Emily O Kistner

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Method for using complete and incomplete trios to identify genes related to a quantitative trait
    Emily O Kistner
    Biostatistics Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Genet Epidemiol 27:33-42. 2004
  2. ncbi request reprint A method for identifying genes related to a quantitative trait, incorporating multiple siblings and missing parents
    Emily O Kistner
    National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Genet Epidemiol 29:155-65. 2005
  3. pmc Genetic polymorphisms in transforming growth factor beta-1 (TGFB1) and childhood asthma and atopy
    Huiling Li
    Laboratory of Respiratory Biology, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Hum Genet 121:529-38. 2007
  4. ncbi request reprint A method for using incomplete triads to test maternally mediated genetic effects and parent-of-origin effects in relation to a quantitative trait
    Emily O Kistner
    Biostatistics Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA
    Am J Epidemiol 163:255-61. 2006
  5. pmc Genetic polymorphisms in arginase I and II and childhood asthma and atopy
    Huiling Li
    Laboratory of Respiratory Biology, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    J Allergy Clin Immunol 117:119-26. 2006
  6. ncbi request reprint A genome-wide association study identifies IL23R as an inflammatory bowel disease gene
    Richard H Duerr
    Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, School of Medicine, University of Pittsburgh, University of Pittsburgh Medical Center Presbyterian, Mezzanine Level, C Wing, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    Science 314:1461-3. 2006
  7. pmc Identification of genetic variants contributing to cisplatin-induced cytotoxicity by use of a genomewide approach
    R Stephanie Huang
    Department of Medicine, University of Chicago, Chicago, IL 60637, USA
    Am J Hum Genet 81:427-37. 2007
  8. doi request reprint Transmission disequilibrium testing of the chromosome 15q11-q13 region in autism
    Soo Jeong Kim
    Department of Psychiatry, College of Medicine, University of Florida, Gainesville, Florida, USA
    Am J Med Genet B Neuropsychiatr Genet 147:1116-25. 2008
  9. pmc Genetic variants contributing to daunorubicin-induced cytotoxicity
    R Stephanie Huang
    Department of Medicine, University of Chicago, Chicago, Illinois 60637, USA
    Cancer Res 68:3161-8. 2008
  10. pmc Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
    Jeffrey C Barrett
    Bioinformatics and Statistical Genetics, Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK
    Nat Genet 40:955-62. 2008

Collaborators

  • Håkon K Gjessing
  • Claire Infante-Rivard
  • C R Weinberg
  • Eduard Louis
  • R H Duerr
  • Carl A Anderson
  • Tariq Ahmad
  • JUDY CHO
  • Lon R Cardon
  • S A Fisher
  • Mark-S Silverberg
  • I Romieu
  • Dan L Nicolae
  • STEVEN BRANT
  • Jonathan Marchini
  • Jean Pierre Hugot
  • Severine Vermeire
  • S J London
  • R Stephanie Huang
  • Huiling Li
  • M Eileen Dolan
  • Shiwei Duan
  • Soo Jeong Kim
  • Jeffrey C Barrett
  • Matiana Ramirez-Aguilar
  • Juan Jose Sienra-Monge
  • Susan L Christian
  • Jack Satsangi
  • Miguel D Regueiro
  • Jilur Ghori
  • John Mansfield
  • Soma Das
  • Rhian Gwilliam
  • Shannon M Delaney
  • Denis Franchimont
  • Jacques Belaiche
  • Christine M Hartford
  • Mark Tremelling
  • Eric H Courchesne
  • Mark J Daly
  • Kent D Taylor
  • Nancy J Cox
  • M Michael Barmada
  • Camille W Brune
  • Miles Parkes
  • Simon Heath
  • Cynthia Sandor
  • Todd Green
  • Derek Jewell
  • Anne M Griffiths
  • Christopher G Mathew
  • A Hillary Steinhart
  • Ramnik J Xavier
  • Panos Deloukas
  • Natalie J Prescott
  • Ivo Gut
  • Jerome I Rotter
  • Michael T Murtha
  • Michel Georges
  • Donna L Fackenthal
  • John D Rioux
  • Diana Zelenika
  • Stephan R Targan
  • Martine De Vos
  • Themistocles Dassopoulos
  • Hazel Drummond
  • Edwin H Cook
  • Cecile Libioulle
  • Debby Laukens
  • Lisa Wu Datta
  • L Philip Schumm
  • Suzannah Bumpstead
  • Alain Bitton
  • Wasim K Bleibel
  • Myriam Mni
  • Paul Rutgeerts
  • Olivier Dewit
  • Clive M Onnie
  • Elaine Nimmo
  • Mark Lathrop
  • Sarah Hansoul
  • Andre Van Gossum
  • John E Blume
  • Hao Wu
  • Sunita J Shukla
  • Tyson A Clark
  • Anthony C Schweitzer
  • Blanca Estela del Rio-Navarro
  • Irma Carmen del Lara-Sánchez
  • Tina X Chen

Detail Information

Publications11

  1. ncbi request reprint Method for using complete and incomplete trios to identify genes related to a quantitative trait
    Emily O Kistner
    Biostatistics Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Genet Epidemiol 27:33-42. 2004
    ..In addition, missing parental genotype data can be accommodated through an expectation-maximization (EM) algorithm approach. The EM approach allows recovery of most of the lost power due to incomplete trios...
  2. ncbi request reprint A method for identifying genes related to a quantitative trait, incorporating multiple siblings and missing parents
    Emily O Kistner
    National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Genet Epidemiol 29:155-65. 2005
    ..We use simulations based on a population with admixture to compare our method to a popular non-parametric family-based association test (FBAT), testing the null of no association in the presence of linkage...
  3. pmc Genetic polymorphisms in transforming growth factor beta-1 (TGFB1) and childhood asthma and atopy
    Huiling Li
    Laboratory of Respiratory Biology, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Hum Genet 121:529-38. 2007
    ..77, 95% CI=1.22-2.57 for two copies). These three SNPs were also related to the degree of atopy. This largest study to date of genetic variation in TGFB1 and asthma and atopy adds to increasing evidence for a role in these disorders...
  4. ncbi request reprint A method for using incomplete triads to test maternally mediated genetic effects and parent-of-origin effects in relation to a quantitative trait
    Emily O Kistner
    Biostatistics Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA
    Am J Epidemiol 163:255-61. 2006
    ..Methods are illustrated with birth weight and gestational length, two quantitative outcomes for which data were collected in a Montreal, Canada, study of intrauterine growth restriction between May 1998 and June 2000...
  5. pmc Genetic polymorphisms in arginase I and II and childhood asthma and atopy
    Huiling Li
    Laboratory of Respiratory Biology, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    J Allergy Clin Immunol 117:119-26. 2006
    ..A recent microarray study implicated arginase I (ARG1) and arginase II (ARG2) in mouse allergic asthma models and human asthma...
  6. ncbi request reprint A genome-wide association study identifies IL23R as an inflammatory bowel disease gene
    Richard H Duerr
    Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, School of Medicine, University of Pittsburgh, University of Pittsburgh Medical Center Presbyterian, Mezzanine Level, C Wing, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    Science 314:1461-3. 2006
    ..These results and previous studies on the proinflammatory role of IL-23 prioritize this signaling pathway as a therapeutic target in inflammatory bowel disease...
  7. pmc Identification of genetic variants contributing to cisplatin-induced cytotoxicity by use of a genomewide approach
    R Stephanie Huang
    Department of Medicine, University of Chicago, Chicago, IL 60637, USA
    Am J Hum Genet 81:427-37. 2007
    ..Our whole-genome approach can be used to elucidate the expression of quantitative trait loci contributing to a wide range of cellular phenotypes...
  8. doi request reprint Transmission disequilibrium testing of the chromosome 15q11-q13 region in autism
    Soo Jeong Kim
    Department of Psychiatry, College of Medicine, University of Florida, Gainesville, Florida, USA
    Am J Med Genet B Neuropsychiatr Genet 147:1116-25. 2008
    ..Further investigation of the 15q11-q13 region with denser genotyping in a larger sample set may be necessary to determine whether this region confers risk to autism, indicated by association, or to specific autism phenotypes...
  9. pmc Genetic variants contributing to daunorubicin-induced cytotoxicity
    R Stephanie Huang
    Department of Medicine, University of Chicago, Chicago, Illinois 60637, USA
    Cancer Res 68:3161-8. 2008
    ..005 and P = 0.0008, respectively), and rs1551315 trends toward significance (P = 0.089). This unbiased method can be used to elucidate genetic variants contributing to a wide range of cellular phenotypes...
  10. pmc Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
    Jeffrey C Barrett
    Bioinformatics and Statistical Genetics, Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK
    Nat Genet 40:955-62. 2008
    ..The expanded molecular understanding of the basis of this disease offers promise for informed therapeutic development...
  11. pmc Genetic variants associated with carboplatin-induced cytotoxicity in cell lines derived from Africans
    R Stephanie Huang
    Department of Medicine, University of Chicago, 5841 South Maryland Avenue, Box MC2115, Chicago, IL 60637, USA
    Mol Cancer Ther 7:3038-46. 2008
    ..The identification of concentration specific genetic signatures allows for potential integration of pharmacokinetics, pharmacodynamics, and pharmacogenetics in tailoring chemotherapy...