Jennifer M Keller

Summary

Affiliation: National Oceanic and Atmospheric Administration
Country: USA

Publications

  1. pmc Effects of organochlorine contaminants on loggerhead sea turtle immunity: comparison of a correlative field study and in vitro exposure experiments
    Jennifer M Keller
    Nicholas School of the Environment and Earth Sciences, Coastal Systems Science and Policy, and Integrated Toxicology Program, Duke University, Beaufort, North Carolina, USA
    Environ Health Perspect 114:70-76. 2006
  2. doi request reprint Forty-seven days of decay does not change persistent organic pollutant levels in loggerhead sea turtle eggs
    Jennifer M Keller
    Chemical Sciences Division, National Institute of Standards and Technology, Hollings Marine Laboratory, Charleston, South Carolina, USA
    Environ Toxicol Chem 32:747-56. 2013
  3. doi request reprint Perfluoroalkyl contaminants in plasma of five sea turtle species: comparisons in concentration and potential health risks
    Jennifer M Keller
    Analytical Chemistry Division, Hollings Marine Laboratory, National Institute of Standards and Technology, Charleston, South Carolina, USA
    Environ Toxicol Chem 31:1223-30. 2012
  4. doi request reprint Comparison of five extraction methods for measuring PCBs, PBDEs, organochlorine pesticides, and lipid content in serum
    Jennifer M Keller
    National Institute of Standards and Technology, Analytical Chemistry Division, Hollings Marine Laboratory, 331 Ft Johnson Rd, Charleston, SC 29412, USA
    Anal Bioanal Chem 393:747-60. 2009
  5. ncbi request reprint Perfluorinated compounds in the plasma of loggerhead and Kemp's ridley sea turtles from the southeastern coast of the United States
    Jennifer M Keller
    Hollings Marine Laboratory, National Institute of Standards and Technology, Charleston, South Carolina 29412, USA
    Environ Sci Technol 39:9101-8. 2005
  6. ncbi request reprint Mitogen-induced lymphocyte proliferation in loggerhead sea turtles: comparison of methods and effects of gender, plasma testosterone concentration, and body condition on immunity
    Jennifer M Keller
    Coastal Systems Science and Policy, and Integrated Toxicology Program, Nicholas School of the Environment and Earth Sciences, Duke University, 135 Duke Marine Lab Road, Beaufort, NC 28516, USA
    Vet Immunol Immunopathol 103:269-81. 2005
  7. ncbi request reprint Organochlorine contaminants in sea turtles: correlations between whole blood and fat
    Jennifer M Keller
    Duke University, Integrated Toxicology Program and Nicholas School of the Environment and Earth Sciences, Division of Coastal Systems Science and Policy, Beaufort, North Carolina 28516, USA
    Environ Toxicol Chem 23:726-38. 2004
  8. pmc Associations between organochlorine contaminant concentrations and clinical health parameters in loggerhead sea turtles from North Carolina, USA
    Jennifer M Keller
    Duke University, Integrated Toxicology Program and Nicholas School of the Environment Coastal Systems Science and Policy, Beaufort, North Carolina, USA
    Environ Health Perspect 112:1074-9. 2004
  9. doi request reprint Determination of perfluorinated alkyl acid concentrations in human serum and milk standard reference materials
    Jennifer M Keller
    Analytical Chemistry Division, Hollings Marine Laboratory, National Institute of Standards and Technology, Charleston, SC 29412, USA
    Anal Bioanal Chem 397:439-51. 2010
  10. ncbi request reprint Comparison of mercury burdens in chronically debilitated and healthy loggerhead sea turtles (Caretta caretta)
    Rusty D Day
    National Institute of Standards and Technology, Hollings Marine Laboratory, 331 Fort Johnson Rd, Charleston, South Carolina 29412, USA
    J Wildl Dis 46:111-7. 2010

Detail Information

Publications27

  1. pmc Effects of organochlorine contaminants on loggerhead sea turtle immunity: comparison of a correlative field study and in vitro exposure experiments
    Jennifer M Keller
    Nicholas School of the Environment and Earth Sciences, Coastal Systems Science and Policy, and Integrated Toxicology Program, Duke University, Beaufort, North Carolina, USA
    Environ Health Perspect 114:70-76. 2006
    ..The similarities between the in vitro experiments and the correlative field study suggest that OC exposure modulates immunity in loggerhead turtles...
  2. doi request reprint Forty-seven days of decay does not change persistent organic pollutant levels in loggerhead sea turtle eggs
    Jennifer M Keller
    Chemical Sciences Division, National Institute of Standards and Technology, Hollings Marine Laboratory, Charleston, South Carolina, USA
    Environ Toxicol Chem 32:747-56. 2013
    ..05), which may have implications for hatchling fitness. The present study suggests that unhatched eggs can be used for POP-monitoring projects...
  3. doi request reprint Perfluoroalkyl contaminants in plasma of five sea turtle species: comparisons in concentration and potential health risks
    Jennifer M Keller
    Analytical Chemistry Division, Hollings Marine Laboratory, National Institute of Standards and Technology, Charleston, South Carolina, USA
    Environ Toxicol Chem 31:1223-30. 2012
    ..These baseline concentrations and the preliminary EMOS exercise provide a better understanding of the potential health risks of PFCs for conservation managers to protect these threatened and endangered species...
  4. doi request reprint Comparison of five extraction methods for measuring PCBs, PBDEs, organochlorine pesticides, and lipid content in serum
    Jennifer M Keller
    National Institute of Standards and Technology, Analytical Chemistry Division, Hollings Marine Laboratory, 331 Ft Johnson Rd, Charleston, SC 29412, USA
    Anal Bioanal Chem 393:747-60. 2009
    ..This study offers valid, novel extraction alternatives beyond traditional methods (e.g., LLE) for blood contaminant measurements...
  5. ncbi request reprint Perfluorinated compounds in the plasma of loggerhead and Kemp's ridley sea turtles from the southeastern coast of the United States
    Jennifer M Keller
    Hollings Marine Laboratory, National Institute of Standards and Technology, Charleston, South Carolina 29412, USA
    Environ Sci Technol 39:9101-8. 2005
    ..018; carapace length used as a proxy for age), and (3) higher in turtles captured toward the north (p = 0.006). These findings suggest that bioaccumulation of PFCs in sea turtles is influenced by species, age, and habitat...
  6. ncbi request reprint Mitogen-induced lymphocyte proliferation in loggerhead sea turtles: comparison of methods and effects of gender, plasma testosterone concentration, and body condition on immunity
    Jennifer M Keller
    Coastal Systems Science and Policy, and Integrated Toxicology Program, Nicholas School of the Environment and Earth Sciences, Duke University, 135 Duke Marine Lab Road, Beaufort, NC 28516, USA
    Vet Immunol Immunopathol 103:269-81. 2005
    ..Lastly, using these optimized methods, we investigated the effect of gender, plasma testosterone concentration, and body condition on LP in loggerhead turtles and found that none of the parameters largely influenced LP...
  7. ncbi request reprint Organochlorine contaminants in sea turtles: correlations between whole blood and fat
    Jennifer M Keller
    Duke University, Integrated Toxicology Program and Nicholas School of the Environment and Earth Sciences, Division of Coastal Systems Science and Policy, Beaufort, North Carolina 28516, USA
    Environ Toxicol Chem 23:726-38. 2004
    ..Therefore, caution should be used when monitoring spatial or temporal trends, as OC levels may increase in the blood following mobilization of fat stores, such as during long migrations, breeding, or disease events...
  8. pmc Associations between organochlorine contaminant concentrations and clinical health parameters in loggerhead sea turtles from North Carolina, USA
    Jennifer M Keller
    Duke University, Integrated Toxicology Program and Nicholas School of the Environment Coastal Systems Science and Policy, Beaufort, North Carolina, USA
    Environ Health Perspect 112:1074-9. 2004
    ..These correlations suggest that OC contaminants may be affecting the health of loggerhead sea turtles even though sea turtles accumulate lower concentrations of OCs compared with other wildlife...
  9. doi request reprint Determination of perfluorinated alkyl acid concentrations in human serum and milk standard reference materials
    Jennifer M Keller
    Analytical Chemistry Division, Hollings Marine Laboratory, National Institute of Standards and Technology, Charleston, SC 29412, USA
    Anal Bioanal Chem 397:439-51. 2010
    ..linear isomers. The concentrations in these SRMs are similar to the present-day average concentrations measured in human serum and milk, resulting in representative and useful control materials for PFAA human monitoring studies...
  10. ncbi request reprint Comparison of mercury burdens in chronically debilitated and healthy loggerhead sea turtles (Caretta caretta)
    Rusty D Day
    National Institute of Standards and Technology, Hollings Marine Laboratory, 331 Fort Johnson Rd, Charleston, South Carolina 29412, USA
    J Wildl Dis 46:111-7. 2010
    ..These findings suggest that Hg toxicity does not play a role in the debilitated loggerhead condition observed in the southeastern United States...
  11. ncbi request reprint Certification of SRM 1589a PCBs, pesticides, PBDEs, and dioxins/furans in human serum
    Michele M Schantz
    Analytical Chemistry Division, National Institute of Standards and Technology, Gaithersburg, MD 20899, USA
    Anal Bioanal Chem 389:1201-8. 2007
    ....
  12. doi request reprint Milk and serum standard reference materials for monitoring organic contaminants in human samples
    Michele M Schantz
    Analytical Chemistry Division, National Institute of Standards and Technology NIST, Gaithersburg, MD 20899, USA
    Anal Bioanal Chem 405:1203-11. 2013
    ..This agreement suggests that there were no significant biases existing among the multiple methods used for analysis...
  13. doi request reprint Determination of perfluorinated alkyl acid concentrations in biological standard reference materials
    Jessica L Reiner
    Analytical Chemistry Division, National Institute of Standards and Technology, Gaithersburg, MD 20899 8392, USA
    Anal Bioanal Chem 404:2683-92. 2012
    ..Measurements in SRMs show an array of PFAAs, with perfluorooctane sulfonate (PFOS) being the most frequently detected. Reference and information values are reported for PFAAs measured in these biological SRMs...
  14. doi request reprint Suppression of humoral immunity in mice following exposure to perfluorooctane sulfonate
    Margie M Peden-Adams
    Department of Pediatrics, Medical, University of South Carolina, Charleston, South Carolina 29412, USA
    Toxicol Sci 104:144-54. 2008
    ..Overall, this study provides a profile of PFOS immunotoxicity showing effects at levels reported in humans and identifies the B-cells as a potential target...
  15. doi request reprint Monitoring persistent organic pollutants in leatherback turtles (Dermochelys coriacea) confirms maternal transfer
    Kelly R Stewart
    Duke University Center for Marine Conservation, Nicholas School of the Environment, Duke University Marine Laboratory, 135 Duke Marine Lab Road, Beaufort, NC 28516, USA
    Mar Pollut Bull 62:1396-409. 2011
    ..Concentrations were lower than those shown to have acute toxic effects in other aquatic reptiles, but may have sub-lethal effects on hatchling body condition and health...
  16. ncbi request reprint Standard reference materials (SRMs) for determination of organic contaminants in environmental samples
    Stephen A Wise
    Analytical Chemistry Division, National Institute of Standards and Technology, Gaithersburg, MD 20899, USA
    Anal Bioanal Chem 386:1153-90. 2006
    ....
  17. doi request reprint Persistent organic pollutants in blood plasma of satellite-tracked adult male loggerhead sea turtles (Caretta caretta)
    Jared M Ragland
    Grice Marine Laboratory, College of Charleston, Charleston, South Carolina, USA
    Environ Toxicol Chem 30:1549-56. 2011
    ..The present study is the first to examine POPs in the rarely studied adult male sea turtle and to couple contaminant measurements with satellite tracking...
  18. doi request reprint Geographical variation of persistent organic pollutants in eggs of threatened loggerhead sea turtles (Caretta caretta) from southeastern United States
    Juan Jose Alava
    National Oceanic and Atmospheric Administration, Charleston, South Carolina, USA
    Environ Toxicol Chem 30:1677-88. 2011
    ..These findings are important to managers assessing threats among different stocks or subpopulations of this threatened species...
  19. doi request reprint Temporal and spatial trends of perfluorinated compounds in juvenile loggerhead sea turtles (Caretta caretta) along the East Coast of the United States
    Steven G O'Connell
    National Institute of Standards and Technology, Analytical Chemistry Division, Hollings Marine Laboratory, Charleston, South Carolina 29412, USA
    Environ Sci Technol 44:5202-9. 2010
    ....
  20. doi request reprint Spatial and temporal trends of perfluorinated compounds in Beluga Whales (Delphinapterus leucas) from Alaska
    Jessica L Reiner
    National Institute of Standards and Technology, Analytical Chemistry Division, Hollings Marine Laboratory, 331 Ft Johnson Road, Charleston, South Carolina 29412, United States
    Environ Sci Technol 45:8129-36. 2011
    ..05). These observations suggest the accumulation of PFCs in belugas is influenced by year, location, sex, and length...
  21. doi request reprint Spatial and temporal trends of persistent organic pollutants and mercury in beluga whales (Delphinapterus leucas) from Alaska
    Jennifer Hoguet
    National Institute of Standards and Technology, Chemical Sciences Division, Hollings Marine Laboratory, 331 Fort Johnson Road, Charleston, SC 29412, USA
    Sci Total Environ 449:285-94. 2013
    ..Sex and length also significantly influenced some concentrations, and these findings are discussed...
  22. doi request reprint Organohalogen contaminants in blood of Kemp's ridley (Lepidochelys kempii) and green sea turtles (Chelonia mydas) from the Gulf of Mexico
    Robert F Swarthout
    National Institute of Standards and Technology, Analytical Chemistry Division, Hollings Marine Laboratory, Charleston, SC 29412, USA
    Chemosphere 78:731-41. 2010
    ..kempii. These data help establish baseline contaminant concentrations in live L. kempii and C. mydas...
  23. doi request reprint Determination of perfluorinated compounds in human plasma and serum Standard Reference Materials using independent analytical methods
    Jessica L Reiner
    Analytical Chemistry Division, National Institute of Standards and Technology, Gaithersburg, MD 20899 8392, USA
    Anal Bioanal Chem 401:2899-907. 2011
    ..Other PFCs were also detected in SRM 1950 and are reported. SRM 1950 can be used as a control material for human biomonitoring studies and as an aid to develop new measurement methods...
  24. doi request reprint Immunotoxicity of perfluorinated compounds: recent developments
    Jamie C DeWitt
    Department of Pharmacology and Toxicology, Brody School of Medicine, East Carolina University, Greenville, North Carolina 27834, USA
    Toxicol Pathol 40:300-11. 2012
    ..This review contains brief descriptions of current and recently published work exploring immunomodulation by PFOA, PFOS, and other PFCs in rodent models, alternative laboratory models, and wildlife...
  25. ncbi request reprint Determination of polybrominated diphenyl ethers in indoor dust standard reference materials
    Heather M Stapleton
    Analytical Chemistry Division, National Institute of Standards and Technology, Gaithersburg, MD 20899, USA
    Anal Bioanal Chem 384:791-800. 2006
    ..These SRMs are the first reference materials with certified concentrations for PBDEs, which will aid in validating future measurements of PBDEs in house dust and other similar matrices...
  26. ncbi request reprint Effects of organochlorine compounds on cytochrome P450 aromatase activity in an immortal sea turtle cell line
    Jennifer M Keller
    Marine Laboratory, Duke University, 135 Duke Marine Lab Road, Beaufort, NC 28516, USA
    Mar Environ Res 58:347-51. 2004
    ..Based on these results, this in vitro model can be useful in examining the endocrine effects of EACs in sea turtles...
  27. ncbi request reprint Loggerhead sea turtle (Caretta caretta) egg yolk concentrations of persistent organic pollutants and lipid increase during the last stage of embryonic development
    Juan Jose Alava
    School of the Environment, University of South Carolina, 702G Byrnes Building, Columbia, SC 29208, USA
    Sci Total Environ 367:170-81. 2006
    ..More research is required to investigate geographical trends of contaminant concentrations and potential health effects (i.e., abnormalities) caused by these contaminants on sea turtle development...