Research Topics
Genomes and Genes
Species | Wolfgang KastenmullerSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
A spatially-organized multicellular innate immune response in lymph nodes limits systemic pathogen spreadWolfgang Kastenmuller
Lymphocyte Biology Section, Laboratory of Systems Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
Cell 150:1235-48. 2012....
Regulatory T cells selectively control CD8+ T cell effector pool size via IL-2 restrictionWolfgang Kastenmuller
Laboratory of Systems Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
J Immunol 187:3186-97. 2011....
Compartmentalized control of skin immunity by resident commensalsShruti Naik
Mucosal Immunology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA
Science 337:1115-9. 2012..These findings underscore the importance of the microbiota as a distinctive feature of tissue compartmentalization, and provide insight into mechanisms of immune system regulation by resident commensal niches in health and disease...
Cutting edge: mucosal application of a lyophilized viral vector vaccine confers systemic and protective immunity toward intracellular pathogensWolfgang Kastenmuller
Institute of Virology, Helmholtz Center Munich, Munich, Germany
J Immunol 182:2573-7. 2009..These data clearly demonstrate the potency of a simple needle-free vaccination, combining the advantages of mucosal application with the stability and efficiency of lyophilized MVA...
Histo-cytometry: a method for highly multiplex quantitative tissue imaging analysis applied to dendritic cell subset microanatomy in lymph nodesMichael Y Gerner
Lymphocyte Biology Section, Laboratory of Systems Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
Immunity 37:364-76. 2012..Here, we employ histo-cytometry to describe the spatial segregation of resident and migratory dendritic cell subsets into specialized microanatomical domains, suggesting an unexpected LN demarcation into discrete functional compartments...
The in situ dynamics of dendritic cell interactionsWolfgang Kastenmuller
Lymphocyte Biology Section, Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892 1892, USA
Eur J Immunol 40:2103-6. 2010..In this Viewpoint, we discuss the insights generated by direct visualization of DC-T-cell interactions and the controversies/unanswered questions that need to be addressed in future work...
