M B Knable
Affiliation: National Institutes of Health
- Dopamine, the prefrontal cortex and schizophreniaM B Knable
National Institute of Mental Health, Intramural Research Program, Clinical Brain Disorders Branch, Washington, DC 20032, USA
J Psychopharmacol 11:123-31. 1997....
- Extrapyramidal side effects with risperidone and haloperidol at comparable D2 receptor occupancy levelsM B Knable
National Institute of Mental Health, Intramural Research Program, Clinical Brain Disorders Branch, Washington, D C 20032, USA
Psychiatry Res 75:91-101. 1997..Based on these observations, it is concluded that 5-HT2 blockade obtained with risperidone at D2 occupancy rates of 60% and above does not appear to protect against the risk for extrapyramidal side effects...
- Are mental diseases brain diseases? The contribution of neuropathology to understanding of schizophrenic psychosesM B Knable
National Institute of Mental Health, National Institutes of Health, Clinical Brain Disorders Branch, Washington, D C, USA
Eur Arch Psychiatry Clin Neurosci 245:224-30. 1995..The hypothesis that emerges from these studies is that schizophrenia is a developmental abnormality affecting the connectivity of the prefrontal and medial temporal cortices...
- Reduced central serotonin transporters in alcoholismA Heinz
Clinical Brain Disorders Branch, NIMH, Washington, D C, USA
Am J Psychiatry 155:1544-9. 1998..The authors explored whether serotonergic dysfunction is associated with anxiety and depression, which increase the risk of relapse in alcoholics...