Research Topics
| Elaine LanzaSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Inflammation-associated serum and colon markers as indicators of dietary attenuation of colon carcinogenesis in ob/ob miceRoycelynn A Mentor-Marcel
Laboratory of Cancer Prevention, Center for Cancer Research, National Cancer Institute Frederick, 1050 Boyles Street, Frederick, MD 21702, USA
Cancer Prev Res (Phila) 2:60-9. 2009..Changes in a subset of inflammation-associated serum proteins and colon gene expression may serve as response indicators of dietary attenuation of colon carcinogenesis...
Interleukin-6 as a potential indicator for prevention of high-risk adenoma recurrence by dietary flavonols in the polyp prevention trialGerd Bobe
Center for Cancer Research, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland, USA
Cancer Prev Res (Phila) 3:764-75. 2010..Our results suggest that serum IL-6 may serve as a risk indicator and as a response indicator to dietary flavonols for colorectal cancer prevention...
Dietary lignan and proanthocyanidin consumption and colorectal adenoma recurrence in the Polyp Prevention TrialGerd Bobe
Laboratory of Cancer Prevention, Center for Cancer Research, National Cancer Institute NCI, National Institutes of Health NIH, Department of Health and Human Services DHHS, Frederick, MD, USA
Int J Cancer 130:1649-59. 2012..04). To conclude, dietary lignan and proanthocyanidin consumption were not generally related to colorectal adenoma recurrence; however, high lignan intake may increase the risk of adenoma recurrence in women...
Do interleukin polymorphisms play a role in the prevention of colorectal adenoma recurrence by dietary flavonols?Gerd Bobe
Laboratory of Cancer Prevention, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
Eur J Cancer Prev 20:86-95. 2011..In conclusion, our results suggest that IL SNPs, in combination with a flavonol-rich diet or decreased serum IL, may lower the risk of adenoma recurrence...
Dietary cooked navy beans and their fractions attenuate colon carcinogenesis in azoxymethane-induced ob/ob miceGerd Bobe
Laboratory of Cancer Prevention, Center for Cancer Research, National Cancer Institute Frederick, Frederick, Maryland 21702, USA
Nutr Cancer 60:373-81. 2008..04; bean residue 67%, P=0.01; bean extract 87%, P=0.0003. These results suggest that both the soluble and the insoluble fraction of the extract contribute to the cancer-protective effect of cooked navy beans...
Serum adiponectin, leptin, C-peptide, homocysteine, and colorectal adenoma recurrence in the Polyp Prevention TrialGerd Bobe
Laboratory of Cancer Prevention, Center for Cancer Research, National Cancer Institute NCI, NIH, Department of Health and Human Services DHHS, Bethesda, Maryland, USA
Cancer Epidemiol Biomarkers Prev 19:1441-52. 2010..Serum adiponectin, leptin, C-peptide, and homocysteine are indicators for obesity, hyperinsulinemia, and chronic inflammation, which have all been associated with colorectal cancer...
Dietary flavonoids and colorectal adenoma recurrence in the Polyp Prevention TrialGerd Bobe
Laboratory of Cancer Prevention, National Cancer Institute Frederick, Room 110, Building 576, Frederick, MD 21702 1201, USA
Cancer Epidemiol Biomarkers Prev 17:1344-53. 2008..Our data suggest that a flavonol-rich diet may decrease the risk of advanced adenoma recurrence...
Adenomatous polyp recurrence and physical activity in the Polyp Prevention Trial (United States)Lisa H Colbert
National Institute on Aging, Bethesda, MD, USA
Cancer Causes Control 13:445-53. 2002..To examine prospectively the association between physical activity and adenomatous polyp recurrence...
Non-steroidal anti-inflammatory drug use is associated with reduction in recurrence of advanced and non-advanced colorectal adenomas (United States)Joseph A Tangrea
Cancer Prevention Studies Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892 7058, USA
Cancer Causes Control 14:403-11. 2003....
The effect of a low-fat, high fiber, fruit and vegetable intervention on rectal mucosal proliferationRuth Pfeiffer
Division of Cancer Epidemiology and Genetics, National Cancer Institute, The National Institutes of Health, Bethesda, Maryland 20892 7244, USA
Cancer 98:1161-8. 2003..The basic hypothesis underlying these investigations is that specific dietary components may reduce or increase the rate of cell proliferation, which, in turn, may reduce or increase neoplastic changes in the large bowel...
The effect of strict adherence to a high-fiber, high-fruit and -vegetable, and low-fat eating pattern on adenoma recurrenceLeah B Sansbury
Division of Cancer Control and Population Sciences, 6130 Executive Boulevard, Room 5106, Mail Stop Code 7324, Bethesda, MD 20892, USA
Am J Epidemiol 170:576-84. 2009..65, 95% confidence interval: 0.47, 0.92). Findings suggest that high compliance with a low-fat, high-fiber diet is associated with reduced risk of adenoma recurrence...
Gene-specific methylation and subsequent risk of colorectal adenomas among participants of the polyp prevention trialKaren Woodson
Cancer Prevention Studies Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA
Cancer Epidemiol Biomarkers Prev 14:1219-23. 2005..No association between CDKN2A, PTGS2, or PGR methylation and adenoma recurrence was observed. These data suggest that ESR1 methylation may play a role in subsequent adenoma recurrence...
Utilization and yield of surveillance colonoscopy in the continued follow-up study of the polyp prevention trialAdeyinka O Laiyemo
Cancer Prevention Fellowship Program, Office of Preventive Oncology, National Cancer Institute, Bethesda, Maryland 20892, USA
Clin Gastroenterol Hepatol 7:562-7; quiz 497. 2009..We examined the use and yield of surveillance colonoscopy among participants in the Polyp Prevention Trial (PPT) after the 4-year dietary intervention trial ended...
Dopamine D2 receptor polymorphisms and adenoma recurrence in the Polyp Prevention TrialGwen Murphy
Cancer Prevention Fellowship Program, Office of Preventive Oncology, National Cancer Institute, Bethesda, MD 20892, USA
Int J Cancer 124:2148-51. 2009..Increased risk of adenoma recurrence as conferred by DRD2 genotypes may be related to difference in alcohol and fat intake across genotypes...
Hyperplastic polyps and the risk of adenoma recurrence in the polyp prevention trialAdeyinka O Laiyemo
Cancer Prevention Fellowship Program, Office of Preventive Oncology, National Cancer Institute, Bethesda, Maryland 20892, USA
Clin Gastroenterol Hepatol 7:192-7. 2009..Prospective information on the risk of adenoma recurrence associated with hyperplastic polyps is limited. We sought to investigate whether the coexistence of hyperplastic polyps with adenomas increases the risk of adenoma recurrence...
No association between fatty acid intake and adenomatous polyp recurrence in the polyp prevention trialMarie M Cantwell
Center Cancer Research, National Cancer Institute, NIH, 6116 Executive Boulevard, Suite 702, Room 7218, Bethesda, MD 20892, USA
Cancer Epidemiol Biomarkers Prev 14:2059-60. 2005
Polynucleotide kinase 3' phosphatase variant, dietary variables and risk of adenoma recurrence in the Polyp Prevention TrialGwen Murphy
Cancer Prevention Fellowship Program, Office of Preventive Oncology, Bethesda, Maryland, USA
Eur J Cancer Prev 17:287-90. 2008..Furthermore, we found no effect modification between genotype, dietary components and risk of adenoma recurrence. The PNKP T5644G variant does not seem to be involved in adenoma recurrence in the Polyp Prevention Trial...
Postpolypectomy colonoscopy surveillance guidelines: predictive accuracy for advanced adenoma at 4 yearsAdeyinka O Laiyemo
Cancer Prevention Fellowship Program, Biometry Research Group, Divisionof Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
Ann Intern Med 148:419-26. 2008..Lack of confidence in postpolypectomy surveillance guidelines may be a factor in the observed low adherence rates among providers...
Folate and MTHFR: risk of adenoma recurrence in the Polyp Prevention TrialGwen Murphy
Cancer Prevention Fellowship Program, Office of Preventive Oncology, Bethesda, MD, USA
Cancer Causes Control 19:751-8. 2008..A C/T transition at position 677 in the gene encoding methlylenetetrahydrofolate reductase (MTHFR C677T) has been reported to interact with folate intake to modulate colorectal adenoma recurrence or cancer risk...
Adherence to the polyp prevention trial dietary intervention is associated with a behavioral pattern of adherence to nondietary trial requirements and general health recommendationsKay L Wanke
Epidemiology Research Branch, Division of Epidemiology, Services and Prevention Research, National Institute on Drug Abuse, Bethesda, MD 20892, USA
J Nutr 137:391-8. 2007..These individuals also were more likely to adhere to social norms for healthy lifestyles and demonstrated greater adherence to other aspects of trial participation...
High dry bean intake and reduced risk of advanced colorectal adenoma recurrence among participants in the polyp prevention trialElaine Lanza
Nutritional Epidemiology Branch, Division of Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
J Nutr 136:1896-903. 2006..001). The median in the highest quartile of change in dry bean intake was 370% higher than the baseline intake. The PPT trial-based cohort provides evidence that dry beans may be inversely associated with advanced adenoma recurrence...
Inflammatory cytokine gene polymorphisms, nonsteroidal anti-inflammatory drug use, and risk of adenoma polyp recurrence in the polyp prevention trialLeah B Sansbury
Center for Cancer Research, National Cancer Institute, NIH, Department of Health and Human Services, Suite 702, 6116 Executive Boulevard, MSC 8235, Bethesda, MD 20892 8325, USA
Cancer Epidemiol Biomarkers Prev 15:494-501. 2006..Furthermore, common variants in cytokine genes may modify the anti-inflammatory effect of nonsteroidal anti-inflammatory drugs (NSAIDs) in the prevention of colorectal cancer...
