Research Topics
| P KellmanSummaryAffiliation: National Institutes of Health Country: USA Publications
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Publications
Cardiac imaging techniques for physicians: late enhancementPeter Kellman
National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA
J Magn Reson Imaging 36:529-42. 2012..The aim of this review will be to describe the current state of the art and to provide a guide to various clinical protocols that are commonly used...
High spatial and temporal resolution cardiac cine MRI from retrospective reconstruction of data acquired in real time using motion correction and resortingPeter Kellman
Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, DHHS, Bethesda, Maryland 20892 1061, USA
Magn Reson Med 62:1557-64. 2009..s.). Motion-corrected averaging of real-time acquired cardiac images provides a means of attaining high-quality cine images with many of the benefits of real-time imaging, such as free-breathing acquisition and tolerance to arrhythmias...- Artifact suppression in imaging of myocardial infarction using B1-weighted phased-array combined phase-sensitive inversion recoveryPeter Kellman
Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, DHHS, Bethesda, Maryland 20892 1061, USA
Magn Reson Med 51:408-12. 2004..Example images are shown that illustrate the suppression of CSF ghost artifacts by the use of B1-weighted phased-array combining of multiple receiver coils... - Phased array ghost eliminationPeter Kellman
Laboratory of Cardiac Energetics, National Institutes of Health, National Heart, Lung and Blood Institute, Bethesda, MD 20892 1061, USA
NMR Biomed 19:352-61. 2006..The more general scheme may be used to modulate each EPI ghost image to a separate temporal frequency as described in this paper... - Image reconstruction in SNR units: a general method for SNR measurementPeter Kellman
Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, DHHS, Bethesda, Maryland 20892 1061, USA
Magn Reson Med 54:1439-47. 2005..The procedure includes scaling for noise equivalent bandwidth of digital receivers, FFTs and associated window functions (raw data filters), and array combining... - T2* measurement during first-pass contrast-enhanced cardiac perfusion imagingPeter Kellman
Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, DHHS, Bethesda, Maryland 20892 1061, USA
Magn Reson Med 56:1132-4. 2006..For single-dose Gd-DTPA (0.1 mmol/kg at 5 ml/s), the LV blood pool T(2) (*) had a mean value of 9 ms (N = 10) at peak enhancement. Distortion of the AIF due to T(2) (*) signal intensity loss will be less than 10% using TE = 0.6 ms... 
Imaging sequences for first pass perfusion --a reviewPeter Kellman
Laboratory of Cardiac Energetics, Department of Health and Human Services, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892 1061, USA
J Cardiovasc Magn Reson 9:525-37. 2007..Understanding the interaction between the pulse sequence parameters and resulting image quality is important for improving myocardial perfusion imaging...- T2-prepared SSFP improves diagnostic confidence in edema imaging in acute myocardial infarction compared to turbo spin echoPeter Kellman
Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892 1061, USA
Magn Reson Med 57:891-7. 2007..Free-breathing T2 prepared SSFP provides T2-weighted images of acute MI with fewer artifacts and better diagnostic accuracy than conventional dark-blood TSE... - Fully automatic, retrospective enhancement of real-time acquired cardiac cine MR images using image-based navigators and respiratory motion-corrected averagingPeter Kellman
Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
Magn Reson Med 59:771-8. 2008..Motion-corrected averaging of real-time acquired cardiac images provides a means of attaining high-quality cine images with many of the benefits of real-time imaging, such as free-breathing acquisition and tolerance to arrhythmias... - Multiecho dixon fat and water separation method for detecting fibrofatty infiltration in the myocardiumPeter Kellman
Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, U S Department of Health and Human Services, Bethesda, Maryland 20892 1061, USA
Magn Reson Med 61:215-21. 2009..The multiecho Dixon method for fat and water separation provides a sensitive means of detecting intramyocardial fat with positive signal contrast... - Extended coverage first-pass perfusion imaging using slice-interleaved TSENSEP Kellman
Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, DHHS, Bethesda, Maryland 20892 1061, USA
Magn Reson Med 51:200-4. 2004..Experiments in normal subjects (N=6) were performed to assess signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) values... - Automatic in-plane rotation for doubly-oblique cardiac imagingPeter Kellman
Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
J Magn Reson Imaging 18:612-5. 2003..To develop and test a method for automatically calculating the in-plane rotation for doubly-oblique slice geometry in order to minimize wrap artifacts for a given FOV... - Phased array ghost elimination (PAGE) for segmented SSFP imaging with interrupted steady-statePeter Kellman
Laboratory of Cardiac Energetics, National Institutes of Health, National Heart, Lung and Blood Institute, Bethesda, Maryland 20892 1061, USA
Magn Reson Med 48:1076-80. 2002..PAGE was demonstrated for cardiac cine SSFP imaging with interrupted steady-state using a simple alpha/2 magnetization preparation and storage scheme and a spatial tagging preparation... - Adaptive sensitivity encoding incorporating temporal filtering (TSENSE)P Kellman
Laboratory of Cardiac Energetics, National Institutes of Health, National Heart, Lung and Blood Institute, Bethesda, Maryland 20892 1061, USA
Magn Reson Med 45:846-52. 2001..Experimental results that demonstrate the adaptive spatiotemporal filtering method (adaptive TSENSE) with acceleration factor R = 2, for real-time nonbreath-held cardiac MR imaging during exercise induced stress are presented... - Low-latency temporal filter design for real-time MRI using UNFOLDP Kellman
Laboratory of Cardiac Energetics, National Institutes of Health, National Heart, Lung, and Blood Institute, Bethesda, Maryland 20892 1061, USA
Magn Reson Med 44:933-9. 2000..e., monitoring needle insertion and injection of a drug with contrast enhancement properties. Proof-of-concept was demonstrated by injecting a contrast agent. In both applications the UNFOLD technique was used to double the frame rate... - Method for functional MRI mapping of nonlinear responsePeter Kellman
Laboratory of Cardiac Energetics, NHLBI, National Institutes of Health, Bethesda, MD 20892, USA
Neuroimage 19:190-9. 2003..The results indicate that BOLD fMRI can probe fast neuronal nonlinearities... - Ghost artifact cancellation using phased array processingP Kellman
Laboratory of Cardiac Energetics, National Institutes of Health, National Heart, Lung and Blood Institute, Bethesda, Maryland 20892 1061, USA
Magn Reson Med 46:335-43. 2001..Experimental results demonstrate the cancellation for both phantom as well as cardiac imaging examples... - Phase-sensitive inversion recovery for detecting myocardial infarction using gadolinium-delayed hyperenhancementPeter Kellman
Laboratory of Cardiac Energetics, National Institutes of Health, National Heart, Lung and Blood Institute, Bethesda, Maryland 20892-1061, USA
Magn Reson Med 47:372-83. 2002..Phase-sensitive detection also has the advantage of decreasing the sensitivity to changes in tissue T(1) with increasing delay from contrast agent injection... - Late gadolinium-enhancement cardiac magnetic resonance identifies postinfarction myocardial fibrosis and the border zone at the near cellular level in ex vivo rat heartErik B Schelbert
Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892 1061, USA
Circ Cardiovasc Imaging 3:743-52. 2010.... - Motion-corrected free-breathing delayed enhancement imaging of myocardial infarctionPeter Kellman
Laboratory of Cardiac Energetics, National Heart, Lung, and Blood Institute, National Institutes of Health, DHHS, 10 Center Drive, MSC-1061, Building 10, Room B1D416, Bethesda, MD 20892, USA
Magn Reson Med 53:194-200. 2005..In this study, motion correction was implemented using image registration postprocessing rather than navigator correction of individual frames. Navigator techniques may be incorporated as well... - Motion corrected free-breathing delayed-enhancement imaging of myocardial infarction using nonrigid registrationMaria J Ledesma Carbayo
Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, DHHS, Bethesda, Maryland 20892 1061, USA
J Magn Reson Imaging 26:184-90. 2007..To develop and test an automatic free-breathing, delayed enhancement imaging method with improved image signal-to-noise ratio (SNR)... - Quantitative myocardial infarction on delayed enhancement MRI. Part I: Animal validation of an automated feature analysis and combined thresholding infarct sizing algorithmLi-Yueh Hsu
Laboratory of Cardiac Energetics, National Heart Lung and Blood Institute, National Institutes of Health/DHHS, 10 Center Drive, Bethesda, MD 20892, USA
J Magn Reson Imaging 23:298-308. 2006..007). CONCLUSION: The FACT algorithm accurately measured MI size on delayed enhancement MR imaging in vivo and ex vivo. The FACT algorithm was also more accurate than human manual contouring and simple intensity thresholding approaches... - Multi-contrast delayed enhancement provides improved contrast between myocardial infarction and blood poolPeter Kellman
Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, DHHS, Bethesda, Maryland 20892-1061, USA
J Magn Reson Imaging 22:605-13. 2005..MCODE should improve both the detection and accurate sizing of MI... - Gadolinium delayed enhancement cardiovascular magnetic resonance correlates with clinical measures of myocardial infarctionW Patricia Ingkanisorn
National Heart, Lung, and Blood Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892-1061, USA
J Am Coll Cardiol 43:2253-9. 2004..003). CONCLUSION: In humans imaged shortly after acute MI, gadolinium delayed enhancement acute CMR infarct size correlates with acute and chronic indices of infarct size but will appear to diminish in size on follow-up... - Magnetic resonance imaging delineates the ischemic area at risk and myocardial salvage in patients with acute myocardial infarctionColin Berry
Department of Health and Human Services, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892 1061, USA
Circ Cardiovasc Imaging 3:527-35. 2010..The area at risk (AAR) is a key determinant of myocardial infarction (MI) size. We investigated whether magnetic resonance imaging (MRI) measurement of AAR would be correlated with an angiographic AAR risk score in patients with acute MI... - Nonlinear myocardial signal intensity correction improves quantification of contrast-enhanced first-pass MR perfusion in humansLi Yueh Hsu
Laboratory of Cardiac Energetics, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892 1061, USA
J Magn Reson Imaging 27:793-801. 2008..To study the nonlinearity of myocardial signal intensity and gadolinium contrast concentration during first-pass perfusion MRI, and to compare quantitative perfusion estimates using nonlinear myocardial signal intensity correction... - HTGRAPPA: real-time B1-weighted image domain TGRAPPA reconstructionHaris Saybasili
National Institutes of Health, National Heart, Lung, and Blood Institute, DHHS, Bethesda, Maryland 20892 1061, USA
Magn Reson Med 61:1425-33. 2009..The weight-set coefficients were computed in an adaptive manner with updates linked to changes in the imaging scan plane. In this implementation, reconstruction speed is not dependent on acceleration rate or GRAPPA kernel size... - ACUT2E TSE-SSFP: a hybrid method for T2-weighted imaging of edema in the heartAnthony H Aletras
Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health DHHS, 10 Center Drive, Bethesda, MD 20892, USA
Magn Reson Med 59:229-35. 2008..Imperfect blood suppression, present in all animals on some TSE images, was a problem eliminated by TSE-SSFP and T2-prepared SSFP... - RT-GROG: parallelized self-calibrating GROG for real-time MRIHaris Saybasili
Translational Medicine Branch, National Institutes of Health National Heart, Lung and Blood Institute NHLBI, Department of Health and Human Services DHHS, Bethesda, Maryland 20892 1061, USA
Magn Reson Med 64:306-12. 2010..On a 32-coil dataset of size 128 x 64, reconstruction performance is 14.5 frames per second (fps), while the data acquisition is 6.6 fps... - Single heartbeat cardiac tagging for the evaluation of transient phenomenaDaniel A Herzka
Department of Biomedical Engineering, Johns Hopkins University School of Medicine Baltimore, Maryland 20892 1061, USA
Magn Reson Med 54:1455-64. 2005..Images acquired during the Valsalva maneuver demonstrated apparent beat-to-beat variability, visible both in the images and as changing strain patterns and ventricular volumes... - Multishot EPI-SSFP in the heartDaniel A Herzka
Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland 20892 1061, USA
Magn Reson Med 47:655-64. 2002..The increased TR of multishot EPI-SSFP led to a reduced specific absorption rate (SAR) for a fixed RF flip angle, and allowed the use of a larger flip angle without increasing the SAR above the FDA-approved limits... - Parallelized hybrid TGRAPPA reconstruction for real-time interactive MRIHaris Saybasili
NHLBI, National Institutes of Health, DHHS, Bethesda, MD, USA
Med Image Comput Comput Assist Interv 11:163-70. 2008..The computation was parallelized and implemented on a general purpose multi-core architecture. Reconstruction speeds of 65-70 frames per second were achieved with a matrix of 192 x 144 with 15 coils... - Short communication: Subcellular motion compensation for minimally invasive microscopy, in vivo: evidence for oxygen gradients in resting muscleJames L Schroeder
Laboratory of Cardiac Energetics, National Heart, Lung, and Blood Institute, NIH, 10 Center Drive, Bethesda, MD 20892, USA
Circ Res 106:1129-33. 2010..A primary limitation of optical microscopy in vivo is tissue motion, which prevents physiological time course observations or image averaging... - Real-time blood flow imaging using autocalibrated spiral sensitivity encodingReza Nezafat
Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland 20892 1061, USA
Magn Reson Med 54:1557-61. 2005..Real-time experiments were performed to measure blood velocity in the ascending aorta and aortic valve, and during a Valsalva maneuver. The results demonstrate the potential of this technique for real-time flow imaging... - Real-time, Interactive MRI for cardiovascular interventionsElliot R McVeigh
Laboratory of Cardiac Energetics, National Heart, Lung, and Blood Institute, National Institutes of Health, Building 10, Room B1D416, Bethesda, MD 20892-106, USA
Acad Radiol 12:1121-7. 2005 - Real-time accelerated interactive MRI with adaptive TSENSE and UNFOLDMichael A Guttman
Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
Magn Reson Med 50:315-21. 2003..For imaging with a combination of surface and interventional coils, a hybrid reconstruction approach is proposed whereby UNFOLD is used for the interventional coils, and TSENSE with or without UNFOLD is used for the surface coils... - Application of sensitivity-encoded echo-planar imaging for blood oxygen level-dependent functional brain imagingJacco A de Zwart
Advanced MRI, Laboratory of Functional and Molecular Imaging, NINDS, National Institutes of Health, Bethesda, Maryland 20892 1065, USA
Magn Reson Med 48:1011-20. 2002.... - Temporal dynamics of the BOLD fMRI impulse responseJacco A de Zwart
Laboratory of Functional and Molecular Imaging, NINDS, National Institutes of Health, Bethesda, MD 20892 1065, USA
Neuroimage 24:667-77. 2005..These results are consistent with a substantial macrovascular dispersive contribution to BOLD IR in humans, and furthermore suggest that neurovascular coupling is a relatively rapid process, with a resolution below 2.3 s FWHM... - Quantitative myocardial infarction on delayed enhancement MRI. Part II: Clinical application of an automated feature analysis and combined thresholding infarct sizing algorithmLi-Yueh Hsu
Laboratory of Cardiac Energetics, National Heart Lung and Blood Institute, National Institutes of Health/DHHS, 10 Center Drive, Bethesda, MD 20892, USA
J Magn Reson Imaging 23:309-14. 2006..002 and P < 0.001). CONCLUSION: Clinically relevant overestimation of MI can occur in visual interpretation and in human manual contouring, particularly with respect to extent of infarction on a regional basis... - Quantitative myocardial perfusion analysis with a dual-bolus contrast-enhanced first-pass MRI technique in humansLi-Yueh Hsu
Laboratory of Cardiac Energetics, National Heart Lung and Blood Institute, National Institutes of Health/DHHS, 10 Center Drive, Bethesda, MD 20892, USA
J Magn Reson Imaging 23:315-22. 2006..CONCLUSION: Rest and stress MBF (mL/min/g) and MPR estimated by dual-bolus perfusion MRI fit within published ranges. Semiquantitative methods (SLP and CER) significantly underestimated MPR... - Electromechanical analysis of infarct border zone in chronic myocardial infarctionHiroshi Ashikaga
Laboratory of Cardiac Energetics, NHLBI, NIH, 10 Center Dr, MSC 1061, Bldg 10, B1D416, Bethesda, MD 20892 1061, USA
Am J Physiol Heart Circ Physiol 289:H1099-105. 2005..This indicates that impaired function in the border zone is not contributed by electrical factors but results from mechanical interaction between ischemic and normal myocardium... - PCATMIP: enhancing signal intensity in diffusion-weighted magnetic resonance imagingV M Pai
Laboratory of Cardiac Energetics, NHLBI, National Institutes of Health, Bethesda, Maryland 20892 1061, USA
Magn Reson Med 65:1611-9. 2011.... - Hunting for neuronal currents: absence of rapid MRI signal changes during visual-evoked responseRenxin Chu
Advanced MRI Section, LMFI, NINDS, National Institutes of Health, Building 10, Room B1D-118, 9000 Rockville Pike, Bethesda, MD 20892-1065, USA
Neuroimage 23:1059-67. 2004.... - Detection of myocardial capillary orientation with intravascular iron-oxide nanoparticles in spin-echo MRIAlexandre Vignaud
Laboratory of Cardiac Energetics, Division of Intramural Research, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892-1061, USA
Magn Reson Med 55:725-30. 2006..Preliminary results also demonstrate the feasibility of this method for in vivo application to rodent imaging... - Reduction of gradient acoustic noise in MRI using SENSE-EPIJacco A de Zwart
Advanced MRI, Laboratory of Functional and Molecular Imaging, NINDS, National Institutes of Health, Bethesda, Maryland, USA
Neuroimage 16:1151-5. 2002..5 dB(A) for rate-2 and rate-3 SENSE, respectively. BOLD fMRI experiments, using visually paced finger-tapping paradigms, showed no detrimental effect of the acoustic noise reduction strategy on temporal noise levels and t scores... - Fluctuation analysis of mitochondrial NADH fluorescence signals in confocal and two-photon microscopy images of living cardiac myocytesK Blinova
Laboratory of Cardiac Energetics, National Heart Lung and Blood Institute, National Institutes of Health, Department of Health and Human Services, Bethesda MD 20892, USA
J Microsc 213:70-5. 2004.... - Design of a SENSE-optimized high-sensitivity MRI receive coil for brain imagingJacco A de Zwart
Advanced MRI, Laboratory of Functional and Molecular Imaging, NINDS, National Institutes of Health, Bethesda, Maryland 20892-1065, USA
Magn Reson Med 47:1218-27. 2002..7-fold improvement of the SNR averaged over the brain compared to a conventional quadrature birdcage receive coil and an average geometrical noise amplification factor (g-value) of 1.06 and 1.38 for rate-2 and rate-3 SENSE, respectively... - Assessment of regional systolic and diastolic dysfunction in familial hypertrophic cardiomyopathy using MR taggingDaniel B Ennis
Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Magn Reson Med 50:638-42. 2003..03). The combination of CSPAMM and CAPTOR allows regional indices of myocardial function to be quantified throughout the cardiac cycle. This technique reveals regional differences in systolic and diastolic impairment in FHC patients... - Preliminary investigation of respiratory self-gating for free-breathing segmented cine MRIAndrew C Larson
Department of Biomedical Engineering, Northwestern University, Chicago, IL 60611, USA
Magn Reson Med 53:159-68. 2005..Because of the difficulties associated with breath-holding, the respiratory self-gating technique represents an important practical advance for cardiac MRI. , Inc... - Dynamic autocalibrated parallel imaging using temporal GRAPPA (TGRAPPA)Felix A Breuer
University of Wurzburg, Department of Physics, EP 5, Am Hubland, 97074 Wurzburg, Germany
Magn Reson Med 53:981-5. 2005..This method may update coil sensitivity estimates frame by frame, thereby tracking changes in relative coil sensitivities that may occur during the data acquisition... - Direct comparison of myocardial perfusion cardiovascular magnetic resonance sequences with parallel acquisitionJonathan C Lyne
Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, London, UK
J Magn Reson Imaging 26:1444-51. 2007..To directly compare the three main myocardial perfusion cardiovascular magnetic resonance (CMR) sequences incorporating parallel acquisition methods... - Improved cine displacement-encoded MRI using balanced steady-state free precession and time-adaptive sensitivity encoding parallel imaging at 3 TDaniel Kim
Department of Radiology, New York University, New York, NY 10016, USA
NMR Biomed 20:591-601. 2007..The combined implementation of b-SSFP imaging, 3T imaging, echo-combination image reconstruction, and TSENSE parallel imaging can be used to incrementally improve the cine displacement-encoded MRI pulse sequence... - Semiautomated segmentation of myocardial contours for fast strain analysis in cine displacement-encoded MRITing Chen
Department of Radiology, New York University, 650 First Ave, New York, NY 10016, USA
IEEE Trans Med Imaging 27:1084-94. 2008..This relatively accurate semiautomated segmentation method can be used to significantly increase the throughput of strain analysis of cine displacement-encoded MR images for clinical applications...