Thomas M Kristie

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Control of alpha-herpesvirus IE gene expression by HCF-1 coupled chromatin modification activities
    Thomas M Kristie
    Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 4 129, 4 Center Drive, Bethesda, Maryland 20892, USA
    Biochim Biophys Acta 1799:257-65. 2010
  2. ncbi request reprint The mouse homologue of the human transcription factor C1 (host cell factor). Conservation of forms and function
    T M Kristie
    Laboratory of Viral Diseases, NIAID, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Biol Chem 272:26749-55. 1997
  3. pmc Nuclear localization of the C1 factor (host cell factor) in sensory neurons correlates with reactivation of herpes simplex virus from latency
    T M Kristie
    Laboratory of Viral Diseases, National Institutes of Health, Building 4 133, 9000, Rockville Pike, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 96:1229-33. 1999
  4. pmc The coactivator host cell factor-1 mediates Set1 and MLL1 H3K4 trimethylation at herpesvirus immediate early promoters for initiation of infection
    Aarthi Narayanan
    Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Building 4 131, 4 Center Drive, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 104:10835-40. 2007
  5. pmc Inhibition of the histone demethylase LSD1 blocks alpha-herpesvirus lytic replication and reactivation from latency
    Yu Liang
    Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, US National Institutes of Health, Bethesda, MD, USA
    Nat Med 15:1312-7. 2009
  6. pmc Transcriptional coactivator HCF-1 couples the histone chaperone Asf1b to HSV-1 DNA replication components
    Hua Peng
    Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bld 4 131, 4 Center Drive, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 107:2461-6. 2010
  7. ncbi request reprint Combinatorial transcription of herpes simplex virus and varicella zoster virus immediate early genes is strictly determined by the cellular coactivator HCF-1
    Aarthi Narayanan
    Laboratory of Viral Diseases, NIAID, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Biol Chem 280:1369-75. 2005
  8. pmc Site-specific proteolysis of the transcriptional coactivator HCF-1 can regulate its interaction with protein cofactors
    Jodi L Vogel
    Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Building 4 131, 4 Center Drive, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 103:6817-22. 2006
  9. doi request reprint Targeting the JMJD2 histone demethylases to epigenetically control herpesvirus infection and reactivation from latency
    Yu Liang
    Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Sci Transl Med 5:167ra5. 2013
  10. pmc A novel selective LSD1/KDM1A inhibitor epigenetically blocks herpes simplex virus lytic replication and reactivation from latency
    Yu Liang
    Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
    MBio 4:e00558-12. 2013

Collaborators

Detail Information

Publications18

  1. pmc Control of alpha-herpesvirus IE gene expression by HCF-1 coupled chromatin modification activities
    Thomas M Kristie
    Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 4 129, 4 Center Drive, Bethesda, Maryland 20892, USA
    Biochim Biophys Acta 1799:257-65. 2010
    ..Strikingly, the absence of HCF-1 results in the accumulation of nucleosomes bearing repressive marks on the viral IE promoters and silencing of viral gene expression...
  2. ncbi request reprint The mouse homologue of the human transcription factor C1 (host cell factor). Conservation of forms and function
    T M Kristie
    Laboratory of Viral Diseases, NIAID, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Biol Chem 272:26749-55. 1997
    ..Interestingly, the differential expression of the C1 factors in both human and mouse tissues may be important for the determination of HSV tissue tropism in these two organisms...
  3. pmc Nuclear localization of the C1 factor (host cell factor) in sensory neurons correlates with reactivation of herpes simplex virus from latency
    T M Kristie
    Laboratory of Viral Diseases, National Institutes of Health, Building 4 133, 9000, Rockville Pike, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 96:1229-33. 1999
    ..The regulated localization suggests that C1 is a critical switch determinant of the viral lytic-latent cycle...
  4. pmc The coactivator host cell factor-1 mediates Set1 and MLL1 H3K4 trimethylation at herpesvirus immediate early promoters for initiation of infection
    Aarthi Narayanan
    Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Building 4 131, 4 Center Drive, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 104:10835-40. 2007
    ..These studies also contribute to the model whereby the induced nuclear transport of HCF-1 in sensory neurons may be critical to the reactivation of latent herpesviruses by promoting the activation of chromatin modifications...
  5. pmc Inhibition of the histone demethylase LSD1 blocks alpha-herpesvirus lytic replication and reactivation from latency
    Yu Liang
    Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, US National Institutes of Health, Bethesda, MD, USA
    Nat Med 15:1312-7. 2009
    ..The results support pharmaceutical control of histone modifying enzymes as a strategy for controlling herpesvirus infections...
  6. pmc Transcriptional coactivator HCF-1 couples the histone chaperone Asf1b to HSV-1 DNA replication components
    Hua Peng
    Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bld 4 131, 4 Center Drive, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 107:2461-6. 2010
    ..This coupling provides a novel function for HCF-1 and insights into the mechanisms of modulating chromatin during DNA replication...
  7. ncbi request reprint Combinatorial transcription of herpes simplex virus and varicella zoster virus immediate early genes is strictly determined by the cellular coactivator HCF-1
    Aarthi Narayanan
    Laboratory of Viral Diseases, NIAID, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Biol Chem 280:1369-75. 2005
    ..The requirements for this protein supports the model whereby the regulated transport of HCF-1 from the cytoplasm to the nucleus in sensory neurons may control IE gene expression and reactivation of these viruses from the latent state...
  8. pmc Site-specific proteolysis of the transcriptional coactivator HCF-1 can regulate its interaction with protein cofactors
    Jodi L Vogel
    Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Building 4 131, 4 Center Drive, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 103:6817-22. 2006
    ..This paradigm expands the biological significance of limited proteolytic processing as a regulatory mechanism in gene transcription...
  9. doi request reprint Targeting the JMJD2 histone demethylases to epigenetically control herpesvirus infection and reactivation from latency
    Yu Liang
    Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Sci Transl Med 5:167ra5. 2013
    ....
  10. pmc A novel selective LSD1/KDM1A inhibitor epigenetically blocks herpes simplex virus lytic replication and reactivation from latency
    Yu Liang
    Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
    MBio 4:e00558-12. 2013
    ....
  11. pmc Association of the cellular coactivator HCF-1 with the Golgi apparatus in sensory neurons
    Gaelle Kolb
    National Institutes of Health, 4 129, 4 Center Drive, Bethesda, MD 20892, USA
    J Virol 82:9555-63. 2008
    ..The results support the model that HCF-1 is an important component of the viral latency-reactivation cycle and that it is regulated by association with a component that is distinct from the identified HCF-1 interaction factors...
  12. ncbi request reprint The cellular C1 factor of the herpes simplex virus enhancer complex is a family of polypeptides
    T M Kristie
    Laboratory of Viral Diseases, National Institutes of Health, Bethesda, Maryland 20892
    J Biol Chem 270:4387-94. 1995
    ..Although the C1 factor appears to be ubiquitously expressed, it is localized to subnuclear structures in specific cell types...
  13. pmc Recruitment of the transcriptional coactivator HCF-1 to viral immediate-early promoters during initiation of reactivation from latency of herpes simplex virus type 1
    Zackary Whitlow
    Molecular Genetics Section, Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Virol 83:9591-5. 2009
    ..The data support the model whereby HCF-1 plays a pivotal role in the reactivation of HSV-1 from latency...
  14. ncbi request reprint A protein sequestering system reveals control of cellular programs by the transcriptional coactivator HCF-1
    Bharat Khurana
    Laboratory of Viral Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Biol Chem 279:33673-83. 2004
    ..Additionally, cellular transcriptional events were identified that contribute to understanding the functions ascribed to the protein and implicate the protein in events that impact the regulation of critical cellular processes...
  15. pmc Herpes simplex virus infections are arrested in Oct-1-deficient cells
    Mauricio L Nogueira
    Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Building 4 131, 4 Center Drive, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 101:1473-8. 2004
    ..The results have implications for both the HSV lytic and latency-reactivation cycles...
  16. pmc The novel coactivator C1 (HCF) coordinates multiprotein enhancer formation and mediates transcription activation by GABP
    J L Vogel
    Laboratory of Viral Diseases, National Institutes of Health, Building 4, Room 133, 4 Center Drive, Bethesda, MD 20892, USA
    EMBO J 19:683-90. 2000
    ..The interaction and coordinated assembly of the enhancer proteins by the C1 factor may be critical for the regulation of the HSV lytic-latent cycle...
  17. pmc The dynamics of HCF-1 modulation of herpes simplex virus chromatin during initiation of infection
    Jodi L Vogel
    National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bld 33, 33 North Drive, Bethesda, MD 20892, USA
    Viruses 5:1272-91. 2013
    ....
  18. ncbi request reprint Purification of the cellular C1 factor required for the stable recognition of the Oct-1 homeodomain by the herpes simplex virus alpha-trans-induction factor (VP16)
    T M Kristie
    Center for Cancer Research, Massachusetts Institute of Technology, Cambridge 02139
    J Biol Chem 268:6525-34. 1993
    ....