Research Topics
| Jennifer Y F LauSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Elucidating risk mechanisms of gene-environment interactions on pediatric anxiety: integrating findings from neuroscienceJennifer Y F Lau
Mood and Anxiety Program, National Institute of Mental Health, NIH, Bethesda, MD 20892, USA
Eur Arch Psychiatry Clin Neurosci 258:97-106. 2008..Exploring these relationships during development is crucial, given that these early life processes may potentially shape longer-term patterns of emotional behavior, and therefore life-long trajectories of anxiety...
Disentangling gene-environment correlations and interactions on adolescent depressive symptomsJennifer Y F Lau
Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, UK
J Child Psychol Psychiatry 49:142-50. 2008..While these effects are often studied independently, evidence supports their co-occurrence on depression...
Fear conditioning in adolescents with anxiety disorders: results from a novel experimental paradigmJennifer Y F Lau
Mood and Anxiety Disorders Program, National Institute of Mental Health National Institutes of Health, 15K North Drive, MSC 2670, Bethesda, MD 20892 2670, USA
J Am Acad Child Adolesc Psychiatry 47:94-102. 2008..Adult data suggest that anxiety disorders involve elevated fear but intact differential conditioning. We used a novel paradigm to assess fear conditioning in pediatric anxiety patients...
Pathways to childhood depressive symptoms: the role of social, cognitive, and genetic risk factorsJennifer Y F Lau
Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, United Kingdom
Dev Psychol 43:1402-14. 2007..Together, these routes accounted for approximately 13% of total phenotypic variance in depressive symptoms. Theoretical and analytical implications of these results are discussed in the context of several design-related caveats...
Assessing gene-environment interactions on anxiety symptom subtypes across childhood and adolescenceJennifer Y F Lau
US National Institute of Mental Health, 15K, North Drive, Bethesda, MD 20892 2670, USA
Dev Psychopathol 19:1129-46. 2007..We interpret these preliminary findings tentatively in the context of gene-environment interaction on anxiety in general, and on early separation and later panic anxiety in particular...
Changes in genetic and environmental influences on depressive symptoms across adolescence and young adulthoodJennifer Y F Lau
Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Health, 15K North Drive, Room 211, Bethesda, MD 20892 2670, USA
Br J Psychiatry 189:422-7. 2006..Depression rises markedly in adolescence, a time when increased and new genetic influences have been reported...
Anxiety-related biases in children's avoidant responses to a masked angry faceJennifer Y F Lau
MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, UK
Behav Res Ther 45:1639-45. 2007..These results suggest a relationship between anxiety and stimulus-response learning for CS+-UCS associations that support behavioural avoidance...
In the face of uncertainty: a twin study of ambiguous information, anxiety and depression in childrenThalia C Eley
Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Kings College London, De Crespigny Park, P O Box P080, London, SE5 8AF, UK
J Abnorm Child Psychol 36:55-65. 2008..The data also support a role for genetic influence on threat interpretations, which may mediate responses to stress...
The direction of longitudinal associations between sleep problems and depression symptoms: a study of twins aged 8 and 10 yearsAlice M Gregory
Department ofPsychology, Goldsmiths College, University ofLondon, London, UK I2lnstitute ofPsychiatry, King s College London, London, UK
Sleep 32:189-99. 2009..To establish the direction and etiology of longitudinal associations between sleep problems and depression symptoms in children...
Does childhood anxiety evoke maternal control? A genetically informed studyThalia C Eley
Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, UK
J Child Psychol Psychiatry 51:772-9. 2010..do not?; 2) to what extent do genetic and environmental factors influence maternal control and child anxiety?; 3) to what extent do genetic and environmental factors influence the associations between child anxiety and maternal control?..
Genetic and environmental influences on interpersonal cognitions and associations with depressive symptoms in 8-year-old twinsAlice M Gregory
Medical Research Council Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, UK
J Abnorm Psychol 116:762-75. 2007..These latter findings may result from interpersonal cognitions in young children, reflecting life experiences as opposed to trait-like cognitive biases...
Amygdala and ventrolateral prefrontal cortex function during anticipated peer evaluation in pediatric social anxietyAmanda E Guyer
Mood and Anxiety Program, National Institute of Mental Health, National Institutes of Health, 15K North Dr, Room 208, Bethesda, MD 20892 2670, USA
Arch Gen Psychiatry 65:1303-12. 2008..Such fear-circuitry dysfunction may also manifest when anticipated social evaluation leads socially anxious adolescents to misperceive peers as threatening...
Attributional style as a risk marker of genetic effects for adolescent depressive symptomsJennifer Y F Lau
Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, UK
J Abnorm Psychol 117:849-59. 2008..Implications for attributional style as a marker reflecting genetic risks are discussed...
The role of children's negative attributions on depressive symptoms: an inherited characteristic or a product of the early environment?Jennifer Y F Lau
Department of Experimental Psychology, University of Oxford, Oxford, UK
Dev Sci 15:569-78. 2012..Placing the present findings with those of adolescents suggests possible developmental differences in the relationship between attributional style and depressive symptoms...
Finding gene-environment interactions for generalised anxiety disorderAlice M Gregory
Psychology Department, Goldsmiths College, University of London, London, UK
Eur Arch Psychiatry Clin Neurosci 258:69-75. 2008....
I think, therefore I am: a twin study of attributional style in adolescentsJennifer Y F Lau
MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, UK
J Child Psychol Psychiatry 47:696-703. 2006..These relationships have mainly been considered in terms of social risk mechanisms, and little is known about the role of genetic influences...
Finding gene-environment interactions for phobiasAlice M Gregory
Psychology Department, Goldsmiths College, University of London, Lewisham Way, New Cross, London, UK
Eur Arch Psychiatry Clin Neurosci 258:76-81. 2008..In addition to the careful conceptualisation of new studies, it is suggested that data already collected should be re-analysed in light of increased understanding of processes influencing phobias...
Gene-environment interactions and correlations in psychiatric disordersJennifer Y F Lau
Social, Genetic, and Developmental Psychiatry Centre, Institute for Psychiatry, DeCrespigny Park, London SE5 8AF, UK
Curr Psychiatry Rep 6:119-24. 2004..These have important implications in guiding future psychiatric research, mental health practice, and policy-making bodies...
Examining the state-trait anxiety relationship: a behavioural genetic approachJennifer Y F Lau
Institute of Psychiatry, King s College London, UK
J Abnorm Child Psychol 34:19-27. 2006..The implications of these results for vulnerability mechanisms involving stress reactivity on anxiety are discussed...
The Genesis 12-19 (G1219) Study: A Twin and Sibling Study of Gene-Environment Interplay and Adolescent Development in the UKTom A McAdams
MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, UK
Twin Res Hum Genet 16:134-43. 2013..In this article, we describe the sample, data collection, and measures used. We also summarize some of the key findings to date...
