M Kraft

Summary

Affiliation: National Jewish Medical and Research Center
Country: USA

Publications

  1. ncbi request reprint Physiologic correlates of distal lung inflammation in asthma
    E Rand Sutherland
    Department of Medicine, National Jewish Medical and Research Center, 1400 Jackson Street, J 217, Denver, CO 80206, USA
    J Allergy Clin Immunol 113:1046-50. 2004
  2. ncbi request reprint The role of bacterial infections in asthma
    M Kraft
    Department of Medicine, National Jewish Medical and Research Center, University of Colorado Health Sciences Center, Denver, USA
    Clin Chest Med 21:301-13. 2000
  3. ncbi request reprint Airway tissue mast cells in persistent asthma: predictor of treatment failure when patients discontinue inhaled corticosteroids
    Monica Kraft
    National Jewish Medical and Research Center, Denver, CO 80206, USA
    Chest 124:42-50. 2003
  4. ncbi request reprint Distal lung dysfunction at night in nocturnal asthma
    M Kraft
    Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Health Sciences Center, National Jewish Medical and Research Center, Denver, Colorado 80206, USA
    Am J Respir Crit Care Med 163:1551-6. 2001
  5. ncbi request reprint Decreased steroid responsiveness at night in nocturnal asthma. Is the macrophage responsible?
    M Kraft
    Departments of Medicine and Pediatrics, National Jewish Medical and Research Center, Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Health Sciences Center, Denver, Colorado, USA
    Am J Respir Crit Care Med 163:1219-25. 2001
  6. ncbi request reprint Corticosteroids and leukotrienes: chronobiology and chronotherapy
    M Kraft
    Department of Medicine, National Jewish Medical and Research Center, University of Colorado Health Sciences Center, Denver 80206, USA
    Chronobiol Int 16:683-93. 1999
  7. ncbi request reprint Serum cortisol in asthma: marker of nocturnal worsening of symptoms and lung function?
    M Kraft
    Department of Medicine, National Jewish Center for Immunology and Respiratory Medicine and University of Colorado Health Sciences Center, Denver 80206, USA
    Chronobiol Int 15:85-92. 1998
  8. ncbi request reprint Detection of Mycoplasma pneumoniae in the airways of adults with chronic asthma
    M Kraft
    Department of Medicine, National Jewish Medical and Research Center and the University of Colorado Health Sciences Center, Denver, Colorado, USA
    Am J Respir Crit Care Med 158:998-1001. 1998
  9. ncbi request reprint Serum lidocaine concentrations in asthmatics undergoing research bronchoscopy
    E L Langmack
    Department of Medicine, National Jewish Medical and Research Center, Denver, CO 80206, USA
    Chest 117:1055-60. 2000
  10. ncbi request reprint Evaluation of blood vessels and edema in the airways of asthma patients: regulation with clarithromycin treatment
    H W Chu
    Department of Medicine, National Jewish Medical and Research Center, Denver, CO 80206, USA
    Chest 120:416-22. 2001

Detail Information

Publications49

  1. ncbi request reprint Physiologic correlates of distal lung inflammation in asthma
    E Rand Sutherland
    Department of Medicine, National Jewish Medical and Research Center, 1400 Jackson Street, J 217, Denver, CO 80206, USA
    J Allergy Clin Immunol 113:1046-50. 2004
    ..The distal lung is an important site of inflammation in asthma. Maximal midexpiratory flows and the ratio of maximal:partial flows are purported to reflect distal lung function...
  2. ncbi request reprint The role of bacterial infections in asthma
    M Kraft
    Department of Medicine, National Jewish Medical and Research Center, University of Colorado Health Sciences Center, Denver, USA
    Clin Chest Med 21:301-13. 2000
    ..Many questions remain, but the ground is fertile for continued investigation...
  3. ncbi request reprint Airway tissue mast cells in persistent asthma: predictor of treatment failure when patients discontinue inhaled corticosteroids
    Monica Kraft
    National Jewish Medical and Research Center, Denver, CO 80206, USA
    Chest 124:42-50. 2003
    ..To determine if persistent airway tissue mast cells are associated with treatment failure when patients discontinue inhaled corticosteroids (ICS)...
  4. ncbi request reprint Distal lung dysfunction at night in nocturnal asthma
    M Kraft
    Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Health Sciences Center, National Jewish Medical and Research Center, Denver, Colorado 80206, USA
    Am J Respir Crit Care Med 163:1551-6. 2001
    ..M. (r = 0.71, p = 0.004) and 4:00 A.M. (r = 0.59, p = 0.03). We conclude that the distal lung units, specifically the collateral channels, and may be functionally altered at night in NA...
  5. ncbi request reprint Decreased steroid responsiveness at night in nocturnal asthma. Is the macrophage responsible?
    M Kraft
    Departments of Medicine and Pediatrics, National Jewish Medical and Research Center, Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Health Sciences Center, Denver, Colorado, USA
    Am J Respir Crit Care Med 163:1219-25. 2001
    ..We conclude that the airway macrophage may be the airway inflammatory cell driving the reduction in steroid responsiveness at night in NA, and this function is modulated by IL-13...
  6. ncbi request reprint Corticosteroids and leukotrienes: chronobiology and chronotherapy
    M Kraft
    Department of Medicine, National Jewish Medical and Research Center, University of Colorado Health Sciences Center, Denver 80206, USA
    Chronobiol Int 16:683-93. 1999
    ..However, they have not been evaluated chronotherapeutically. This article addresses the roles of corticosteroids and leukotrienes in nocturnal asthma and their position as therapeutic agents or targets for therapy...
  7. ncbi request reprint Serum cortisol in asthma: marker of nocturnal worsening of symptoms and lung function?
    M Kraft
    Department of Medicine, National Jewish Center for Immunology and Respiratory Medicine and University of Colorado Health Sciences Center, Denver 80206, USA
    Chronobiol Int 15:85-92. 1998
    ..Therefore, serum levels of cortisol may not be the appropriate measurement to assess the role of cortisol in nocturnal asthma...
  8. ncbi request reprint Detection of Mycoplasma pneumoniae in the airways of adults with chronic asthma
    M Kraft
    Department of Medicine, National Jewish Medical and Research Center and the University of Colorado Health Sciences Center, Denver, Colorado, USA
    Am J Respir Crit Care Med 158:998-1001. 1998
    ..pneumoniae (p = 0.05). M. pneumoniae was present in the lower airways of chronic, stable asthmatics with greater frequency than control subjects, and may play a role in the pathogenesis of chronic asthma...
  9. ncbi request reprint Serum lidocaine concentrations in asthmatics undergoing research bronchoscopy
    E L Langmack
    Department of Medicine, National Jewish Medical and Research Center, Denver, CO 80206, USA
    Chest 117:1055-60. 2000
    ....
  10. ncbi request reprint Evaluation of blood vessels and edema in the airways of asthma patients: regulation with clarithromycin treatment
    H W Chu
    Department of Medicine, National Jewish Medical and Research Center, Denver, CO 80206, USA
    Chest 120:416-22. 2001
    ..Clarithromycin treatment in asthmatic patients could reduce the edematous area as identified by alpha(2)-macroglobulin staining, which may lead to airway tissue shrinkage and cause an artificial increase in the number of blood vessels...
  11. pmc Body mass index and phenotype in subjects with mild-to-moderate persistent asthma
    E Rand Sutherland
    National Jewish Health, Denver, CO 80206, USA
    J Allergy Clin Immunol 123:1328-34.e1. 2009
    ..Although obesity has been hypothesized to worsen asthma, data from studies of subjects with well-characterized asthma are lacking...
  12. ncbi request reprint A link between chronic asthma and chronic infection
    R J Martin
    Department of Medicine, National Jewish Medical and Research Center and The Pulmonary and Critical Care Division, University of Colorado Health Sciences Center, 1400 Jackson St, Denver, CO 80206, USA
    J Allergy Clin Immunol 107:595-601. 2001
    ..These findings need further delineation but may help us to understand the pathophysiology of asthma and new treatment options...
  13. ncbi request reprint IL-4, IL-13, and dexamethasone augment fibroblast proliferation in asthma
    M Kraft
    Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Health Sciences Center, 1400 Jackson St, Denver, CO 80206, USA
    J Allergy Clin Immunol 107:602-6. 2001
    ..02; 10(-8) mol/L, P =.02). IFN-gamma did not significantly alter airway fibroblast proliferation. CONCLUSION: IL-4, IL-13, and dexamethasone all significantly increased fibroblast proliferation in subjects with mild asthma...
  14. ncbi request reprint Magnesium attenuates the neutrophil respiratory burst in adult asthmatic patients
    C B Cairns
    Division of Emergency Medicine, University of Colorado Health Sciences Center, Denver 80262, USA
    Acad Emerg Med 3:1093-7. 1996
    ..IV magnesium (Mg2+) has been proposed as an emergent treatment for acute asthma exacerbations. Recent studies have focused on the effects of Mg2+ on bronchial smooth muscle, yet asthma is primarily an inflammatory disease...
  15. ncbi request reprint Quality control within the Asthma Clinical Research Network
    R J Martin
    National Jewish Medical and Research Center, Denver, CO 80206, USA
    Control Clin Trials 22:207S-21S. 2001
    ..The examples given in this report demonstrate how various aspects of our investigation are performed...
  16. ncbi request reprint Substance P and its receptor neurokinin 1 expression in asthmatic airways
    H W Chu
    Department of Medicine, National Jewish Medical and Research Center and the University of Colorado Health Sciences Center, Denver, CO 80206, USA
    J Allergy Clin Immunol 106:713-22. 2000
    ..In contrast to substance P, the substance P receptor neurokinin 1 has not been examined at the protein level in asthmatic airways...
  17. ncbi request reprint Chronobiology and chronotherapy in medicine
    M Kraft
    Department of Medicine, National Jewish Center for Immunology and Respiratory Medicine, University of Colorado Health Sciences Center, Denver, USA
    Dis Mon 41:506-75. 1995
    ..Thus, all biologic functions, from those of the cell, the tissue, the organs, and the entire body, run on a cycle of altering activity and function.(ABSTRACT TRUNCATED AT 400 WORDS)..
  18. ncbi request reprint Use of regularly scheduled albuterol treatment in asthma: genotype-stratified, randomised, placebo-controlled cross-over trial
    Elliot Israel
    Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Lancet 364:1505-12. 2004
    ..However, the existence of any genotype-dependent difference has not been tested in a prospective clinical trial...
  19. ncbi request reprint Sputum eosinophil counts predict asthma control after discontinuation of inhaled corticosteroids
    Aaron Deykin
    Brigham and Women s Hospital and Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA
    J Allergy Clin Immunol 115:720-7. 2005
    ..Although inhaled corticosteroids (ICSs) are effective in preventing deterioration in asthma control, at least half of subjects with mild-to-moderate asthma will remain stable when these agents are discontinued...
  20. ncbi request reprint Daily versus as-needed corticosteroids for mild persistent asthma
    Homer A Boushey
    University of California at San Francisco, San Francisco, USA
    N Engl J Med 352:1519-28. 2005
    ....
  21. pmc Investigative bronchoprovocation and bronchoscopy in airway diseases
    William W Busse
    University of Wisconsin Madison, USA
    Am J Respir Crit Care Med 172:807-16. 2005
    ..Since the last critical review more than a decade ago, some of the techniques and applications have changed, and untoward events have occurred, raising safety concerns and increasing institutional review scrutiny...
  22. pmc Combination therapy with a long-acting beta-agonist and a leukotriene antagonist in moderate asthma
    Aaron Deykin
    Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Am J Respir Crit Care Med 175:228-34. 2007
    ..The elements of asthma control achieved by LABAs (improved lung function) and leukotriene receptor antagonists (LTRAs; protection against exacerbations) may be complementary as well...
  23. ncbi request reprint Asthma end points and outcomes: what have we learned?
    Don Bukstein
    Allergy and Asthma Research, Dean Medical Center, Department of Pediatrics and Family Practice, University of Wisconsin Medical School, Madison, Wisconsin, USA
    J Allergy Clin Immunol 118:S1-15. 2006
    ..The fraction of exhaled nitric oxide as a measure of inflammation is suggested as offering the best combination of disease evaluation and practical implementation for improved asthma outcomes...
  24. ncbi request reprint Improvements in distal lung function correlate with asthma symptoms after treatment with oral montelukast
    Monica Kraft
    Department of Medicine, Duke University Medical Center, MSBR M201D, Durham, NC 27710, USA
    Chest 130:1726-32. 2006
    ..We hypothesized that treatment with montelukast, an oral cysteinyl-leukotriene receptor antagonist, would improve both proximal and distal lung physiology in patients with mild asthma...
  25. pmc Smoking affects response to inhaled corticosteroids or leukotriene receptor antagonists in asthma
    Stephen C Lazarus
    University of California, San Francisco, 505 Parnassus Avenue, M 1083, San Francisco, CA 94143 0111, USA
    Am J Respir Crit Care Med 175:783-90. 2007
    ..One-quarter to one-third of individuals with asthma smoke, which may affect response to therapy and contribute to poor asthma control...
  26. pmc The Predicting Response to Inhaled Corticosteroid Efficacy (PRICE) trial
    Richard J Martin
    National Jewish Medical and Research Center, Denver, CO 80206, USA
    J Allergy Clin Immunol 119:73-80. 2007
    ..Although guidelines recommend anti-inflammatory therapy for persistent asthma, recent studies suggest that 25% to 35% of patients with asthma may not improve lung function with inhaled corticosteroids...
  27. ncbi request reprint Clinical Decisions. Treatment of mild persistent asthma
    Monica Kraft
    N Engl J Med 356:2096-100. 2007
  28. ncbi request reprint Part III: Location of asthma inflammation and the distal airways: clinical implications
    Monica Kraft
    Duke Asthma, Allergy, and Airway Center, Duke University, Durham, NC 27710, USA
    Curr Med Res Opin 23:S21-7. 2007
    ..Due to their highly targeted delivery systems, newer HFA-based formulations have the potential to effectively treat asthma at reduced doses...
  29. pmc beta-Adrenergic receptor polymorphisms and response to salmeterol
    Michael E Wechsler
    Brigham and Women s Hospital, 75 Francis Street, Boston, MA, 02115, USA
    Am J Respir Crit Care Med 173:519-26. 2006
    ..Several studies suggest that patients with asthma who are homozygous for arginine at the 16th position of the beta2-adrenergic receptor may not benefit from short-acting beta-agonists...
  30. ncbi request reprint Effects of treatment with anti-immunoglobulin E antibody omalizumab on airway inflammation in allergic asthma
    Ratko Djukanovic
    Respiratory Cell and Molecular Biology, Division of Infection, Inflammation, and Repair, University of Southampton, Southampton, UK
    Am J Respir Crit Care Med 170:583-93. 2004
    ..The lack of effect of omalizumab on methacholine responsiveness suggests that IgE or eosinophils may not be causally linked to airway hyperresponsiveness to methacholine in mild to moderate asthma...
  31. ncbi request reprint Systemic effect comparisons of six inhaled corticosteroid preparations
    Richard J Martin
    National Jewish Medical and Research Center, Denver, Colorado 80206, USA
    Am J Respir Crit Care Med 165:1377-83. 2002
    ..This study represents the first step in evaluation of ICS efficacy based on equisystemic (cortisol suppression) effects of a given ICS, rather than doses judged arbitrarily to be comparable on a microgram basis...
  32. ncbi request reprint Mycoplasma pneumoniae and Chlamydia pneumoniae in asthma: effect of clarithromycin
    Monica Kraft
    Department of Medicine, National Jewish Medical and Research Center and the University of Colorado Health Sciences Center, Denver, CO 80206, USA
    Chest 121:1782-8. 2002
    ..To determine the effect of clarithromycin therapy in patients with asthma...
  33. ncbi request reprint Immunomodulatory effects of melatonin in asthma
    E Rand Sutherland
    Department of Medicine, National Jewish Medical and Research Center, Denver, CO, USA
    Am J Respir Crit Care Med 166:1055-61. 2002
    ..M., suggesting chronic overstimulation in vivo. These results suggest differential immunomodulatory effects of melatonin based on asthma clinical phenotype and may indicate an adverse effect of exogenous melatonin in asthma...
  34. ncbi request reprint Increased matrix metalloproteinase-9 with elastolysis in nocturnal asthma
    David N Pham
    Department of Medicine, National Jewish Medical and Research Center, Denver, Colorado 80206, USA
    Ann Allergy Asthma Immunol 90:72-8. 2003
    ....
  35. ncbi request reprint Interleukin-4 and interleukin-13 augment the proliferative effect of dexamethasone on distal lung fibroblasts
    Christina C Lewis
    National Jewish Medical and Research Center, Denver, CO 80206, USA
    Chest 123:356S. 2003
  36. ncbi request reprint Significant variability in response to inhaled corticosteroids for persistent asthma
    Stanley J Szefler
    National Jewish Medical and Research Center, Department of Pediatrics, Denver, CO 80206, USA
    J Allergy Clin Immunol 109:410-8. 2002
    ..A clinical model is needed to compare inhaled corticosteroids (ICSs) with respect to efficacy...
  37. ncbi request reprint Elevated serum melatonin is associated with the nocturnal worsening of asthma
    E Rand Sutherland
    Department of Pediatrics, National Jewish Medical and Research Center, 1400 Jackson Street, Denver, CO 80206, USA
    J Allergy Clin Immunol 112:513-7. 2003
    ..In vitro studies have shown exogenous melatonin to be pro-inflammatory in asthma, but it is unknown whether endogenous melatonin levels are a controller of airway inflammation in nocturnal asthma...
  38. ncbi request reprint Altered pituitary-adrenal interaction in nocturnal asthma
    E Rand Sutherland
    Department of Medicine, National Jewish Medical and Research Center, University of Colorado Health Sciences Center, Denver, USA
    J Allergy Clin Immunol 112:52-7. 2003
    ..Increased airway inflammation at night contributes to the nocturnal worsening of asthma, but the mechanisms regulating circadian variations in airway inflammation are unknown...
  39. ncbi request reprint Induction of regulated upon activation, normal T cells expressed and secreted (RANTES) and transforming growth factor-beta 1 in airway epithelial cells by Mycoplasma pneumoniae
    Azzeddine Dakhama
    Department of Pediatrics, National Jewish Medical and Research Center, Denver, CO 80206, USA
    Am J Respir Cell Mol Biol 29:344-51. 2003
    ..These results suggest that M. pneumoniae infection may contribute to the pathogenesis of chronic asthma at different levels of the airways, by inducing TGF-beta1 in large airways and the chemokine RANTES in small airways...
  40. ncbi request reprint Hypothalamic-pituitary-adrenal axis dysfunction during sleep in nocturnal asthma
    E Rand Sutherland
    National Jewish Medical and Research Center, Denver, CO 80206, USA
    Chest 123:405S. 2003
  41. ncbi request reprint Airway fibroblasts exhibit a synthetic phenotype in severe asthma
    Christina C Lewis
    Division of Pulmonary Sciences and Critical Care Medicine, National Jewish Medical and Research Center, Denver, Colo, USA
    J Allergy Clin Immunol 115:534-40. 2005
    ..Platelet-derived growth factor (PDGF) may have a significant role in airway remodeling in asthma, because it is a powerful inductor of many airway fibroblast activities such as collagen synthesis...
  42. ncbi request reprint Cysteinyl leukotrienes in allergic inflammation: strategic target for therapy
    William Busse
    University of Wisconsin, Madison Medical School, Department of Medicine, 15 220 Clinical Science Center, 600 Highland Ave, Madison, WI 53792 2454, USA
    Chest 127:1312-26. 2005
    ..The mechanism of action of LTRAs leads to their effects on systemic allergic inflammatory processes...
  43. ncbi request reprint Cysteinyl leukotriene expression in chronic hyperplastic sinusitis-nasal polyposis: importance to eosinophilia and asthma
    John W Steinke
    Asthma and Allergic Disease Center, Beirne Carter Center for Immunology, University of Virginia Health System, Charlottesville, VA 22908, USA
    J Allergy Clin Immunol 111:342-9. 2003
    ..The frequent coexpression of these disorders and their shared pathophysiology suggests that these are similar disorders affecting the upper and lower airways...
  44. ncbi request reprint Introduction: asthma in the new millennium
    Richard J Martin
    National Jewish Medical and Research Center, University of Colorado Health Science Center, Denver, CO 80206, USA
    Chest 123:339S. 2003
  45. ncbi request reprint Asthma and chronic obstructive pulmonary disease exhibit common origins in any country!
    Monica Kraft
    Am J Respir Crit Care Med 174:238-40; discussion 243-4. 2006
  46. ncbi request reprint Increased expression of platelet-derived growth factor receptor-beta in airway fibroblasts of severe asthmatics
    Christina C Lewis
    National Jewish Medical and Research Center, Denver, CO 80206, USA
    Chest 123:428S-9S. 2003
  47. ncbi request reprint Airway remodeling from bench to bedside: current perspectives
    David J Slade
    Department of Pediatrics, Division of Pulmonology, Duke University Medical Center, Durham, NC 27710, USA
    Clin Chest Med 27:71-85, vi. 2006
    ..Although steroid therapy is helpful in symptomatic control, it does not remedy structural alterations or many aspects of the inflammatory milieu. This article discusses several studies and supports the need for further investigation...
  48. ncbi request reprint Epidemiology of asthma
    Njira L Lugogo
    Division of Pulmonary, Allergy, and Critical Care Medicine, Duke University Medical Center, P O Box 2641, Durham, NC 27710, USA
    Clin Chest Med 27:1-15, v. 2006
    ..The analysis of data collected from epidemiologic studies continues to be a critical part of enhancing the understanding of the pathophysiology of asthma, which will lead to improved patient outcomes...
  49. ncbi request reprint Mycoplasma in severe asthma
    Monica Kraft
    Allergy and Airway Center, Duke University Medical Center, Durham, NC, USA
    J Allergy Clin Immunol 117:1197-8. 2006