Research Topics
Species | Ruth A KleinermanSummaryAffiliation: National Institutes of Health Country: USA Publications
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Publications
Sarcomas in hereditary retinoblastomaRuth A Kleinerman
Epidemiology and Biostatistics Program Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Boulevard, Rockville, MD 20852, USA
Clin Sarcoma Res 2:15. 2012..Given the excellent survival of most Rb patients treated in the past, it is important for survivors, their families and health care providers to be aware of the heightened risk for sarcomas in hereditary patients...- Variation of second cancer risk by family history of retinoblastoma among long-term survivorsRuth A Kleinerman
National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA
J Clin Oncol 30:950-7. 2012..To evaluate the risk of second cancer (SC) in long-term survivors of retinoblastoma (Rb) according to classification of germline mutation, based on family history of Rb and laterality... - Cancer risks following diagnostic and therapeutic radiation exposure in childrenRuth A Kleinerman
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, EPS 7044, 6120 Executive Blvd, Rockville, MD 20852, USA
Pediatr Radiol 36:121-5. 2006..Risks of radiation-related cancer are greatest for those exposed early in life, and these risks appear to persist throughout life... 
Risk of soft tissue sarcomas by individual subtype in survivors of hereditary retinoblastomaRuth A Kleinerman
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, EPS 7044, 6120 Executive Blvd, Rockville, MD 20852, USA
J Natl Cancer Inst 99:24-31. 2007..Survivors of hereditary retinoblastoma have an increased risk for second malignancies, especially soft tissue sarcomas. However, the risks of individual histologic subtypes of soft tissue sarcomas have not been evaluated...- Risk of new cancers after radiotherapy in long-term survivors of retinoblastoma: an extended follow-upRuth A Kleinerman
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852 7362, USA
J Clin Oncol 23:2272-9. 2005..We have extended the follow-up of a large cohort of Rb patients for 7 more years to provide new information on the risk of additional cancers after radiotherapy in long-term survivors... - Self-reported electrical appliance use and risk of adult brain tumorsRuth A Kleinerman
Radiation Epidemiology Branch, National Cancer Institute, National Institutes of Health, 6120 Executive Boulevard, EPS 7044, Rockville, MD 20852 7238, USA
Am J Epidemiol 161:136-46. 2005..Overall, results indicate that extremely low frequency electromagnetic fields from commonly used household appliances are unlikely to increase the risk of brain tumors... - Radiation-sensitive genetically susceptible pediatric sub-populationsRuth A Kleinerman
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, MD 20852, USA
Pediatr Radiol 39:S27-31. 2009..Clinicians following these patients should be aware of their increased genetic susceptibility to multiple primary malignancies enhanced by sensitivity to ionizing radiation... - Lung cancer and indoor exposure to coal and biomass in rural ChinaRuth A Kleinerman
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, EPS 7044, MSC 7238, Bethesda, MD 20892, USA
J Occup Environ Med 44:338-44. 2002..The risk for lung cancer increased relative to the percentage of time that coal was used over the past 30 years (P = 0.02). Our findings suggest that coal may contribute to the risk of lung cancer in this rural area of China... - Cause-specific mortality in long-term survivors of retinoblastomaChu Ling Yu
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health DHHS, 6120 Executive Blvd, Rockville, MD 20892 7238, USA
J Natl Cancer Inst 101:581-91. 2009..Radiotherapy further increases the risk of death. Mortality information is limited among long-term survivors who were irradiated for hereditary retinoblastoma... - [Influence of menstrual and reproductive factors on the risk of lung cancer]Alina V Brenner
Radiation Epidemiology Branch, Divison of Cancer Epidemiology and Genetics, National Cancer Institute, USA
Zhonghua Liu Xing Bing Xue Za Zhi 25:590-3. 2004..015) and later ages at menopause (trend, P = 0.074). CONCLUSION: Despite limitations, these findings suggested a possible role related to hormones in the etiology of lung cancer in females... - Analysis of dose response for circulatory disease after radiotherapy for benign diseaseMark P Little
Radiation Epidemiology Branch, National Cancer Institute, Executive Plaza South, Rockville, Maryland, USA
Int J Radiat Oncol Biol Phys 84:1101-9. 2012..To assess the shape of the dose-response for various circulatory disease endpoints, and modifiers by age and time since exposure... - Risk of cataract extraction among adult retinoblastoma survivorsGabriel Chodick
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 7238, USA
Arch Ophthalmol 127:1500-4. 2009..To investigate the risk of cataract extraction among adult retinoblastoma survivors... - Second cancers after squamous cell carcinoma and adenocarcinoma of the cervixAnil K Chaturvedi
Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Blvd, EPS 7072, Rockville, MD 20852, USA
J Clin Oncol 27:967-73. 2009..We assessed whether these cofactor differences translate into differences in second cancer risk... - Cooking oil fumes and risk of lung cancer in women in rural Gansu, ChinaCatherine Metayer
Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Rockville EPS/7044, Bethesda, MD 20892, USA
Lung Cancer 35:111-7. 2002..09). Women exposed to cooking fumes from rapeseed oil appeared to be at increased risk of lung cancer, and there was some evidence that fumes from linseed oil may have also contributed to the risk... - Tobacco use in adult long-term survivors of retinoblastomaMeredith C Foster
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, EPS 7044, 6120 Executive Boulevard, Rockville, MD 20852, USA
Cancer Epidemiol Biomarkers Prev 15:1464-8. 2006..Smoking did not account for the increased risk of lung cancer among hereditary Rb patients, and this may point to an enhanced sensitivity to the carcinogenic effects of tobacco. Adult survivors of Rb should be encouraged to stop smoking... - Menstrual and reproductive factors and risk of lung cancer among Chinese women, Eastern Gansu Province, 1994-1998Alina V Brenner
Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Rockville, EPS, Bethesda, MD 20892, USA
J Epidemiol 13:22-8. 2003..Odds ratios were lower for later ages at menarche (trend, P = 0.015) and later ages at menopause (trend, P = 0.074). Despite limitations, these findings suggest a possible role of hormones in the etiology of lung cancer in females... - Risk of lung cancer and residential radon in China: pooled results of two studiesJay H Lubin
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20892, USA
Int J Cancer 109:132-7. 2004.... - Second cancers among 104,760 survivors of cervical cancer: evaluation of long-term riskAnil K Chaturvedi
Viral Epidemiology Branch, Division of Cancer Epidemiology and Genetics, 6120 Executive Blvd, EPS 7072, Rockville, MD 20852, USA
J Natl Cancer Inst 99:1634-43. 2007.... 
Historical review of occupational exposures and cancer risks in medical radiation workersMartha S Linet
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892 7238, USA
Radiat Res 174:793-808. 2010....- Cancer screening practices of adult survivors of retinoblastoma at risk of second cancersVictoria Sheen
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland 20852, USA
Cancer 113:434-41. 2008..The aim of the current study was to investigate the pattern of cancer screening behavior in adult retinoblastoma survivors, who are at high risk of developing second cancers... - Occupational radiation doses to operators performing fluoroscopically-guided proceduresKwang Pyo Kim
Department of Nuclear Engineering, Kyung Hee University, Gyeonggi Do, Republic of Korea
Health Phys 103:80-99. 2012..Large variations in operator doses suggest that optimizing procedure protocols and proper use of protective devices and shields might reduce occupational radiation dose substantially... - Agreement between diary records of time spent outdoors and personal ultraviolet radiation dose measurementsGabriel Chodick
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, NCI, NIH, DHHS, Bethesda, MD, USA
Photochem Photobiol 84:713-8. 2008..g. driving) in which the participant is usually shaded from the sun. Our results demonstrated a significant correlation between diary records of time spent outdoors with objective personal UVR dose measurements... - Coronary heart disease after radiotherapy for peptic ulcer diseaseZhanat A Carr
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH/DHHS, 6120 Executive Boulevard, EPS 7038, Rockville, MD 20852, USA
Int J Radiat Oncol Biol Phys 61:842-50. 2005..CONCLUSION: The excess CHD risk in patients undergoing RT for peptic ulcer disease decades previously indicates the need for long-term follow-up for cardiovascular disease after chest RT... - Cancer mortality following radiotherapy for benign gynecologic disordersRitsu Sakata
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
Radiat Res 178:266-79. 2012.... - Occupational radiation doses to operators performing cardiac catheterization proceduresKwang Pyo Kim
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 7238, USA
Health Phys 94:211-27. 2008..Better standardization of dosimetric methods will facilitate future analyses aimed at determining how well medical radiation workers are being protected... - Analysis of retinoblastoma age incidence data using a fully stochastic cancer modelMark P Little
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, DHHS, NIH, Bethesda, MD 20852 7238, USA
Int J Cancer 130:631-40. 2012..The results strongly suggest that knockout of the two alleles of the RB1 gene is necessary and may be largely sufficient for the development of RB, in support of Knudson's two-hit hypothesis... - Uses of dosimetry in radiation epidemiologySteven L Simon
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
Radiat Res 166:125-7. 2006 - A reanalysis of curvature in the dose response for cancer and modifications by age at exposure following radiation therapy for benign diseaseMark P Little
Radiation Epidemiology Branch, National Cancer Institute, Rockville, Maryland 20852 7238, USA
Int J Radiat Oncol Biol Phys 85:451-9. 2013..To assess the shape of the dose response for various cancer endpoints and modifiers by age and time... - Feasibility of assessing the carcinogenicity of neutrons among neutron therapy patientsAlice J Sigurdson
Radiation Epidemiology Branch, National Cancer Institute, 6120 Executive Boulevard, Bethesda, Maryland 20892 7238, USA
Radiat Res 157:483-9. 2002.... - Malignant neoplasms after radiation therapy for peptic ulcerZhanat A Carr
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
Radiat Res 157:668-77. 2002..Our excess relative risk per gray estimate of 0.20 at doses <or=10 Gy (95% CI 0, 0.73) is consistent with the estimate of 0.24 (95% CI 0.10, 0.40) obtained from the LSS study with the linear model... - Agreement between contemporaneously recorded and subsequently recalled time spent outdoors: implications for environmental exposure studiesGabriel Chodick
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health DHHS, 6120 Executive Boulevard, Rockville, MD 20852, USA
Ann Epidemiol 17:106-11. 2007..The aim of the study is to evaluate the agreement between contemporaneously recorded and subsequently recalled time spent outdoors during 1 week among members of an occupational cohort... - International study of factors affecting human chromosome translocationsAlice J Sigurdson
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD, USA
Mutat Res 652:112-21. 2008..Our data provide stable estimates of background TF by age, gender, race, and smoking status and suggest an acceleration of chromosome damage above age 60 and among those with a history of smoking cigarettes... - Residential radon and lung cancer risk in a high-exposure area of Gansu Province, ChinaZuoyuan Wang
Laboratory of Industrial Hygiene, Ministry of Public Health, Beijing, China
Am J Epidemiol 155:554-64. 2002..Adjusting for exposure uncertainties increased estimates by 50%. Results support increased lung cancer risks with indoor radon exposures that may equal or exceed extrapolations based on miner data... - Risk factors for medullary thyroid carcinoma: a pooled analysisEva Negri
Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
Cancer Causes Control 13:365-72. 2002..To investigate risk factors for medullary thyroid cancer (MTC)...