7:e36213. 2012
  3. pmc Centers for Oceans and Human Health: a unified approach to the challenge of harmful algal blooms
    Deana L Erdner
    University of Texas Marine Science Institute, Port Aransas, TX 78373, USA
    Environ Health 7:S2. 2008
  4. ncbi request reprint From sanddabs to blue whales: the pervasiveness of domoic acid
    Kathi A Lefebvre
    Biology Department, University of California at Santa Cruz UCSC, 95064, USA
    Toxicon 40:971-7. 2002
  5. ncbi request reprint Morphological abnormalities and sensorimotor deficits in larval fish exposed to dissolved saxitoxin
    Kathi A Lefebvre
    Environmental Conservation Division, Northwest Fisheries Science Center, National Marine Fisheries Service, National Oceanographic and Atmospheric Administration, 2725 Montlake Blvd E, Seattle, WA 98112, USA
    Aquat Toxicol 66:159-70. 2004
  6. doi request reprint Domoic acid and human exposure risks: a review
    Kathi A Lefebvre
    NOAA Fisheries, Northwest Fisheries Science Center, Marine Biotoxins Program, 2725 Montlake Blvd East, Seattle, WA 98112, United States
    Toxicon 56:218-30. 2010
  7. pmc Gene expression profiles in zebrafish brain after acute exposure to domoic acid at symptomatic and asymptomatic doses
    Kathi A Lefebvre
    Marine Biotoxins Program, National Oceanic and Atmospheric Administration NOAA Fisheries Northwest Fisheries Science Center, 2725 Montlake Boulevard East, Seattle, Washington 98125, USA
    Toxicol Sci 107:65-77. 2009
  8. doi request reprint Comparative determination of paralytic shellfish toxins (PSTs) using five different toxin detection methods in shellfish species collected in the Aleutian Islands, Alaska
    Pedro Reis Costa
    NOAA Fisheries, Northwest Fisheries Science Center, Marine Biotoxins Program, Seattle, WA 98112, USA
    Toxicon 54:313-20. 2009
  9. ncbi request reprint Uptake, tissue distribution and excretion of domoic acid after oral exposure in coho salmon (Oncorhynchus kisutch)
    Kathi A Lefebvre
    NOAA Fisheries, Northwest Fisheries Science Center, Environmental Conservation Division, Marine Biotoxins Program, 2725 Montlake Blvd East, Seattle, WA 98112, USA
    Aquat Toxicol 81:266-74. 2007

Collaborators

Detail Information

Publications9

  1. pmc Characterization of intracellular and extracellular saxitoxin levels in both field and cultured Alexandrium spp. samples from Sequim Bay, Washington
    Kathi A Lefebvre
    NOAA Fisheries, Northwest Fisheries Science Center, Marine Biotoxins Program, 2725 Montlake Blvd East, Seattle, WA, 98112, USA
    Mar Drugs 6:103-16. 2008
    ..7% of the total PSTs present. Collectively, these data confirm that extracellular PSTs are present during blooms of Alexandrium spp. in the Sequim Bay region...
  2. pmc A novel antibody-based biomarker for chronic algal toxin exposure and sub-acute neurotoxicity
    Kathi A Lefebvre
    Exposure Assessment and Biomedical Models, Northwest Fisheries Science Center, National Marine Fisheries Service, NOAA, Seattle, Washington, United States of America
    PLoS ONE 7:e36213. 2012
    ....
  3. pmc Centers for Oceans and Human Health: a unified approach to the challenge of harmful algal blooms
    Deana L Erdner
    University of Texas Marine Science Institute, Port Aransas, TX 78373, USA
    Environ Health 7:S2. 2008
    ....
  4. ncbi request reprint From sanddabs to blue whales: the pervasiveness of domoic acid
    Kathi A Lefebvre
    Biology Department, University of California at Santa Cruz UCSC, 95064, USA
    Toxicon 40:971-7. 2002
    ..Fish as diverse as benthic sanddabs and pelagic albacore were found to contain the neurotoxin, suggesting that DA permeates benthic as well as pelagic communities...
  5. ncbi request reprint Morphological abnormalities and sensorimotor deficits in larval fish exposed to dissolved saxitoxin
    Kathi A Lefebvre
    Environmental Conservation Division, Northwest Fisheries Science Center, National Marine Fisheries Service, National Oceanographic and Atmospheric Administration, 2725 Montlake Blvd E, Seattle, WA 98112, USA
    Aquat Toxicol 66:159-70. 2004
    ..Dissolved algal toxins may therefore have important sublethal effects on vulnerable species of fish...
  6. doi request reprint Domoic acid and human exposure risks: a review
    Kathi A Lefebvre
    NOAA Fisheries, Northwest Fisheries Science Center, Marine Biotoxins Program, 2725 Montlake Blvd East, Seattle, WA 98112, United States
    Toxicon 56:218-30. 2010
    ..The importance of investigating the potential human health impacts of long-term low-level domoic acid exposure in "at risk" human populations is also discussed...
  7. pmc Gene expression profiles in zebrafish brain after acute exposure to domoic acid at symptomatic and asymptomatic doses
    Kathi A Lefebvre
    Marine Biotoxins Program, National Oceanic and Atmospheric Administration NOAA Fisheries Northwest Fisheries Science Center, 2725 Montlake Boulevard East, Seattle, Washington 98125, USA
    Toxicol Sci 107:65-77. 2009
    ..These data provide a basis for identifying pathways of DA-induced injury as well as biomarkers of asymptomatic and symptomatic DA exposure levels...
  8. doi request reprint Comparative determination of paralytic shellfish toxins (PSTs) using five different toxin detection methods in shellfish species collected in the Aleutian Islands, Alaska
    Pedro Reis Costa
    NOAA Fisheries, Northwest Fisheries Science Center, Marine Biotoxins Program, Seattle, WA 98112, USA
    Toxicon 54:313-20. 2009
    ....
  9. ncbi request reprint Uptake, tissue distribution and excretion of domoic acid after oral exposure in coho salmon (Oncorhynchus kisutch)
    Kathi A Lefebvre
    NOAA Fisheries, Northwest Fisheries Science Center, Environmental Conservation Division, Marine Biotoxins Program, 2725 Montlake Blvd East, Seattle, WA 98112, USA
    Aquat Toxicol 81:266-74. 2007
    ..Here, we comprehensively describe the uptake, depuration, and tissue distribution patterns of DA and propose that renal and biliary processes may serve as primary routes of toxin clearance in fish...