Jeffrey B Kopp

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc APOL1 genetic variants in focal segmental glomerulosclerosis and HIV-associated nephropathy
    Jeffrey B Kopp
    Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Disease, National Institutes of Health, Bethesda, Maryland, USA
    J Am Soc Nephrol 22:2129-37. 2011
  2. doi request reprint Glomerular disease in 2012: more mechanistic insights, but translational progress is slow
    Jeffrey B Kopp
    National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892 1268, USA
    Nat Rev Nephrol 9:67-8. 2013
  3. pmc Angiotensin II overcomes strain-dependent resistance of rapid CKD progression in a new remnant kidney mouse model
    Asada Leelahavanichkul
    Renal Diagnostics and Therapeutics Unit, Kidney Disease Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892 1268, USA
    Kidney Int 78:1136-53. 2010
  4. pmc Urinary exosomal transcription factors, a new class of biomarkers for renal disease
    Hua Zhou
    Renal Diagnostics and Therapeutics Unit, National Institutes of Health, Bethesda, Maryland, USA
    Kidney Int 74:613-21. 2008
  5. pmc Chronic kidney disease worsens sepsis and sepsis-induced acute kidney injury by releasing High Mobility Group Box Protein-1
    Asada Leelahavanichkul
    Renal Diagnostics and Therapeutics Unit, National Institutes of Health, Bethesda, Maryland 20892 1268, USA
    Kidney Int 80:1198-211. 2011
  6. pmc Cell-cell contact regulates gene expression in CDK4-transformed mouse podocytes
    Toru Sakairi
    Kidney Disease Section, Kidney Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland, USA
    Am J Physiol Renal Physiol 299:F802-9. 2010
  7. ncbi request reprint Kidney patient care in disasters: emergency planning for patients and dialysis facilities
    Jeffrey B Kopp
    Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892 1268, USA
    Clin J Am Soc Nephrol 2:825-38. 2007
  8. pmc MYH9 is a major-effect risk gene for focal segmental glomerulosclerosis
    Jeffrey B Kopp
    Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Nat Genet 40:1175-84. 2008
  9. pmc Squirrel monkeys support replication of BK virus more efficiently than simian virus 40: an animal model for human BK virus infection
    Concepcion Zaragoza
    Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 10 3N116, Bethesda, MD 20892 1268
    J Virol 79:1320-6. 2005
  10. pmc Bioenergetic characterization of mouse podocytes
    Yoshifusa Abe
    Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892 1268, USA
    Am J Physiol Cell Physiol 299:C464-76. 2010

Collaborators

Detail Information

Publications53

  1. pmc APOL1 genetic variants in focal segmental glomerulosclerosis and HIV-associated nephropathy
    Jeffrey B Kopp
    Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Disease, National Institutes of Health, Bethesda, Maryland, USA
    J Am Soc Nephrol 22:2129-37. 2011
    ..These data add to the evidence base required to determine whether genetic testing for APOL1 has a use in clinical practice...
  2. doi request reprint Glomerular disease in 2012: more mechanistic insights, but translational progress is slow
    Jeffrey B Kopp
    National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892 1268, USA
    Nat Rev Nephrol 9:67-8. 2013
    ..Progress in glomerular disease has continued, although our understanding of disease processes continues to extend much further than our ability to intervene effectively...
  3. pmc Angiotensin II overcomes strain-dependent resistance of rapid CKD progression in a new remnant kidney mouse model
    Asada Leelahavanichkul
    Renal Diagnostics and Therapeutics Unit, Kidney Disease Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892 1268, USA
    Kidney Int 78:1136-53. 2010
    ..Thus, reducing renal mass in CD-1 or 129S3 mice mimics many features of human CKD. Angiotensin II can convert the C57BL/6 strain from CKD resistant to susceptible in this disease model...
  4. pmc Urinary exosomal transcription factors, a new class of biomarkers for renal disease
    Hua Zhou
    Renal Diagnostics and Therapeutics Unit, National Institutes of Health, Bethesda, Maryland, USA
    Kidney Int 74:613-21. 2008
    ..Measurement of urinary exosomal transcription factors may offer insight into cellular regulatory pathways...
  5. pmc Chronic kidney disease worsens sepsis and sepsis-induced acute kidney injury by releasing High Mobility Group Box Protein-1
    Asada Leelahavanichkul
    Renal Diagnostics and Therapeutics Unit, National Institutes of Health, Bethesda, Maryland 20892 1268, USA
    Kidney Int 80:1198-211. 2011
    ..Thus, progressive CKD increases the severity of sepsis, in part, by reducing the renal clearance of several cytokines. CKD-induced splenic apoptosis and HMGB1 release could be important common mediators for both CKD and sepsis...
  6. pmc Cell-cell contact regulates gene expression in CDK4-transformed mouse podocytes
    Toru Sakairi
    Kidney Disease Section, Kidney Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland, USA
    Am J Physiol Renal Physiol 299:F802-9. 2010
    ..Our findings suggest that CDK4 podocytes are useful tools to study podocyte biology. Furthermore, the role of cell-cell contact in podocyte gene expression may have relevance for podocyte function in vivo...
  7. ncbi request reprint Kidney patient care in disasters: emergency planning for patients and dialysis facilities
    Jeffrey B Kopp
    Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892 1268, USA
    Clin J Am Soc Nephrol 2:825-38. 2007
    ..A timeline to safety for dialysis patients can be visualized; if specific tasks are accomplished at each disaster stage, then it is likely that the health of these vulnerable patients can be protected...
  8. pmc MYH9 is a major-effect risk gene for focal segmental glomerulosclerosis
    Jeffrey B Kopp
    Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Nat Genet 40:1175-84. 2008
    ..2, 95% CI = 1.5-3.4; n = 433), but not type 2 diabetic ESKD (n = 476). Genetic variation at the MYH9 locus substantially explains the increased burden of FSGS and hypertensive ESKD among African Americans...
  9. pmc Squirrel monkeys support replication of BK virus more efficiently than simian virus 40: an animal model for human BK virus infection
    Concepcion Zaragoza
    Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 10 3N116, Bethesda, MD 20892 1268
    J Virol 79:1320-6. 2005
    ..We conclude that the squirrel monkey is a suitable animal for studies of experimental BKV infection and may facilitate studies of viral entry, pathogenesis, and therapy...
  10. pmc Bioenergetic characterization of mouse podocytes
    Yoshifusa Abe
    Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892 1268, USA
    Am J Physiol Cell Physiol 299:C464-76. 2010
    ..Replication of these experiments in primary mouse podocytes yielded similar data. We conclude that mitochondria play the primary role in maintaining podocyte energy homeostasis, while glycolysis makes a lesser contribution...
  11. ncbi request reprint BK virus and SV40 co-infection in polyomavirus nephropathy
    Rui Mei Li
    Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA
    Transplantation 74:1497-504. 2002
    ..The simian virus (SV) 40 is PV that was likely introduced into the human population through contaminated vaccines. The purpose of this study was to identify and characterize the PV that is associated with PV nephropathy...
  12. pmc Pirfenidone: an anti-fibrotic therapy for progressive kidney disease
    Monique E Cho
    National Institutes of Health, Kidney Disease Branch, 10 CRC 5 5750, 9000 Rockville Pike, Bethesda, MD 20892 1268, USA
    Expert Opin Investig Drugs 19:275-83. 2010
    ..Larger studies are needed to better understand long-term efficacy and safety of this medication in various patient populations...
  13. ncbi request reprint NPHS2 variation in sporadic focal segmental glomerulosclerosis
    Louise M McKenzie
    Laboratory of Genomic Diversity, SAIC Frederick, National Cancer Institute, NCI Frederick, Frederick, Maryland, USA
    J Am Soc Nephrol 18:2987-95. 2007
    ..5, P = 0.001). These results indicate that genetic variation or mutation of NPHS2 may play a role in late-onset sporadic FSGS...
  14. pmc Proteomic analysis identifies insulin-like growth factor-binding protein-related protein-1 as a podocyte product
    Takayuki Matsumoto
    Kidney Disease Section, Kidney Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, US Department of Health and Human Services, Bethesda, Maryland, USA
    Am J Physiol Renal Physiol 299:F776-84. 2010
    ..We conclude that IGFBP-rP1 may be a product of injured podocytes. Further analysis of the podocyte secretory proteome may identify biomarkers of podocyte injury...
  15. doi request reprint Urinary exosomal Wilms' tumor-1 as a potential biomarker for podocyte injury
    Hua Zhou
    Renal Diagnostics and Therapeutics Unit, NIDDK, National Institutes of Health, 10 Center Dr, Bldg 10, Rm 3N108, Bethesda, MD 20892 1268
    Am J Physiol Renal Physiol 305:F553-9. 2013
    ..These results warrant longitudinal, prospective studies in a large cohort with a range of podocyte diseases. ..
  16. pmc The Gne M712T mouse as a model for human glomerulopathy
    Sravan Kakani
    Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892 1851, USA
    Am J Pathol 180:1431-40. 2012
    ..Moreover, the partial restoration of glomerular architecture in ManNAc-treated mice highlights ManNAc as a potential treatment for humans affected with disorders of glomerular hyposialylation...
  17. pmc Conditionally immortalized human podocyte cell lines established from urine
    Toru Sakairi
    Kidney Disease Section, Kidney Disease Branch, National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892 1268, USA
    Am J Physiol Renal Physiol 298:F557-67. 2010
    ..Further improvements in the approaches to cell transformation and/or cell culture techniques are needed to allow cultured podocytes to fully reproduce in vivo characteristics...
  18. ncbi request reprint Inducible podocyte-specific gene expression in transgenic mice
    Tetsuya Shigehara
    Kidney Disease Section, Metabolic Diseases Branch, National Institutes of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
    J Am Soc Nephrol 14:1998-2003. 2003
    ..This transgenic system should aid future investigations of podocyte function...
  19. pmc Increased prevalence of albuminuria in HIV-infected adults with diabetes
    Peter S Kim
    National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS ONE 6:e24610. 2011
    ..HIV and type 2 diabetes are known risk factors for albuminuria, but no previous reports have characterized albuminuria in HIV-infected patients with diabetes...
  20. ncbi request reprint Detection and localization of proteinuria by dynamic contrast-enhanced magnetic resonance imaging using MS325
    Yantian Zhang
    Department of Radiology, Warren Grant Magnuson Clinical Center, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    J Am Soc Nephrol 16:1752-7. 2005
    ..If this technique can be successfully applied in human patients, it may allow for the localization of proteinuria after kidney transplant and thereby provide a noninvasive way to detect disease affecting the renal allograft...
  21. pmc TGF-beta1 reduces Wilms' tumor suppressor gene expression in podocytes
    Toru Sakairi
    Kidney Disease Section, Kidney Disease Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA
    Nephrol Dial Transplant 26:2746-52. 2011
    ..We aimed to address whether TGF-beta affects WT1 expression in podocytes...
  22. pmc MYH9 genetic variants associated with glomerular disease: what is the role for genetic testing?
    Jeffrey B Kopp
    Kidney Disease Section, Kidney Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892 1268, USA
    Semin Nephrol 30:409-17. 2010
    ..Such studies will address critical questions pertaining to MYH9-associated kidney disease, including mechanism, course, and response to therapy...
  23. pmc Tetracycline-inducible gene expression in conditionally immortalized mouse podocytes
    Hiroshi Kajiyama
    Kidney Disease Section, Kidney Disease Branch, National Institute of Diabetes, Digestive and Kidney Diseases, Bethesda, MD 20892 1268, USA
    Am J Nephrol 29:153-63. 2009
    ..Conditionally immortalized podocytes are valuable research tools but are difficult to efficiently transfect and do not provide graded transgene expression...
  24. ncbi request reprint Natural history and treatment of renal involvement in Fabry disease
    Mary Branton
    Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    J Am Soc Nephrol 13:S139-43. 2002
  25. pmc Human immunodeficiency virus (HIV)-1 viral protein R suppresses transcriptional activity of peroxisome proliferator-activated receptor {gamma} and inhibits adipocyte differentiation: implications for HIV-associated lipodystrophy
    Shashi Shrivastav
    Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Disease NIH, 10 Center Drive MSC 1268, Bethesda, MD 20892 1268, USA
    Mol Endocrinol 22:234-47. 2008
    ..Vpr may alter sensitivity to insulin and thereby contribute to the development of lipodystrophy and insulin resistance observed in HIV-1-infected patients...
  26. ncbi request reprint Pirfenidone slows renal function decline in patients with focal segmental glomerulosclerosis
    Monique E Cho
    Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892 1268, USA
    Clin J Am Soc Nephrol 2:906-13. 2007
    ..Our objective was to determine whether pirfenidone slows the loss of renal function in focal segmental glomerulosclerosis...
  27. ncbi request reprint Twenty-one-year trend in ESRD due to focal segmental glomerulosclerosis in the United States
    Chagriya Kitiyakara
    Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, The National Institutes of Health, Department of Health and Human Services, Bethesda, MD USA
    Am J Kidney Dis 44:815-25. 2004
    ..In the absence of a population-based estimate of FSGS incidence, we wished to obtain a population-based estimate of incident ESRD cases caused by FSGS (FSGS ESRD) and characterize temporal changes in this group...
  28. pmc HIV-1 Vpr Enhances PPAR╬▓/╬┤-Mediated Transcription, Increases PDK4 Expression, and Reduces PDC Activity
    Shashi Shrivastav
    MD, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892 1268
    Mol Endocrinol 27:1564-76. 2013
    ..These results support the hypothesis that Vpr contributes to impaired energy metabolism and increased energy expenditure in HIV patients. ..
  29. ncbi request reprint Anti-mouse mesangial cell serum induces acute glomerulonephropathy in mice
    Yoshikage Yo
    Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD 20892 1268, USA
    Nephron Exp Nephrol 93:e92-106. 2003
    ..Anti-mouse mesangial cell serum induces glomerulopathy characterized by mesangiolysis and mesangial cell apoptosis, and followed by cellular proliferation...
  30. ncbi request reprint Progressive glomerulonephritis and histiocytic sarcoma associated with macrophage functional defects in CYP1B1-deficient mice
    Jerrold M Ward
    The National Institute of Allergy and Infectious Diseases, NIH and SoBran, Inc, Twinbrook 3, Room 2W 01A, Bethesda, Maryland 20892 8135, USA
    Toxicol Pathol 32:710-8. 2004
    ..The function of CYP1B1 in histiocytes and macrophages may involve both self-tolerance and tumor suppression...
  31. doi request reprint Microalbuminuria in HIV disease
    Colleen Hadigan
    Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health NIH, Department of Critical Care Medicine, NIH, Bethesda, MD, USA
    Am J Nephrol 37:443-51. 2013
    ....
  32. pmc Genetics of focal segmental glomerulosclerosis and human immunodeficiency virus-associated collapsing glomerulopathy: the role of MYH9 genetic variation
    Cheryl A Winkler
    Scientific Applications International Corporation Frederick, Inc, Laboratory of Genomic Diversity, Center for Cancer Research, National Cancer Institute Frederick, National Institutes of Health, Frederick, MD, USA
    Semin Nephrol 30:111-25. 2010
    ..The strong predicted power of MYH9 variation for disease indicates a clear role for genetic testing for these variants in personalized medicine, for assessment of genetic risk, and potentially for diagnosis...
  33. pmc Glomerular pathology in autosomal dominant MYH9 spectrum disorders: what are the clues telling us about disease mechanism?
    Jeffrey B Kopp
    Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892 1268, USA
    Kidney Int 78:130-3. 2010
    ..A better understanding of the disease mechanisms responsible for glomerular injury in autosomal dominant MYH9 syndromes will lead to fuller appreciation of the role of this gene in glomerular biology...
  34. pmc Longitudinal assessment of metabolic abnormalities in adolescents and young adults with HIV-infection acquired perinatally or in early childhood
    David Dimock
    Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA
    Metabolism 60:874-80. 2011
    ..002). Impaired glucose tolerance, insulin resistance, dyslipidemia, and microalbuminuria are common among young adults with HIV. Long-term exposure to therapy may translate into substantial persistent metabolic risk...
  35. ncbi request reprint Parvovirus-B19-associated complications in renal transplant recipients
    Meryl Waldman
    Kidney Disease Section, National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20814 9692, USA
    Nat Clin Pract Nephrol 3:540-50. 2007
    ..Most patients benefit from intravenous immunoglobulin therapy and/or alteration or reduction of immunosuppressive therapy. Conservative therapy might be sufficient in some cases...
  36. ncbi request reprint HIV and the kidney: a status report after 20 years
    Monique E Cho
    Kidney Disease Section, National Institute of Diabetes, Digestive, and Kidney Diseases, National Institutes of Health DHHS, 9000 Rockville Pike, Bethesda, MD 20892, USA
    Curr HIV/AIDS Rep 1:109-15. 2004
    ..Appropriate screening for renal dysfunction can minimize the likelihood of progressive renal injury in all patients with HIV-1 infection...
  37. ncbi request reprint In vitro models of TGF-beta-induced fibrosis suitable for high-throughput screening of antifibrotic agents
    Qihe Xu
    Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Disases, National Institutes of Health, Bethesda, MD 20892 1268, USA
    Am J Physiol Renal Physiol 293:F631-40. 2007
    ..As a proof of principle, chemical inhibitors of Alk5 and the antifibrotic compound tranilast were shown to have inhibitory activities in both assays...
  38. ncbi request reprint Sirolimus therapy of focal segmental glomerulosclerosis is associated with nephrotoxicity
    Monique E Cho
    Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892 1268, USA
    Am J Kidney Dis 49:310-7. 2007
    ..We conclude that sirolimus may be associated with nephrotoxicity in some patients with FSGS, particularly those with prolonged disease duration and prior cyclosporine therapy...
  39. ncbi request reprint Parapelvic kidney cysts: a distinguishing feature with high prevalence in Fabry disease
    Markus Ries
    Developmental and Metabolic Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892 1260, USA
    Kidney Int 66:978-82. 2004
    ..In order to identify key novel renal diagnostic imaging features of Fabry disease, we conducted a cross sectional case-control study of kidney involvement in patients with Fabry disease...
  40. ncbi request reprint Fabry disease in the era of enzyme replacement therapy: a renal perspective
    Monique E Cho
    Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892 1268, USA
    Pediatr Nephrol 19:583-93. 2004
    ..Further research is required to determine optimal dosing protocols for treatment and to establish whether therapy can retard the progression of organ dysfunction, or even prevent these complications altogether...
  41. ncbi request reprint Images in clinical medicine. Fabry's disease
    Jeffrey B Kopp
    National Institutes of Health, Bethesda, MD 20892, USA
    N Engl J Med 349:e20. 2003
  42. pmc Mouse models of MYH9-related disease: mutations in nonmuscle myosin II-A
    Yingfan Zhang
    National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892 1583, USA
    Blood 119:238-50. 2012
    ..Our results show that heterozygous mice with mutations in the myosin motor or filament-forming domain manifest similar hematologic, eye, and kidney phenotypes to humans with MYH9-related disease...
  43. ncbi request reprint Update in podocyte biology: putting one's best foot forward
    Laura Barisoni
    The Johns Hopkins University, Baltimore, Maryland, USA
    Curr Opin Nephrol Hypertens 12:251-8. 2003
    ..The rapidly developing field of podocyte cell biology is reviewed, focusing on papers published in the last 12 months...
  44. pmc Viruses and kidney disease: beyond HIV
    Meryl Waldman
    Kidney Disease Section, National Institute of Diabetes, Digestive, and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892 1268, USA
    Semin Nephrol 28:595-607. 2008
    ..We also discuss an approach to the identification of new viral renal pathogens, using a viral gene chip to identify viral DNA or RNA...
  45. pmc Description of familial keloids in five pedigrees: evidence for autosomal dominant inheritance and phenotypic heterogeneity
    Jason A Clark
    Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA
    BMC Dermatol 9:8. 2009
    ..We wished to determine the inheritance pattern and phenotype of keloids among multigenerational families, as a prelude to a positional mapping strategy to identify candidate genes...
  46. ncbi request reprint Parvovirus B19 and the kidney
    Meryl Waldman
    Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892 1268, USA
    Clin J Am Soc Nephrol 2:S47-56. 2007
    ..Allograft rejection and dysfunction have been reported in association with infection, but a cause-effect relationship has not been proved. Further investigation of the relationship between B19 and kidney disease is warranted...
  47. ncbi request reprint Mice lacking the p53-effector gene Gadd45a develop a lupus-like syndrome
    Jesus M Salvador
    Gene Response Section, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA
    Immunity 16:499-508. 2002
    ....
  48. ncbi request reprint Molecular identification of SV40 infection in human subjects and possible association with kidney disease
    Rui Mei Li
    Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892 1268, USA
    J Am Soc Nephrol 13:2320-30. 2002
    ..This study demonstrates for the first time that human kidney can serve as a reservoir for SV40 replication and that SV40 may contribute to the pathogenesis of kidney disease, particularly FSGS...
  49. ncbi request reprint Trends in the epidemiology of focal segmental glomerulosclerosis
    Chagriya Kitiyakara
    Kidney Disease Section, Epidemiology Research Program, National Institute for Diabetes and Digestive and Kidney Diseases, NIH, DHHS, Bethesda, MD, USA
    Semin Nephrol 23:172-82. 2003
    ..The reasons for the recent increase in idiopathic FSGS and FSGS incident ESRD cases are complex, but these trends are likely caused, at least in part, by a real increase in the incidence of FSGS over the past 10 to 20 years...
  50. ncbi request reprint Natural history of Fabry renal disease: influence of alpha-galactosidase A activity and genetic mutations on clinical course
    Mary H Branton
    Metabolic Diseases Branch, National Institute of Diabetes and Digestive and Kidney Disease, National Institutes of Health, Bethesda, Maryland 20892 1268, USA
    Medicine (Baltimore) 81:122-38. 2002
  51. pmc Rapid isolation of urinary exosomal biomarkers using a nanomembrane ultrafiltration concentrator
    Anita Cheruvanky
    Renal Diagnostics and Therapeutics Unit, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892 1268, USA
    Am J Physiol Renal Physiol 292:F1657-61. 2007
    ..This enhanced method may accelerate the translation of urinary exosomal biomarkers from bench to bedside for the diagnosis, classification, and prognostication of renal diseases...
  52. pmc Lack of A1 adenosine receptors augments diabetic hyperfiltration and glomerular injury
    Robert Faulhaber-Walter
    National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Building 10, Room 4D51, 10 Center Drive, MSC 1370, Bethesda, MD 20892, USA
    J Am Soc Nephrol 19:722-30. 2008
    ..Rather, an A1AR-dependent mechanism, possibly TGF, limits the degree of diabetic hyperfiltration and nephropathy...
  53. ncbi request reprint Kidney patient care in disasters: lessons from the hurricanes and earthquake of 2005
    Jeffrey B Kopp
    Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892 1268, USA
    Clin J Am Soc Nephrol 2:814-24. 2007
    ..With suitable planning, the nephrology community can do much to ensure the continuity of medical care for kidney patients in the face of a wide range of possible natural and human-made disasters...