Charles E Land

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Cancer risks attributable to low doses of ionizing radiation: assessing what we really know
    David J Brenner
    Center for Radiological Research, Columbia University, 630 West 168th Street, New York, NY 10032, USA
    Proc Natl Acad Sci U S A 100:13761-6. 2003
  2. ncbi request reprint Incidence of female breast cancer among atomic bomb survivors, Hiroshima and Nagasaki, 1950-1990
    Charles E Land
    Radiation Epidemiology Branch, National Cancer Institute, Bethesda, Maryland, USA
    Radiat Res 160:707-17. 2003
  3. pmc Projected lifetime cancer risks from exposure to regional radioactive fallout in the Marshall Islands
    Charles E Land
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Boulevard, Bethesda, MD 20892, USA
    Health Phys 99:201-15. 2010
  4. pmc Radiation doses and cancer risks in the Marshall Islands associated with exposure to radioactive fallout from Bikini and Enewetak nuclear weapons tests: summary
    Steven L Simon
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Boulevard, Bethesda, MD 20892, USA
    Health Phys 99:105-23. 2010
  5. pmc Thyroid nodules, polymorphic variants in DNA repair and RET-related genes, and interaction with ionizing radiation exposure from nuclear tests in Kazakhstan
    Alice J Sigurdson
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD 20892 7238, USA
    Radiat Res 171:77-88. 2009
  6. ncbi request reprint Thyroid cancer in childhood cancer survivors: a detailed evaluation of radiation dose response and its modifiers
    Cécile M Ronckers
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, Maryland
    Radiat Res 166:618-28. 2006
  7. pmc Cancer mortality among women frequently exposed to radiographic examinations for spinal disorders
    Cécile M Ronckers
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland 20852, USA
    Radiat Res 174:83-90. 2010
  8. ncbi request reprint Coronary heart disease after radiotherapy for peptic ulcer disease
    Zhanat A Carr
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH DHHS, 6120 Executive Boulevard, EPS 7038, Rockville, MD 20852, USA
    Int J Radiat Oncol Biol Phys 61:842-50. 2005
  9. doi request reprint Multiple diagnostic X-rays for spine deformities and risk of breast cancer
    Cécile M Ronckers
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, EPS 7046, 6120 Executive Boulevard, MS 7238, Bethesda, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 17:605-13. 2008
  10. ncbi request reprint Low-dose extrapolation of radiation health risks: some implications of uncertainty for radiation protection at low doses
    Charles E Land
    National Cancer Institute National Institutes of Health, Radiation Epidemiology Branch EPS 7046, 6120 Executive Boulevard, MS7238, Bethesda, MD 20892 7238, USA
    Health Phys 97:407-15. 2009

Detail Information

Publications25

  1. pmc Cancer risks attributable to low doses of ionizing radiation: assessing what we really know
    David J Brenner
    Center for Radiological Research, Columbia University, 630 West 168th Street, New York, NY 10032, USA
    Proc Natl Acad Sci U S A 100:13761-6. 2003
    ..This linearity assumption is not necessarily the most conservative approach, and it is likely that it will result in an underestimate of some radiation-induced cancer risks and an overestimate of others...
  2. ncbi request reprint Incidence of female breast cancer among atomic bomb survivors, Hiroshima and Nagasaki, 1950-1990
    Charles E Land
    Radiation Epidemiology Branch, National Cancer Institute, Bethesda, Maryland, USA
    Radiat Res 160:707-17. 2003
    ..ERR(1Sv) was observed to decline with increasing attained age, with by far the largest drop around age 35. Possible explanations for these observations are discussed, along with research approaches that might provide more information...
  3. pmc Projected lifetime cancer risks from exposure to regional radioactive fallout in the Marshall Islands
    Charles E Land
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Boulevard, Bethesda, MD 20892, USA
    Health Phys 99:201-15. 2010
    ....
  4. pmc Radiation doses and cancer risks in the Marshall Islands associated with exposure to radioactive fallout from Bikini and Enewetak nuclear weapons tests: summary
    Steven L Simon
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Boulevard, Bethesda, MD 20892, USA
    Health Phys 99:105-23. 2010
    ..The 170 excess cancers are in comparison to about 10,600 cancers that would spontaneously arise, unrelated to radioactive fallout, among the same cohort of Marshallese people...
  5. pmc Thyroid nodules, polymorphic variants in DNA repair and RET-related genes, and interaction with ionizing radiation exposure from nuclear tests in Kazakhstan
    Alice J Sigurdson
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD 20892 7238, USA
    Radiat Res 171:77-88. 2009
    ..Other pathways such as genes in double-strand break repair, apoptosis and genes related to proliferation should also be pursued...
  6. ncbi request reprint Thyroid cancer in childhood cancer survivors: a detailed evaluation of radiation dose response and its modifiers
    Cécile M Ronckers
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, Maryland
    Radiat Res 166:618-28. 2006
    ..In summary, we applied models derived from radiobiology to describe the radiation dose-response curve for thyroid cancer in an epidemiological study and found convincing evidence for a downturn in risk at high doses...
  7. pmc Cancer mortality among women frequently exposed to radiographic examinations for spinal disorders
    Cécile M Ronckers
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland 20852, USA
    Radiat Res 174:83-90. 2010
    ..77), cervical (SMR = 0.31), and liver (SMR = 0.17). The excess relative risk (ERR) for breast cancer mortality increased significantly with 10-year lagged radiation dose to the breast (ERR/Gy = 3.9; 95% CI: 1.0-9.3)...
  8. ncbi request reprint Coronary heart disease after radiotherapy for peptic ulcer disease
    Zhanat A Carr
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH DHHS, 6120 Executive Boulevard, EPS 7038, Rockville, MD 20852, USA
    Int J Radiat Oncol Biol Phys 61:842-50. 2005
    ..To evaluate the risk of coronary heart disease (CHD) and cerebrovascular disease after radiotherapy (RT) for peptic ulcer disease...
  9. doi request reprint Multiple diagnostic X-rays for spine deformities and risk of breast cancer
    Cécile M Ronckers
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, EPS 7046, 6120 Executive Boulevard, MS 7238, Bethesda, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 17:605-13. 2008
    ..In this historic cohort, 95% of daily dose increments (when exposure to the breast occurred) were under 2.4 cGy, with mean 1.1 cGy...
  10. ncbi request reprint Low-dose extrapolation of radiation health risks: some implications of uncertainty for radiation protection at low doses
    Charles E Land
    National Cancer Institute National Institutes of Health, Radiation Epidemiology Branch EPS 7046, 6120 Executive Boulevard, MS7238, Bethesda, MD 20892 7238, USA
    Health Phys 97:407-15. 2009
    ....
  11. pmc Radiation and breast cancer: a review of current evidence
    Cécile M Ronckers
    National Cancer Institute, Division of Cancer Epidemiology and Genetics, NIH, HHS, Bethesda, Maryland, USA
    Breast Cancer Res 7:21-32. 2005
    ....
  12. ncbi request reprint Late health effects of childhood nasopharyngeal radium irradiation: nonmelanoma skin cancers, benign tumors, and hormonal disorders
    Cécile M Ronckers
    Department of Ear, Nose and Throat Medicine, Reinaert Kliniek, Maastricht, The Netherlands
    Pediatr Res 52:850-8. 2002
    ..0-2.1). We found no evidence of highly elevated risk of benign head and neck tumors, nonmelanoma skin cancer, thyroid disorders, or indicators of pituitary radiation damage after childhood NRI in The Netherlands...
  13. ncbi request reprint Cancer incidence after nasopharyngeal radium irradiation
    Cécile M Ronckers
    Department of Ear Nose and Throat Medicine, Reinaert Kliniek, Maastricht, The Netherlands
    Epidemiology 13:552-60. 2002
    ..From 1940 until 1970, nasopharyngeal radium irradiation was used to treat children and military personnel suffering from Eustachian tube failure attributable to local lymphoid hyperplasia...
  14. ncbi request reprint Health effects from fallout
    Ethel S Gilbert
    Division of Cancer Epidemiotogy and Genetics, National Cancer Institute, NIH, Rockville, MD 20852, USA
    Health Phys 82:726-35. 2002
    ..Very preliminary estimates of cancer risks from fallout doses received by the United States population are presented...
  15. ncbi request reprint Site-specific cancer incidence and mortality after cerebral angiography with radioactive thorotrast
    Lois B Travis
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, Maryland 20892, USA
    Radiat Res 160:691-706. 2003
    ..Nonetheless, the substantial risks associated with liver cancer and leukemia indicate that unique and prolonged exposure to alpha-particle-emitting Thorotrast increased carcinogenic risks...
  16. pmc Behavior and food consumption pattern of the population exposed in 1949-1962 to fallout from Semipalatinsk nuclear test site in Kazakhstan
    Vladimir Drozdovitch
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, 6120 Executive Boulevard, Bethesda, MD, 20892 7238, USA
    Radiat Environ Biophys 50:91-103. 2011
    ..The response data collected are useful for improving estimates of thyroid radiation dose estimates for the subjects of an ongoing epidemiological study...
  17. ncbi request reprint External dose estimates for Dolon village: application of the U.S./Russian joint methodology
    Steven L Simon
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    J Radiat Res 47:A143-7. 2006
    ..This report presents the basic elements of the joint methodology model for estimation of external dose received from SNTS fallout...
  18. pmc Incidence of carcinoma of the major salivary glands according to the WHO classification, 1992 to 2006: a population-based study in the United States
    Houda Boukheris
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute NIH, Bethesda, Maryland, USA
    Cancer Epidemiol Biomarkers Prev 18:2899-906. 2009
    ..Carcinomas of the major salivary glands (M-SGC) comprise a morphologically diverse group of rare tumors of largely unknown cause. To gain insight into etiology, we evaluated incidence of M-SGC using the WHO classification schema (WHO-2005)...
  19. ncbi request reprint Uncertainty, low-dose extrapolation and the threshold hypothesis
    Charles E Land
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
    J Radiol Prot 22:A129-35. 2002
    ..Allowing for the possibility of a threshold would, however, remove very little of the regulatory burden associated with the so-called linear, no-threshold hypothesis, unless that possibility were a virtual certainty...
  20. ncbi request reprint Malignant neoplasms after radiation therapy for peptic ulcer
    Zhanat A Carr
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
    Radiat Res 157:668-77. 2002
    ..Our excess relative risk per gray estimate of 0.20 at doses <or=10 Gy (95% CI 0, 0.73) is consistent with the estimate of 0.24 (95% CI 0.10, 0.40) obtained from the LSS study with the linear model...
  21. ncbi request reprint Breast cancer
    Cécile M Ronckers
    Lancet 366:1605-6; author reply 1606. 2005
  22. pmc Interactive RadioEpidemiological Program (IREP): a web-based tool for estimating probability of causation/assigned share of radiogenic cancers
    David C Kocher
    SENES Oak Ridge, Inc, 102 Donner Drive, Oak Ridge, TN 37830, USA
    Health Phys 95:119-47. 2008
    ....
  23. ncbi request reprint Improving the efficiency of nested case-control studies of interaction by selecting controls using counter matching on exposure
    John B Cologne
    Departments of Radiobiology Molecular Epidemiology, Radiation Effects Research Foundation, Hiroshima, Japan
    Int J Epidemiol 33:485-92. 2004
    ....
  24. ncbi request reprint Heterozygous individuals bearing a founder mutation in the XPA DNA repair gene comprise nearly 1% of the Japanese population
    Yuko Hirai
    Department of Genetics, Radiation Effects Research Foundation, 5 2 Hijiyama Park, Hiroshima, Japan
    Mutat Res 601:171-8. 2006
    ..88%. This rate, if representative, implies that there are about 1 million carriers of the XPA founder mutation in the Japanese population. Thus, investigation of their cancer risk may be warranted...
  25. ncbi request reprint A pathology study of malignant and benign ovarian tumors among atomic-bomb survivors--case series report
    Kouki Inai
    Department of Pathology, Division of Medical Intelligence and Informatics, Graduate School of Biomedical Sciences, Hiroshima University, Japan
    J Radiat Res 47:49-59. 2006
    ..Variations in histological types of ovarian tumors in response to radiation dose, suggested by the case series data need to be followed up by population-based incidence analysis...