J Krakoff

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi Bimodal distribution of RNA expression levels in human skeletal muscle tissue
    Clinton C Mason
    Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, 1550 E, Indian School Rd, Phoenix, AZ 85014, USA
    BMC Genomics 12:98. 2011
  2. ncbi Comparison of the effect of plasma glucose concentrations on microvascular disease between Pima Indian youths and adults
    J Krakoff
    National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, 1550 E Indian School Road, Phoenix, AZ 85014, USA
    Diabetes Care 24:1023-8. 2001
  3. ncbi Use of a parenteral propylene glycol-containing etomidate preparation for the long-term management of ectopic Cushing's syndrome
    J Krakoff
    National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona 85014, USA
    J Clin Endocrinol Metab 86:4104-8. 2001
  4. ncbi Lower metabolic rate in individuals heterozygous for either a frameshift or a functional missense MC4R variant
    Jonathan Krakoff
    Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Disease, Phoenix, AZ, USA
    Diabetes 57:3267-72. 2008
  5. ncbi Incidence of retinopathy and nephropathy in youth-onset compared with adult-onset type 2 diabetes
    Jonathan Krakoff
    National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona 85014, USA
    Diabetes Care 26:76-81. 2003
  6. ncbi Inflammatory markers, adiponectin, and risk of type 2 diabetes in the Pima Indian
    Jonathan Krakoff
    Diabetes and Arthritis Epidemiology Section, Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona 85014, USA
    Diabetes Care 26:1745-51. 2003
  7. ncbi Gamma globulin levels predict type 2 diabetes in the Pima Indian population
    R S Lindsay
    National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 1550 East Indian School Rd, Phoenix, AZ 85014, USA
    Diabetes 50:1598-603. 2001
  8. ncbi The 24-h carbohydrate oxidation rate in a human respiratory chamber predicts ad libitum food intake
    Nicola Pannacciulli
    Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Phoenix, AZ, USA
    Am J Clin Nutr 86:625-32. 2007
  9. ncbi Higher incremental insulin area under the curve during oral glucose tolerance test predicts less food intake and weight gain
    J He
    Department of Health and Human Services, Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, AZ 85016, USA
    Int J Obes (Lond) 35:1495-501. 2011
  10. ncbi The effect of salsalate on insulin action and glucose tolerance in obese non-diabetic patients: results of a randomised double-blind placebo-controlled study
    J Koska
    Obesity and Diabetes Clinical Research Section, NIDDK NIH DHHS, 4212 N 16th Street, Phoenix, AZ, USA
    Diabetologia 52:385-93. 2009

Detail Information

Publications56

  1. ncbi Bimodal distribution of RNA expression levels in human skeletal muscle tissue
    Clinton C Mason
    Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, 1550 E, Indian School Rd, Phoenix, AZ 85014, USA
    BMC Genomics 12:98. 2011
    ....
  2. ncbi Comparison of the effect of plasma glucose concentrations on microvascular disease between Pima Indian youths and adults
    J Krakoff
    National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, 1550 E Indian School Road, Phoenix, AZ 85014, USA
    Diabetes Care 24:1023-8. 2001
    ..To examine whether the current adult guidelines for diagnosis of diabetes are applicable to youth (age <20 years)...
  3. ncbi Use of a parenteral propylene glycol-containing etomidate preparation for the long-term management of ectopic Cushing's syndrome
    J Krakoff
    National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona 85014, USA
    J Clin Endocrinol Metab 86:4104-8. 2001
    ..Parenteral propylene glycol containing etomidate can be used safely for a prolonged period to reduce hypercortisolemia in patients unable to take oral medications...
  4. ncbi Lower metabolic rate in individuals heterozygous for either a frameshift or a functional missense MC4R variant
    Jonathan Krakoff
    Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Disease, Phoenix, AZ, USA
    Diabetes 57:3267-72. 2008
    ..Humans with functional variants in the melanocortin 4 receptor (MC4R) are obese, hyperphagic, and hyperinsulinemic but have been reported to have no difference in energy expenditure...
  5. ncbi Incidence of retinopathy and nephropathy in youth-onset compared with adult-onset type 2 diabetes
    Jonathan Krakoff
    National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona 85014, USA
    Diabetes Care 26:76-81. 2003
    ..To examine the risk of retinopathy and nephropathy in participants in whom type 2 diabetes was diagnosed in youth (before 20 years of age) compared with those in whom type 2 diabetes was diagnosed at older ages...
  6. ncbi Inflammatory markers, adiponectin, and risk of type 2 diabetes in the Pima Indian
    Jonathan Krakoff
    Diabetes and Arthritis Epidemiology Section, Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona 85014, USA
    Diabetes Care 26:1745-51. 2003
    ....
  7. ncbi Gamma globulin levels predict type 2 diabetes in the Pima Indian population
    R S Lindsay
    National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 1550 East Indian School Rd, Phoenix, AZ 85014, USA
    Diabetes 50:1598-603. 2001
    ..04 [0.90-1.20]; P = 0.6). Thus, gamma globulin levels predict increased risk of diabetes in the Pima population. We suggest that immune function or activation may play a role in the development of type 2 diabetes...
  8. ncbi The 24-h carbohydrate oxidation rate in a human respiratory chamber predicts ad libitum food intake
    Nicola Pannacciulli
    Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Phoenix, AZ, USA
    Am J Clin Nutr 86:625-32. 2007
    ..The 24-h respiratory quotient (24-h RQ) and 24-h carbohydrate balance (24-h CHO-Bal) are predictors of weight change. Whether these relations are mediated by the effects of substrate oxidation and balance on food intake is not known...
  9. ncbi Higher incremental insulin area under the curve during oral glucose tolerance test predicts less food intake and weight gain
    J He
    Department of Health and Human Services, Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, AZ 85016, USA
    Int J Obes (Lond) 35:1495-501. 2011
    ..To investigate the correlation of peripheral insulin concentrations with food intake and body weight...
  10. ncbi The effect of salsalate on insulin action and glucose tolerance in obese non-diabetic patients: results of a randomised double-blind placebo-controlled study
    J Koska
    Obesity and Diabetes Clinical Research Section, NIDDK NIH DHHS, 4212 N 16th Street, Phoenix, AZ, USA
    Diabetologia 52:385-93. 2009
    ..The present study evaluated whether treatment with salsalate, a traditional anti-inflammatory medication, would improve insulin action in obese non-diabetic individuals...
  11. ncbi Reanalysis of the obesity-related attenuation in the left dorsolateral prefrontal cortex response to a satiating meal using gyral regions-of-interest
    Duc Son Nguyen Trung Le
    Obesity and Diabetes Clinical Research Section, NIDDK NIH, DHHS, Phoenix, Arizona 85016, USA
    J Am Coll Nutr 28:667-73. 2009
    ..In this study, we sought to determine which gyri in the LDLPFC best distinguished the neuronal responses to a meal using a different statistical approach...
  12. ncbi Distribution of subcutaneous fat predicts insulin action in obesity in sex-specific manner
    Juraj Koska
    Obesity and Diabetes Clinical Research Section, NIDDK NIH DHHS, Phoenix, Arizona, USA
    Obesity (Silver Spring) 16:2003-9. 2008
    ....
  13. ncbi Childhood predictors of young-onset type 2 diabetes
    Paul W Franks
    Diabetes Epidemiology and Clinical Research Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 1550 E Indian School Rd, Phoenix, AZ 85014, USA
    Diabetes 56:2964-72. 2007
    ..Optimal prevention of young-onset type 2 diabetes requires identification of the early-life modifiable risk factors. We aimed to do this using longitudinal data in 1,604 5- to 19-year-old initially nondiabetic American Indians...
  14. ncbi Repeatability and reproducibility of the hyperinsulinemic-euglycemic clamp and the tracer dilution technique in a controlled inpatient setting
    Duc Son N T Le
    Obesity and Diabetes Clinical Research Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, AZ 85016, USA
    Metabolism 58:304-10. 2009
    ..Decreased glucose infusion rate and M over a short period in the second clamp may reflect an accumulative effect of continued physical inactivity...
  15. ncbi Glycemic control in youth with diabetes: the SEARCH for diabetes in Youth Study
    Diana B Petitti
    Biomedical Informatics, Arizona State University, Phoenix, AZ, USA
    J Pediatr 155:668-72.e1-3. 2009
    ..To assess correlates of glycemic control in a diverse population of children and youth with diabetes...
  16. ncbi Free triiodothyronine plasma concentrations are positively associated with insulin secretion in euthyroid individuals
    Emilio Ortega
    Obesity and Diabetes Clinical Research Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 4212 North 16th Street, Room 5 35, Phoenix, Arizona 85016, USA
    Eur J Endocrinol 158:217-21. 2008
    ..Thyroid hormones (TH) may influence glucose metabolism. Hyperthyroid subjects have higher insulin secretion rates when compared with euthyroid individuals...
  17. ncbi The association of plasma fibrinogen concentration with diabetic microvascular complications in young adults with early-onset of type 2 diabetes
    Duc Son N T Le
    Obesity and Diabetes Clinical Research Section, NIDDK NIH, DHHS, 4212 N 16th Street, Room 5 35, Phoenix, AZ, USA
    Diabetes Res Clin Pract 82:317-23. 2008
    ..We investigated the associations of the markers with microvascular complications in Pima Indians (PI) with early-onset type 2 diabetes (T2DM)...
  18. ncbi Increasing incidence of proteinuria and declining incidence of end-stage renal disease in diabetic Pima Indians
    M E Pavkov
    Diabetes Epidemiology and Clinical Research Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona, USA
    Kidney Int 70:1840-6. 2006
    ..On the other hand, the incidence of ESRD declined after 1990, coinciding with improved control of blood pressure, hyperglycemia, and perhaps other risk factors...
  19. ncbi Circulating white blood cell count and measures of adipose tissue inflammation predict higher 24-h energy expenditure
    Jianying He
    Department of Health and Human Services, Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona 85016, USA
    Eur J Endocrinol 162:275-80. 2010
    ..However, whether subclinical inflammation has a role in increasing EE, which may be at the cost of developing insulin resistance, is not clear...
  20. ncbi Maternal influence, not diabetic intrauterine environment, predicts children's energy intake
    Marci E Gluck
    Obesity and Diabetes Clinical Research Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona, USA
    Obesity (Silver Spring) 17:772-7. 2009
    ..These findings indicate that in this subset of children in a controlled in-patient setting, maternal influence may outweigh intrauterine effects on energy intake...
  21. ncbi Macrophage content in subcutaneous adipose tissue: associations with adiposity, age, inflammatory markers, and whole-body insulin action in healthy Pima Indians
    Emilio Ortega Martinez de Victoria
    Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Phoenix, Arizona, USA
    Diabetes 58:385-93. 2009
    ..We sought to determine whether in a healthy population, adiposity, sex, age, or insulin action is associated with adipose tissue macrophage content (ATMc) and/or markers of macrophage activation...
  22. ncbi Increased fat accumulation in liver may link insulin resistance with subcutaneous abdominal adipocyte enlargement, visceral adiposity, and hypoadiponectinemia in obese individuals
    Juraj Koska
    Obesity and Diabetes Clinical Research Section, NIDDK NIH DHHS, Phoenix, AZ 85016, USA
    Am J Clin Nutr 87:295-302. 2008
    ....
  23. ncbi Nighttime eating: commonly observed and related to weight gain in an inpatient food intake study
    Marci E Gluck
    Obesity and Diabetes Clinical Research Section, Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Phoenix, AZ 85016, USA
    Am J Clin Nutr 88:900-5. 2008
    ..Nighttime food intake has rarely been studied in inpatient settings and only one study observed a relation between self-reported nighttime eating and weight gain...
  24. ncbi Morning ghrelin concentrations are not affected by short-term overfeeding and do not predict ad libitum food intake in humans
    Susanne B Votruba
    National Institute of Diabetes and Digestive and Kidney Diseases, Phoenix, AZ 85016, USA
    Am J Clin Nutr 89:801-6. 2009
    ..Ghrelin has a short-term orexigenic effect but may also be a marker of food intake over time. We previously found an inverse association between ghrelin concentrations and food intake...
  25. ncbi Childhood predictors of adult acute insulin response and insulin action
    Marie S Thearle
    Obesity and Diabetes Clinical Research Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona, USA
    Diabetes Care 32:938-43. 2009
    ....
  26. ncbi Effects of metformin on body weight and body composition in obese insulin-resistant children: a randomized clinical trial
    Jack A Yanovski
    Unit on Growth and Obesity, Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development NICHD, Bethesda, Maryland, USA
    Diabetes 60:477-85. 2011
    ..Our objective was to determine whether metformin treatment causes weight loss and improves obesity-related comorbidities in obese children, who are insulin-resistant...
  27. ncbi Reproducibility of ad libitum energy intake with the use of a computerized vending machine system
    Colleen A Venti
    National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Phoenix, AZ, USA
    Am J Clin Nutr 91:343-8. 2010
    ..Accurate assessment of energy intake is difficult but critical for the evaluation of eating behavior and intervention effects. Consequently, methods to assess ad libitum energy intake under controlled conditions have been developed...
  28. ncbi Assessment of non-insulin-mediated glucose uptake: association with body fat and glycemic status
    Reiner Jumpertz
    Obesity and Diabetes Clinical Research Section, National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Phoenix, AZ 85016, USA
    Metabolism 59:1396-401. 2010
    ..Our results indicate that NIMGU is associated with adiposity. NIMGU increases with declining glucose tolerance perhaps to preserve glucose uptake during increased insulin resistance...
  29. ncbi Higher 24-h respiratory quotient and higher spontaneous physical activity in nighttime eaters
    Marci E Gluck
    Obesity and Diabetes Clinical Research Section, Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona, USA
    Obesity (Silver Spring) 19:319-23. 2011
    ..There were no differences in adjusted 24-h EE or sleep RQ between the groups. Individuals with nighttime eating behavior have higher 24-h RQ, higher CHOX and lower LIPOX, a phenotype associated with increased food intake and weight gain...
  30. ncbi Central and peripheral endocannabinoids and cognate acylethanolamides in humans: association with race, adiposity, and energy expenditure
    Reiner Jumpertz
    Obesity and Diabetes Clinical Research Section, National Institutes of Health National Institute of Diabetes and Digestive and Kidney Diseases Department of Health and Human Services, 4212 North 16th Street, Phoenix, Arizona 85016, USA
    J Clin Endocrinol Metab 96:787-91. 2011
    ..Peripheral and central endocannabinoids and cognate acylethanolamides (AEs) may play important but distinct roles in regulating energy balance...
  31. ncbi Markers of adipose tissue macrophage content are negatively associated with serum HDL-C concentrations
    Jianying He
    Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Phoenix, AZ 85016, USA
    Atherosclerosis 215:243-6. 2011
    ..We examined whether abdominal subcutaneous adipose tissue macrophage content (ATMc) was associated with fasting serum total cholesterol (TC), high density lipoprotein (HDL-C) and triglycerides (TG) concentrations...
  32. ncbi Less activation in the left dorsolateral prefrontal cortex in the reanalysis of the response to a meal in obese than in lean women and its association with successful weight loss
    Duc Son Nt Le
    Obesity and Diabetes Clinical Research Section, Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Health, Phoenix, AZ 85016, USA
    Am J Clin Nutr 86:573-9. 2007
    ....
  33. ncbi Higher fasting plasma concentrations of glucagon-like peptide 1 are associated with higher resting energy expenditure and fat oxidation rates in humans
    Nicola Pannacciulli
    Obesity and Diabetes Clinical Research Section, Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, AZ 85016, USA
    Am J Clin Nutr 84:556-60. 2006
    ..Glucagon-like peptide 1 (GLP-1) is a gut hormone that decreases appetite and promotes satiety. Its role in energy metabolism regulation is still poorly understood...
  34. ncbi Effect of youth-onset type 2 diabetes mellitus on incidence of end-stage renal disease and mortality in young and middle-aged Pima Indians
    Meda E Pavkov
    Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Ariz 85014 4972, USA
    JAMA 296:421-6. 2006
    ..The long-term outcome of persons with youth-onset type 2 diabetes mellitus has not been well described...
  35. ncbi Lower total fasting plasma adiponectin concentrations are associated with higher metabolic rates
    Nicola Pannacciulli
    Obesity and Diabetes Clinical Research Section, Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH DHHS, 4212 North 16th Street, Phoenix, AZ 85016, USA
    J Clin Endocrinol Metab 91:1600-3. 2006
    ..The possible role of adiponectin, a protein uniquely produced by the adipose tissue and significantly reduced in obesity and other insulin-resistant states, in the regulation of energy expenditure (EE) is still poorly understood...
  36. ncbi Predominant effect of kidney disease on mortality in Pima Indians with or without type 2 diabetes
    Meda E Pavkov
    Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona 85014 4972, USA
    Kidney Int 68:1267-74. 2005
    ..We examined the effect of kidney disease (KD) on mortality in nondiabetic and diabetic Pima Indians aged > or = 45 years old...
  37. ncbi Early growth in offspring of diabetic mothers
    Leslie Touger
    Diabetes Epidemiology and Clinical Research Section, National Institute of Diabetes and Digestive and Kidney Diseases, 1550 E Indian School Rd, Phoenix, AZ 85014, USA
    Diabetes Care 28:585-9. 2005
    ..By age 5 years, offspring of diabetic mothers (ODMs) are heavier and have altered glucose metabolism compared with offspring of mothers without diabetes (non-DMs). This study evaluates the growth pattern of ODMs before the age of 5 years...
  38. ncbi Hematocrit and the incidence of type 2 diabetes in the pima indians
    Marshall K Tulloch-Reid
    Diabetes and Arthritis Epidemiology Section, Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 1550 East Indian School Rd, Phoenix, AZ 85014, USA
    Diabetes Care 27:2245-6. 2004
  39. ncbi Adiponectin concentrations are influenced by renal function and diabetes duration in Pima Indians with type 2 diabetes
    Helen C Looker
    National Institute of Diabetes and Digestive and Kidney Diseases, Phoenix, Arizona 85014, USA
    J Clin Endocrinol Metab 89:4010-7. 2004
    ..0001). Serum adiponectin is lowest in the presence of impaired glucose regulation and early diabetes. In the presence of diabetes, serum adiponectin is positively associated with abnormal renal function and diabetes duration...
  40. ncbi Longitudinal studies of incidence and progression of diabetic retinopathy assessed by retinal photography in pima indians
    Helen C Looker
    Diabetes and Arthritis Epidemiology Section, National Institute of Diabetes and Digestive and Kidney Diseases, Phoenix, Arizona, USA
    Diabetes Care 26:320-6. 2003
    ..To examine incidence and progression of retinopathy using retinal photographs in Pima Indians and to compare the results with those obtained when retinopathy is assessed by direct ophthalmoscopy...
  41. ncbi Low plasma adiponectin concentrations do not predict weight gain in humans
    Barbora Vozarova
    National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona, USA
    Diabetes 51:2964-7. 2002
    ..Therefore, the predictive effect of low plasma adiponectin concentrations on the development of type 2 diabetes seems to be mediated by factors other than increased adiposity...
  42. ncbi Acute insulin response is an independent predictor of type 2 diabetes mellitus in individuals with both normal fasting and 2-h plasma glucose concentrations
    Joy C Bunt
    Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Phoenix, Arizona 85016, USA
    Diabetes Metab Res Rev 23:304-10. 2007
    ..We wanted to establish whether insulin secretion persists as an independent predictor of T2DM in individuals with no clinical evidence of impaired glucose regulation based on FPG and 2-h plasma glucose concentrations...
  43. ncbi Less activation of the left dorsolateral prefrontal cortex in response to a meal: a feature of obesity
    Duc Son N T Le
    Obesity and Diabetes Clinical Research Section, Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Health, Phoenix, AZ 85016, USA
    Am J Clin Nutr 84:725-31. 2006
    ..The subjects received a meal proportional to their body size; therefore, the meal volume was different for each person...
  44. ncbi Adiponectin and development of type 2 diabetes in the Pima Indian population
    Robert S Lindsay
    National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 1550 East Indian School Road, Phoenix, AZ 85014, USA
    Lancet 360:57-8. 2002
    ..01) and individuals with high concentrations of this protein were less likely to develop type 2 diabetes than those with low concentrations (incidence rate ratio 0.63 [95% CI 0.43-0.92]; p=0.02)...
  45. ncbi Plasma concentrations of free triiodothyronine predict weight change in euthyroid persons
    Emilio Ortega
    Phoenix Epidemiological Clinical and Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Phoenix, AZ 85016, USA
    Am J Clin Nutr 85:440-5. 2007
    ..Factors that influence energy metabolism and substrate oxidation, such as thyroid hormones (THs), may be important regulators of body weight...
  46. ncbi Postprandial glucagon-like peptide-1 (GLP-1) response is positively associated with changes in neuronal activity of brain areas implicated in satiety and food intake regulation in humans
    Nicola Pannacciulli
    Obesity and Diabetes Clinical Research Section, NIDDK NIH, DHHS, 4212 N 16th St Phoenix, AZ 85016, USA
    Neuroimage 35:511-7. 2007
    ..The postprandial GLP-1 response is associated with activation of areas of the human brain previously implicated in satiation and food intake regulation...
  47. ncbi Glucose response to an oral glucose tolerance test predicts weight change in non-diabetic subjects
    Nicola Pannacciulli
    Obesity and Diabetes Clinical Research Section, Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona 85016, USA
    Obesity (Silver Spring) 15:632-9. 2007
    ..Whether blood glucose affects long-term regulation of body weight in humans remains to be established. We sought to test the hypothesis that the post-challenge glucose response is a predictor of weight change...
  48. ncbi Changing patterns of type 2 diabetes incidence among Pima Indians
    Meda E Pavkov
    Diabetes Epidemiology and Clinical Research Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 1550 East Indian School Rd, Phoenix, AZ 85014 4972, USA
    Diabetes Care 30:1758-63. 2007
    ..We examined trends in the incidence rate of type 2 diabetes among Pima Indians between 1965 and 2003...
  49. ncbi Relationships between plasma leptin concentrations and human brain structure: a voxel-based morphometric study
    Nicola Pannacciulli
    Obesity and Diabetes Clinical Research Section, Phoenix Epidemiology and Clinical Research Branch, NIDDK NIH, Phoenix, AZ 85016, United States
    Neurosci Lett 412:248-53. 2007
    ..These relationships may explain some of the abnormalities in brain morphology recently found to be associated with excess body fatness...
  50. ncbi The effect of insulin on net lipid oxidation predicts worsening of insulin resistance and development of type 2 diabetes mellitus
    Juraj Koska
    Obesity and Diabetes Clinical Research Section, NIDDK NIH DHHS, 4212 N 16th St, Rm 5 35, Phoenix, AZ 85016, USA
    Am J Physiol Endocrinol Metab 293:E264-9. 2007
    ..04). These data indicate that the inability of insulin to suppress L(ox) may represent an early risk marker for insulin resistance and T2DM that is independent of adiposity, acute insulin secretion, and insulin action on glucose uptake...
  51. ncbi Comparison of plasma insulin levels after a mixed-meal challenge in children with and without intrauterine exposure to diabetes
    A D Salbe
    NIH NIDDK Obesity and Diabetes Clinical Research Section, 4212 North 16th Street, Room 541, Phoenix, Arizona 85016, USA
    J Clin Endocrinol Metab 92:624-8. 2007
    ..The diabetic intrauterine environment is a known risk factor for the development of diabetes in the offspring...
  52. ncbi Genome-wide linkage analysis of serum adiponectin in the Pima Indian population
    Robert S Lindsay
    National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona 85014, USA
    Diabetes 52:2419-25. 2003
    ..Our data suggest that quantitative trait loci on chromosomes 2, 3, 9, and 10 may influence circulating adiponectin concentrations in the Pima population...
  53. ncbi Effects of binge eating on satiation, satiety, and energy intake of overweight children
    Margaret C Mirch
    Growth and Obesity, Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892-1103, USA
    Am J Clin Nutr 84:732-8. 2006
    ..004). CONCLUSION: The ability to consume large quantities of palatable foods, coupled with decreased subsequent satiety, may play a role in the greater weight gain found in binge-eating children...
  54. ncbi Depression, diabetes, and glycemic control in Pima Indians
    Puneet K Singh
    Diabetes Care 27:618-9. 2004
  55. ncbi Health-related quality of life of children and adolescents with type 1 or type 2 diabetes mellitus: SEARCH for Diabetes in Youth Study
    Michelle J Naughton
    Department of Social Sciences and Health Policy, Division of Public Health Sciences, Wake Forest University School of Medicine, 2000 W First St, Winston Salem, NC 27104, USA
    Arch Pediatr Adolesc Med 162:649-57. 2008
    ..To examine the associations between demographic and diabetes management variables and the health-related quality of life (HRQOL) of youths with type 1 or type 2 diabetes mellitus (DM)...
  56. ncbi Extension of type 2 diabetes genome-wide association scan results in the diabetes prevention program
    Allan F Moore
    Center for Human Genetic Research, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA
    Diabetes 57:2503-10. 2008
    ....