Genomes and Genes
Benjamin L Kidder
Affiliation: National Institutes of Health
- HDAC1 regulates pluripotency and lineage specific transcriptional networks in embryonic and trophoblast stem cellsBenjamin L Kidder
EMD Serono Research Institute, Billerica, MA 01821, USA
Nucleic Acids Res 40:2925-39. 2012..By mapping HDAC1 targets on a global scale, our results describe further insight into epigenetic mechanisms of ES and TS cells self-renewal...
- ChIP-Seq: technical considerations for obtaining high-quality dataBenjamin L Kidder
Laboratory of Molecular Immunology, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA
Nat Immunol 12:918-22. 2011..Here we describe several technical aspects of the ChIP-Seq assay that diminish bias and background noise and allow the consistent generation of high-quality data...
- Examination of transcriptional networks reveals an important role for TCFAP2C, SMARCA4, and EOMES in trophoblast stem cell maintenanceBenjamin L Kidder
EMD Serono Research Institute, Inc, Rockland, MA 02370, USA
Genome Res 20:458-72. 2010..Through genome-wide mapping and global expression analysis of five TF target genes, our data provide a comprehensive analysis of transcriptional networks that regulate TS cell self-renewal...
- Gene expression profiles of mouse submandibular gland development: FGFR1 regulates branching morphogenesis in vitro through BMP- and FGF-dependent mechanismsMatthew P Hoffman
Craniofacial Developmental Biology and Regeneration Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, 30 Convent Drive, MSC 4370, Bethesda, MD 20892 4370, USA
Development 129:5767-78. 2002..Taken together, our results suggest specific FGFs and BMPs play reciprocal roles in regulating branching morphogenesis and FGFR1 signaling plays a central role by regulating both FGF and BMP expression...
- SWI/SNF-Brg1 regulates self-renewal and occupies core pluripotency-related genes in embryonic stem cellsBenjamin L Kidder
EMD Serono Research Institute, Inc, Rockland, Massachusetts, USA
Stem Cells 27:317-28. 2009..Moreover, Brg1 co-occupied a subset of Oct4, Sox2, Nanog, and PcG protein target genes. These results demonstrate an important role for Brg1 in regulating self-renewal and pluripotency in ES cells...