Stephen Kingsmore

Summary

Affiliation: National Center for Genome Resources
Country: USA

Publications

  1. pmc Genome-wide association studies: progress and potential for drug discovery and development
    Stephen F Kingsmore
    National Center for Genome Resources, 2935 Rodeo Park Drive East, Santa Fe, New Mexico 87505, USA
    Nat Rev Drug Discov 7:221-30. 2008
  2. pmc Identification of diagnostic biomarkers for infection in premature neonates
    Stephen F Kingsmore
    National Center for Genome Resources, Santa Fe, New Mexico, 87505, USA
    Mol Cell Proteomics 7:1863-75. 2008
  3. pmc Genome-wide association studies: progress in identifying genetic biomarkers in common, complex diseases
    Stephen F Kingsmore
    National Center for Genome Resources, Santa Fe, NM 87505, U S A
    Biomark Insights 2:283-92. 2007
  4. pmc Genomic convergence analysis of schizophrenia: mRNA sequencing reveals altered synaptic vesicular transport in post-mortem cerebellum
    Joann Mudge
    National Center for Genome Resources, Santa Fe, NM, USA
    PLoS ONE 3:e3625. 2008
  5. pmc Sepsis progression and outcome: a dynamical model
    Sergey M Zuev
    DFA Capital Ltd AG, Norbertstr, 29, D 50670, Cologne, Germany
    Theor Biol Med Model 3:8. 2006
  6. pmc Multiplexed protein measurement: technologies and applications of protein and antibody arrays
    Stephen F Kingsmore
    National Center for Genome Resources, Santa Fe, New Mexico 87505, USA
    Nat Rev Drug Discov 5:310-20. 2006
  7. ncbi request reprint Multiplexed protein profiling on antibody-based microarrays by rolling circle amplification
    Stephen F Kingsmore
    Molecular Staging Inc, 300 George Street, New Haven, CT 06511, USA
    Curr Opin Biotechnol 14:74-81. 2003
  8. pmc Protein microarray analysis of disease activity in pediatric inflammatory bowel disease demonstrates elevated serum PLGF, IL-7, TGF-beta1, and IL-12p40 levels in Crohn's disease and ulcerative colitis patients in remission versus active disease
    Howard A Kader
    Pediatric Gastroenterology Associates, The Children s Hospital at Sinai, 2411 W Belvedere Avenue, Baltimore, MD 21215, USA
    Am J Gastroenterol 100:414-23. 2005
  9. ncbi request reprint Cerebral palsy is characterized by protein mediators in cord serum
    Tuula Kaukola
    Department of Pediatrics and Biocenter Oulu, University of Oulu, Oulu, Finland
    Ann Neurol 55:186-94. 2004
  10. pmc Unbiased whole-genome amplification directly from clinical samples
    Seiyu Hosono
    Molecular Staging, Inc, New Haven, Connecticut 06511, USA
    Genome Res 13:954-64. 2003

Research Grants

  1. Plasma Protein Biomarker-Based Diagnostics Of Outcome In Sepsis and CAP
    Stephen Kingsmore; Fiscal Year: 2007
  2. Biomarker Chip for Osteoarthritis
    Stephen Kingsmore; Fiscal Year: 2002

Collaborators

  • Rosalinda C Roberts
  • M Hallman
  • Howard A Kader
  • Qin Fu
  • Velizar T Tchernev
  • Barry Schweitzer
  • Seiyu Hosono
  • Frank B Dean
  • Joann Mudge
  • Sergey M Zuev
  • Tuula Kaukola
  • Michael Egholm
  • Zhenyu Sun
  • A Fawad Faruqi
  • Xiaohong Wu
  • Yuefen Du
  • Roger S Lasken
  • Jing Du
  • Lar C Mader
  • Stanton Martin
  • Wendy Czika
  • Meredith Garcia
  • Selene M Virk
  • Jim J Huntley
  • Ingrid E Lindquist
  • M Kathy Myers
  • C Forrest Black
  • Gregory D May
  • William D Beavis
  • Lu Zhang
  • Faye D Schilkey
  • Jennifer C Van Velkinburgh
  • Neil A Miller
  • Sat Kirpal Khalsa
  • Shujun Luo
  • Irina Khrebtukova
  • Gary P Schroth
  • Andrew D Farmer
  • Russell D Wolfinger
  • Nora I Perrone-Bizzozero
  • Richard Harlan
  • Sharon Lewis
  • Ryan W Kim
  • Victoria Ambriz-Griffith
  • Ray J Langley
  • John P Utsey
  • Damian D G Gessler
  • Leena Vainionpaa
  • Ebenezer Satyaraj
  • Brian G Grimwade
  • Helena Pihko
  • Outi Tammela
  • Tuula AƤrimaa
  • Pentti Koskela
  • Dhavalkumar D Patel
  • Weiping Shao
  • Mark Velleca
  • A Madan Kumar
  • Minjuan Wang
  • Patricia Bray-Ward
  • Mark Driscoll
  • Quiping Shu
  • Loic Giot
  • Jonathan M Rothberg
  • Scott Roberts
  • Brian Grimwade
  • Linhua Fang
  • Ying Li
  • Jason Christiansen
  • Isabelle Laroche
  • Krishnan Nandabalan
  • Qiuling Zong
  • John C Detter
  • Wanmin Song
  • Frederick S Southwick
  • Margaret R Wallace
  • Zhimin Zhou
  • Vishnu S Mishra
  • Traci A Mansfield

Detail Information

Publications14

  1. pmc Genome-wide association studies: progress and potential for drug discovery and development
    Stephen F Kingsmore
    National Center for Genome Resources, 2935 Rodeo Park Drive East, Santa Fe, New Mexico 87505, USA
    Nat Rev Drug Discov 7:221-30. 2008
    ....
  2. pmc Identification of diagnostic biomarkers for infection in premature neonates
    Stephen F Kingsmore
    National Center for Genome Resources, Santa Fe, New Mexico, 87505, USA
    Mol Cell Proteomics 7:1863-75. 2008
    ..Multiplexed immunoassays of serum cytokines may have clinical utility as an adjunct for rapid diagnosis of infection and differentiation of etiologic agent in neonates with clinical decompensation...
  3. pmc Genome-wide association studies: progress in identifying genetic biomarkers in common, complex diseases
    Stephen F Kingsmore
    National Center for Genome Resources, Santa Fe, NM 87505, U S A
    Biomark Insights 2:283-92. 2007
    ..In general, it appears that complex diseases are associated with many common polymorphisms, implying profound genetic heterogeneity between affected individuals...
  4. pmc Genomic convergence analysis of schizophrenia: mRNA sequencing reveals altered synaptic vesicular transport in post-mortem cerebellum
    Joann Mudge
    National Center for Genome Resources, Santa Fe, NM, USA
    PLoS ONE 3:e3625. 2008
    ..Twenty three genes with altered expression and involvement in presynaptic vesicular transport, Golgi function and GABAergic neurotransmission define a unifying molecular hypothesis for dysfunction in cerebellar cortex in SCZ...
  5. pmc Sepsis progression and outcome: a dynamical model
    Sergey M Zuev
    DFA Capital Ltd AG, Norbertstr, 29, D 50670, Cologne, Germany
    Theor Biol Med Model 3:8. 2006
    ..There exists a need for dynamical models of sepsis progression, based upon basic physiologic principles, which could eventually guide hourly treatment decisions...
  6. pmc Multiplexed protein measurement: technologies and applications of protein and antibody arrays
    Stephen F Kingsmore
    National Center for Genome Resources, Santa Fe, New Mexico 87505, USA
    Nat Rev Drug Discov 5:310-20. 2006
    ..This review describes current and emerging multiplexed protein measurement technologies and their applications, and discusses the remaining challenges in this field...
  7. ncbi request reprint Multiplexed protein profiling on antibody-based microarrays by rolling circle amplification
    Stephen F Kingsmore
    Molecular Staging Inc, 300 George Street, New Haven, CT 06511, USA
    Curr Opin Biotechnol 14:74-81. 2003
    ..When allied with multivariate statistical analysis, RCA protein chips have the potential to identify multiplexed biomarker classifiers for disease diagnosis and drug response...
  8. pmc Protein microarray analysis of disease activity in pediatric inflammatory bowel disease demonstrates elevated serum PLGF, IL-7, TGF-beta1, and IL-12p40 levels in Crohn's disease and ulcerative colitis patients in remission versus active disease
    Howard A Kader
    Pediatric Gastroenterology Associates, The Children s Hospital at Sinai, 2411 W Belvedere Avenue, Baltimore, MD 21215, USA
    Am J Gastroenterol 100:414-23. 2005
    ....
  9. ncbi request reprint Cerebral palsy is characterized by protein mediators in cord serum
    Tuula Kaukola
    Department of Pediatrics and Biocenter Oulu, University of Oulu, Oulu, Finland
    Ann Neurol 55:186-94. 2004
    ..The cytokine patterns at birth differ between premature and term infants who develop CP...
  10. pmc Unbiased whole-genome amplification directly from clinical samples
    Seiyu Hosono
    Molecular Staging, Inc, New Haven, Connecticut 06511, USA
    Genome Res 13:954-64. 2003
    ..The low amplification bias of MDA represents a dramatic technical improvement in the ability to amplify a whole genome compared with older, PCR-based methods...
  11. pmc The Chediak-Higashi protein interacts with SNARE complex and signal transduction proteins
    Velizar T Tchernev
    CuraGen Corporation, New Haven, CT 06511, USA
    Mol Med 8:56-64. 2002
    ..The goal of this study was to identify proteins that interact with LYST as a first step in understanding how LYST modulates lysosomal exocytosis...
  12. pmc Comprehensive human genome amplification using multiple displacement amplification
    Frank B Dean
    Molecular Staging, Inc, 300 George Street, Suite 701, New Haven, CT 06511, USA
    Proc Natl Acad Sci U S A 99:5261-6. 2002
    ..MDA-based WGA is a simple and reliable method that could have significant implications for genetic studies, forensics, diagnostics, and long-term sample storage...
  13. pmc Multiplexed protein profiling on microarrays by rolling-circle amplification
    Barry Schweitzer
    Molecular Staging, Inc, Suite 701, 300 George Street, New Haven, CT 06511, USA
    Nat Biotechnol 20:359-65. 2002
    ..Because microarrays can accommodate approximately 1,000 sandwich immunoassays of this type, a relatively small number of RCA microarrays seem to offer a tractable approach for proteomic surveys...
  14. ncbi request reprint Measuring proteins on microarrays
    Barry Schweitzer
    Molecular Staging Inc, 300 George Street, Suite 701, New Haven, CT 06511, USA
    Curr Opin Biotechnol 13:14-9. 2002
    ....

Research Grants3

  1. Plasma Protein Biomarker-Based Diagnostics Of Outcome In Sepsis and CAP
    Stephen Kingsmore; Fiscal Year: 2007
    ....
  2. Biomarker Chip for Osteoarthritis
    Stephen Kingsmore; Fiscal Year: 2002
    ..We also will identify other reagents as potentially useful biomarkers for OA with the aim of designing an OA chip. ..