Pavel P Khil

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi Crystal structure of Escherichia coli protein ybgI, a toroidal structure with a dinuclear metal site
    Jane E Ladner
    Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute and the National Institute of Standards and Technology, 9600 Gudelsky Drive, Rockville, MD 20850, USA
    BMC Struct Biol 3:7. 2003
  2. ncbi Crystal structure of the Escherichia coli YjiA protein suggests a GTP-dependent regulatory function
    Pavel P Khil
    Genetics and Biochemistry Branch, NIDDK, National Institutes of Health, Bethesda, Maryland 20892, USA
    Proteins 54:371-4. 2004
  3. ncbi Crystal structure of the YgfZ protein from Escherichia coli suggests a folate-dependent regulatory role in one-carbon metabolism
    Alexey Teplyakov
    Center for Advanced Research in Biotechnology, 9600 Gudelsky Drive, Rockville, MD 20850, USA
    J Bacteriol 186:7134-40. 2004
  4. ncbi Crystal structure of the Escherichia coli Tas protein, an NADP(H)-dependent aldo-keto reductase
    Galina Obmolova
    Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute and the National Institute of Standards and Technology, Rockville, Maryland 20850, USA
    Proteins 53:323-5. 2003
  5. ncbi Crystal structure of the YchF protein reveals binding sites for GTP and nucleic acid
    Alexey Teplyakov
    Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute and the National Institute of Standards and Technology, Rockville, Maryland 20850, USA
    J Bacteriol 185:4031-7. 2003
  6. ncbi Crystal structure of the Escherichia coli YcdX protein reveals a trinuclear zinc active site
    Alexey Teplyakov
    Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute and the National Institute of Standards and Technology, Rockville, Maryland 20850, USA
    Proteins 51:315-8. 2003
  7. ncbi Crystal structure of the YajQ protein from Haemophilus influenzae reveals a tandem of RNP-like domains
    Alexey Teplyakov
    Center for Advanced Research in Biotechnology of the University of Maryland Biotechnology Institute and the National Institute of Standards and Technology, 9600 Gudelsky Drive, Rockville, MD 20850, USA
    J Struct Funct Genomics 4:1-9. 2003
  8. ncbi Assisting functional assignment for hypothetical Heamophilus influenzae gene products through structural genomics
    Gary L Gilliland
    Center for Advanced Research in Biotechnology of the University of Maryland Biotechnology Institute and the National Institute of Standards and Technology, 9600 Gudelsky Drive, Rockville, MD 20850, USA
    Curr Drug Targets Infect Disord 2:339-53. 2002
  9. ncbi Crystal structure of the YffB protein from Pseudomonas aeruginosa suggests a glutathione-dependent thiol reductase function
    Alexey Teplyakov
    Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute, 9600 Gudelsky Drive, Rockville, MD 20850, USA
    BMC Struct Biol 4:5. 2004
  10. ncbi Crystal structure of the YjeE protein from Haemophilus influenzae: a putative Atpase involved in cell wall synthesis
    Alexey Teplyakov
    Center for Advanced Research in Biotechnology of the University of Maryland Biotechnology Institute, Rockville, Maryland 20850, USA
    Proteins 48:220-6. 2002

Collaborators

Detail Information

Publications10

  1. ncbi Crystal structure of Escherichia coli protein ybgI, a toroidal structure with a dinuclear metal site
    Jane E Ladner
    Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute and the National Institute of Standards and Technology, 9600 Gudelsky Drive, Rockville, MD 20850, USA
    BMC Struct Biol 3:7. 2003
    ..The protein encoded by the gene ybgI was chosen as a target for a structural genomics project emphasizing the relation of protein structure to function...
  2. ncbi Crystal structure of the Escherichia coli YjiA protein suggests a GTP-dependent regulatory function
    Pavel P Khil
    Genetics and Biochemistry Branch, NIDDK, National Institutes of Health, Bethesda, Maryland 20892, USA
    Proteins 54:371-4. 2004
  3. ncbi Crystal structure of the YgfZ protein from Escherichia coli suggests a folate-dependent regulatory role in one-carbon metabolism
    Alexey Teplyakov
    Center for Advanced Research in Biotechnology, 9600 Gudelsky Drive, Rockville, MD 20850, USA
    J Bacteriol 186:7134-40. 2004
    ....
  4. ncbi Crystal structure of the Escherichia coli Tas protein, an NADP(H)-dependent aldo-keto reductase
    Galina Obmolova
    Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute and the National Institute of Standards and Technology, Rockville, Maryland 20850, USA
    Proteins 53:323-5. 2003
  5. ncbi Crystal structure of the YchF protein reveals binding sites for GTP and nucleic acid
    Alexey Teplyakov
    Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute and the National Institute of Standards and Technology, Rockville, Maryland 20850, USA
    J Bacteriol 185:4031-7. 2003
    ..Taken together with other experimental data and genomic analysis, these results suggest that YchF may be part of a nucleoprotein complex and may function as a GTP-dependent translation factor...
  6. ncbi Crystal structure of the Escherichia coli YcdX protein reveals a trinuclear zinc active site
    Alexey Teplyakov
    Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute and the National Institute of Standards and Technology, Rockville, Maryland 20850, USA
    Proteins 51:315-8. 2003
  7. ncbi Crystal structure of the YajQ protein from Haemophilus influenzae reveals a tandem of RNP-like domains
    Alexey Teplyakov
    Center for Advanced Research in Biotechnology of the University of Maryland Biotechnology Institute and the National Institute of Standards and Technology, 9600 Gudelsky Drive, Rockville, MD 20850, USA
    J Struct Funct Genomics 4:1-9. 2003
    ..This structural motif is a characteristic feature of many RNA-binding proteins. The tetrameric structure observed in the crystal suggests a possibility of binding two stretches of double-stranded nucleic acid...
  8. ncbi Assisting functional assignment for hypothetical Heamophilus influenzae gene products through structural genomics
    Gary L Gilliland
    Center for Advanced Research in Biotechnology of the University of Maryland Biotechnology Institute and the National Institute of Standards and Technology, 9600 Gudelsky Drive, Rockville, MD 20850, USA
    Curr Drug Targets Infect Disord 2:339-53. 2002
    ..In addition to aiding in functional assignment, this effort is identifying a number of possible new targets for drug development...
  9. ncbi Crystal structure of the YffB protein from Pseudomonas aeruginosa suggests a glutathione-dependent thiol reductase function
    Alexey Teplyakov
    Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute, 9600 Gudelsky Drive, Rockville, MD 20850, USA
    BMC Struct Biol 4:5. 2004
    ..The crystal structure determination of YffB was undertaken as part of a structural genomics effort in order to assist with the functional assignment of the protein...
  10. ncbi Crystal structure of the YjeE protein from Haemophilus influenzae: a putative Atpase involved in cell wall synthesis
    Alexey Teplyakov
    Center for Advanced Research in Biotechnology of the University of Maryland Biotechnology Institute, Rockville, Maryland 20850, USA
    Proteins 48:220-6. 2002
    ..The distribution of conserved residues suggests that the protein may work as a "molecular switch" triggered by ATP hydrolysis. The phylogenetic pattern of YjeE suggests its involvement in cell wall biosynthesis...