Rose Marie Karlsson

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Galanin as a modulator of anxiety and depression and a therapeutic target for affective disease
    R M Karlsson
    Laboratory of Clinical and Translational Science, National Institute of Alcoholism and Alcohol Abuse, National Institutes of Health, Bethesda, MD 20892, U S A
    Amino Acids 31:231-9. 2006
  2. ncbi request reprint The neuropeptide Y Y1 receptor subtype is necessary for the anxiolytic-like effects of neuropeptide Y, but not the antidepressant-like effects of fluoxetine, in mice
    Rose Marie Karlsson
    Laboratory of Clinical and Translational Studies, NIH, National Institute of Alcohol Abuse and Alcoholism, NIH, 10 Center Drive, 1 15330, Bethesda, MD 20892 1375, USA
    Psychopharmacology (Berl) 195:547-57. 2008
  3. pmc Assessment of glutamate transporter GLAST (EAAT1)-deficient mice for phenotypes relevant to the negative and executive/cognitive symptoms of schizophrenia
    Rose Marie Karlsson
    Laboratory of Clinical and Translational Studies, National Institute on Alcohol Abuse and Alcoholism, NIH, 10 Center Drive, 10 Room 1E 5330, Bethesda, MD 20892, USA
    Neuropsychopharmacology 34:1578-89. 2009
  4. pmc Loss of glial glutamate and aspartate transporter (excitatory amino acid transporter 1) causes locomotor hyperactivity and exaggerated responses to psychotomimetics: rescue by haloperidol and metabotropic glutamate 2/3 agonist
    Rose Marie Karlsson
    Laboratory for Clinical and Translational Studies, National Institute on Alcoholism and Alcohol Abuse, National Institutes of Health, Bethesda, Maryland 20892, USA
    Biol Psychiatry 64:810-4. 2008
  5. pmc Effects of adolescent fluoxetine treatment on fear-, anxiety- or stress-related behaviors in C57BL/6J or BALB/cJ mice
    Maxine Norcross
    Section on Behavioral Science and Genetics, Laboratory for Integrative Neuroscience, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, 5625 Fishers Lane, Room 2N09, Rockville, MD, 20852 9411, USA
    Psychopharmacology (Berl) 200:413-24. 2008
  6. ncbi request reprint Anxiolytic-like actions of centrally-administered neuropeptide Y, but not galanin, in C57BL/6J mice
    Rose Marie Karlsson
    Division of Psychiatry, Neurotec, Karolinska Institute, Stockholm Laboratory of Clinical Science, NIAAA, NIH, Bethesda, MD, USA
    Pharmacol Biochem Behav 80:427-36. 2005
  7. pmc Impaired fear extinction learning and cortico-amygdala circuit abnormalities in a common genetic mouse strain
    Kathryn Hefner
    Section on Behavioral Science and Genetics, Laboratory for Integrative Neuroscience, National Institute on Alcoholism and Alcohol Abuse, National Institutes of Health, Rockville, Maryland 20852, USA
    J Neurosci 28:8074-85. 2008
  8. ncbi request reprint Short-term and long-term effects of postnatal exposure to an adult male in C57BL/6J mice
    Kathryn Hefner
    Section on Behavioral Science and Genetics, Laboratory for Integrative Neuroscience, National Institute on Alcohol Abuse and Alcoholism, NIH, Rockville, MD 20852 9411, USA
    Behav Brain Res 182:344-8. 2007
  9. pmc Desipramine potentiation of the acute depressant effects of ethanol: modulation by alpha2-adrenoreceptors and stress
    Janel M Boyce-Rustay
    Laboratory for Integrative Neuroscience, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Rockville, MD, USA
    Neuropharmacology 55:803-11. 2008
  10. pmc Reduced alcohol intake and reward associated with impaired endocannabinoid signaling in mice with a deletion of the glutamate transporter GLAST
    Rose Marie Karlsson
    Laboratory of Clinical and Translational Studies, National Institute on Alcoholism and Alcohol Abuse, NIH, 10 Center Drive, 1 5330, Bethesda, MD 20892 1108, USA
    Neuropharmacology 63:181-9. 2012

Collaborators

Detail Information

Publications16

  1. ncbi request reprint Galanin as a modulator of anxiety and depression and a therapeutic target for affective disease
    R M Karlsson
    Laboratory of Clinical and Translational Science, National Institute of Alcoholism and Alcohol Abuse, National Institutes of Health, Bethesda, MD 20892, U S A
    Amino Acids 31:231-9. 2006
    ....
  2. ncbi request reprint The neuropeptide Y Y1 receptor subtype is necessary for the anxiolytic-like effects of neuropeptide Y, but not the antidepressant-like effects of fluoxetine, in mice
    Rose Marie Karlsson
    Laboratory of Clinical and Translational Studies, NIH, National Institute of Alcohol Abuse and Alcoholism, NIH, 10 Center Drive, 1 15330, Bethesda, MD 20892 1375, USA
    Psychopharmacology (Berl) 195:547-57. 2008
    ..Neuropeptide Y (NPY) is implicated in the pathophysiology of affective illness. Multiple receptor subtypes (Y1R, Y2R, and Y5R) have been suggested to contribute to NPY's effects on rodent anxiety and depression-related behaviors...
  3. pmc Assessment of glutamate transporter GLAST (EAAT1)-deficient mice for phenotypes relevant to the negative and executive/cognitive symptoms of schizophrenia
    Rose Marie Karlsson
    Laboratory of Clinical and Translational Studies, National Institute on Alcohol Abuse and Alcoholism, NIH, 10 Center Drive, 10 Room 1E 5330, Bethesda, MD 20892, USA
    Neuropsychopharmacology 34:1578-89. 2009
    ..These findings demonstrate that gene deletion of GLAST produces select phenotypic abnormalities related to the negative and cognitive symptoms of schizophrenia...
  4. pmc Loss of glial glutamate and aspartate transporter (excitatory amino acid transporter 1) causes locomotor hyperactivity and exaggerated responses to psychotomimetics: rescue by haloperidol and metabotropic glutamate 2/3 agonist
    Rose Marie Karlsson
    Laboratory for Clinical and Translational Studies, National Institute on Alcoholism and Alcohol Abuse, National Institutes of Health, Bethesda, Maryland 20892, USA
    Biol Psychiatry 64:810-4. 2008
    ....
  5. pmc Effects of adolescent fluoxetine treatment on fear-, anxiety- or stress-related behaviors in C57BL/6J or BALB/cJ mice
    Maxine Norcross
    Section on Behavioral Science and Genetics, Laboratory for Integrative Neuroscience, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, 5625 Fishers Lane, Room 2N09, Rockville, MD, 20852 9411, USA
    Psychopharmacology (Berl) 200:413-24. 2008
    ..Adverse effects of treatment with serotonin reuptake inhibitor (SRI) antidepressants have been reported in human adolescents. However, the long-term effects of chronic SRI treatment during adolescence in rodents remain unclear...
  6. ncbi request reprint Anxiolytic-like actions of centrally-administered neuropeptide Y, but not galanin, in C57BL/6J mice
    Rose Marie Karlsson
    Division of Psychiatry, Neurotec, Karolinska Institute, Stockholm Laboratory of Clinical Science, NIAAA, NIH, Bethesda, MD, USA
    Pharmacol Biochem Behav 80:427-36. 2005
    ..These findings provide a basis for future studies of mice with targeted gene mutations, directed at delineating the anatomical regions and receptor subtypes mediating the effects of NPY and GAL on emotion...
  7. pmc Impaired fear extinction learning and cortico-amygdala circuit abnormalities in a common genetic mouse strain
    Kathryn Hefner
    Section on Behavioral Science and Genetics, Laboratory for Integrative Neuroscience, National Institute on Alcoholism and Alcohol Abuse, National Institutes of Health, Rockville, Maryland 20852, USA
    J Neurosci 28:8074-85. 2008
    ..This common inbred strain provides a novel model for studying impaired fear extinction in anxiety disorders...
  8. ncbi request reprint Short-term and long-term effects of postnatal exposure to an adult male in C57BL/6J mice
    Kathryn Hefner
    Section on Behavioral Science and Genetics, Laboratory for Integrative Neuroscience, National Institute on Alcohol Abuse and Alcoholism, NIH, Rockville, MD 20852 9411, USA
    Behav Brain Res 182:344-8. 2007
    ..Further studies will be needed to determine whether alternative mouse strains, exposure protocols or adult behavioral assays will produce a different pattern of short-term and long-term effects...
  9. pmc Desipramine potentiation of the acute depressant effects of ethanol: modulation by alpha2-adrenoreceptors and stress
    Janel M Boyce-Rustay
    Laboratory for Integrative Neuroscience, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Rockville, MD, USA
    Neuropharmacology 55:803-11. 2008
    ....
  10. pmc Reduced alcohol intake and reward associated with impaired endocannabinoid signaling in mice with a deletion of the glutamate transporter GLAST
    Rose Marie Karlsson
    Laboratory of Clinical and Translational Studies, National Institute on Alcoholism and Alcohol Abuse, NIH, 10 Center Drive, 1 5330, Bethesda, MD 20892 1108, USA
    Neuropharmacology 63:181-9. 2012
    ..Endocannabinoid signaling appears to be down-regulated upstream of the CB1 receptor as a result of the GLAST deletion, and is a candidate mechanism behind the reduction of alcohol reward observed...
  11. doi request reprint Variation in mouse basolateral amygdala volume is associated with differences in stress reactivity and fear learning
    Rebecca J Yang
    Section on Behavioral Science and Genetics, Laboratory for Integrative Neuroscience, National Institute on Alcohol Abuse and Alcoholism, NIH, Rockville, MD 20852 9411, USA
    Neuropsychopharmacology 33:2595-604. 2008
    ....
  12. pmc Does gene deletion of AMPA GluA1 phenocopy features of schizoaffective disorder?
    Paul J Fitzgerald
    Section on Behavioral Science and Genetics, Laboratory for Integrative Neuroscience, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD 20852 9411, USA
    Neurobiol Dis 40:608-21. 2010
    ..Collectively, these findings demonstrate mania-related abnormalities in GluA1 KO and, combined with previous findings, suggest this mutant may provide a novel model of features of schizoaffective disorder...
  13. pmc Comparison of dopamine D1 and D5 receptor knockout mice for cocaine locomotor sensitization
    Rose Marie Karlsson
    Section on Behavioral Science and Genetics, Laboratory for Integrative Neuroscience, National Institute on Alcohol Abuse and Alcoholism, 5625 Fishers Lane Rm 2N09, Rockville, MD 20852 9411, USA
    Psychopharmacology (Berl) 200:117-27. 2008
    ..The relative roles of D1R and D5R subtypes in mediating these effects are not clear...
  14. pmc Role of major NMDA or AMPA receptor subunits in MK-801 potentiation of ethanol intoxication
    Benjamin Palachick
    Section on Behavioral Science and Genetics, Laboratory for Integrative Neuroscience, National Institute on Alcohol Abuse and Alcoholism, 5625 Fishers Lane Room 2N09, Rockville, MD 20852 9411, USA
    Alcohol Clin Exp Res 32:1479-92. 2008
    ..N-methyl-D-aspartate receptor (NMDAR) antagonists such as MK-801 (dizocilpine) interact with EtOH at the behavioral level, but the molecular basis of this interaction is unclear...
  15. pmc Association of mouse Dlg4 (PSD-95) gene deletion and human DLG4 gene variation with phenotypes relevant to autism spectrum disorders and Williams' syndrome
    Michael Feyder
    Section on Behavioral Science and Genetics, Laboratory for Integrative Neuroscience, National Institute on Alcoholism and Alcohol Abuse, Rockville, MD 20852 9411, USA
    Am J Psychiatry 167:1508-17. 2010
    ..PSD-95 (postsynaptic density-95, DLG4) orchestrates protein-protein interactions at excitatory synapses and is a major functional bridge interconnecting a neurexinneuroligin-SHANK pathway implicated in autism spectrum disorders...
  16. pmc A novel role for PSD-95 in mediating ethanol intoxication, drinking and place preference
    Marguerite C Camp
    Section on Behavioral Science and Genetics, Laboratory for Integrative Neuroscience, National Institute on Alcohol Abuse and Alcoholism NIH, 5625 Fishers Ln, Rockville, MD 20852 1798, USA
    Addict Biol 16:428-39. 2011
    ..These data reveal a major, novel role for PSD-95 in mediating EtOH behaviors, and add to growing evidence that PSD-95 is a key mediator of the effects of multiple abused drugs...