Mary Kearney

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Analysis of 454 sequencing error rate, error sources, and artifact recombination for detection of Low-frequency drug resistance mutations in HIV-1 DNA
    Wei Shao
    Advanced Biomedical Computing Center, SAIC Frederick, Frederick National Laboratory for Cancer Research, PO Box B, Frederick, MD, USA
    Retrovirology 10:18. 2013
  2. pmc Multiple sources of contamination in samples from patients reported to have XMRV infection
    Mary F Kearney
    HIV Drug Resistance Program, National Cancer Institute, Frederick, Maryland, United States of America
    PLoS ONE 7:e30889. 2012
  3. pmc RT-SHIV subpopulation dynamics in infected macaques during anti-HIV therapy
    Wei Shao
    Advanced Biomedical Computing Center, SAIC Frederick, Inc, National Cancer Institute at Frederick, Frederick, MD, USA
    Retrovirology 6:101. 2009
  4. pmc Genetic diversity of simian immunodeficiency virus encoding HIV-1 reverse transcriptase persists in macaques despite antiretroviral therapy
    Mary Kearney
    HIV Drug Resistance Program, National Cancer Institute at Frederick, 1050 Boyles Street, Building 535, Room 109, Frederick, MD 21702 1201, USA
    J Virol 85:1067-76. 2011
  5. pmc Patterns of Human Immunodeficiency Virus type 1 recombination ex vivo provide evidence for coadaptation of distant sites, resulting in purifying selection for intersubtype recombinants during replication
    Andrea Galli
    HIV Drug Resistance Program, National Cancer Institute Frederick, Frederick, Maryland 21702, USA
    J Virol 84:7651-61. 2010
  6. pmc HIV Populations Are Large and Accumulate High Genetic Diversity in a Nonlinear Fashion
    Frank Maldarelli
    HIV Drug Resistance Program, NCI Frederick, NIH, Frederick, Maryland, USA
    J Virol 87:10313-23. 2013
  7. pmc Frequent polymorphism at drug resistance sites in HIV-1 protease and reverse transcriptase
    Mary Kearney
    HIV Drug Resistance Program, National Cancer Institute, National Institutes of Health, Frederick, Maryland 21702 1201, USA
    AIDS 22:497-501. 2008
  8. pmc Suppression of viremia and evolution of human immunodeficiency virus type 1 drug resistance in a macaque model for antiretroviral therapy
    Zandrea Ambrose
    HIV Drug Resistance Program, National Cancer Institute, Building 535, Room 123, Frederick, MD 21702, USA
    J Virol 81:12145-55. 2007
  9. pmc Single cell analysis of lymph node tissue from HIV-1 infected patients reveals that the majority of CD4+ T-cells contain one HIV-1 DNA molecule
    Lina Josefsson
    Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Solna, Sweden
    PLoS Pathog 9:e1003432. 2013
  10. ncbi request reprint Selection and persistence of non-nucleoside reverse transcriptase inhibitor-resistant HIV-1 in patients starting and stopping non-nucleoside therapy
    Sarah Palmer
    HIV Drug Resistance Program, National Cancer Institute, National Institutes of Health, Frederick, Maryland 21702 1201, USA
    AIDS 20:701-10. 2006

Collaborators

Detail Information

Publications10

  1. pmc Analysis of 454 sequencing error rate, error sources, and artifact recombination for detection of Low-frequency drug resistance mutations in HIV-1 DNA
    Wei Shao
    Advanced Biomedical Computing Center, SAIC Frederick, Frederick National Laboratory for Cancer Research, PO Box B, Frederick, MD, USA
    Retrovirology 10:18. 2013
    ..We evaluated the performance of 454 sequencing for characterizing HIV populations with defined allele frequencies...
  2. pmc Multiple sources of contamination in samples from patients reported to have XMRV infection
    Mary F Kearney
    HIV Drug Resistance Program, National Cancer Institute, Frederick, Maryland, United States of America
    PLoS ONE 7:e30889. 2012
    ....
  3. pmc RT-SHIV subpopulation dynamics in infected macaques during anti-HIV therapy
    Wei Shao
    Advanced Biomedical Computing Center, SAIC Frederick, Inc, National Cancer Institute at Frederick, Frederick, MD, USA
    Retrovirology 6:101. 2009
    ..Bioinformatics tools were constructed to trace individual genomes from the beginning of infection to the end of the treatment...
  4. pmc Genetic diversity of simian immunodeficiency virus encoding HIV-1 reverse transcriptase persists in macaques despite antiretroviral therapy
    Mary Kearney
    HIV Drug Resistance Program, National Cancer Institute at Frederick, 1050 Boyles Street, Building 535, Room 109, Frederick, MD 21702 1201, USA
    J Virol 85:1067-76. 2011
    ....
  5. pmc Patterns of Human Immunodeficiency Virus type 1 recombination ex vivo provide evidence for coadaptation of distant sites, resulting in purifying selection for intersubtype recombinants during replication
    Andrea Galli
    HIV Drug Resistance Program, National Cancer Institute Frederick, Frederick, Maryland 21702, USA
    J Virol 84:7651-61. 2010
    ..Therefore, the ability of the recombinants to replicate is the major barrier for many of these viruses...
  6. pmc HIV Populations Are Large and Accumulate High Genetic Diversity in a Nonlinear Fashion
    Frank Maldarelli
    HIV Drug Resistance Program, NCI Frederick, NIH, Frederick, Maryland, USA
    J Virol 87:10313-23. 2013
    ....
  7. pmc Frequent polymorphism at drug resistance sites in HIV-1 protease and reverse transcriptase
    Mary Kearney
    HIV Drug Resistance Program, National Cancer Institute, National Institutes of Health, Frederick, Maryland 21702 1201, USA
    AIDS 22:497-501. 2008
    ..Failure of antiretroviral therapy may result from the selection of pre-existing, drug-resistant HIV-1 variants, but the frequency and type of such variants have not been defined...
  8. pmc Suppression of viremia and evolution of human immunodeficiency virus type 1 drug resistance in a macaque model for antiretroviral therapy
    Zandrea Ambrose
    HIV Drug Resistance Program, National Cancer Institute, Building 535, Room 123, Frederick, MD 21702, USA
    J Virol 81:12145-55. 2007
    ..By contrast, ART effectively suppressed RT-SHIV in 5/6 animals. These data indicate that suboptimal therapy facilitates HIV-1 drug resistance and suggest that this model can be used to investigate persisting viral reservoirs...
  9. pmc Single cell analysis of lymph node tissue from HIV-1 infected patients reveals that the majority of CD4+ T-cells contain one HIV-1 DNA molecule
    Lina Josefsson
    Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Solna, Sweden
    PLoS Pathog 9:e1003432. 2013
    ....
  10. ncbi request reprint Selection and persistence of non-nucleoside reverse transcriptase inhibitor-resistant HIV-1 in patients starting and stopping non-nucleoside therapy
    Sarah Palmer
    HIV Drug Resistance Program, National Cancer Institute, National Institutes of Health, Frederick, Maryland 21702 1201, USA
    AIDS 20:701-10. 2006
    ..Understanding the selection and decay of drug-resistant HIV-1 variants is important for designing optimal antiretroviral therapy...